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The map label for this gene is fabG [H]

Identifier: 192290275

GI number: 192290275

Start: 2022359

End: 2023141

Strand: Reverse

Name: fabG [H]

Synonym: Rpal_1879

Alternate gene names: 192290275

Gene position: 2023141-2022359 (Counterclockwise)

Preceding gene: 192290278

Following gene: 192290273

Centisome position: 35.22

GC content: 68.97

Gene sequence:

>783_bases
GTGGATCTGGGAATCAAGGGCCGCCGCGCGCTGGTGTGCGCATCGAGCAAGGGACTGGGCCGCGGCTGCGCTGCGGCGCT
CGCCGCCGAAGGCGTGCATGTGACGATGACTGCACGCGGCGCCGAAGCGCTGGCGCAGGCCGCGGCGGAGCTGCGCAAGG
CCTATCCCGATGTCGAGATCATCGAGGTCGCCGGCGACATCACCACGCCGGAAGGCCGCGCCGCCGCGCTGGCGGCCTGC
CCGGAGCCGGACATCCTGATCAACAATGCCGGCGGCCCGCCGCCCGGCGATTTCCGCAACTGGACCCGCGACGACTGGAT
CAAGGCGCTCGACGCCAACATGCTGACGCCGATCGAACTGATCAAGGCGACGGTCGACAAGATGATCGAGCGCAAGTTCG
GCCGCATCGTCAACATCACCTCGGCCGCCGTGAAAGCTCCGATCGACGTGCTCGGCCTGTCGAACGGCGCACGCTCCGGT
CTGACCGGCTTCGTCGCCGGCCTGTCGCGCAAGACCGTTCGTCACAACGTGACGATCAATGCGCTGCTGCCCGGCCCGTT
CGACACCGATCGGCTGCGCGGCGTCGCCGCCGGTCAGGCCAAGGCGTCCGGCAAGCCGGCCGAGCAGATCCTGGAAGCGC
GGAAGAATGAAAACCCGGCGGGACGCTTCGGCACGCCGGATGAATTCGGCGCCGCCTGTGCGTTCCTGTGCAGCGTCCAC
GCCGGCTACATCACCGGCCAGAACCTGCTGCTCGACGGCGGCGCGTTCCCGGGCACGATGTAA

Upstream 100 bases:

>100_bases
TCCCGTTGATGCGTTATGCGTTGCCCTCCCCTTACCATGCCGGAGCCGCTTGGCTAGAGTACCGCCCTCACCGACATCGT
CATCCATGCTGGAGTGAAAC

Downstream 100 bases:

>100_bases
CGGCCGCCCGACGACGAAAGACCGGCGGTGCGATGCCGCCGGTCTTCAGCTTACTTCGGCGCCGTCATCACGATGCGCAC
CAGATCGGTGGCATTGCGGG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MDLGIKGRRALVCASSKGLGRGCAAALAAEGVHVTMTARGAEALAQAAAELRKAYPDVEIIEVAGDITTPEGRAAALAAC
PEPDILINNAGGPPPGDFRNWTRDDWIKALDANMLTPIELIKATVDKMIERKFGRIVNITSAAVKAPIDVLGLSNGARSG
LTGFVAGLSRKTVRHNVTINALLPGPFDTDRLRGVAAGQAKASGKPAEQILEARKNENPAGRFGTPDEFGAACAFLCSVH
AGYITGQNLLLDGGAFPGTM

Sequences:

>Translated_260_residues
MDLGIKGRRALVCASSKGLGRGCAAALAAEGVHVTMTARGAEALAQAAAELRKAYPDVEIIEVAGDITTPEGRAAALAAC
PEPDILINNAGGPPPGDFRNWTRDDWIKALDANMLTPIELIKATVDKMIERKFGRIVNITSAAVKAPIDVLGLSNGARSG
LTGFVAGLSRKTVRHNVTINALLPGPFDTDRLRGVAAGQAKASGKPAEQILEARKNENPAGRFGTPDEFGAACAFLCSVH
AGYITGQNLLLDGGAFPGTM
>Mature_260_residues
MDLGIKGRRALVCASSKGLGRGCAAALAAEGVHVTMTARGAEALAQAAAELRKAYPDVEIIEVAGDITTPEGRAAALAAC
PEPDILINNAGGPPPGDFRNWTRDDWIKALDANMLTPIELIKATVDKMIERKFGRIVNITSAAVKAPIDVLGLSNGARSG
LTGFVAGLSRKTVRHNVTINALLPGPFDTDRLRGVAAGQAKASGKPAEQILEARKNENPAGRFGTPDEFGAACAFLCSVH
AGYITGQNLLLDGGAFPGTM

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=253, Percent_Identity=30.0395256916996, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI5031737, Length=254, Percent_Identity=27.5590551181102, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=25.2918287937743, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI66933014, Length=233, Percent_Identity=29.1845493562232, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=26.8292682926829, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI7705925, Length=258, Percent_Identity=26.7441860465116, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI33667109, Length=217, Percent_Identity=28.110599078341, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI15277342, Length=263, Percent_Identity=25.4752851711027, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=260, Percent_Identity=31.9230769230769, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=29.3650793650794, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI87082160, Length=259, Percent_Identity=26.6409266409266, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=23.046875, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1789208, Length=260, Percent_Identity=26.1538461538462, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082100, Length=270, Percent_Identity=27.7777777777778, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=24.5136186770428, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=24.904214559387, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=31.640625, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=30.7984790874525, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI193204405, Length=269, Percent_Identity=30.1115241635688, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=28.0898876404494, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=28.4615384615385, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17562908, Length=269, Percent_Identity=28.6245353159851, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=28.3018867924528, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=29.6153846153846, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=29.6153846153846, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=258, Percent_Identity=27.906976744186, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=27.3764258555133, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=28.5171102661597, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=259, Percent_Identity=27.027027027027, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=29.0566037735849, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=256, Percent_Identity=30.078125, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=260, Percent_Identity=28.0769230769231, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=27.4900398406374, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=27.8625954198473, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=26.8774703557312, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=25.968992248062, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=26.4, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=261, Percent_Identity=27.2030651340996, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=269, Percent_Identity=25.2788104089219, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17561272, Length=258, Percent_Identity=27.1317829457364, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21355319, Length=255, Percent_Identity=26.6666666666667, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24639444, Length=260, Percent_Identity=25.7692307692308, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24644339, Length=257, Percent_Identity=25.6809338521401, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=26.0869565217391, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=27.1653543307087, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571526, Length=259, Percent_Identity=27.7992277992278, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26967; Mature: 26967

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGIKGRRALVCASSKGLGRGCAAALAAEGVHVTMTARGAEALAQAAAELRKAYPDVEI
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHCCCCEE
IEVAGDITTPEGRAAALAACPEPDILINNAGGPPPGDFRNWTRDDWIKALDANMLTPIEL
EEECCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHH
IKATVDKMIERKFGRIVNITSAAVKAPIDVLGLSNGARSGLTGFVAGLSRKTVRHNVTIN
HHHHHHHHHHHHHCCEEEHHHHHHHCCHHEEECCCCCCCCHHHHHHHHHHHHEEECEEEE
ALLPGPFDTDRLRGVAAGQAKASGKPAEQILEARKNENPAGRFGTPDEFGAACAFLCSVH
EEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
AGYITGQNLLLDGGAFPGTM
HCEEECCEEEEECCCCCCCC
>Mature Secondary Structure
MDLGIKGRRALVCASSKGLGRGCAAALAAEGVHVTMTARGAEALAQAAAELRKAYPDVEI
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHCCCCEE
IEVAGDITTPEGRAAALAACPEPDILINNAGGPPPGDFRNWTRDDWIKALDANMLTPIEL
EEECCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHH
IKATVDKMIERKFGRIVNITSAAVKAPIDVLGLSNGARSGLTGFVAGLSRKTVRHNVTIN
HHHHHHHHHHHHHCCEEEHHHHHHHCCHHEEECCCCCCCCHHHHHHHHHHHHEEECEEEE
ALLPGPFDTDRLRGVAAGQAKASGKPAEQILEARKNENPAGRFGTPDEFGAACAFLCSVH
EEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
AGYITGQNLLLDGGAFPGTM
HCEEECCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]