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The map label for this gene is mmgC [H]

Identifier: 192289597

GI number: 192289597

Start: 1259211

End: 1260356

Strand: Reverse

Name: mmgC [H]

Synonym: Rpal_1187

Alternate gene names: 192289597

Gene position: 1260356-1259211 (Counterclockwise)

Preceding gene: 192289598

Following gene: 192289594

Centisome position: 21.94

GC content: 63.79

Gene sequence:

>1146_bases
ATGGAATACCGATCGCCCTGGATGACCGAAGAGCTGGACACGTTCCGCGACCAGTTTCGCAAATTCCTCGCCAAGGATCT
CGCGCCCCACAGCGACAAGTGGCGGAAGCAGAAGATGGTCGATCGCTCGGCCTGGCTGAAGCTCGGCGAAATGGGCGCGC
TGCTGCCCAGCGTTCCGGAACAGTACGGCGGGCTCGGCGCCAGCTTCGCCTACGATGCCGCGGTCTATGAGGACATGGAG
AAGATCGTCCCGGACGCGCTGTCCGGCGTCACCGTGTCGAGCGGCATCGTGGCGCACTACATCCTCAACTACGGGTCGGA
GGAACAGAAGCGGCGTTGGCTACCCGGCATGGCGCGCGGCGAGCTGATCGGCGCGATCGCAATGACCGAACCCGGTACCG
GATCTGACCTGCAGAGCGTGCGCACCACCGCCAAGCTCGACGGCGACGACTACGTCATCAACGGCCAGAAGACCTTCATC
ACCAACGGCCAGAACTGCGACCTGATCATTGTCGTCGCCCGCACCGGCGGCGCCGGCGCCAAGGGGCTGTCGCTGATCGT
GCTGGAGACCAAGGACAACCCCGGTTTCAAGCGCGGCCGCAACCTCGACAAGATCGGCCTCCACGCCTCCGACACCTCCG
AGCTGTTCTTCGAGAACGCCCGCACGCCGAAGGAGAACCTGCTCGGCGGAGAGGAAGGCAAAGGCTTCGTGCAGCTGATG
CAGCAGCTGCCGCAAGAGCGGCTGATCATCGCGATCGGCGCGGTGGCGGCGATGGAGCGCGCGGTCGCGCTGACCTCGGA
ATACACGCGGGAGCGCAAGGCGTTCGGCCAACCGATCATCGAATTCCAGAACACCGCTTTCACGCTCGCCGAACGCAAGA
CCGAAGCCTTCATCGCGCGTGTGTTCGTCGATTACTGCCTGGTCCAGCTGGTCGCCGGCAATCTCGACGCCGTCACCGCC
TCGATGGCGAAATGGTGGACGACGCAAAAGCAGGTCGAGACCGTGGACGAGTGCCTGCAACTGCACGGCGGCTACGGCTA
CATGCAGGAATACCCGATCGGCCGGATGTTCATCGACTCGCGCATTCAGAAGATCTACGGCGGCACCAACGAGGTCATGA
AGCTGCTGATCGCCCGCTCGCTGTAA

Upstream 100 bases:

>100_bases
CAAGATACGGCGATCGCAACGGCTATCCTGCACCGCAGAACTGGCCTAGATCAGCGGGCGATGCGCCGTGCCAAGCGGCC
GCCCATTCGAGTGAGGAAAC

Downstream 100 bases:

>100_bases
CACGGCGCGCCGGCGCCACCGCTGCTGGTTCAAGCCAGCGACGCGGAGGCGCCGGTGGCGGCGTTCAGTCGCCGCTTTCC
GACACTTCGCGCTTGAGGCG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MEYRSPWMTEELDTFRDQFRKFLAKDLAPHSDKWRKQKMVDRSAWLKLGEMGALLPSVPEQYGGLGASFAYDAAVYEDME
KIVPDALSGVTVSSGIVAHYILNYGSEEQKRRWLPGMARGELIGAIAMTEPGTGSDLQSVRTTAKLDGDDYVINGQKTFI
TNGQNCDLIIVVARTGGAGAKGLSLIVLETKDNPGFKRGRNLDKIGLHASDTSELFFENARTPKENLLGGEEGKGFVQLM
QQLPQERLIIAIGAVAAMERAVALTSEYTRERKAFGQPIIEFQNTAFTLAERKTEAFIARVFVDYCLVQLVAGNLDAVTA
SMAKWWTTQKQVETVDECLQLHGGYGYMQEYPIGRMFIDSRIQKIYGGTNEVMKLLIARSL

Sequences:

>Translated_381_residues
MEYRSPWMTEELDTFRDQFRKFLAKDLAPHSDKWRKQKMVDRSAWLKLGEMGALLPSVPEQYGGLGASFAYDAAVYEDME
KIVPDALSGVTVSSGIVAHYILNYGSEEQKRRWLPGMARGELIGAIAMTEPGTGSDLQSVRTTAKLDGDDYVINGQKTFI
TNGQNCDLIIVVARTGGAGAKGLSLIVLETKDNPGFKRGRNLDKIGLHASDTSELFFENARTPKENLLGGEEGKGFVQLM
QQLPQERLIIAIGAVAAMERAVALTSEYTRERKAFGQPIIEFQNTAFTLAERKTEAFIARVFVDYCLVQLVAGNLDAVTA
SMAKWWTTQKQVETVDECLQLHGGYGYMQEYPIGRMFIDSRIQKIYGGTNEVMKLLIARSL
>Mature_381_residues
MEYRSPWMTEELDTFRDQFRKFLAKDLAPHSDKWRKQKMVDRSAWLKLGEMGALLPSVPEQYGGLGASFAYDAAVYEDME
KIVPDALSGVTVSSGIVAHYILNYGSEEQKRRWLPGMARGELIGAIAMTEPGTGSDLQSVRTTAKLDGDDYVINGQKTFI
TNGQNCDLIIVVARTGGAGAKGLSLIVLETKDNPGFKRGRNLDKIGLHASDTSELFFENARTPKENLLGGEEGKGFVQLM
QQLPQERLIIAIGAVAAMERAVALTSEYTRERKAFGQPIIEFQNTAFTLAERKTEAFIARVFVDYCLVQLVAGNLDAVTA
SMAKWWTTQKQVETVDECLQLHGGYGYMQEYPIGRMFIDSRIQKIYGGTNEVMKLLIARSL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=46.684350132626, Blast_Score=343, Evalue=2e-94,
Organism=Homo sapiens, GI7656849, Length=375, Percent_Identity=33.6, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI226958412, Length=379, Percent_Identity=32.7176781002639, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI226958414, Length=340, Percent_Identity=33.5294117647059, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI4557233, Length=380, Percent_Identity=32.3684210526316, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI4557231, Length=380, Percent_Identity=30.7894736842105, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI187960098, Length=380, Percent_Identity=30.7894736842105, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI21361497, Length=390, Percent_Identity=32.5641025641026, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI4501859, Length=375, Percent_Identity=29.6, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI76496475, Length=361, Percent_Identity=31.8559556786704, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI4557235, Length=361, Percent_Identity=31.8559556786704, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI4503943, Length=390, Percent_Identity=28.7179487179487, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI7669494, Length=368, Percent_Identity=29.0760869565217, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI48976061, Length=287, Percent_Identity=28.9198606271777, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI211971008, Length=287, Percent_Identity=28.9198606271777, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI38505218, Length=373, Percent_Identity=28.9544235924933, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI218563752, Length=289, Percent_Identity=25.2595155709343, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI87081958, Length=337, Percent_Identity=30.5637982195846, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1786223, Length=334, Percent_Identity=26.3473053892216, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI87082384, Length=274, Percent_Identity=27.007299270073, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538396, Length=381, Percent_Identity=33.8582677165354, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17533517, Length=365, Percent_Identity=33.4246575342466, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17508101, Length=374, Percent_Identity=31.8181818181818, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17570075, Length=378, Percent_Identity=30.4232804232804, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17551932, Length=370, Percent_Identity=32.1621621621622, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17534899, Length=376, Percent_Identity=30.8510638297872, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17506239, Length=377, Percent_Identity=31.2997347480106, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17505929, Length=364, Percent_Identity=31.8681318681319, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17569725, Length=378, Percent_Identity=29.3650793650794, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI71985184, Length=358, Percent_Identity=32.4022346368715, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71990804, Length=284, Percent_Identity=35.2112676056338, Blast_Score=151, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17534353, Length=382, Percent_Identity=28.7958115183246, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI32563615, Length=227, Percent_Identity=33.0396475770925, Blast_Score=127, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI71985192, Length=290, Percent_Identity=33.1034482758621, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71982178, Length=276, Percent_Identity=26.0869565217391, Blast_Score=110, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17562446, Length=335, Percent_Identity=27.1641791044776, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI86563383, Length=274, Percent_Identity=28.1021897810219, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI86563381, Length=274, Percent_Identity=28.1021897810219, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21355753, Length=384, Percent_Identity=33.8541666666667, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=30.4, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=30.4232804232804, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24666513, Length=376, Percent_Identity=29.2553191489362, Blast_Score=165, Evalue=4e-41,
Organism=Drosophila melanogaster, GI24646207, Length=378, Percent_Identity=30.1587301587302, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI281363737, Length=383, Percent_Identity=30.0261096605744, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI19920834, Length=379, Percent_Identity=30.3430079155673, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI45550141, Length=334, Percent_Identity=24.251497005988, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI221473076, Length=334, Percent_Identity=24.251497005988, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42334; Mature: 42334

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00073 ACYL_COA_DH_2 ; PS00287 CYSTATIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRSPWMTEELDTFRDQFRKFLAKDLAPHSDKWRKQKMVDRSAWLKLGEMGALLPSVPE
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
QYGGLGASFAYDAAVYEDMEKIVPDALSGVTVSSGIVAHYILNYGSEEQKRRWLPGMARG
HHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCC
ELIGAIAMTEPGTGSDLQSVRTTAKLDGDDYVINGQKTFITNGQNCDLIIVVARTGGAGA
CEEEEEEECCCCCCCHHHHHHHHHEECCCCEEECCCEEEEECCCCCCEEEEEEECCCCCC
KGLSLIVLETKDNPGFKRGRNLDKIGLHASDTSELFFENARTPKENLLGGEEGKGFVQLM
CCEEEEEEEECCCCCHHCCCCCCCCCCCCCCHHHHHHHCCCCCHHHCCCCCCCCHHHHHH
QQLPQERLIIAIGAVAAMERAVALTSEYTRERKAFGQPIIEFQNTAFTLAERKTEAFIAR
HHCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHH
VFVDYCLVQLVAGNLDAVTASMAKWWTTQKQVETVDECLQLHGGYGYMQEYPIGRMFIDS
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHH
RIQKIYGGTNEVMKLLIARSL
HHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MEYRSPWMTEELDTFRDQFRKFLAKDLAPHSDKWRKQKMVDRSAWLKLGEMGALLPSVPE
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
QYGGLGASFAYDAAVYEDMEKIVPDALSGVTVSSGIVAHYILNYGSEEQKRRWLPGMARG
HHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCC
ELIGAIAMTEPGTGSDLQSVRTTAKLDGDDYVINGQKTFITNGQNCDLIIVVARTGGAGA
CEEEEEEECCCCCCCHHHHHHHHHEECCCCEEECCCEEEEECCCCCCEEEEEEECCCCCC
KGLSLIVLETKDNPGFKRGRNLDKIGLHASDTSELFFENARTPKENLLGGEEGKGFVQLM
CCEEEEEEEECCCCCHHCCCCCCCCCCCCCCHHHHHHHCCCCCHHHCCCCCCCCHHHHHH
QQLPQERLIIAIGAVAAMERAVALTSEYTRERKAFGQPIIEFQNTAFTLAERKTEAFIAR
HHCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHH
VFVDYCLVQLVAGNLDAVTASMAKWWTTQKQVETVDECLQLHGGYGYMQEYPIGRMFIDS
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHH
RIQKIYGGTNEVMKLLIARSL
HHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]