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The map label for this gene is mhpC [C]

Identifier: 192290234

GI number: 192290234

Start: 1973949

End: 1974950

Strand: Reverse

Name: mhpC [C]

Synonym: Rpal_1838

Alternate gene names: 192290234

Gene position: 1974950-1973949 (Counterclockwise)

Preceding gene: 192290238

Following gene: 192290233

Centisome position: 34.38

GC content: 70.26

Gene sequence:

>1002_bases
ATGACGACGTTGATCTTGCTGGTGCTGAGCGTCGTCGTGCTGTTCACGGCGGCGGGCTGGGTCTCGTGCCGTCTGGCGCG
CCGGCTGGAGGCGCGCTATCCGCCGCGCGGCGTGTTCATCAATGCCAACGGCGTGCGGATGCACGCGCTCGACTTATCGC
CTGCACGTCCCGCCGCTTCCGGCCAGCCGACCGTCTTGCTGCTGCACGGCGCCAACCTGTGCTGCGAAGATATGCGGATG
TCGCTGGGCGAGCGGCTGGCGCAGCGGCTGCGGGTGATCGTTCCGGACCGCCCCGGCCAGGGCTACAGCGTCACCGGCAC
AGGCCCGGTCGCCTCGCCGGCCTATCAGGTGACGTTGATCCGCGAAGTGCTGCGCGATCGCGACGCCGGCCCGTTGATCG
TGGTCGGGCATTCGTTCGGCGGCCTGATCGCGCTGCGCTATGCGCTCGACAATCCCGACACCGTCGCCGGGCTCGTTCTG
ATCAATCCGACCACCCATCCCCGACCGCAGGGCCTGCCGCTGTTCCAGCGTGCCGCCGAAGTGCTGATGAAGCCGCTGGT
CACCTACACACTGCTGCCGCCGCTGTCGCTGGCGATGATGAAGCGGATCTCGGCGCGGATCTTCCGGCCGGAAACGCCGC
CGGCGGACTATGCCGAGCGCAGCCGGCTGGCGCTGGCGCTGACCGCCAAGCGGTTCGCCGCCAGTCTGGAAGAGTATGCC
GGGCTGCGGGATCAGCTGATCGATCACGTGCCGCGCTATGGCGCCATCCAGGTGCCGACCGTGATCGTCGCCGGCACCGC
CGATCCGGTGGTACCGCCGCAGGTCCACGCCGAAGCGCTGGCGCAGGCGGTGCCGCAGGCCAGGCTGCTGCGACTGAACG
GCGCCGGCCACATGGCGCATCATGCCCACGCCGACACCATCGCAGCCGAGATCGAGCGGCTGGCGGATGCGGTCGCGGAG
CGCGCCGCGCCGTCCCGTGCCGAAGCCGCCGAGCGCAGCTGA

Upstream 100 bases:

>100_bases
GCCATTGCGAAAGATCAATTGCGACCACACGTCCGCGTGCTCAATTTCGGCTGCCGCTGCGGGCTCGACCGCGGCCGATT
CTCTATGGCCGAAGGATACG

Downstream 100 bases:

>100_bases
CGCCAACAACGTCCGCGGCGCGATGAAACCTCAGCGCGTCGGGAACGTTCCTTTTCCGGAACCAACGGAGTGTGTCATGA
CCACGTTCAAGCTGGCCTGT

Product: alpha/beta hydrolase fold protein

Products: 2-oxopent-4-enoate; succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTTLILLVLSVVVLFTAAGWVSCRLARRLEARYPPRGVFINANGVRMHALDLSPARPAASGQPTVLLLHGANLCCEDMRM
SLGERLAQRLRVIVPDRPGQGYSVTGTGPVASPAYQVTLIREVLRDRDAGPLIVVGHSFGGLIALRYALDNPDTVAGLVL
INPTTHPRPQGLPLFQRAAEVLMKPLVTYTLLPPLSLAMMKRISARIFRPETPPADYAERSRLALALTAKRFAASLEEYA
GLRDQLIDHVPRYGAIQVPTVIVAGTADPVVPPQVHAEALAQAVPQARLLRLNGAGHMAHHAHADTIAAEIERLADAVAE
RAAPSRAEAAERS

Sequences:

>Translated_333_residues
MTTLILLVLSVVVLFTAAGWVSCRLARRLEARYPPRGVFINANGVRMHALDLSPARPAASGQPTVLLLHGANLCCEDMRM
SLGERLAQRLRVIVPDRPGQGYSVTGTGPVASPAYQVTLIREVLRDRDAGPLIVVGHSFGGLIALRYALDNPDTVAGLVL
INPTTHPRPQGLPLFQRAAEVLMKPLVTYTLLPPLSLAMMKRISARIFRPETPPADYAERSRLALALTAKRFAASLEEYA
GLRDQLIDHVPRYGAIQVPTVIVAGTADPVVPPQVHAEALAQAVPQARLLRLNGAGHMAHHAHADTIAAEIERLADAVAE
RAAPSRAEAAERS
>Mature_332_residues
TTLILLVLSVVVLFTAAGWVSCRLARRLEARYPPRGVFINANGVRMHALDLSPARPAASGQPTVLLLHGANLCCEDMRMS
LGERLAQRLRVIVPDRPGQGYSVTGTGPVASPAYQVTLIREVLRDRDAGPLIVVGHSFGGLIALRYALDNPDTVAGLVLI
NPTTHPRPQGLPLFQRAAEVLMKPLVTYTLLPPLSLAMMKRISARIFRPETPPADYAERSRLALALTAKRFAASLEEYAG
LRDQLIDHVPRYGAIQVPTVIVAGTADPVVPPQVHAEALAQAVPQARLLRLNGAGHMAHHAHADTIAAEIERLADAVAER
AAPSRAEAAERS

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.7.1.- [C]

Molecular weight: Translated: 35838; Mature: 35707

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLILLVLSVVVLFTAAGWVSCRLARRLEARYPPRGVFINANGVRMHALDLSPARPAAS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEECCCCCCCCC
GQPTVLLLHGANLCCEDMRMSLGERLAQRLRVIVPDRPGQGYSVTGTGPVASPAYQVTLI
CCCEEEEEECCCHHHHHHHHHHHHHHHHHCEEEECCCCCCCEEEECCCCCCCCHHHHHHH
REVLRDRDAGPLIVVGHSFGGLIALRYALDNPDTVAGLVLINPTTHPRPQGLPLFQRAAE
HHHHHCCCCCCEEEEECCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHH
VLMKPLVTYTLLPPLSLAMMKRISARIFRPETPPADYAERSRLALALTAKRFAASLEEYA
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHH
GLRDQLIDHVPRYGAIQVPTVIVAGTADPVVPPQVHAEALAQAVPQARLLRLNGAGHMAH
CHHHHHHHHCCCCCCEECCEEEEECCCCCCCCCHHHHHHHHHHCCHHEEEEECCCCCCHH
HAHADTIAAEIERLADAVAERAAPSRAEAAERS
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
>Mature Secondary Structure 
TTLILLVLSVVVLFTAAGWVSCRLARRLEARYPPRGVFINANGVRMHALDLSPARPAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEECCCCCCCCC
GQPTVLLLHGANLCCEDMRMSLGERLAQRLRVIVPDRPGQGYSVTGTGPVASPAYQVTLI
CCCEEEEEECCCHHHHHHHHHHHHHHHHHCEEEECCCCCCCEEEECCCCCCCCHHHHHHH
REVLRDRDAGPLIVVGHSFGGLIALRYALDNPDTVAGLVLINPTTHPRPQGLPLFQRAAE
HHHHHCCCCCCEEEEECCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHH
VLMKPLVTYTLLPPLSLAMMKRISARIFRPETPPADYAERSRLALALTAKRFAASLEEYA
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHH
GLRDQLIDHVPRYGAIQVPTVIVAGTADPVVPPQVHAEALAQAVPQARLLRLNGAGHMAH
CHHHHHHHHCCCCCCEECCEEEEECCCCCCCCCHHHHHHHHHHCCHHEEEEECCCCCCHH
HAHADTIAAEIERLADAVAERAAPSRAEAAERS
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-hydroxy-6-ketononadienedicarboxylate; H2O [C]

Specific reaction: 2-hydroxy-6-ketononadienedicarboxylate + H2O = 2-oxopent-4-enoate + succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]