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The map label for this gene is pcbC [H]

Identifier: 192290985

GI number: 192290985

Start: 2813358

End: 2814404

Strand: Reverse

Name: pcbC [H]

Synonym: Rpal_2602

Alternate gene names: 192290985

Gene position: 2814404-2813358 (Counterclockwise)

Preceding gene: 192290992

Following gene: 192290982

Centisome position: 49.0

GC content: 65.14

Gene sequence:

>1047_bases
ATGACAGCCTCGCCCTCGCAGCTTCCCGTCCTCGACCTCAGCCGGTTTCGCAGCGACACCGCTGAGCGCGCGGAATTTCT
CCGCGATGTCCGCAACGCCGCATTCGGTCCTGGATTTTTCTACCTTGTCGGACATGGCATCTCGGACCGGCTGATCCGGG
ACGTGCTGTTTGCCTCGCGTAATTTCTTTGCGCTCCCTGAGGCGGACAAGCTCGATATCGAGATGATCAACTCGCCGCAT
TTCCGCGGTTACACCCGCGCCGGCCGGGAATTCACCCGTGGCCAGCCGGATTGGCGCGAACAGGTCGATGTCGGCGCCGA
ACGCGAGGCGTTCCCCCTCAGCCGTTCGGCGCCACCCTGGACCAGGTTGCAGGGCCCGAACCAATGGCCCGACGCGCTGC
CGGAACTGAAGCCGCTGCTGCTGCGCTATCAGCAGGAGGTGACGGAGCTAGCGATCAAAGTGCTGCGGGTGTTCGCCGCC
GCGCTCGGCCAGGCCGAGGACGTGTTTGAACCGATTTACGTGCCCTCGCCCAACCAGCTGATCAAGATCATCCGCTATCC
CGGCCGCGCAGCGGACGAGAGCGATCAGGGCGTCGGTGCACACAAGGATTCCGGCTTCGTCACCATCCTACTGCAGGACA
CCGTGGCCGGCTTGCAGGTCGAAACTGCTGACGGCTGGATCGATGCACCGCCCCTCCCGGGCTCGTTCGTGGTCAATATC
GGCGAGATCCTCGAGCTGGCGTCGAACGGCGCGCTGCGCGCCAATGTGCACAGGGTGGTGTCACCGCCGCCGGACACCGA
CCGGCTGTCGGTTGCGTTCTTCCTTGGCGCGCGGCTTGACGCCACCGTGCCGGTGCTGACGCTGCCGCCGGAGCTCGCCG
ATTACGCCCGCGGCGTCACGCAGGATCCGCAGAACCCGTTGTTCCGCGACGTCGGACGCAACTATCTCAAGGGCCGGCTG
CGTTCACACCCGGACGTGGCCGAGCGTCACCATGCTGATCTGTTGGACGAATATTCCATCAAGCCGGGCCTCGCGGCGGC
GTATTAG

Upstream 100 bases:

>100_bases
ACGGATCAACAGCACAACCGATGCTATTTTCGCCGAAGCCTCGACAGCATGTCGGCCGGTGCGCATCATTCGAAGCAGCC
GACACAGTTGGAGCCCATCG

Downstream 100 bases:

>100_bases
ACGGTCACGAGCGCTCCCATTGATTGCTTCTAAAACAATAAAGATGCCCGGCACATGCCGGGCATCGAAGATAGCTCAGA
AGCCGTTGTCCGGCCGGCCG

Product: 2OG-Fe(II) oxygenase

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MTASPSQLPVLDLSRFRSDTAERAEFLRDVRNAAFGPGFFYLVGHGISDRLIRDVLFASRNFFALPEADKLDIEMINSPH
FRGYTRAGREFTRGQPDWREQVDVGAEREAFPLSRSAPPWTRLQGPNQWPDALPELKPLLLRYQQEVTELAIKVLRVFAA
ALGQAEDVFEPIYVPSPNQLIKIIRYPGRAADESDQGVGAHKDSGFVTILLQDTVAGLQVETADGWIDAPPLPGSFVVNI
GEILELASNGALRANVHRVVSPPPDTDRLSVAFFLGARLDATVPVLTLPPELADYARGVTQDPQNPLFRDVGRNYLKGRL
RSHPDVAERHHADLLDEYSIKPGLAAAY

Sequences:

>Translated_348_residues
MTASPSQLPVLDLSRFRSDTAERAEFLRDVRNAAFGPGFFYLVGHGISDRLIRDVLFASRNFFALPEADKLDIEMINSPH
FRGYTRAGREFTRGQPDWREQVDVGAEREAFPLSRSAPPWTRLQGPNQWPDALPELKPLLLRYQQEVTELAIKVLRVFAA
ALGQAEDVFEPIYVPSPNQLIKIIRYPGRAADESDQGVGAHKDSGFVTILLQDTVAGLQVETADGWIDAPPLPGSFVVNI
GEILELASNGALRANVHRVVSPPPDTDRLSVAFFLGARLDATVPVLTLPPELADYARGVTQDPQNPLFRDVGRNYLKGRL
RSHPDVAERHHADLLDEYSIKPGLAAAY
>Mature_347_residues
TASPSQLPVLDLSRFRSDTAERAEFLRDVRNAAFGPGFFYLVGHGISDRLIRDVLFASRNFFALPEADKLDIEMINSPHF
RGYTRAGREFTRGQPDWREQVDVGAEREAFPLSRSAPPWTRLQGPNQWPDALPELKPLLLRYQQEVTELAIKVLRVFAAA
LGQAEDVFEPIYVPSPNQLIKIIRYPGRAADESDQGVGAHKDSGFVTILLQDTVAGLQVETADGWIDAPPLPGSFVVNIG
EILELASNGALRANVHRVVSPPPDTDRLSVAFFLGARLDATVPVLTLPPELADYARGVTQDPQNPLFRDVGRNYLKGRLR
SHPDVAERHHADLLDEYSIKPGLAAAY

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI28572124, Length=295, Percent_Identity=24.406779661017, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 38565; Mature: 38434

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASPSQLPVLDLSRFRSDTAERAEFLRDVRNAAFGPGFFYLVGHGISDRLIRDVLFASR
CCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCC
NFFALPEADKLDIEMINSPHFRGYTRAGREFTRGQPDWREQVDVGAEREAFPLSRSAPPW
CEEECCCCCCCCEEECCCCCCCCHHHHCHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCC
TRLQGPNQWPDALPELKPLLLRYQQEVTELAIKVLRVFAAALGQAEDVFEPIYVPSPNQL
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHH
IKIIRYPGRAADESDQGVGAHKDSGFVTILLQDTVAGLQVETADGWIDAPPLPGSFVVNI
HHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEECCCCCCCCCCCCCHHEECH
GEILELASNGALRANVHRVVSPPPDTDRLSVAFFLGARLDATVPVLTLPPELADYARGVT
HHHHHHHCCCCEEECHHEECCCCCCCCCEEEEEECCCCCCCCCCEEECCHHHHHHHCCCC
QDPQNPLFRDVGRNYLKGRLRSHPDVAERHHADLLDEYSIKPGLAAAY
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TASPSQLPVLDLSRFRSDTAERAEFLRDVRNAAFGPGFFYLVGHGISDRLIRDVLFASR
CCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCC
NFFALPEADKLDIEMINSPHFRGYTRAGREFTRGQPDWREQVDVGAEREAFPLSRSAPPW
CEEECCCCCCCCEEECCCCCCCCHHHHCHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCC
TRLQGPNQWPDALPELKPLLLRYQQEVTELAIKVLRVFAAALGQAEDVFEPIYVPSPNQL
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHH
IKIIRYPGRAADESDQGVGAHKDSGFVTILLQDTVAGLQVETADGWIDAPPLPGSFVVNI
HHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEECCCCCCCCCCCCCHHEECH
GEILELASNGALRANVHRVVSPPPDTDRLSVAFFLGARLDATVPVLTLPPELADYARGVT
HHHHHHHCCCCEEECHHEECCCCCCCCCEEEEEECCCCCCCCCCEEECCHHHHHHHCCCC
QDPQNPLFRDVGRNYLKGRLRSHPDVAERHHADLLDEYSIKPGLAAAY
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3216857; 8639682 [H]