Click here to switch to the map view.

The map label for this gene is cutL [H]

Identifier: 192290872

GI number: 192290872

Start: 2683629

End: 2686004

Strand: Reverse

Name: cutL [H]

Synonym: Rpal_2488

Alternate gene names: 192290872

Gene position: 2686004-2683629 (Counterclockwise)

Preceding gene: 192290874

Following gene: 192290869

Centisome position: 46.76

GC content: 67.42

Gene sequence:

>2376_bases
ATGCAGGACCGCCCCGCCATCGCGTCGCTCGACACTTCCCTCGCGCTGCACAAATTCGGCGTGGGCCAGCCGGTCCGGCG
CAAGGAGGACGAAACTCTGCTGCGCGGCAAAGGCCGCTACACCGACGACTGCAATCCGCCGGGGCAGTTCTACGCCGTGA
TGGTGCGCAGCCCGCATCCGCACGGCATCATCCGCGGCATCGGCACCGAGGCCGCCAAGGCAATGCCCGGCGTCTGCGCG
ATCTACACCAGCGCGGACCTCGCTTCAGCCGGCTACGCTCCGTTCAGCTCTGGTCTGCCGCTGAAGAGCCGTGACGGCAC
GCCGCTGAAGCAGACCCATCACGGCGCGCTGCCCACCGACAAGGTCCGCTTCGTCGGCGAAGCGGTCGCCTGCGTGGTCG
CCAAGACGCTGGCGCAGGCGCGCGATGCCGCCGAAGCCGTCGAACTCGACATCGAGCCGCTGCCCGCCGTCACCGATGCC
GAAGCCGCGATGCAGCCTGGCGCGCCGCAGCTCTATGATCACATCGAGAACAACGTCGCGCTCGACTATCACTTCGGCGA
CACCGCGGCAGTGAACGCAGCCTTCGCCGCGGCCGCGCATGTCACCACGCTCGACATCGAGAACACCCGCGTCGCCGCGG
TGCCGATGGAGCCGCGGGTCGGGCTAGCCTCCTACGATCAGCAGAACGGCCGCTACACCATTCAGCTTCCGACCCAGGGC
GTCTCCGGCAATCGCAATACGCTCGCCAAACTACTCGGCGTGCCGACCGACAAGGTGCGGGTGCTGACCGGCCAGGTCGG
CGGCTCGTTCGGGATGAAGAACATCTCTTACCCCGAGTACATCTGTATTCTGCACGCCGCCAAGACGCTCGGCCGCCCGG
TGAAGTGGACCGACGAGCGCTCGACCAGCTTTCTGTCTGACAGCCAGGGCCGCGGCCAGCAGATCCGCGCCGAACTGGCG
CTGGATGCCGGCGGACGCTTTTTGGCGATCCGCCTGTCCGGCACCGGCAATCTCGGCGCGTATATCACCGGCGTCGCGCC
GCTGCCGCTGTCGCTCAACACCGGCAAGAACATCGGCAGCGTGTACCGGACGCCGCTGCTCAGCGTCGATATCAAATGCG
TCGTCACCAACGTCACGCTGATGGGTGCCTATCGCGGTGCCGGCCGGCCTGAGGCCAACTACTTCCTGGAGCGGCTGATC
GATCGCGCCGCCGACGAGATGGGGATCGACCGCCTCACCTTGCGCAAGCGCAACTTCATCAAGCCGACGCAGATGCCGTT
CACCGCCTGCTCCGGTGTCACCTACGACAGCGGCGATTTCGCCGGCGTGTTCGGCCAAGCATTGGAACTGTCCGACTATG
ACGGCTTCGCCAAGCGCAAGAAGGACGCGCGCAAGGCCGGCAAGCTGCGCGGCATCGCGGTCGGCTCCTATCTGGAAGTA
ACGGCGCCGCCGAACCCCGAACTCGGCAAGATCGTGTTCGAGGCCGATGGCACGGTGCGGCTGATCACCGGCACGCTCGA
CTATGGCCAGGGCCATGCGACGCCGTTCGCGCAGGTGCTCAGCACGTTTCTCGGCGTGCCGTTCGAGCGCATCCGGCTCG
AACAGGGCGACAGCGATATTGTCCACACCGGCAACGGCACCGGCGGATCGCGCTCGATCACCGCGAGCGGCATGGCGATC
GTCGAGGCGTCGCAGAAGGTGATCGCCAAGGGCAAGAGCGCTGCCGCGCATCTGCTGGAGACCGCCGAAGCCGACATCGA
GTTCGCCGATGGCCGTTTCACCGTCGCCGGCACCGACCGCAGCATCGGCATCATGGACCTGGCACAGCGGCTGCGCGGCG
CCGAGCCGCCGGAGGGCGTGCCGGCTTCGCTCGACGTCGATCACACCACCGAGGGCGTCCCCTCTGCCTTCCCCAACGGC
TGCCATGTGGCGGAGGTCGAGATCGATCCCGACACCGGCGTCACCCGCGTGGTGCGCTACACCGCGGTCAACGACTTCGG
CACCGTGGTCAATCCGATGATCGTCGCCGGCCAGTTGCACGGCGGCGTCGCCCAAGGCATCGGCCAGGCGCTGATGGAGA
AGGTCTCGTACAACGCAGACGGCCAGCCGATCACCGGCTCGCTGCAGGACTACGCGCTGCCGCGCGCCGAGGATATCCCG
CTGATGACTGTGGGCGATCACCCGGTGCCGGCCAAGACCAATCCGCTCGGCACCAAGGGCTGCGGCGAAGCCGGCTGCGC
CGGCTCGCTCGCCACCATCGTCAACGCTGCGCTCGATGCGCTGAAGGATTACGGCGTGACGACGCTCGACATGCCGCTGA
CGCCTGAGAAGGTGTGGCGCGCGATCCACGAGGCGAAGGCGAAGACAGCGGCGTGA

Upstream 100 bases:

>100_bases
ATCCGTTGGAACTATCAGCACTGACATTCCCCCGCGCAGAAACGCCGCCCCACGCGGCTTTTTCCCGTCCCGCGCGCCTC
TCAAGCCGGAACTCAGCCTC

Downstream 100 bases:

>100_bases
AACGCGGCCGCTGCGCATTTCTCAGGGGCGAGCCTGCCTTACTACGAAAAGTCATGCGCGGGCTTGACCCGCCTGCGCGG
CCGTAGCCGCTTCGGCGCGG

Product: molybdopterin binding aldehyde oxidase and xanthine dehydrogenase

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 791; Mature: 791

Protein sequence:

>791_residues
MQDRPAIASLDTSLALHKFGVGQPVRRKEDETLLRGKGRYTDDCNPPGQFYAVMVRSPHPHGIIRGIGTEAAKAMPGVCA
IYTSADLASAGYAPFSSGLPLKSRDGTPLKQTHHGALPTDKVRFVGEAVACVVAKTLAQARDAAEAVELDIEPLPAVTDA
EAAMQPGAPQLYDHIENNVALDYHFGDTAAVNAAFAAAAHVTTLDIENTRVAAVPMEPRVGLASYDQQNGRYTIQLPTQG
VSGNRNTLAKLLGVPTDKVRVLTGQVGGSFGMKNISYPEYICILHAAKTLGRPVKWTDERSTSFLSDSQGRGQQIRAELA
LDAGGRFLAIRLSGTGNLGAYITGVAPLPLSLNTGKNIGSVYRTPLLSVDIKCVVTNVTLMGAYRGAGRPEANYFLERLI
DRAADEMGIDRLTLRKRNFIKPTQMPFTACSGVTYDSGDFAGVFGQALELSDYDGFAKRKKDARKAGKLRGIAVGSYLEV
TAPPNPELGKIVFEADGTVRLITGTLDYGQGHATPFAQVLSTFLGVPFERIRLEQGDSDIVHTGNGTGGSRSITASGMAI
VEASQKVIAKGKSAAAHLLETAEADIEFADGRFTVAGTDRSIGIMDLAQRLRGAEPPEGVPASLDVDHTTEGVPSAFPNG
CHVAEVEIDPDTGVTRVVRYTAVNDFGTVVNPMIVAGQLHGGVAQGIGQALMEKVSYNADGQPITGSLQDYALPRAEDIP
LMTVGDHPVPAKTNPLGTKGCGEAGCAGSLATIVNAALDALKDYGVTTLDMPLTPEKVWRAIHEAKAKTAA

Sequences:

>Translated_791_residues
MQDRPAIASLDTSLALHKFGVGQPVRRKEDETLLRGKGRYTDDCNPPGQFYAVMVRSPHPHGIIRGIGTEAAKAMPGVCA
IYTSADLASAGYAPFSSGLPLKSRDGTPLKQTHHGALPTDKVRFVGEAVACVVAKTLAQARDAAEAVELDIEPLPAVTDA
EAAMQPGAPQLYDHIENNVALDYHFGDTAAVNAAFAAAAHVTTLDIENTRVAAVPMEPRVGLASYDQQNGRYTIQLPTQG
VSGNRNTLAKLLGVPTDKVRVLTGQVGGSFGMKNISYPEYICILHAAKTLGRPVKWTDERSTSFLSDSQGRGQQIRAELA
LDAGGRFLAIRLSGTGNLGAYITGVAPLPLSLNTGKNIGSVYRTPLLSVDIKCVVTNVTLMGAYRGAGRPEANYFLERLI
DRAADEMGIDRLTLRKRNFIKPTQMPFTACSGVTYDSGDFAGVFGQALELSDYDGFAKRKKDARKAGKLRGIAVGSYLEV
TAPPNPELGKIVFEADGTVRLITGTLDYGQGHATPFAQVLSTFLGVPFERIRLEQGDSDIVHTGNGTGGSRSITASGMAI
VEASQKVIAKGKSAAAHLLETAEADIEFADGRFTVAGTDRSIGIMDLAQRLRGAEPPEGVPASLDVDHTTEGVPSAFPNG
CHVAEVEIDPDTGVTRVVRYTAVNDFGTVVNPMIVAGQLHGGVAQGIGQALMEKVSYNADGQPITGSLQDYALPRAEDIP
LMTVGDHPVPAKTNPLGTKGCGEAGCAGSLATIVNAALDALKDYGVTTLDMPLTPEKVWRAIHEAKAKTAA
>Mature_791_residues
MQDRPAIASLDTSLALHKFGVGQPVRRKEDETLLRGKGRYTDDCNPPGQFYAVMVRSPHPHGIIRGIGTEAAKAMPGVCA
IYTSADLASAGYAPFSSGLPLKSRDGTPLKQTHHGALPTDKVRFVGEAVACVVAKTLAQARDAAEAVELDIEPLPAVTDA
EAAMQPGAPQLYDHIENNVALDYHFGDTAAVNAAFAAAAHVTTLDIENTRVAAVPMEPRVGLASYDQQNGRYTIQLPTQG
VSGNRNTLAKLLGVPTDKVRVLTGQVGGSFGMKNISYPEYICILHAAKTLGRPVKWTDERSTSFLSDSQGRGQQIRAELA
LDAGGRFLAIRLSGTGNLGAYITGVAPLPLSLNTGKNIGSVYRTPLLSVDIKCVVTNVTLMGAYRGAGRPEANYFLERLI
DRAADEMGIDRLTLRKRNFIKPTQMPFTACSGVTYDSGDFAGVFGQALELSDYDGFAKRKKDARKAGKLRGIAVGSYLEV
TAPPNPELGKIVFEADGTVRLITGTLDYGQGHATPFAQVLSTFLGVPFERIRLEQGDSDIVHTGNGTGGSRSITASGMAI
VEASQKVIAKGKSAAAHLLETAEADIEFADGRFTVAGTDRSIGIMDLAQRLRGAEPPEGVPASLDVDHTTEGVPSAFPNG
CHVAEVEIDPDTGVTRVVRYTAVNDFGTVVNPMIVAGQLHGGVAQGIGQALMEKVSYNADGQPITGSLQDYALPRAEDIP
LMTVGDHPVPAKTNPLGTKGCGEAGCAGSLATIVNAALDALKDYGVTTLDMPLTPEKVWRAIHEAKAKTAA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=792, Percent_Identity=25.5050505050505, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI91823271, Length=800, Percent_Identity=24.5, Blast_Score=127, Evalue=6e-29,
Organism=Escherichia coli, GI1789230, Length=760, Percent_Identity=27.7631578947368, Blast_Score=222, Evalue=6e-59,
Organism=Escherichia coli, GI1789246, Length=823, Percent_Identity=24.9088699878493, Blast_Score=202, Evalue=7e-53,
Organism=Escherichia coli, GI1786478, Length=790, Percent_Identity=27.3417721518987, Blast_Score=134, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17539860, Length=780, Percent_Identity=24.1025641025641, Blast_Score=155, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17540638, Length=718, Percent_Identity=22.8412256267409, Blast_Score=142, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI32566215, Length=515, Percent_Identity=25.631067961165, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI17737937, Length=722, Percent_Identity=24.2382271468144, Blast_Score=106, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 83522; Mature: 83522

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDRPAIASLDTSLALHKFGVGQPVRRKEDETLLRGKGRYTDDCNPPGQFYAVMVRSPHP
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEEECCCC
HGIIRGIGTEAAKAMPGVCAIYTSADLASAGYAPFSSGLPLKSRDGTPLKQTHHGALPTD
CHHEECCCCHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCHH
KVRFVGEAVACVVAKTLAQARDAAEAVELDIEPLPAVTDAEAAMQPGAPQLYDHIENNVA
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHCCCCCHHHHHHHCCCEE
LDYHFGDTAAVNAAFAAAAHVTTLDIENTRVAAVPMEPRVGLASYDQQNGRYTIQLPTQG
EEEECCCCHHHHHHHHHHEEEEEEEECCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCC
VSGNRNTLAKLLGVPTDKVRVLTGQVGGSFGMKNISYPEYICILHAAKTLGRPVKWTDER
CCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCC
STSFLSDSQGRGQQIRAELALDAGGRFLAIRLSGTGNLGAYITGVAPLPLSLNTGKNIGS
CCHHHCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCEEEEECCCCCEEECCCCCCHH
VYRTPLLSVDIKCVVTNVTLMGAYRGAGRPEANYFLERLIDRAADEMGIDRLTLRKRNFI
HHHCCCEEEEEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEHHHCCCC
KPTQMPFTACSGVTYDSGDFAGVFGQALELSDYDGFAKRKKDARKAGKLRGIAVGSYLEV
CCCCCCCHHHCCCEECCCCCHHHHHHHEECCCCCCHHHHHHHHHHHCCEEEEEECCEEEE
TAPPNPELGKIVFEADGTVRLITGTLDYGQGHATPFAQVLSTFLGVPFERIRLEQGDSDI
ECCCCCCCCEEEEECCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCCHHHEEECCCCCCE
VHTGNGTGGSRSITASGMAIVEASQKVIAKGKSAAAHLLETAEADIEFADGRFTVAGTDR
EECCCCCCCCCEEEECCEEEEHHHHHHHHCCCHHHHHHHHHHCCCEEEECCEEEEECCCC
SIGIMDLAQRLRGAEPPEGVPASLDVDHTTEGVPSAFPNGCHVAEVEIDPDTGVTRVVRY
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHEEEE
TAVNDFGTVVNPMIVAGQLHGGVAQGIGQALMEKVSYNADGQPITGSLQDYALPRAEDIP
EECCHHHHHHCCEEEEEHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCC
LMTVGDHPVPAKTNPLGTKGCGEAGCAGSLATIVNAALDALKDYGVTTLDMPLTPEKVWR
EEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHH
AIHEAKAKTAA
HHHHHHHHCCC
>Mature Secondary Structure
MQDRPAIASLDTSLALHKFGVGQPVRRKEDETLLRGKGRYTDDCNPPGQFYAVMVRSPHP
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEEECCCC
HGIIRGIGTEAAKAMPGVCAIYTSADLASAGYAPFSSGLPLKSRDGTPLKQTHHGALPTD
CHHEECCCCHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCHH
KVRFVGEAVACVVAKTLAQARDAAEAVELDIEPLPAVTDAEAAMQPGAPQLYDHIENNVA
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHCCCCCHHHHHHHCCCEE
LDYHFGDTAAVNAAFAAAAHVTTLDIENTRVAAVPMEPRVGLASYDQQNGRYTIQLPTQG
EEEECCCCHHHHHHHHHHEEEEEEEECCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCC
VSGNRNTLAKLLGVPTDKVRVLTGQVGGSFGMKNISYPEYICILHAAKTLGRPVKWTDER
CCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCC
STSFLSDSQGRGQQIRAELALDAGGRFLAIRLSGTGNLGAYITGVAPLPLSLNTGKNIGS
CCHHHCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCEEEEECCCCCEEECCCCCCHH
VYRTPLLSVDIKCVVTNVTLMGAYRGAGRPEANYFLERLIDRAADEMGIDRLTLRKRNFI
HHHCCCEEEEEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEHHHCCCC
KPTQMPFTACSGVTYDSGDFAGVFGQALELSDYDGFAKRKKDARKAGKLRGIAVGSYLEV
CCCCCCCHHHCCCEECCCCCHHHHHHHEECCCCCCHHHHHHHHHHHCCEEEEEECCEEEE
TAPPNPELGKIVFEADGTVRLITGTLDYGQGHATPFAQVLSTFLGVPFERIRLEQGDSDI
ECCCCCCCCEEEEECCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCCHHHEEECCCCCCE
VHTGNGTGGSRSITASGMAIVEASQKVIAKGKSAAAHLLETAEADIEFADGRFTVAGTDR
EECCCCCCCCCEEEECCEEEEHHHHHHHHCCCHHHHHHHHHHCCCEEEECCEEEEECCCC
SIGIMDLAQRLRGAEPPEGVPASLDVDHTTEGVPSAFPNGCHVAEVEIDPDTGVTRVVRY
CCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHEEEE
TAVNDFGTVVNPMIVAGQLHGGVAQGIGQALMEKVSYNADGQPITGSLQDYALPRAEDIP
EECCHHHHHHCCEEEEEHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCC
LMTVGDHPVPAKTNPLGTKGCGEAGCAGSLATIVNAALDALKDYGVTTLDMPLTPEKVWR
EEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHH
AIHEAKAKTAA
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]