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The map label for this gene is tldD [H]

Identifier: 192289321

GI number: 192289321

Start: 953466

End: 954893

Strand: Reverse

Name: tldD [H]

Synonym: Rpal_0893

Alternate gene names: 192289321

Gene position: 954893-953466 (Counterclockwise)

Preceding gene: 192289326

Following gene: 192289320

Centisome position: 16.62

GC content: 67.58

Gene sequence:

>1428_bases
ATGACCAACCCAGCCCAGACCTCGCTCATCGACCGCGCCAATCTCGATCGCGACGAGGTGAGGCGCGAGATCGCGCGGGG
GCTGCAGGGGGCGGACGATGGCGAGCTGTTTCTCGAATACAGCCAGACCGAGGCGCTCGCCTTCGACAATGGCCGGCTGA
AGCAGGCGACCTATGACACCGCGCAGGGCTTTGGTTTACGCGCCGTTAAGGACGACGCGGTCGGCTATGCGCATTCCTCG
GACGTGTCGCTGCCGGCGCTGATCCGGGCCGCCGACGCGGTCGCCGCGGTGCGCGGCGACTACAGCGGGAGCCTGTCGGT
GGCGCCGCCGCACACCAACGTGCAGCTGTACGGCGACGACAACCCGCTCGATGCGCCGGGCTTTGAAGCCAAGGTCAAGC
TGCTCGGCGAGATCGACGCCTATATCCGCGACAAGGATCCGCGGGTACGGCAGGTGTCGGTCTCGGTCGGCGCCACTTGG
CAGGTGGTTGAAATCCTGCGCCCCGACGGCGAGAGCTACCGCGACATCCGCCCGCTCGTGCGCGTCAACGTGTCGGTGGT
CGCCGGCCAGGGTGACCGCCAGGAGAGCGGCTCCAAGGGTTATGGCGGCCGCGAGCCTTATGCGCGGTTCATCGAGACCA
AGGCGTGGCGCGACGCCGCCGATGGCGCGCTGCGCGAAGCGCTGGTCAATCTCGAATCGGTGCCGGCGCCCGCCGGCGAG
ATGGACGTGGTGCTCGGCCCCGGCTGGCCCGGCGTGATGCTGCACGAGGCGGTCGGCCACGGCCTCGAGGGCGATTTCAA
CCGCAAGAAGACCTCCGCCTTCGCTGGCCTGCTCGGCCAACAGGTCGCCGCCAAGGGCGTCACCGTGGTGGACGACGGCA
CCATCTCGGCGCGGCGCGGCTCGCTGTCGATCGATGACGAAGGCACCCCGACCAGCCGCACCGTGCTGATCGAGGACGGC
ATCCTCACCGGCTACATGCAGGACCGCCAGAACGCCCGGCTGATGGGCATGAAGCCGACCGGCAACGGCCGCCGGCAGTC
CTATGCCCACGTCCCGATGCCGCGGATGACCAACACCTACATGCTGGCCGGTCAGCGCGACCCGGCCGAAATCCTCGCCT
CGGTAAAAAACGGCATCTACGCGGTGAACTTCGGCGGCGGCCAGGTCGATATCACGTCAGGCAAATACGTGTTCCAGTGC
ACCGAGGCCTACCGGATCGAGAACGGCAAGATCGGCGCGCCGCTGAAGGGGGCGATGCTGATCGGCAATGGTCCGACCGA
TTTGCACCGCATTTCCATGATCGGAAATGACATGCAGCTCGACGACGGCATCGGCACCTGCGGCAAGAACGGCCAGGGGG
TCCCGGTGGGTGTCGGCCAGCCGACGCTGCGCATGGACAAGATTACGGTCGGAGGCACCGGCGGATGA

Upstream 100 bases:

>100_bases
TCAGCGGGGCGAAGGCGCCGCGCCTAAATCCGCCAACCCCTCGCAGAACCAGCTCAGACCACCTATCTTGTCACCCAAAC
AACTTCGGGAACAGGACCTC

Downstream 100 bases:

>100_bases
CGACGAAGACGGAGACGGCCGCGAGCACCGCGCGGCGCTGGGGCTCGCAGCTGACGCAGCTCGCCGCCGTGGTGGCGATC
GTGCTGGTCGGCAAGGGCGC

Product: peptidase U62 modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MTNPAQTSLIDRANLDRDEVRREIARGLQGADDGELFLEYSQTEALAFDNGRLKQATYDTAQGFGLRAVKDDAVGYAHSS
DVSLPALIRAADAVAAVRGDYSGSLSVAPPHTNVQLYGDDNPLDAPGFEAKVKLLGEIDAYIRDKDPRVRQVSVSVGATW
QVVEILRPDGESYRDIRPLVRVNVSVVAGQGDRQESGSKGYGGREPYARFIETKAWRDAADGALREALVNLESVPAPAGE
MDVVLGPGWPGVMLHEAVGHGLEGDFNRKKTSAFAGLLGQQVAAKGVTVVDDGTISARRGSLSIDDEGTPTSRTVLIEDG
ILTGYMQDRQNARLMGMKPTGNGRRQSYAHVPMPRMTNTYMLAGQRDPAEILASVKNGIYAVNFGGGQVDITSGKYVFQC
TEAYRIENGKIGAPLKGAMLIGNGPTDLHRISMIGNDMQLDDGIGTCGKNGQGVPVGVGQPTLRMDKITVGGTGG

Sequences:

>Translated_475_residues
MTNPAQTSLIDRANLDRDEVRREIARGLQGADDGELFLEYSQTEALAFDNGRLKQATYDTAQGFGLRAVKDDAVGYAHSS
DVSLPALIRAADAVAAVRGDYSGSLSVAPPHTNVQLYGDDNPLDAPGFEAKVKLLGEIDAYIRDKDPRVRQVSVSVGATW
QVVEILRPDGESYRDIRPLVRVNVSVVAGQGDRQESGSKGYGGREPYARFIETKAWRDAADGALREALVNLESVPAPAGE
MDVVLGPGWPGVMLHEAVGHGLEGDFNRKKTSAFAGLLGQQVAAKGVTVVDDGTISARRGSLSIDDEGTPTSRTVLIEDG
ILTGYMQDRQNARLMGMKPTGNGRRQSYAHVPMPRMTNTYMLAGQRDPAEILASVKNGIYAVNFGGGQVDITSGKYVFQC
TEAYRIENGKIGAPLKGAMLIGNGPTDLHRISMIGNDMQLDDGIGTCGKNGQGVPVGVGQPTLRMDKITVGGTGG
>Mature_474_residues
TNPAQTSLIDRANLDRDEVRREIARGLQGADDGELFLEYSQTEALAFDNGRLKQATYDTAQGFGLRAVKDDAVGYAHSSD
VSLPALIRAADAVAAVRGDYSGSLSVAPPHTNVQLYGDDNPLDAPGFEAKVKLLGEIDAYIRDKDPRVRQVSVSVGATWQ
VVEILRPDGESYRDIRPLVRVNVSVVAGQGDRQESGSKGYGGREPYARFIETKAWRDAADGALREALVNLESVPAPAGEM
DVVLGPGWPGVMLHEAVGHGLEGDFNRKKTSAFAGLLGQQVAAKGVTVVDDGTISARRGSLSIDDEGTPTSRTVLIEDGI
LTGYMQDRQNARLMGMKPTGNGRRQSYAHVPMPRMTNTYMLAGQRDPAEILASVKNGIYAVNFGGGQVDITSGKYVFQCT
EAYRIENGKIGAPLKGAMLIGNGPTDLHRISMIGNDMQLDDGIGTCGKNGQGVPVGVGQPTLRMDKITVGGTGG

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=450, Percent_Identity=51.7777777777778, Blast_Score=442, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 50605; Mature: 50473

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPAQTSLIDRANLDRDEVRREIARGLQGADDGELFLEYSQTEALAFDNGRLKQATYDT
CCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEECCCCEEECCCCH
AQGFGLRAVKDDAVGYAHSSDVSLPALIRAADAVAAVRGDYSGSLSVAPPHTNVQLYGDD
HCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEECC
NPLDAPGFEAKVKLLGEIDAYIRDKDPRVRQVSVSVGATWQVVEILRPDGESYRDIRPLV
CCCCCCCCHHHEEEEEHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCCCCCHHHHCCEE
RVNVSVVAGQGDRQESGSKGYGGREPYARFIETKAWRDAADGALREALVNLESVPAPAGE
EEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
MDVVLGPGWPGVMLHEAVGHGLEGDFNRKKTSAFAGLLGQQVAAKGVTVVDDGTISARRG
EEEEECCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCEEECCC
SLSIDDEGTPTSRTVLIEDGILTGYMQDRQNARLMGMKPTGNGRRQSYAHVPMPRMTNTY
CEEECCCCCCCCEEEEEECCEEEEEHHCCCCCEEEEECCCCCCCCCCEECCCCCCCCCEE
MLAGQRDPAEILASVKNGIYAVNFGGGQVDITSGKYVFQCTEAYRIENGKIGAPLKGAML
EEECCCCHHHHHHHHHCCEEEEEECCCEEEEECCCEEEEEEEHEEECCCCCCCCCCCEEE
IGNGPTDLHRISMIGNDMQLDDGIGTCGKNGQGVPVGVGQPTLRMDKITVGGTGG
ECCCCCCCEEEEECCCCEEECCCCCCCCCCCCEEEECCCCCCEEEEEEEECCCCC
>Mature Secondary Structure 
TNPAQTSLIDRANLDRDEVRREIARGLQGADDGELFLEYSQTEALAFDNGRLKQATYDT
CCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEECCCCEEECCCCH
AQGFGLRAVKDDAVGYAHSSDVSLPALIRAADAVAAVRGDYSGSLSVAPPHTNVQLYGDD
HCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEECC
NPLDAPGFEAKVKLLGEIDAYIRDKDPRVRQVSVSVGATWQVVEILRPDGESYRDIRPLV
CCCCCCCCHHHEEEEEHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCCCCCHHHHCCEE
RVNVSVVAGQGDRQESGSKGYGGREPYARFIETKAWRDAADGALREALVNLESVPAPAGE
EEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
MDVVLGPGWPGVMLHEAVGHGLEGDFNRKKTSAFAGLLGQQVAAKGVTVVDDGTISARRG
EEEEECCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCEEECCC
SLSIDDEGTPTSRTVLIEDGILTGYMQDRQNARLMGMKPTGNGRRQSYAHVPMPRMTNTY
CEEECCCCCCCCEEEEEECCEEEEEHHCCCCCEEEEECCCCCCCCCCEECCCCCCCCCEE
MLAGQRDPAEILASVKNGIYAVNFGGGQVDITSGKYVFQCTEAYRIENGKIGAPLKGAML
EEECCCCHHHHHHHHHCCEEEEEECCCEEEEECCCEEEEEEEHEEECCCCCCCCCCCEEE
IGNGPTDLHRISMIGNDMQLDDGIGTCGKNGQGVPVGVGQPTLRMDKITVGGTGG
ECCCCCCCEEEEECCCCEEECCCCCCCCCCCCEEEECCCCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]