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The map label for this gene is atpD2 [H]

Identifier: 192289482

GI number: 192289482

Start: 1124446

End: 1125870

Strand: Reverse

Name: atpD2 [H]

Synonym: Rpal_1057

Alternate gene names: 192289482

Gene position: 1125870-1124446 (Counterclockwise)

Preceding gene: 192289487

Following gene: 192289481

Centisome position: 19.6

GC content: 64.84

Gene sequence:

>1425_bases
ATGGATTCTGTCACGTCAATGGGAACGGTGGTATCAGTTCGAGGCGCCGTCGTCGACGTGGCTTTCGACGGCGAAACGCT
GCCGCCGATCAATACCGGCTTGATCGTCGAATGGGACCGGCCCGAGCCGCTCGTACTCGAAGTCCATAGCCATGTCGACC
CCCGGACCATTCGCAGCATTGCGCTGCAGGCCACCGCTGGTCTTGCGCGCAATACGGCGGTGCGCGCGACCGGCGTGCCG
ATTTCGGTACCGGTCGGAGATGCGGTTCTAGGACGCCTGCTCGACGTCGTCGGGACCGTCCAGGATCGCGGTCTTGCCCT
ACCATCCGATACGCCACGCCGCGGCATCCACAACCCGCCGCCGGCGCTCAATGAGGAGACCTCGACCAGCGCGGTGTTCG
AGACGGGCGTCAAGGTGATCGACCTGCTCGCACCGCTCGCCCAAGGCGGCAAAGCCGCGATGTTCGGCGGAGCCGGCGTC
GGCAAGACCGTGCTGGTGATGGAGCTGATCCACGCCATGGTTGAGAAATACCAGGGCATTTCGGTGTTTGCGGGTGTCGG
CGAGCGTTCCCGCGAGGGCCATGAGCTGCTGACGGATATGCAGCGTTCGGGAGTTCTCGCTCGCACGGTGCTCGTCTACG
GGCAGATGAACGAGCCGCCTGGCGCACGCTGGCGGGTACCGCTGACCGCATTGACGATCGCGGAGTATTTTCGCGACCAG
AAGCATCAGAATGTGTTGCTGCTGATGGACAACGTCTTCCGCTTCGTCCAGGCCGGAAGCGAGTTATCCAGCCTGTTGGG
ACGCCTGCCCTCGCGCGTCGGCTATCAGCCGACACTGGCCACCGAGGTGGCCTCGTTGCAGGAGCGGATCGCGTCGGTTG
CCGGTGCCGCCGTCACCGCGATCCAGGCCGTCTATGTTCCGGCCGATGACTTCACCGATCCGGCGGTGACAACAATCTCC
AGCCATACGGACAGCGTTATCATGCTGTCACGCTCGCTGGCGGCCCAAGGCTTTTATCCGGCCGTGGACCCGCTTGCCTC
GTCGTCGGTACTGCTCGATCCCCGGGTGGTCGGCGAAGAACACTATCGTCTGGCCGAACGTTGCCGCGAGACGCTCGCTC
GCTTCAAGGATCTGCAGGACATCATCGCACTGCTCGGCGTCGAGGAACTCGGCGCCGGCGACCGGCTGGTCGTCAAACGG
GCACGCCGCTTGCAGCGTTTCCTCAGCCAGCCTTTCACCGTGACGGAGGCCTTCACCGGCACGCCCGGCCGCAGCGTCCC
CCGCGCCGATACGCTGGCCGGCTGCCACGCCATTCTCGACGGTGAAGCCGACGCCTGGGCAGAGAGTTCGCTCTATATGA
TCGGGACCATCGATGAGGCCCGCGAGAAGGAGACGGCGGGCGCCAGAAAGGAAGCCGCGTCATGA

Upstream 100 bases:

>100_bases
CGCCTGAGCCTGAATGACGCCCGTTCGAAGTCAACCAACCGCGACTCTTGCCTGCCGGACGTTCGCAGCAGCTGATATTT
GAGAACACATCGGACATGCC

Downstream 100 bases:

>100_bases
GGCTCCGCATTGTCACGCCGCTCTCGGTCGTCGTCGAGGAAGACGGCGTCCTCGTCGTGCGCGCCGAAGACGCCACCGGC
AGCTTCGGGATATTGCCGGG

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta 2; F-ATPase subunit beta 2 [H]

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MDSVTSMGTVVSVRGAVVDVAFDGETLPPINTGLIVEWDRPEPLVLEVHSHVDPRTIRSIALQATAGLARNTAVRATGVP
ISVPVGDAVLGRLLDVVGTVQDRGLALPSDTPRRGIHNPPPALNEETSTSAVFETGVKVIDLLAPLAQGGKAAMFGGAGV
GKTVLVMELIHAMVEKYQGISVFAGVGERSREGHELLTDMQRSGVLARTVLVYGQMNEPPGARWRVPLTALTIAEYFRDQ
KHQNVLLLMDNVFRFVQAGSELSSLLGRLPSRVGYQPTLATEVASLQERIASVAGAAVTAIQAVYVPADDFTDPAVTTIS
SHTDSVIMLSRSLAAQGFYPAVDPLASSSVLLDPRVVGEEHYRLAERCRETLARFKDLQDIIALLGVEELGAGDRLVVKR
ARRLQRFLSQPFTVTEAFTGTPGRSVPRADTLAGCHAILDGEADAWAESSLYMIGTIDEAREKETAGARKEAAS

Sequences:

>Translated_474_residues
MDSVTSMGTVVSVRGAVVDVAFDGETLPPINTGLIVEWDRPEPLVLEVHSHVDPRTIRSIALQATAGLARNTAVRATGVP
ISVPVGDAVLGRLLDVVGTVQDRGLALPSDTPRRGIHNPPPALNEETSTSAVFETGVKVIDLLAPLAQGGKAAMFGGAGV
GKTVLVMELIHAMVEKYQGISVFAGVGERSREGHELLTDMQRSGVLARTVLVYGQMNEPPGARWRVPLTALTIAEYFRDQ
KHQNVLLLMDNVFRFVQAGSELSSLLGRLPSRVGYQPTLATEVASLQERIASVAGAAVTAIQAVYVPADDFTDPAVTTIS
SHTDSVIMLSRSLAAQGFYPAVDPLASSSVLLDPRVVGEEHYRLAERCRETLARFKDLQDIIALLGVEELGAGDRLVVKR
ARRLQRFLSQPFTVTEAFTGTPGRSVPRADTLAGCHAILDGEADAWAESSLYMIGTIDEAREKETAGARKEAAS
>Mature_474_residues
MDSVTSMGTVVSVRGAVVDVAFDGETLPPINTGLIVEWDRPEPLVLEVHSHVDPRTIRSIALQATAGLARNTAVRATGVP
ISVPVGDAVLGRLLDVVGTVQDRGLALPSDTPRRGIHNPPPALNEETSTSAVFETGVKVIDLLAPLAQGGKAAMFGGAGV
GKTVLVMELIHAMVEKYQGISVFAGVGERSREGHELLTDMQRSGVLARTVLVYGQMNEPPGARWRVPLTALTIAEYFRDQ
KHQNVLLLMDNVFRFVQAGSELSSLLGRLPSRVGYQPTLATEVASLQERIASVAGAAVTAIQAVYVPADDFTDPAVTTIS
SHTDSVIMLSRSLAAQGFYPAVDPLASSSVLLDPRVVGEEHYRLAERCRETLARFKDLQDIIALLGVEELGAGDRLVVKR
ARRLQRFLSQPFTVTEAFTGTPGRSVPRADTLAGCHAILDGEADAWAESSLYMIGTIDEAREKETAGARKEAAS

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=464, Percent_Identity=53.0172413793103, Blast_Score=474, Evalue=1e-134,
Organism=Homo sapiens, GI19913424, Length=302, Percent_Identity=30.794701986755, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI19913426, Length=378, Percent_Identity=24.8677248677249, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI19913428, Length=370, Percent_Identity=25.6756756756757, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI50345984, Length=282, Percent_Identity=26.241134751773, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI4757810, Length=282, Percent_Identity=26.241134751773, Blast_Score=96, Evalue=1e-19,
Organism=Escherichia coli, GI1790170, Length=456, Percent_Identity=50.6578947368421, Blast_Score=451, Evalue=1e-128,
Organism=Escherichia coli, GI1788251, Length=320, Percent_Identity=31.25, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1790172, Length=398, Percent_Identity=24.3718592964824, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI25144756, Length=463, Percent_Identity=52.0518358531317, Blast_Score=464, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI17565854, Length=321, Percent_Identity=31.4641744548287, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17570191, Length=366, Percent_Identity=24.5901639344262, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17510931, Length=367, Percent_Identity=25.6130790190736, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71988080, Length=282, Percent_Identity=26.5957446808511, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71988063, Length=282, Percent_Identity=26.5957446808511, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71988074, Length=295, Percent_Identity=23.728813559322, Blast_Score=73, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322581, Length=458, Percent_Identity=53.2751091703057, Blast_Score=480, Evalue=1e-136,
Organism=Saccharomyces cerevisiae, GI6319603, Length=370, Percent_Identity=26.2162162162162, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6319370, Length=297, Percent_Identity=26.2626262626263, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6320016, Length=264, Percent_Identity=28.030303030303, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24638766, Length=474, Percent_Identity=52.7426160337553, Blast_Score=480, Evalue=1e-136,
Organism=Drosophila melanogaster, GI28574560, Length=472, Percent_Identity=51.6949152542373, Blast_Score=456, Evalue=1e-128,
Organism=Drosophila melanogaster, GI24583992, Length=321, Percent_Identity=28.9719626168224, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24583988, Length=302, Percent_Identity=30.1324503311258, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24583986, Length=302, Percent_Identity=30.1324503311258, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24583984, Length=302, Percent_Identity=30.1324503311258, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI20129479, Length=300, Percent_Identity=30.3333333333333, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281361666, Length=370, Percent_Identity=25.9459459459459, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24646341, Length=370, Percent_Identity=25.9459459459459, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI17136796, Length=370, Percent_Identity=25.9459459459459, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24658560, Length=305, Percent_Identity=25.5737704918033, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24638768, Length=91, Percent_Identity=49.4505494505495, Blast_Score=79, Evalue=9e-15,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 50641; Mature: 50641

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSVTSMGTVVSVRGAVVDVAFDGETLPPINTGLIVEWDRPEPLVLEVHSHVDPRTIRSI
CCCCHHCCHHEEECCEEEEEEECCCCCCCCCCCEEEEECCCCCEEEEECCCCCHHHHHHH
ALQATAGLARNTAVRATGVPISVPVGDAVLGRLLDVVGTVQDRGLALPSDTPRRGIHNPP
HHHHHHCHHHCCEEEECCCEEECCCCHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCC
PALNEETSTSAVFETGVKVIDLLAPLAQGGKAAMFGGAGVGKTVLVMELIHAMVEKYQGI
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCC
SVFAGVGERSREGHELLTDMQRSGVLARTVLVYGQMNEPPGARWRVPLTALTIAEYFRDQ
EEEECCCCCCCCHHHHHHHHHHCCHHHHHHEEEECCCCCCCCEEECCHHHHHHHHHHHHH
KHQNVLLLMDNVFRFVQAGSELSSLLGRLPSRVGYQPTLATEVASLQERIASVAGAAVTA
CCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IQAVYVPADDFTDPAVTTISSHTDSVIMLSRSLAAQGFYPAVDPLASSSVLLDPRVVGEE
HHEEEECCCCCCCCHHEEECCCCCCEEEEHHHHHHCCCCCCCCCCCCCCEEECCHHCCHH
HYRLAERCRETLARFKDLQDIIALLGVEELGAGDRLVVKRARRLQRFLSQPFTVTEAFTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCC
TPGRSVPRADTLAGCHAILDGEADAWAESSLYMIGTIDEAREKETAGARKEAAS
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MDSVTSMGTVVSVRGAVVDVAFDGETLPPINTGLIVEWDRPEPLVLEVHSHVDPRTIRSI
CCCCHHCCHHEEECCEEEEEEECCCCCCCCCCCEEEEECCCCCEEEEECCCCCHHHHHHH
ALQATAGLARNTAVRATGVPISVPVGDAVLGRLLDVVGTVQDRGLALPSDTPRRGIHNPP
HHHHHHCHHHCCEEEECCCEEECCCCHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCC
PALNEETSTSAVFETGVKVIDLLAPLAQGGKAAMFGGAGVGKTVLVMELIHAMVEKYQGI
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCC
SVFAGVGERSREGHELLTDMQRSGVLARTVLVYGQMNEPPGARWRVPLTALTIAEYFRDQ
EEEECCCCCCCCHHHHHHHHHHCCHHHHHHEEEECCCCCCCCEEECCHHHHHHHHHHHHH
KHQNVLLLMDNVFRFVQAGSELSSLLGRLPSRVGYQPTLATEVASLQERIASVAGAAVTA
CCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IQAVYVPADDFTDPAVTTISSHTDSVIMLSRSLAAQGFYPAVDPLASSSVLLDPRVVGEE
HHEEEECCCCCCCCHHEEECCCCCCEEEEHHHHHHCCCCCCCCCCCCCCEEECCHHCCHH
HYRLAERCRETLARFKDLQDIIALLGVEELGAGDRLVVKRARRLQRFLSQPFTVTEAFTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCC
TPGRSVPRADTLAGCHAILDGEADAWAESSLYMIGTIDEAREKETAGARKEAAS
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA