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The map label for this gene is nadA [H]

Identifier: 192289657

GI number: 192289657

Start: 1323755

End: 1324867

Strand: Reverse

Name: nadA [H]

Synonym: Rpal_1247

Alternate gene names: 192289657

Gene position: 1324867-1323755 (Counterclockwise)

Preceding gene: 192289660

Following gene: 192289656

Centisome position: 23.07

GC content: 63.79

Gene sequence:

>1113_bases
ATGCCGCTTGCTGAACTCTACGGTCCGGAGAATTTCGGCCTGCCGCCGCATGCGCGCCAAGGATCGCTTCCGCGCGCGCC
GCTGAGTGCCACTGAACGCGCCCGCGCGCTCCCGATGCCGTCCTTGGAATGGACGCCGGAGGTCGAGGCCGCGACCGCGC
ACCTGTACGAGAAGGTGCAGACCGTCATTCCGCCGGTCGAGTGGCCGTTCATGGCGCCCTACGTCAAAGCGATCAACGAG
CTGAAGCGCGAGCGCGACGCCGTGATCCTGGCGCACAACTACCAGACGCCGGAAATCTTCCACTGCGTCGCCGACATCGT
CGGCGACTCGCTGCAACTCGCGATCGAAGCCACCAAGGTGAAAGCTTCGACCATCGTGCAGTGTGGCGTGCACTTCATGG
CCGAGACGTCGAAGATCCTGAATCCGGAGAAGCGCGTGCTGATCCCGGATTCCCGCGCTGGCTGCTCGCTCGCCTCTTCC
ATCACCGGTGCCGACGTTCGGCTGCTGCGCGAGAAATTCCCCGGCGTGCCGGTGGTCGCTTATGTCAACACCTCGGCCGA
CGTGAAGGCTGAGGTCGATATCTGCTGCACCTCGTCGAACGCCGTGCAGGTGGTCGAAAGCCTCGGCGTCGACCGCGTCA
TCATGGTGCCGGACCAGTATCTGGCGAAGTACGTCGCCTCCCAGACCAAGGTGAAGATCATCGCCTGGAAGGGCGCCTGC
GAGGTCCACGAGCGCTTCACCGGCGACGAGCTGCGCGTCTATCGCGAGGCAGATCCGAACGTGAAGATCATCGCGCATCC
GGAGTGTCCGCCGGATGTACTGGCCGAAGCCGACTTCACCGGCTCGACCGCGCACATGATCAACTGGGTCAAGACCCAGC
ATCCGAAGCGCGTGGTGATGATCACCGAGTGCTCGATGGCCGACAACGTCCAGGCCGAGCTGCGCGACGTCGAAATGGTG
CGGCCGTGCAATCTATGCCCGCACATGAAGCGGATCACGCTGGCGAAGATCCTCGACAGTCTGGTGTATCTGCGTGAGGA
AGTGACGGTCGATCCCGCCATCATCGCGCCGGCCCGGCGCTCGGTGGAGCGGATGATCAACCTGAACAACTGA

Upstream 100 bases:

>100_bases
GCAGCGGTTGGAAAGTTGCCGGCCCATCGTGGCCGGATTTCTCAAACCCAGCATATGCTCAAACTGAGTATATATTGGAG
CGCGGTACAAGGAGGCGTCG

Downstream 100 bases:

>100_bases
GCCTCAGGGCTCGCGACGAATGGCGGCGTCCGTGCCGCCATCGCTGTGCATCGAAGGCGTTCGCGGACAATCGCGTGAGA
GTTGGATCGCCGCATGAGCA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MPLAELYGPENFGLPPHARQGSLPRAPLSATERARALPMPSLEWTPEVEAATAHLYEKVQTVIPPVEWPFMAPYVKAINE
LKRERDAVILAHNYQTPEIFHCVADIVGDSLQLAIEATKVKASTIVQCGVHFMAETSKILNPEKRVLIPDSRAGCSLASS
ITGADVRLLREKFPGVPVVAYVNTSADVKAEVDICCTSSNAVQVVESLGVDRVIMVPDQYLAKYVASQTKVKIIAWKGAC
EVHERFTGDELRVYREADPNVKIIAHPECPPDVLAEADFTGSTAHMINWVKTQHPKRVVMITECSMADNVQAELRDVEMV
RPCNLCPHMKRITLAKILDSLVYLREEVTVDPAIIAPARRSVERMINLNN

Sequences:

>Translated_370_residues
MPLAELYGPENFGLPPHARQGSLPRAPLSATERARALPMPSLEWTPEVEAATAHLYEKVQTVIPPVEWPFMAPYVKAINE
LKRERDAVILAHNYQTPEIFHCVADIVGDSLQLAIEATKVKASTIVQCGVHFMAETSKILNPEKRVLIPDSRAGCSLASS
ITGADVRLLREKFPGVPVVAYVNTSADVKAEVDICCTSSNAVQVVESLGVDRVIMVPDQYLAKYVASQTKVKIIAWKGAC
EVHERFTGDELRVYREADPNVKIIAHPECPPDVLAEADFTGSTAHMINWVKTQHPKRVVMITECSMADNVQAELRDVEMV
RPCNLCPHMKRITLAKILDSLVYLREEVTVDPAIIAPARRSVERMINLNN
>Mature_369_residues
PLAELYGPENFGLPPHARQGSLPRAPLSATERARALPMPSLEWTPEVEAATAHLYEKVQTVIPPVEWPFMAPYVKAINEL
KRERDAVILAHNYQTPEIFHCVADIVGDSLQLAIEATKVKASTIVQCGVHFMAETSKILNPEKRVLIPDSRAGCSLASSI
TGADVRLLREKFPGVPVVAYVNTSADVKAEVDICCTSSNAVQVVESLGVDRVIMVPDQYLAKYVASQTKVKIIAWKGACE
VHERFTGDELRVYREADPNVKIIAHPECPPDVLAEADFTGSTAHMINWVKTQHPKRVVMITECSMADNVQAELRDVEMVR
PCNLCPHMKRITLAKILDSLVYLREEVTVDPAIIAPARRSVERMINLNN

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=316, Percent_Identity=35.7594936708861, Blast_Score=168, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 40975; Mature: 40844

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLAELYGPENFGLPPHARQGSLPRAPLSATERARALPMPSLEWTPEVEAATAHLYEKVQ
CCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
TVIPPVEWPFMAPYVKAINELKRERDAVILAHNYQTPEIFHCVADIVGDSLQLAIEATKV
HHCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEEEHHH
KASTIVQCGVHFMAETSKILNPEKRVLIPDSRAGCSLASSITGADVRLLREKFPGVPVVA
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHCCCHHHHHHHHHCCCCCEEE
YVNTSADVKAEVDICCTSSNAVQVVESLGVDRVIMVPDQYLAKYVASQTKVKIIAWKGAC
EECCCCCCEEEEEEEECCCHHHHHHHHCCCCEEEECCHHHHHHHHHCCCEEEEEEECCCH
EVHERFTGDELRVYREADPNVKIIAHPECPPDVLAEADFTGSTAHMINWVKTQHPKRVVM
HHHHHCCCCCEEEEECCCCCEEEEECCCCCHHHHCCCCCCCCHHHHHHHHHCCCCCEEEE
ITECSMADNVQAELRDVEMVRPCNLCPHMKRITLAKILDSLVYLREEVTVDPAIIAPARR
EEECCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHH
SVERMINLNN
HHHHHHCCCC
>Mature Secondary Structure 
PLAELYGPENFGLPPHARQGSLPRAPLSATERARALPMPSLEWTPEVEAATAHLYEKVQ
CCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
TVIPPVEWPFMAPYVKAINELKRERDAVILAHNYQTPEIFHCVADIVGDSLQLAIEATKV
HHCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEEEHHH
KASTIVQCGVHFMAETSKILNPEKRVLIPDSRAGCSLASSITGADVRLLREKFPGVPVVA
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHCCCHHHHHHHHHCCCCCEEE
YVNTSADVKAEVDICCTSSNAVQVVESLGVDRVIMVPDQYLAKYVASQTKVKIIAWKGAC
EECCCCCCEEEEEEEECCCHHHHHHHHCCCCEEEECCHHHHHHHHHCCCEEEEEEECCCH
EVHERFTGDELRVYREADPNVKIIAHPECPPDVLAEADFTGSTAHMINWVKTQHPKRVVM
HHHHHCCCCCEEEEECCCCCEEEEECCCCCHHHHCCCCCCCCHHHHHHHHHCCCCCEEEE
ITECSMADNVQAELRDVEMVRPCNLCPHMKRITLAKILDSLVYLREEVTVDPAIIAPARR
EEECCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHH
SVERMINLNN
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]