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The map label for this gene is folB [H]

Identifier: 192290436

GI number: 192290436

Start: 2214488

End: 2214853

Strand: Reverse

Name: folB [H]

Synonym: Rpal_2043

Alternate gene names: 192290436

Gene position: 2214853-2214488 (Counterclockwise)

Preceding gene: 192290437

Following gene: 192290435

Centisome position: 38.56

GC content: 64.48

Gene sequence:

>366_bases
ATGAACGACACCATTTTCATTTCCGGCCTGGTGCTGCACGCCCGCCACGGCGTGATGGAGCACGAGACCGAGGTCGGCCA
ACGCTTCGTGATCGATCTCGAACTCAGCGCCGATCTGTCGGAGTCCTCGCGCACCGACCGGCTGTCCGACACGGTGTCGT
ATTCGAACGTGGTGGCGTGTACCACCGCGGCGTTCAAGGACGCCAACTACCGGTTGCTCGAGCGCGCCGCAGGCGCGGTG
GCCGATGCGATCCTTGCGAGTTTCGACAAGATCACCGCGGTGAAGGTGACGGTGCACAAGCCGCACGCGCCGATCCCGGC
GATCTTCGAGGACGTCGGCGTGATCATCACCCGCAGGCGGAGCTGA

Upstream 100 bases:

>100_bases
ATCTCATCGCGGTCGAGAACGGCGCCAAGATCATCCGCGCGCACGACGTCGCCGCGACGTCGCAGGCATTGAAAGTCGCC
CACGCCATCAGGGACAGCCG

Downstream 100 bases:

>100_bases
GATGCCGCGCGCCCTGATCGCGCTCGGCGGCAATGTCGGCGACGTCCGCGCCACCTTCGACAAGGCGATCGCCAACATCT
GTGGCATGACCCAAGCCGAA

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 121; Mature: 121

Protein sequence:

>121_residues
MNDTIFISGLVLHARHGVMEHETEVGQRFVIDLELSADLSESSRTDRLSDTVSYSNVVACTTAAFKDANYRLLERAAGAV
ADAILASFDKITAVKVTVHKPHAPIPAIFEDVGVIITRRRS

Sequences:

>Translated_121_residues
MNDTIFISGLVLHARHGVMEHETEVGQRFVIDLELSADLSESSRTDRLSDTVSYSNVVACTTAAFKDANYRLLERAAGAV
ADAILASFDKITAVKVTVHKPHAPIPAIFEDVGVIITRRRS
>Mature_121_residues
MNDTIFISGLVLHARHGVMEHETEVGQRFVIDLELSADLSESSRTDRLSDTVSYSNVVACTTAAFKDANYRLLERAAGAV
ADAILASFDKITAVKVTVHKPHAPIPAIFEDVGVIITRRRS

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

Organism=Escherichia coli, GI87082204, Length=116, Percent_Identity=31.8965517241379, Blast_Score=63, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 13209; Mature: 13209

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTIFISGLVLHARHGVMEHETEVGQRFVIDLELSADLSESSRTDRLSDTVSYSNVVAC
CCCEEEEHHEEEEHHCCCHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHHHCCCCEEEE
TTAAFKDANYRLLERAAGAVADAILASFDKITAVKVTVHKPHAPIPAIFEDVGVIITRRR
EHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHCCCEEEEECC
S
C
>Mature Secondary Structure
MNDTIFISGLVLHARHGVMEHETEVGQRFVIDLELSADLSESSRTDRLSDTVSYSNVVAC
CCCEEEEHHEEEEHHCCCHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHHHCCCCEEEE
TTAAFKDANYRLLERAAGAVADAILASFDKITAVKVTVHKPHAPIPAIFEDVGVIITRRR
EHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHCCCEEEEECC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]