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The map label for this gene is cysQ [H]

Identifier: 192290211

GI number: 192290211

Start: 1949016

End: 1949843

Strand: Reverse

Name: cysQ [H]

Synonym: Rpal_1815

Alternate gene names: 192290211

Gene position: 1949843-1949016 (Counterclockwise)

Preceding gene: 192290218

Following gene: 192290209

Centisome position: 33.95

GC content: 70.29

Gene sequence:

>828_bases
ATGACTGCCGCGTTCGAACAGCCCGCCGTCGTTTCGGCCGAGCACGCCGCCGCTTTGCTCGAACCGCTCACCAAGCTGGT
GCTGCGCGCCGGGGCGGCGATCATGGCGATCCCGCGCGACGCCAAGGTCACTCAGAAGCCGGACGGCTCGCCGGTGACGC
CCGCCGATCTCGCCGCTGACCAGGTGATCGCCGAGGGGCTGGCGCAGATCGCTCCGCACGTCCCGGTGCTGTCCGAAGAA
TGTTGCGGCAATGGACGACCGACGTCGGGCAGCTTCTTCGTGGTCGATCCGCTCGACGGCACCAAGGAGTACATCGCCGG
CCGCAACGAATTCACCGTCAACCTGGCGCTGGTGTGCGACGGGGTGCCGGTGCTCGGCATCATCGGCGCGCCGGCTCGAG
GGCTGGCGTGGCGCGGCGTGGTCGGCCATGGCGCTGAGCAACTGACTGTCGCCGCGGACGGGGTCAGCTTTGCAGCCACC
GCCATCCGGACCAGGCCGCTGCCGCAGCCGGGCGAGCCGTGGACCGCAACGGTCAGCCGGTCGCATCTCGATCCCGCCAC
CGTCGCCTTCATCGACGCCCGCCCCAGCGCCGTGCGCACGACGCTGGGTTCGTCGCTGAAATTCTGCTGGATCGCCGAAG
GCAAGGCCGACATCTACCCGCGGCTGGCGCCGATCTGCGAGTGGGATATCGCGGCGGGCGCTGCGCTGGTCATCGCCGCG
GGCGGCAAGGTGACCGACGCGACCGGCGCGCCGTTGCGGTTCGACGCACCGCGGCCGAACTTCATCGTGCCCGAATTCAT
CGCCTGGGGCGACCCTGACGGTCGCTAG

Upstream 100 bases:

>100_bases
AATCAGCCTTGGTTAATGGCTTGATACACTGCGGCTGCAGGCAGTGCCAACACAACGGTCCGGCACAAACCGGACCACCG
ACCGAGGATGACACAGCTTG

Downstream 100 bases:

>100_bases
CGCCGGAGCTATTCGGCGAGCGTTGCCAAGAGTCCCGGCCAGCGCTCGCGGGCGTCATGGAGATAACGCTCCGGATTGGC
CGCGAAGGCATCGCGGTTTT

Product: inositol monophosphatase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MTAAFEQPAVVSAEHAAALLEPLTKLVLRAGAAIMAIPRDAKVTQKPDGSPVTPADLAADQVIAEGLAQIAPHVPVLSEE
CCGNGRPTSGSFFVVDPLDGTKEYIAGRNEFTVNLALVCDGVPVLGIIGAPARGLAWRGVVGHGAEQLTVAADGVSFAAT
AIRTRPLPQPGEPWTATVSRSHLDPATVAFIDARPSAVRTTLGSSLKFCWIAEGKADIYPRLAPICEWDIAAGAALVIAA
GGKVTDATGAPLRFDAPRPNFIVPEFIAWGDPDGR

Sequences:

>Translated_275_residues
MTAAFEQPAVVSAEHAAALLEPLTKLVLRAGAAIMAIPRDAKVTQKPDGSPVTPADLAADQVIAEGLAQIAPHVPVLSEE
CCGNGRPTSGSFFVVDPLDGTKEYIAGRNEFTVNLALVCDGVPVLGIIGAPARGLAWRGVVGHGAEQLTVAADGVSFAAT
AIRTRPLPQPGEPWTATVSRSHLDPATVAFIDARPSAVRTTLGSSLKFCWIAEGKADIYPRLAPICEWDIAAGAALVIAA
GGKVTDATGAPLRFDAPRPNFIVPEFIAWGDPDGR
>Mature_274_residues
TAAFEQPAVVSAEHAAALLEPLTKLVLRAGAAIMAIPRDAKVTQKPDGSPVTPADLAADQVIAEGLAQIAPHVPVLSEEC
CGNGRPTSGSFFVVDPLDGTKEYIAGRNEFTVNLALVCDGVPVLGIIGAPARGLAWRGVVGHGAEQLTVAADGVSFAATA
IRTRPLPQPGEPWTATVSRSHLDPATVAFIDARPSAVRTTLGSSLKFCWIAEGKADIYPRLAPICEWDIAAGAALVIAAG
GKVTDATGAPLRFDAPRPNFIVPEFIAWGDPDGR

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=243, Percent_Identity=26.3374485596708, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1790659, Length=253, Percent_Identity=38.7351778656126, Blast_Score=146, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71995905, Length=170, Percent_Identity=30.5882352941176, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71995897, Length=170, Percent_Identity=30.5882352941176, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI193202572, Length=252, Percent_Identity=23.4126984126984, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324508, Length=194, Percent_Identity=34.5360824742268, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 28497; Mature: 28366

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAFEQPAVVSAEHAAALLEPLTKLVLRAGAAIMAIPRDAKVTQKPDGSPVTPADLAAD
CCCCCCCCCEECHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHH
QVIAEGLAQIAPHVPVLSEECCGNGRPTSGSFFVVDPLDGTKEYIAGRNEFTVNLALVCD
HHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCEEEEECCCCCHHHHCCCCCEEEEEEEEEC
GVPVLGIIGAPARGLAWRGVVGHGAEQLTVAADGVSFAATAIRTRPLPQPGEPWTATVSR
CCCEEEEECCCCCCCEECCHHCCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCEEEEEC
SHLDPATVAFIDARPSAVRTTLGSSLKFCWIAEGKADIYPRLAPICEWDIAAGAALVIAA
CCCCCEEEEEEECCCHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEC
GGKVTDATGAPLRFDAPRPNFIVPEFIAWGDPDGR
CCCEECCCCCCEEECCCCCCEECCHHEECCCCCCC
>Mature Secondary Structure 
TAAFEQPAVVSAEHAAALLEPLTKLVLRAGAAIMAIPRDAKVTQKPDGSPVTPADLAAD
CCCCCCCCEECHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCHHHHHHH
QVIAEGLAQIAPHVPVLSEECCGNGRPTSGSFFVVDPLDGTKEYIAGRNEFTVNLALVCD
HHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCEEEEECCCCCHHHHCCCCCEEEEEEEEEC
GVPVLGIIGAPARGLAWRGVVGHGAEQLTVAADGVSFAATAIRTRPLPQPGEPWTATVSR
CCCEEEEECCCCCCCEECCHHCCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCEEEEEC
SHLDPATVAFIDARPSAVRTTLGSSLKFCWIAEGKADIYPRLAPICEWDIAAGAALVIAA
CCCCCEEEEEEECCCHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEC
GGKVTDATGAPLRFDAPRPNFIVPEFIAWGDPDGR
CCCEECCCCCCEEECCCCCCEECCHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]