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The map label for this gene is degS [C]

Identifier: 192291084

GI number: 192291084

Start: 2937340

End: 2938584

Strand: Reverse

Name: degS [C]

Synonym: Rpal_2705

Alternate gene names: 192291084

Gene position: 2938584-2937340 (Counterclockwise)

Preceding gene: 192291085

Following gene: 192291082

Centisome position: 51.16

GC content: 63.37

Gene sequence:

>1245_bases
ATGAAGCACACAACATTCGCAGTGCGGCTCGTGCACCCGCCCCGCAAAGCACTTCCGCGGAAGGACCTCCTCGCGCGGGC
GCTCGCTGCATTGATGTTTGTCGGATCGATCGCCTGCGCAGCAGAGGCCCGCTGCGGCGACCTCAACATCGATAAGTCAT
TCGGCAAGGTCTCGGGCTGGGACGTCGGATTCAGCAAGAGCGTCGGCGGTTGCCTCGCCGCGGCGACCTATCAGGATCGA
ACGACGGTCTGGTTCGGCTTCGCCGGCGACAAGCCGAGCGCCTACATCGCCTTCACCAATCCGCGCTGGGCGTCGGTCGA
GGTCGACGGCCAGTACGACATGCAACTCGTCATGGGTCGCACCCGGTGGAACGGCGAATTCATCGGCTTCGAGCGAAGCA
CTGAAAAGGGTGTGTTCTCGGGCAACCTCAAGACCGAGTTCATGGTGGAGCTCGCCGAGTCCGGCGGCGTCGGCGTGTTC
CTCAATCGGCGCCGAGTCGCAGCGCTGTCGTTGGATGGCTCGCGACGCGCGCTCGAAGCGGTGTTGTCGTGCCAGAAGGC
GCTCATGACGGCGCAGAGCGACACCCGCGACGAACCTTCAACGGACACCAAGCCGAAGCGCCATACCAAGAGCTCAGGCA
CTGGCTTCTACGTCTCGGACAGCGGCCATATCGTGACCAATCACCACGTCATCGCCGAGTGTTCGACCATCAACGTGCTG
CCTCCAGGCGGGGCCGCCGTGAGCGCTACCCTCGTCGCGAAGGACAAGACCAACGATCTAGCGATCCTGAAGACGGCGTC
GTCACCGGCTGCCATTCCGGGCCTGCGATCGCAGATGCGGCTCGGCGAAGCGGTTTACGTCTTCGGCTTCCCGCTGACCG
GCATCCTGTCGACCTCCGGCAATTTCACCGCCGGCGCGATCACCGCGACGACGGGAATGGAAGACGACACCCGGCTTGCA
CAGATCTCGGCGCCGGTTCAGCCGGGCAACAGCGGCGGTCCGCTGCTGGACAAGTACGGCAACGTCATCGGCGTGATCGT
CTCGAAGCTCAATGCCTTGAACATCGCCGCGGCGACCAAGGACATTCCGCAGAACGTCAACTTTGCGATCAAGACCGGTA
TCGCAACCAACTTCCTCGATTCCAGCGGTGTGGTCCCGACCGGCAAGGTGAGCACACGCGAGCTTGCGCCCGAGGCGATC
GCCGACCTCGCGAAGATCTTTACCGTTCAGGTGCTCTGCAACTGA

Upstream 100 bases:

>100_bases
CGTTGCCGTTTCGAAAACACGTCCGGCCAGAGACTAAGCGTCCACCGCCGGACAAAGGCACCTCCACCAGAGGCGCAGCC
ATTTTCCAGTGCGAAGGCCG

Downstream 100 bases:

>100_bases
GCGGTGCTCGTCTGCCCGCCGTCACAAGCGCTGCCGATGGCGGAAGCAAGCACAGCCTCACGCTCGACCAACATTGCTAA
TCGCGCTCCTGCCTTCCTTG

Product: peptidase S1 and S6 chymotrypsin/Hap

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MKHTTFAVRLVHPPRKALPRKDLLARALAALMFVGSIACAAEARCGDLNIDKSFGKVSGWDVGFSKSVGGCLAAATYQDR
TTVWFGFAGDKPSAYIAFTNPRWASVEVDGQYDMQLVMGRTRWNGEFIGFERSTEKGVFSGNLKTEFMVELAESGGVGVF
LNRRRVAALSLDGSRRALEAVLSCQKALMTAQSDTRDEPSTDTKPKRHTKSSGTGFYVSDSGHIVTNHHVIAECSTINVL
PPGGAAVSATLVAKDKTNDLAILKTASSPAAIPGLRSQMRLGEAVYVFGFPLTGILSTSGNFTAGAITATTGMEDDTRLA
QISAPVQPGNSGGPLLDKYGNVIGVIVSKLNALNIAAATKDIPQNVNFAIKTGIATNFLDSSGVVPTGKVSTRELAPEAI
ADLAKIFTVQVLCN

Sequences:

>Translated_414_residues
MKHTTFAVRLVHPPRKALPRKDLLARALAALMFVGSIACAAEARCGDLNIDKSFGKVSGWDVGFSKSVGGCLAAATYQDR
TTVWFGFAGDKPSAYIAFTNPRWASVEVDGQYDMQLVMGRTRWNGEFIGFERSTEKGVFSGNLKTEFMVELAESGGVGVF
LNRRRVAALSLDGSRRALEAVLSCQKALMTAQSDTRDEPSTDTKPKRHTKSSGTGFYVSDSGHIVTNHHVIAECSTINVL
PPGGAAVSATLVAKDKTNDLAILKTASSPAAIPGLRSQMRLGEAVYVFGFPLTGILSTSGNFTAGAITATTGMEDDTRLA
QISAPVQPGNSGGPLLDKYGNVIGVIVSKLNALNIAAATKDIPQNVNFAIKTGIATNFLDSSGVVPTGKVSTRELAPEAI
ADLAKIFTVQVLCN
>Mature_414_residues
MKHTTFAVRLVHPPRKALPRKDLLARALAALMFVGSIACAAEARCGDLNIDKSFGKVSGWDVGFSKSVGGCLAAATYQDR
TTVWFGFAGDKPSAYIAFTNPRWASVEVDGQYDMQLVMGRTRWNGEFIGFERSTEKGVFSGNLKTEFMVELAESGGVGVF
LNRRRVAALSLDGSRRALEAVLSCQKALMTAQSDTRDEPSTDTKPKRHTKSSGTGFYVSDSGHIVTNHHVIAECSTINVL
PPGGAAVSATLVAKDKTNDLAILKTASSPAAIPGLRSQMRLGEAVYVFGFPLTGILSTSGNFTAGAITATTGMEDDTRLA
QISAPVQPGNSGGPLLDKYGNVIGVIVSKLNALNIAAATKDIPQNVNFAIKTGIATNFLDSSGVVPTGKVSTRELAPEAI
ADLAKIFTVQVLCN

Specific function: Unknown

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S1B family [H]

Homologues:

Organism=Homo sapiens, GI24308541, Length=178, Percent_Identity=34.8314606741573, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI4506141, Length=182, Percent_Identity=32.4175824175824, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI22129776, Length=181, Percent_Identity=32.5966850828729, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1789630, Length=211, Percent_Identity=29.3838862559242, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24646839, Length=231, Percent_Identity=29.8701298701299, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 43764; Mature: 43764

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHTTFAVRLVHPPRKALPRKDLLARALAALMFVGSIACAAEARCGDLNIDKSFGKVSGW
CCCEEEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
DVGFSKSVGGCLAAATYQDRTTVWFGFAGDKPSAYIAFTNPRWASVEVDGQYDMQLVMGR
CCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCEEEEECCCCEEEEEECCCCCEEEEEEC
TRWNGEFIGFERSTEKGVFSGNLKTEFMVELAESGGVGVFLNRRRVAALSLDGSRRALEA
CCCCCEEEEEECCCCCCEEECCCCCEEEEEECCCCCEEEEEECCEEEEEECCCCHHHHHH
VLSCQKALMTAQSDTRDEPSTDTKPKRHTKSSGTGFYVSDSGHIVTNHHVIAECSTINVL
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCEEEEEEEEEEEE
PPGGAAVSATLVAKDKTNDLAILKTASSPAAIPGLRSQMRLGEAVYVFGFPLTGILSTSG
CCCCCEEEEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHCCCEEEEEECCCEEEEECCC
NFTAGAITATTGMEDDTRLAQISAPVQPGNSGGPLLDKYGNVIGVIVSKLNALNIAAATK
CEEECEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHCCEEEEECCC
DIPQNVNFAIKTGIATNFLDSSGVVPTGKVSTRELAPEAIADLAKIFTVQVLCN
CCCCCCCEEEECCCEEECCCCCCCCCCCCCCHHHCCHHHHHHHHHHEEEEEEEC
>Mature Secondary Structure
MKHTTFAVRLVHPPRKALPRKDLLARALAALMFVGSIACAAEARCGDLNIDKSFGKVSGW
CCCEEEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
DVGFSKSVGGCLAAATYQDRTTVWFGFAGDKPSAYIAFTNPRWASVEVDGQYDMQLVMGR
CCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCEEEEECCCCEEEEEECCCCCEEEEEEC
TRWNGEFIGFERSTEKGVFSGNLKTEFMVELAESGGVGVFLNRRRVAALSLDGSRRALEA
CCCCCEEEEEECCCCCCEEECCCCCEEEEEECCCCCEEEEEECCEEEEEECCCCHHHHHH
VLSCQKALMTAQSDTRDEPSTDTKPKRHTKSSGTGFYVSDSGHIVTNHHVIAECSTINVL
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCEEEEEEEEEEEE
PPGGAAVSATLVAKDKTNDLAILKTASSPAAIPGLRSQMRLGEAVYVFGFPLTGILSTSG
CCCCCEEEEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHCCCEEEEEECCCEEEEECCC
NFTAGAITATTGMEDDTRLAQISAPVQPGNSGGPLLDKYGNVIGVIVSKLNALNIAAATK
CEEECEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHCCEEEEECCC
DIPQNVNFAIKTGIATNFLDSSGVVPTGKVSTRELAPEAIADLAKIFTVQVLCN
CCCCCCCEEEECCCEEECCCCCCCCCCCCCCHHHCCHHHHHHHHHHEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]