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The map label for this gene is pcaR [H]

Identifier: 192289995

GI number: 192289995

Start: 1707827

End: 1708765

Strand: Reverse

Name: pcaR [H]

Synonym: Rpal_1596

Alternate gene names: 192289995

Gene position: 1708765-1707827 (Counterclockwise)

Preceding gene: 192290002

Following gene: 192289993

Centisome position: 29.75

GC content: 68.8

Gene sequence:

>939_bases
ATGGCGGCGAAGACAACCACGCGCGGGCCCGCGGCCGCCAAGCGACGCGGTGGAGCGAAAACCGCGAAGCGATCTCCTGC
AGCGAGCTCGGAAGATCGCGCGCAACGCCGCGCCGAGCGGCAATCGCTGCAGCGCGCATCGCGCCGGCCCCGCGTCGACG
CCGCCGAACGCGATGATGCCGGCGGCCGGCTGTTCGTCTCGGCGCTGGCGCGCGGCCTCGACGTGCTCGGGGCATTTCGC
GCCGGCGACCGCGCGCTCGGCAATCAGGAGCTCGCCGAGCGCACCGGCCTCCCGAAGCCGACGATCTCGCGGATGACCCA
CACGCTGATCCAGCTCGGCTATCTCACCTACGAGCCACGATCGGCGACCTATCAGCTCGGCGCCCGCGCGCTGGCGCTGA
GCTACGCGGCGCTCGCCAATCTCGACGTCCGCAAAGCCGCGCTGCCGATCATGACGAGGCTCGCCGAAGACAGCCAGCTG
CATGTCGGGCTCGGCACCCGCGAACGGCTGATGATGCTGAACATCGAAAGCTGCGAGAGCGACGCGCTGATCGGCCTGCG
GCTGCCACCGGGCTCGCGCGTGCCGCTCGCCACGACGTCGCTCGGCAAGGCCTATCTGGCGATGATCGGGGACGACGAGC
GCCGGGCGCTGCTGGCGGAATTGCGCGAGCATCATGGCTCAGACTGGCCAAAGATCGAAAAATCGATCACCAAATCGATG
CGCGAGATGGCCAGGCAGGGCTTCTGCATCTCGACCGGCGAGTGGCGCAAGGACATCAACGCAGTCGGCGCCGCAATCGT
GCCGCCGAATGGCGGCCCGGTATATGCTTTGAGCTTCGGCGGCCCGGCCTATCTGGTGTCGCAGCAGCAGCTGATCGAAC
ACCACGGCCCAGCGCTGGCACATGCAGCGAGAGCAATCAGCGCCGCGCTGGGCGGGTAA

Upstream 100 bases:

>100_bases
TTTTGTGCAGCTTGCCACCGCAGCGGCGGTCGCACAATATGCGAAATCGATTTTCGCAAACATCTTTGACCCGCGGCCGC
GCCGCACGGAAACCACGATC

Downstream 100 bases:

>100_bases
CGGCGCGCTCCGTCGTCCTTACGCACGGTAGAGGCACGCCCCCCGTCATTGCGAGCGAAGCGATGCAATCCATCGTCCGG
CGCACGCAGCTGGATTGCTT

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MAAKTTTRGPAAAKRRGGAKTAKRSPAASSEDRAQRRAERQSLQRASRRPRVDAAERDDAGGRLFVSALARGLDVLGAFR
AGDRALGNQELAERTGLPKPTISRMTHTLIQLGYLTYEPRSATYQLGARALALSYAALANLDVRKAALPIMTRLAEDSQL
HVGLGTRERLMMLNIESCESDALIGLRLPPGSRVPLATTSLGKAYLAMIGDDERRALLAELREHHGSDWPKIEKSITKSM
REMARQGFCISTGEWRKDINAVGAAIVPPNGGPVYALSFGGPAYLVSQQQLIEHHGPALAHAARAISAALGG

Sequences:

>Translated_312_residues
MAAKTTTRGPAAAKRRGGAKTAKRSPAASSEDRAQRRAERQSLQRASRRPRVDAAERDDAGGRLFVSALARGLDVLGAFR
AGDRALGNQELAERTGLPKPTISRMTHTLIQLGYLTYEPRSATYQLGARALALSYAALANLDVRKAALPIMTRLAEDSQL
HVGLGTRERLMMLNIESCESDALIGLRLPPGSRVPLATTSLGKAYLAMIGDDERRALLAELREHHGSDWPKIEKSITKSM
REMARQGFCISTGEWRKDINAVGAAIVPPNGGPVYALSFGGPAYLVSQQQLIEHHGPALAHAARAISAALGG
>Mature_311_residues
AAKTTTRGPAAAKRRGGAKTAKRSPAASSEDRAQRRAERQSLQRASRRPRVDAAERDDAGGRLFVSALARGLDVLGAFRA
GDRALGNQELAERTGLPKPTISRMTHTLIQLGYLTYEPRSATYQLGARALALSYAALANLDVRKAALPIMTRLAEDSQLH
VGLGTRERLMMLNIESCESDALIGLRLPPGSRVPLATTSLGKAYLAMIGDDERRALLAELREHHGSDWPKIEKSITKSMR
EMARQGFCISTGEWRKDINAVGAAIVPPNGGPVYALSFGGPAYLVSQQQLIEHHGPALAHAARAISAALGG

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=251, Percent_Identity=27.4900398406374, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87082359, Length=252, Percent_Identity=22.6190476190476, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786715, Length=249, Percent_Identity=24.4979919678715, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 33474; Mature: 33343

Theoretical pI: Translated: 10.80; Mature: 10.80

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAKTTTRGPAAAKRRGGAKTAKRSPAASSEDRAQRRAERQSLQRASRRPRVDAAERDDA
CCCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GGRLFVSALARGLDVLGAFRAGDRALGNQELAERTGLPKPTISRMTHTLIQLGYLTYEPR
CCHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHEECCC
SATYQLGARALALSYAALANLDVRKAALPIMTRLAEDSQLHVGLGTRERLMMLNIESCES
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEECCCCC
DALIGLRLPPGSRVPLATTSLGKAYLAMIGDDERRALLAELREHHGSDWPKIEKSITKSM
CCEEEEECCCCCCCCEEHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHH
REMARQGFCISTGEWRKDINAVGAAIVPPNGGPVYALSFGGPAYLVSQQQLIEHHGPALA
HHHHHCCCCCCCCHHHHHHHHCCCEEECCCCCCEEEEECCCCEEHHHHHHHHHHCCHHHH
HAARAISAALGG
HHHHHHHHHHCC
>Mature Secondary Structure 
AAKTTTRGPAAAKRRGGAKTAKRSPAASSEDRAQRRAERQSLQRASRRPRVDAAERDDA
CCCCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GGRLFVSALARGLDVLGAFRAGDRALGNQELAERTGLPKPTISRMTHTLIQLGYLTYEPR
CCHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHEECCC
SATYQLGARALALSYAALANLDVRKAALPIMTRLAEDSQLHVGLGTRERLMMLNIESCES
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEECCCCC
DALIGLRLPPGSRVPLATTSLGKAYLAMIGDDERRALLAELREHHGSDWPKIEKSITKSM
CCEEEEECCCCCCCCEEHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHH
REMARQGFCISTGEWRKDINAVGAAIVPPNGGPVYALSFGGPAYLVSQQQLIEHHGPALA
HHHHHCCCCCCCCHHHHHHHHCCCEEECCCCCCEEEEECCCCEEHHHHHHHHHHCCHHHH
HAARAISAALGG
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]