Click here to switch to the map view.

The map label for this gene is yciC [H]

Identifier: 192290046

GI number: 192290046

Start: 1763992

End: 1765200

Strand: Reverse

Name: yciC [H]

Synonym: Rpal_1647

Alternate gene names: 192290046

Gene position: 1765200-1763992 (Counterclockwise)

Preceding gene: 192290048

Following gene: 192290045

Centisome position: 30.73

GC content: 64.6

Gene sequence:

>1209_bases
ATGGATCACCCCCTTCTCCCGGTCACCGTTCTGTCCGGCTTTCTCGGCGCCGGCAAAACCACCCTTCTCAACCGGATGCT
GTCCAACCGTGAAGGCCGGCGGCTGGCGGTGATCGTCAATGACATGAGCGAGGTGAACATTGACGCCGAGCTGGTGCGCC
AGGATGGCGGGTTGACGCGGTCGGAGGAAACATTGGTCGAGATGACCAATGGCTGCATCTGCTGCACGCTGCGTGAGGAC
CTGCTGCTCGAAGTCCGCAAGCTCGCCGAGAGCGGCCGGTTCGACGGGTTGGTGATCGAATCCACCGGCATCGCTGAGCC
GCTGCCGATCGCCGCGACGTTCGAATTCCGCGACGAGAACGGCGCCAGTCTGTCCGACATCGCGCGGCTCGACACCATGG
TGACGGTGGTCGATACGGCCAGCCTGCTGGCGAACTACTCCAGCCAGGAATTCCTGCGCGACCGCGGCGAAGTCGCCGGC
GCCGACGACGAGCGGACACTGGTCGATCTGCTGGTCGAACAGATCGAATTCGCCGACGTCATCGTGCTCAACAAGGTGTC
GGCGACCTCGCCGAGCCGGCGCGAAACCGCGCGGTCGATCGTGCGAGCGCTGAACTCGGATGCCAGGATCATCGAAGCCG
ATTTCGGCGACGTACCTCTGTCGTCGGTCTTGCACACCGGACTGTTCGATTTCGAGCGCGCGCATCAGCACCCGCTGTGG
TTCAAGGAACTAAACGGCTTCGCCGACCACGTGCCGGAAACCGAAGAATACGGCATCCGCTCATTCGTGTACCGGGCGCG
GCGGCCGTTTCATCCGCTCCGCTTCCAGTCGTTCTGCAACCGGAGCTGGCCGGGCGTAATCCGCGCCAAGGGCTTCTTCT
GGCTGGCGACGCGACCGCAGCATGTCGGTGAAATCGCGCAGGCCGGCGCGATGGTACGCACCTCCAAGCGCGGACTGTGG
TGGTCGGCGGTGCCGAAGACGCGCTGGCCCGACAACGCCGACTGGCACGAGGCGATGAAGCCGTATTTCGATCCGGTGTG
GGGCGACCGCCGCCAGGAAATCGTGTTCATCGGCACCGGCGAGATGGACGAAGCCGCGCTGCGCCGCCAGCTCGATCTCT
GTCTCGTCGGTGAAGATGCGCAGTTCACGCCGGATGCGTGGCAGCAATTGCCCGATCCGTTCCCGAGCTGGGCGCCGGCA
CAGAACTGA

Upstream 100 bases:

>100_bases
TCCGCTCCGGCTTGAGCTCGGAGGCTTGCCCGGCCTTTATGTAATGTTATAACGTTTCATACGCAATCCTCCAATACCTG
CAATCGAAGGCCCTTCCGCC

Downstream 100 bases:

>100_bases
ACCCAATTATTGACCCGCCCCAATGATCCGGTTGTGTGCTCTGGCACAATCGGATCAAGTGCCGCGGCGCGTTCGCGGCA
GAGCTTCGGCGTTGGGGGAT

Product: cobalamin synthesis protein P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MDHPLLPVTVLSGFLGAGKTTLLNRMLSNREGRRLAVIVNDMSEVNIDAELVRQDGGLTRSEETLVEMTNGCICCTLRED
LLLEVRKLAESGRFDGLVIESTGIAEPLPIAATFEFRDENGASLSDIARLDTMVTVVDTASLLANYSSQEFLRDRGEVAG
ADDERTLVDLLVEQIEFADVIVLNKVSATSPSRRETARSIVRALNSDARIIEADFGDVPLSSVLHTGLFDFERAHQHPLW
FKELNGFADHVPETEEYGIRSFVYRARRPFHPLRFQSFCNRSWPGVIRAKGFFWLATRPQHVGEIAQAGAMVRTSKRGLW
WSAVPKTRWPDNADWHEAMKPYFDPVWGDRRQEIVFIGTGEMDEAALRRQLDLCLVGEDAQFTPDAWQQLPDPFPSWAPA
QN

Sequences:

>Translated_402_residues
MDHPLLPVTVLSGFLGAGKTTLLNRMLSNREGRRLAVIVNDMSEVNIDAELVRQDGGLTRSEETLVEMTNGCICCTLRED
LLLEVRKLAESGRFDGLVIESTGIAEPLPIAATFEFRDENGASLSDIARLDTMVTVVDTASLLANYSSQEFLRDRGEVAG
ADDERTLVDLLVEQIEFADVIVLNKVSATSPSRRETARSIVRALNSDARIIEADFGDVPLSSVLHTGLFDFERAHQHPLW
FKELNGFADHVPETEEYGIRSFVYRARRPFHPLRFQSFCNRSWPGVIRAKGFFWLATRPQHVGEIAQAGAMVRTSKRGLW
WSAVPKTRWPDNADWHEAMKPYFDPVWGDRRQEIVFIGTGEMDEAALRRQLDLCLVGEDAQFTPDAWQQLPDPFPSWAPA
QN
>Mature_402_residues
MDHPLLPVTVLSGFLGAGKTTLLNRMLSNREGRRLAVIVNDMSEVNIDAELVRQDGGLTRSEETLVEMTNGCICCTLRED
LLLEVRKLAESGRFDGLVIESTGIAEPLPIAATFEFRDENGASLSDIARLDTMVTVVDTASLLANYSSQEFLRDRGEVAG
ADDERTLVDLLVEQIEFADVIVLNKVSATSPSRRETARSIVRALNSDARIIEADFGDVPLSSVLHTGLFDFERAHQHPLW
FKELNGFADHVPETEEYGIRSFVYRARRPFHPLRFQSFCNRSWPGVIRAKGFFWLATRPQHVGEIAQAGAMVRTSKRGLW
WSAVPKTRWPDNADWHEAMKPYFDPVWGDRRQEIVFIGTGEMDEAALRRQLDLCLVGEDAQFTPDAWQQLPDPFPSWAPA
QN

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI148727351, Length=314, Percent_Identity=28.6624203821656, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI146231952, Length=314, Percent_Identity=28.6624203821656, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI33469141, Length=314, Percent_Identity=28.6624203821656, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI126722884, Length=314, Percent_Identity=28.6624203821656, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI223941779, Length=210, Percent_Identity=31.4285714285714, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI223941776, Length=304, Percent_Identity=27.9605263157895, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI119120938, Length=147, Percent_Identity=36.0544217687075, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI87082430, Length=366, Percent_Identity=26.2295081967213, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1788499, Length=213, Percent_Identity=27.2300469483568, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324356, Length=234, Percent_Identity=27.3504273504274, Blast_Score=97, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 45201; Mature: 45201

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHPLLPVTVLSGFLGAGKTTLLNRMLSNREGRRLAVIVNDMSEVNIDAELVRQDGGLTR
CCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECHHHCCCCHHHHHCCCCCCC
SEETLVEMTNGCICCTLREDLLLEVRKLAESGRFDGLVIESTGIAEPLPIAATFEFRDEN
CHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEEEEECCC
GASLSDIARLDTMVTVVDTASLLANYSSQEFLRDRGEVAGADDERTLVDLLVEQIEFADV
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHE
IVLNKVSATSPSRRETARSIVRALNSDARIIEADFGDVPLSSVLHTGLFDFERAHQHPLW
EEEECCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCH
FKELNGFADHVPETEEYGIRSFVYRARRPFHPLRFQSFCNRSWPGVIRAKGFFWLATRPQ
HHHHCCHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEECCEEEEECCCH
HVGEIAQAGAMVRTSKRGLWWSAVPKTRWPDNADWHEAMKPYFDPVWGDRRQEIVFIGTG
HHHHHHHCCHHEEECCCCCEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEECC
EMDEAALRRQLDLCLVGEDAQFTPDAWQQLPDPFPSWAPAQN
CHHHHHHHHHCCEEEECCCCCCCCHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDHPLLPVTVLSGFLGAGKTTLLNRMLSNREGRRLAVIVNDMSEVNIDAELVRQDGGLTR
CCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECHHHCCCCHHHHHCCCCCCC
SEETLVEMTNGCICCTLREDLLLEVRKLAESGRFDGLVIESTGIAEPLPIAATFEFRDEN
CHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEEEEECCC
GASLSDIARLDTMVTVVDTASLLANYSSQEFLRDRGEVAGADDERTLVDLLVEQIEFADV
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHE
IVLNKVSATSPSRRETARSIVRALNSDARIIEADFGDVPLSSVLHTGLFDFERAHQHPLW
EEEECCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCH
FKELNGFADHVPETEEYGIRSFVYRARRPFHPLRFQSFCNRSWPGVIRAKGFFWLATRPQ
HHHHCCHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEECCEEEEECCCH
HVGEIAQAGAMVRTSKRGLWWSAVPKTRWPDNADWHEAMKPYFDPVWGDRRQEIVFIGTG
HHHHHHHCCHHEEECCCCCEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEECC
EMDEAALRRQLDLCLVGEDAQFTPDAWQQLPDPFPSWAPAQN
CHHHHHHHHHCCEEEECCCCCCCCHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]