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The map label for this gene is yiaY [H]

Identifier: 192289808

GI number: 192289808

Start: 1470990

End: 1472141

Strand: Reverse

Name: yiaY [H]

Synonym: Rpal_1398

Alternate gene names: 192289808

Gene position: 1472141-1470990 (Counterclockwise)

Preceding gene: 192289809

Following gene: 192289806

Centisome position: 25.63

GC content: 65.54

Gene sequence:

>1152_bases
ATGACCGCAACGACCTTCTTCATTCCCTCTCTCAATCTGTTCGGCGCCGGCTGCGTATCGAGCGCAGCGGACCACGCCAA
GGCACGCGGCTTCAAGCGCGCGCTGATCGTCACCGACAGCGGGCTGCACAAGCTCGGCGTCGCCGATCAGATCGCCTCGA
TGCTGATCGAGCGCAACGTGACCAGCGTCGTCTTCCCGGGCGCGAAGCCAAACCCGACGATCAAGAACGTCGAGGACGGG
CTTGCACTGCTGAAGCAGGAACACTGCGACTGTGTGATCTCGCTCGGCGGCGGTTCAGCGCACGACTGCGCGAAGGGCAT
CGCGCTGACCGCCACCAATGGCGGCAGCATCAAGGACTATGAAGGCGTCGATCGGTCGGCGCACGCTCAGCTTCCGCTGA
TCGCCATCAACACCACGGCCGGTACGGCGAGTGAGATGACGCGGTTCTGCATCATCACCGACGAGGAACGCCAGGTGAAG
ATGGCGATCGTCGACCGCCACACCACGCCGCTGCTGTCGGTCAACGATCCGGTACTGATGCTCGGCAAGCCGCCGGCCCT
CACCGCCGCGACCGGCATGGACGCGCTGACGCACGCGATCGAAGCCTATGTGTCGATTGCCGCAACGCCGATCACTGACG
CCTGCGCGCTGAAGGCGATGTCGATCATCTCCAACAGTCTGCGCACCGTGGTCGCCGAGGGCCAGAACCTCGTCGCCCGC
GAGGCGATGTCGTATGCGGGCTTCCTCGCCGGCATGGCGTTCAACAATGCCTCGCTCGGCTATGTACATGCGATGGCGCA
CCAGCTCGGCGGCTTCTACGACCTGCCGCACGGCGTCTGCAACGCGGTGCTGCTGCCGCACGTGCAGGCCTACAACGCGC
AAGTCGCGGCGGGACGGCTGAAGGACGTCGCACACGCGCTCGGCGTCGACACCACCGGCATGACCGATGCCCAGGGCGCC
GATGCCGCCATTCATGCCATCCAGCGGCTATCGGCCGATGTCGGCATTCCGCCCGGTCTCGGCGGTCTCGGCATGAAGGA
AACCGACGTGCCGATCCTCGCCGCCAACGCGCTGAAGGATGCGTGCGGCTTCACCAATCCGAAGCAGGCGACGCAGACCG
AGATCGAAACCATCTTCCGGGCGGCCGCCTGA

Upstream 100 bases:

>100_bases
TGCCCTGGAAACGCGGAGCGTAGCTGGACCGGCGCATTCGTCCGGCCGGAGCGCTCATCGACCACCGATCGACAACGAAA
ACGCATGGAAGGAAACACCA

Downstream 100 bases:

>100_bases
CGGTGGTCGCGTCCATGATCGGGTAGCGGCAGATCCGATCAACCTTGGAGCGGGATGACTTCTGAACTGGCAAGTCATCC
CGCTCGAACTGATCCGGACG

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MTATTFFIPSLNLFGAGCVSSAADHAKARGFKRALIVTDSGLHKLGVADQIASMLIERNVTSVVFPGAKPNPTIKNVEDG
LALLKQEHCDCVISLGGGSAHDCAKGIALTATNGGSIKDYEGVDRSAHAQLPLIAINTTAGTASEMTRFCIITDEERQVK
MAIVDRHTTPLLSVNDPVLMLGKPPALTAATGMDALTHAIEAYVSIAATPITDACALKAMSIISNSLRTVVAEGQNLVAR
EAMSYAGFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQAYNAQVAAGRLKDVAHALGVDTTGMTDAQGA
DAAIHAIQRLSADVGIPPGLGGLGMKETDVPILAANALKDACGFTNPKQATQTEIETIFRAAA

Sequences:

>Translated_383_residues
MTATTFFIPSLNLFGAGCVSSAADHAKARGFKRALIVTDSGLHKLGVADQIASMLIERNVTSVVFPGAKPNPTIKNVEDG
LALLKQEHCDCVISLGGGSAHDCAKGIALTATNGGSIKDYEGVDRSAHAQLPLIAINTTAGTASEMTRFCIITDEERQVK
MAIVDRHTTPLLSVNDPVLMLGKPPALTAATGMDALTHAIEAYVSIAATPITDACALKAMSIISNSLRTVVAEGQNLVAR
EAMSYAGFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQAYNAQVAAGRLKDVAHALGVDTTGMTDAQGA
DAAIHAIQRLSADVGIPPGLGGLGMKETDVPILAANALKDACGFTNPKQATQTEIETIFRAAA
>Mature_382_residues
TATTFFIPSLNLFGAGCVSSAADHAKARGFKRALIVTDSGLHKLGVADQIASMLIERNVTSVVFPGAKPNPTIKNVEDGL
ALLKQEHCDCVISLGGGSAHDCAKGIALTATNGGSIKDYEGVDRSAHAQLPLIAINTTAGTASEMTRFCIITDEERQVKM
AIVDRHTTPLLSVNDPVLMLGKPPALTAATGMDALTHAIEAYVSIAATPITDACALKAMSIISNSLRTVVAEGQNLVARE
AMSYAGFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQAYNAQVAAGRLKDVAHALGVDTTGMTDAQGAD
AAIHAIQRLSADVGIPPGLGGLGMKETDVPILAANALKDACGFTNPKQATQTEIETIFRAAA

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=408, Percent_Identity=25.4901960784314, Blast_Score=116, Evalue=4e-26,
Organism=Escherichia coli, GI48994951, Length=382, Percent_Identity=68.3246073298429, Blast_Score=531, Evalue=1e-152,
Organism=Escherichia coli, GI1789163, Length=384, Percent_Identity=41.1458333333333, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI87082107, Length=378, Percent_Identity=38.6243386243386, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI1787493, Length=405, Percent_Identity=33.8271604938272, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1789386, Length=366, Percent_Identity=25.1366120218579, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17537053, Length=411, Percent_Identity=25.5474452554745, Blast_Score=117, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6321181, Length=383, Percent_Identity=53.5248041775457, Blast_Score=409, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24657991, Length=408, Percent_Identity=23.7745098039216, Blast_Score=105, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 39681; Mature: 39550

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATTFFIPSLNLFGAGCVSSAADHAKARGFKRALIVTDSGLHKLGVADQIASMLIERNV
CCCEEEEECCCHHHCCHHHHHHHHHHHHCCCEEEEEEECCCCHHCCHHHHHHHHHHHCCC
TSVVFPGAKPNPTIKNVEDGLALLKQEHCDCVISLGGGSAHDCAKGIALTATNGGSIKDY
CEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHCCEEEEECCCCCCCCC
EGVDRSAHAQLPLIAINTTAGTASEMTRFCIITDEERQVKMAIVDRHTTPLLSVNDPVLM
CCCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEECCCCCEEECCCCEEE
LGKPPALTAATGMDALTHAIEAYVSIAATPITDACALKAMSIISNSLRTVVAEGQNLVAR
ECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
EAMSYAGFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQAYNAQVAAGRL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHCCCHHHHHHH
KDVAHALGVDTTGMTDAQGADAAIHAIQRLSADVGIPPGLGGLGMKETDVPILAANALKD
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEHHHHHH
ACGFTNPKQATQTEIETIFRAAA
HHCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TATTFFIPSLNLFGAGCVSSAADHAKARGFKRALIVTDSGLHKLGVADQIASMLIERNV
CCEEEEECCCHHHCCHHHHHHHHHHHHCCCEEEEEEECCCCHHCCHHHHHHHHHHHCCC
TSVVFPGAKPNPTIKNVEDGLALLKQEHCDCVISLGGGSAHDCAKGIALTATNGGSIKDY
CEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHCCEEEEECCCCCCCCC
EGVDRSAHAQLPLIAINTTAGTASEMTRFCIITDEERQVKMAIVDRHTTPLLSVNDPVLM
CCCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEECCCCCEEECCCCEEE
LGKPPALTAATGMDALTHAIEAYVSIAATPITDACALKAMSIISNSLRTVVAEGQNLVAR
ECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
EAMSYAGFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQAYNAQVAAGRL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHCCCHHHHHHH
KDVAHALGVDTTGMTDAQGADAAIHAIQRLSADVGIPPGLGGLGMKETDVPILAANALKD
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEHHHHHH
ACGFTNPKQATQTEIETIFRAAA
HHCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]