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The map label for this gene is mmgC [H]

Identifier: 192290199

GI number: 192290199

Start: 1935944

End: 1937116

Strand: Reverse

Name: mmgC [H]

Synonym: Rpal_1802

Alternate gene names: 192290199

Gene position: 1937116-1935944 (Counterclockwise)

Preceding gene: 192290200

Following gene: 192290198

Centisome position: 33.72

GC content: 64.54

Gene sequence:

>1173_bases
ATGAAACACCATGCCGCGGAGCAGGACGAATACCACGACATCCGCGACGCCGTCGCCAAACTGTGTGCGCAGTTTCCCGG
CGAGTACTGGCGCAAACTCGACCGCGAAATGGCCTATCCCAAGGCGTTCGTCGACGCCCTGACGGAGGCCGGTTACCTTT
CCGTTCTGATCCCCGAGGAATACGGCGGCGCCGGCCTGAAGCTGTCGGCCGCGGCGGCGATCCTGGAAGAGATCCAGCGC
GCCGGCTGCAACGGCGGCGGCTGCCACGCCCAGATGTACACCATGGGCACCCTGCTGCGGCACGGCAGCGACGAGCAGAA
GGCCAAGTGGCTGCCGAAGATCGCCAGCGGTGAACTCCGCCTGCAGGCGTTCGGCGTCACCGAGCCGACCTCGGGCACCG
ACACCACCTCGCTGAAGACCTTCGCCAAGAAGGACGCGAACGGCGACTACGTCGTCAACGGCCAGAAGATCTGGACCAGC
CGGGCGGAATATTCCGACCTGATGATCCTGCTCGCACGCACCACGCCGAAGGATCAGGTGACCAAGAAGACCGAAGGCCT
CTCGGTGTTCCTGGTCGACATGCGGGAAGCGCGCGGCCATGGCCTCGAGATCCGGCCGATCCGCACCATGATGAACCACG
CCACCACCGAAGTGTTCTTCACCGACATGAAGGTGCCGAAGGAGAACCTGATCGGCGAAGAGGGCAAGGGCTTCCGCTAC
ATCCTCTCCGGCATGAATGCCGAGCGCATCCTGATCGCCTCGGAGTGCGTCGGCGACGCCAAATGGTTCATCGCCAAGGC
CAGCGCCTACGCCAAGGACCGCGCGGTGTTCGGCCGGCCGATCGGCCAGAACCAGGGCATCCAGTTCCCGATCGCCAAGG
CCTACGCCAACATGCGCGCCGCCGAGCTGATGGTGAAGGAAGCCACCCGCAAGTACGAAGCCGGCATGGATTGCGGCGCC
GAGGCCAACATGGCCAAGATGCTCGCGGCCGATGCGTCGTTCGAGGCGGCCAATGCCTGCATCCAGACCCACGGCGGCTT
CGGCTTCGCCGAGGAATACGACGTCGAGCGCAAATTCCGAGAAACCCGGCTGTATCAGGTCGCACCGATCTCGACCAACC
TGATCCTGTCGCATCTCGCCGAGCACGTGCTCGGGATGCCGCGGTCGTACTAA

Upstream 100 bases:

>100_bases
GAGCCGAAGCGGGTGTATTCGAGCTTCGTCAAGGGCTACGAGTCCTTGCCGGTCCGGGTCTCATGACCTCCCCCCCAAAA
CCAACAAGAAGACGCAGCCG

Downstream 100 bases:

>100_bases
ACCTCTTCCATCGCGTGCAATGCACCCGGTAACATCAACTCGTCATTCCGGGGCGCCGCGTAGCGGCGAACCCGGAATCC
CGAGCTGTTGATCCGGCATC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MKHHAAEQDEYHDIRDAVAKLCAQFPGEYWRKLDREMAYPKAFVDALTEAGYLSVLIPEEYGGAGLKLSAAAAILEEIQR
AGCNGGGCHAQMYTMGTLLRHGSDEQKAKWLPKIASGELRLQAFGVTEPTSGTDTTSLKTFAKKDANGDYVVNGQKIWTS
RAEYSDLMILLARTTPKDQVTKKTEGLSVFLVDMREARGHGLEIRPIRTMMNHATTEVFFTDMKVPKENLIGEEGKGFRY
ILSGMNAERILIASECVGDAKWFIAKASAYAKDRAVFGRPIGQNQGIQFPIAKAYANMRAAELMVKEATRKYEAGMDCGA
EANMAKMLAADASFEAANACIQTHGGFGFAEEYDVERKFRETRLYQVAPISTNLILSHLAEHVLGMPRSY

Sequences:

>Translated_390_residues
MKHHAAEQDEYHDIRDAVAKLCAQFPGEYWRKLDREMAYPKAFVDALTEAGYLSVLIPEEYGGAGLKLSAAAAILEEIQR
AGCNGGGCHAQMYTMGTLLRHGSDEQKAKWLPKIASGELRLQAFGVTEPTSGTDTTSLKTFAKKDANGDYVVNGQKIWTS
RAEYSDLMILLARTTPKDQVTKKTEGLSVFLVDMREARGHGLEIRPIRTMMNHATTEVFFTDMKVPKENLIGEEGKGFRY
ILSGMNAERILIASECVGDAKWFIAKASAYAKDRAVFGRPIGQNQGIQFPIAKAYANMRAAELMVKEATRKYEAGMDCGA
EANMAKMLAADASFEAANACIQTHGGFGFAEEYDVERKFRETRLYQVAPISTNLILSHLAEHVLGMPRSY
>Mature_390_residues
MKHHAAEQDEYHDIRDAVAKLCAQFPGEYWRKLDREMAYPKAFVDALTEAGYLSVLIPEEYGGAGLKLSAAAAILEEIQR
AGCNGGGCHAQMYTMGTLLRHGSDEQKAKWLPKIASGELRLQAFGVTEPTSGTDTTSLKTFAKKDANGDYVVNGQKIWTS
RAEYSDLMILLARTTPKDQVTKKTEGLSVFLVDMREARGHGLEIRPIRTMMNHATTEVFFTDMKVPKENLIGEEGKGFRY
ILSGMNAERILIASECVGDAKWFIAKASAYAKDRAVFGRPIGQNQGIQFPIAKAYANMRAAELMVKEATRKYEAGMDCGA
EANMAKMLAADASFEAANACIQTHGGFGFAEEYDVERKFRETRLYQVAPISTNLILSHLAEHVLGMPRSY

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=378, Percent_Identity=29.8941798941799, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI4501857, Length=335, Percent_Identity=32.8358208955224, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI4557233, Length=370, Percent_Identity=31.8918918918919, Blast_Score=165, Evalue=7e-41,
Organism=Homo sapiens, GI76496475, Length=344, Percent_Identity=34.3023255813954, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI4557235, Length=335, Percent_Identity=34.0298507462687, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI187960098, Length=339, Percent_Identity=30.6784660766962, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI4557231, Length=339, Percent_Identity=30.6784660766962, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI7656849, Length=344, Percent_Identity=31.6860465116279, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI21361497, Length=386, Percent_Identity=30.0518134715026, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI226958412, Length=366, Percent_Identity=27.8688524590164, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI226958414, Length=359, Percent_Identity=27.5766016713092, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI7669494, Length=333, Percent_Identity=29.7297297297297, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI4503943, Length=333, Percent_Identity=29.7297297297297, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI48976061, Length=327, Percent_Identity=26.605504587156, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI211971008, Length=327, Percent_Identity=26.605504587156, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI38505218, Length=298, Percent_Identity=26.510067114094, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1786223, Length=360, Percent_Identity=29.4444444444444, Blast_Score=148, Evalue=7e-37,
Organism=Escherichia coli, GI87081958, Length=361, Percent_Identity=29.6398891966759, Blast_Score=145, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI71985184, Length=344, Percent_Identity=32.8488372093023, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17506239, Length=372, Percent_Identity=27.9569892473118, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17508101, Length=378, Percent_Identity=28.3068783068783, Blast_Score=165, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17534899, Length=351, Percent_Identity=32.1937321937322, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17570075, Length=368, Percent_Identity=29.0760869565217, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17569725, Length=387, Percent_Identity=27.6485788113695, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71990804, Length=313, Percent_Identity=30.3514376996805, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17538396, Length=375, Percent_Identity=27.2, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71985192, Length=292, Percent_Identity=32.8767123287671, Blast_Score=141, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17505929, Length=364, Percent_Identity=27.7472527472527, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17551932, Length=368, Percent_Identity=25.2717391304348, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17533517, Length=340, Percent_Identity=29.1176470588235, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI32563615, Length=251, Percent_Identity=28.2868525896414, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17534353, Length=304, Percent_Identity=27.3026315789474, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71982178, Length=251, Percent_Identity=28.6852589641434, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17531909, Length=247, Percent_Identity=28.3400809716599, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17562446, Length=310, Percent_Identity=26.4516129032258, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17531913, Length=167, Percent_Identity=27.5449101796407, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI86563381, Length=269, Percent_Identity=26.3940520446097, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI86563383, Length=269, Percent_Identity=26.3940520446097, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356377, Length=341, Percent_Identity=33.4310850439883, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24666513, Length=380, Percent_Identity=31.3157894736842, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24660351, Length=360, Percent_Identity=29.4444444444444, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI281363737, Length=331, Percent_Identity=31.7220543806647, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24646207, Length=372, Percent_Identity=28.494623655914, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI21355753, Length=337, Percent_Identity=29.080118694362, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI19920834, Length=350, Percent_Identity=28.2857142857143, Blast_Score=112, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43106; Mature: 43106

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHHAAEQDEYHDIRDAVAKLCAQFPGEYWRKLDREMAYPKAFVDALTEAGYLSVLIPEE
CCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEECC
YGGAGLKLSAAAAILEEIQRAGCNGGGCHAQMYTMGTLLRHGSDEQKAKWLPKIASGELR
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCEE
LQAFGVTEPTSGTDTTSLKTFAKKDANGDYVVNGQKIWTSRAEYSDLMILLARTTPKDQV
EEEECCCCCCCCCCCHHHHHHHHCCCCCCEEECCCEEECCCCCCCCEEEEEECCCCHHHH
TKKTEGLSVFLVDMREARGHGLEIRPIRTMMNHATTEVFFTDMKVPKENLIGEEGKGFRY
HHHCCCCEEEEEEEHHHCCCCEEEHHHHHHHHHHHHEEEEECCCCCHHHCCCCCCCCHHH
ILSGMNAERILIASECVGDAKWFIAKASAYAKDRAVFGRPIGQNQGIQFPIAKAYANMRA
HCCCCCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
AELMVKEATRKYEAGMDCGAEANMAKMLAADASFEAANACIQTHGGFGFAEEYDVERKFR
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
ETRLYQVAPISTNLILSHLAEHVLGMPRSY
HHHCEEEECCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKHHAAEQDEYHDIRDAVAKLCAQFPGEYWRKLDREMAYPKAFVDALTEAGYLSVLIPEE
CCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEECC
YGGAGLKLSAAAAILEEIQRAGCNGGGCHAQMYTMGTLLRHGSDEQKAKWLPKIASGELR
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCEE
LQAFGVTEPTSGTDTTSLKTFAKKDANGDYVVNGQKIWTSRAEYSDLMILLARTTPKDQV
EEEECCCCCCCCCCCHHHHHHHHCCCCCCEEECCCEEECCCCCCCCEEEEEECCCCHHHH
TKKTEGLSVFLVDMREARGHGLEIRPIRTMMNHATTEVFFTDMKVPKENLIGEEGKGFRY
HHHCCCCEEEEEEEHHHCCCCEEEHHHHHHHHHHHHEEEEECCCCCHHHCCCCCCCCHHH
ILSGMNAERILIASECVGDAKWFIAKASAYAKDRAVFGRPIGQNQGIQFPIAKAYANMRA
HCCCCCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
AELMVKEATRKYEAGMDCGAEANMAKMLAADASFEAANACIQTHGGFGFAEEYDVERKFR
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
ETRLYQVAPISTNLILSHLAEHVLGMPRSY
HHHCEEEECCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]