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The map label for this gene is mauR [H]

Identifier: 192290148

GI number: 192290148

Start: 1878106

End: 1879080

Strand: Reverse

Name: mauR [H]

Synonym: Rpal_1750

Alternate gene names: 192290148

Gene position: 1879080-1878106 (Counterclockwise)

Preceding gene: 192290154

Following gene: 192290141

Centisome position: 32.71

GC content: 61.74

Gene sequence:

>975_bases
ATGACAGAGTTCAATTCACTCGACTGGGACGACCTGAAGGTGTTCCTGCATGCGGCCCGCGGCGGCAGCCTGGGCAGCGC
GGCGCGACGACTGAAGGTCGACCAATCCACCATCAGTCGGAAGATCGCCCATCTCGAAAGCACTCTCGGGATCGCACTGT
TCGAGCGGCTTCCCTCCGGACTACGCGTGACCGAGCTCGGCGACCGACTGCTCTGCCATGCCGAACGGATCGAGAGCGCC
GTGATCGCGATGCGCGAGGACGTGCAATGCAGCGGTGGCCGAACGGCGGGCCGCGTCCGGCTGGCGACAATGGAAGGGAT
CGCGTCGTTGTATCTGGCCGCTCAGTTCTCGCGGCTGCACCGCCAACATCCAAATCTGATCGTGGAGTTGCTGACGTCGC
CGCAAGCCGTCTCGGTCAACCGCCGCGAGGCCGACCTCTTCCTCAGCTTCTTTCAACCCCGCGGCCAGGGCATGGTCTCG
GAACGCATCGGTTGCTTCGAACTCGGACTGTACGCATCAGAGGACTACATCGCGCAAAACGGCTTGCCCTGCTCTTCCGC
TGATCTTAAGCGACACCGTTTCATCACCTATATCGACGACCTCATCCAGCTCGATTCGGTACGCTGGCTCGACGACGTCA
TCAAAACCCCCGTGGTGAGTTTTCATTCCAACAGCATGATCGCGCAGATGAACGCCGCCGCTGGCGGGCTCGGGCTGGTG
CTATTGCCGAGCTTCGCCACCAAGGGCCGCTGCGATCTGATACCAGTTCTCCACGATCGGATGTCGACGTCGCGCGAATT
GTGGATCAACGTGCATACCGACCTGCAATTCGTGCCGCGCATCCGCGCGGTGTCGAGCTTCCTGAAGGCGACCTTCAAGG
CCGATCAGATGATGCAGGTCGATACCTCGGGGAAAAAGATGTTGAACGCGCTCCTCGACACCGAGCCGGCGGTCTCCGCG
GTCCGCGGCCATTGA

Upstream 100 bases:

>100_bases
CCGCGGACGATGGGTAGAGGCAATCCTGCAACCCGGCTTGCAGTCGGCGACACTTCGCCTCCCCGGCTCCGATTGGCACA
GCTTTTGCCGATACGAAGCC

Downstream 100 bases:

>100_bases
CCGGGATGCGCCCGCGGGACCAAGACGAGCATCAGCGTGACGTGGCGCGACCGATGCTCACCGGTCGCGACCGTCTTCCT
TCCCGAACACCCGGCTCGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTEFNSLDWDDLKVFLHAARGGSLGSAARRLKVDQSTISRKIAHLESTLGIALFERLPSGLRVTELGDRLLCHAERIESA
VIAMREDVQCSGGRTAGRVRLATMEGIASLYLAAQFSRLHRQHPNLIVELLTSPQAVSVNRREADLFLSFFQPRGQGMVS
ERIGCFELGLYASEDYIAQNGLPCSSADLKRHRFITYIDDLIQLDSVRWLDDVIKTPVVSFHSNSMIAQMNAAAGGLGLV
LLPSFATKGRCDLIPVLHDRMSTSRELWINVHTDLQFVPRIRAVSSFLKATFKADQMMQVDTSGKKMLNALLDTEPAVSA
VRGH

Sequences:

>Translated_324_residues
MTEFNSLDWDDLKVFLHAARGGSLGSAARRLKVDQSTISRKIAHLESTLGIALFERLPSGLRVTELGDRLLCHAERIESA
VIAMREDVQCSGGRTAGRVRLATMEGIASLYLAAQFSRLHRQHPNLIVELLTSPQAVSVNRREADLFLSFFQPRGQGMVS
ERIGCFELGLYASEDYIAQNGLPCSSADLKRHRFITYIDDLIQLDSVRWLDDVIKTPVVSFHSNSMIAQMNAAAGGLGLV
LLPSFATKGRCDLIPVLHDRMSTSRELWINVHTDLQFVPRIRAVSSFLKATFKADQMMQVDTSGKKMLNALLDTEPAVSA
VRGH
>Mature_323_residues
TEFNSLDWDDLKVFLHAARGGSLGSAARRLKVDQSTISRKIAHLESTLGIALFERLPSGLRVTELGDRLLCHAERIESAV
IAMREDVQCSGGRTAGRVRLATMEGIASLYLAAQFSRLHRQHPNLIVELLTSPQAVSVNRREADLFLSFFQPRGQGMVSE
RIGCFELGLYASEDYIAQNGLPCSSADLKRHRFITYIDDLIQLDSVRWLDDVIKTPVVSFHSNSMIAQMNAAAGGLGLVL
LPSFATKGRCDLIPVLHDRMSTSRELWINVHTDLQFVPRIRAVSSFLKATFKADQMMQVDTSGKKMLNALLDTEPAVSAV
RGH

Specific function: Transcriptional activator of the mau genes involved in methylamine metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=137, Percent_Identity=29.9270072992701, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789639, Length=186, Percent_Identity=25.2688172043011, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI48994962, Length=180, Percent_Identity=29.4444444444444, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790208, Length=146, Percent_Identity=30.1369863013699, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35893; Mature: 35762

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFNSLDWDDLKVFLHAARGGSLGSAARRLKVDQSTISRKIAHLESTLGIALFERLPSG
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC
LRVTELGDRLLCHAERIESAVIAMREDVQCSGGRTAGRVRLATMEGIASLYLAAQFSRLH
CEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
RQHPNLIVELLTSPQAVSVNRREADLFLSFFQPRGQGMVSERIGCFELGLYASEDYIAQN
HHCCHHHHHHHCCCCEEECCCHHHHHHHHHHCCCCCCHHHHCCCCEEECCCCCCCHHHCC
GLPCSSADLKRHRFITYIDDLIQLDSVRWLDDVIKTPVVSFHSNSMIAQMNAAAGGLGLV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEECCCCCCCEEE
LLPSFATKGRCDLIPVLHDRMSTSRELWINVHTDLQFVPRIRAVSSFLKATFKADQMMQV
EECCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHEEEE
DTSGKKMLNALLDTEPAVSAVRGH
CCCHHHHHHHHHCCCHHHHHHCCC
>Mature Secondary Structure 
TEFNSLDWDDLKVFLHAARGGSLGSAARRLKVDQSTISRKIAHLESTLGIALFERLPSG
CCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC
LRVTELGDRLLCHAERIESAVIAMREDVQCSGGRTAGRVRLATMEGIASLYLAAQFSRLH
CEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
RQHPNLIVELLTSPQAVSVNRREADLFLSFFQPRGQGMVSERIGCFELGLYASEDYIAQN
HHCCHHHHHHHCCCCEEECCCHHHHHHHHHHCCCCCCHHHHCCCCEEECCCCCCCHHHCC
GLPCSSADLKRHRFITYIDDLIQLDSVRWLDDVIKTPVVSFHSNSMIAQMNAAAGGLGLV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEECCCCCCCEEE
LLPSFATKGRCDLIPVLHDRMSTSRELWINVHTDLQFVPRIRAVSSFLKATFKADQMMQV
EECCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHEEEE
DTSGKKMLNALLDTEPAVSAVRGH
CCCHHHHHHHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7957249 [H]