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The map label for this gene is lig [H]

Identifier: 192289299

GI number: 192289299

Start: 923945

End: 924991

Strand: Reverse

Name: lig [H]

Synonym: Rpal_0871

Alternate gene names: 192289299

Gene position: 924991-923945 (Counterclockwise)

Preceding gene: 192289301

Following gene: 192289298

Centisome position: 16.1

GC content: 68.48

Gene sequence:

>1047_bases
ATGCGACCGCACGACATCCTGATGCCGACCGCCGCCGGCCTGTGTTGCAGGCTCGGCGGCTTCCACATCGATCCGGTGCG
GCCGGTCGACCGCGCGGTGATTACTCACGGCCATTCCGATCACGCCCGCGCCGGGCACGGCACCGTGCTGGCGACCCAGC
CTACGCTCGACATGATGCGGCTACGCTACGGCGACAACTTCGCAGGCTCGACCCAGGCGGTCGCCTATGGCGAGACCATC
CGGCTCGGTGACACGACCGTCACGTTCCATCCTGCCGGCCATGTGCTCGGCTCAGCCCAGGTCGCGGTCGAAGCCGGCGG
CATCCGCATCGTCGCCTCCGGCGACTACAAGGACGCGCCCGACCCGACCTGCACGCCATTCGAGATCGTGTCGTGCGATG
TGTTCATCACCGAGGCGACCTTCGGGCTGCCGGTGTTTCGCCATCCCGATGCGGCAGGTGAAGTCAGAAAGCTGCTCGAC
TCCGTCGCCCTGTTTCCGGAACGCGCGCACCTGGTCGGCGCCTACTCGCTCGGCAAGGCGCAGCGGGTGATCGCGCTGAT
CCGGCAGGCCGGCTACGACGCACCAATCTATCTGCACGGCGCGATGGAGAAGATCACGCATTACTATCAGTCGTCCGGCA
TCGCGCTGGGCGAACTACGCCCGGTGAAGGGCGTCAAGAAGGCCGAGCTGGCCGGCACCATTACGGTGGCGCCGCCGTCA
GCGACCTCCGATCTCTGGACACGCCGCTTCCCCGATCCGCTCACCGCGTTCGCCTCGGGGTGGATGCGGGTGCGCGCCCG
TGCCCGCCAGCGCGGCGTCGAACTGCCGTTGGTGATCTCCGACCACGCCGATTGGGACGGCCTCACCGCCACCATCGCCG
CCACCGGCGCCGGCGAAGTCTGGGTCACCCACGGCCAGGAGGACGCGCTGGTGCATTGGTGCCAGACCAAGGGCCTCGCT
GCGCGGCCGCTCGACCTGGTCGGCTATGGCGACGAAGATGAAGACGTCGGCATGCCGACCGGCGAGAGCGAGGCCGCAGA
GGCATGA

Upstream 100 bases:

>100_bases
GGCAAGAACATTTCCGGACGACAGGAACAGGTACGTCGGCATCGACGGAACCCGGCGGGTTAAGACTCGTTTGAAAGGCA
GGCCCGCCTATATAGCGAAG

Downstream 100 bases:

>100_bases
ATCGCTTCGCCGAACTGCTCGACCGCCTCGGCTATGAGCCCGGCCGTAACAACAAGCTGCGGCTGATCACCAATTACTTT
CGCGAGGTCGAAGATCCCGA

Product: metallo-hydrolase/oxidoreductase

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MRPHDILMPTAAGLCCRLGGFHIDPVRPVDRAVITHGHSDHARAGHGTVLATQPTLDMMRLRYGDNFAGSTQAVAYGETI
RLGDTTVTFHPAGHVLGSAQVAVEAGGIRIVASGDYKDAPDPTCTPFEIVSCDVFITEATFGLPVFRHPDAAGEVRKLLD
SVALFPERAHLVGAYSLGKAQRVIALIRQAGYDAPIYLHGAMEKITHYYQSSGIALGELRPVKGVKKAELAGTITVAPPS
ATSDLWTRRFPDPLTAFASGWMRVRARARQRGVELPLVISDHADWDGLTATIAATGAGEVWVTHGQEDALVHWCQTKGLA
ARPLDLVGYGDEDEDVGMPTGESEAAEA

Sequences:

>Translated_348_residues
MRPHDILMPTAAGLCCRLGGFHIDPVRPVDRAVITHGHSDHARAGHGTVLATQPTLDMMRLRYGDNFAGSTQAVAYGETI
RLGDTTVTFHPAGHVLGSAQVAVEAGGIRIVASGDYKDAPDPTCTPFEIVSCDVFITEATFGLPVFRHPDAAGEVRKLLD
SVALFPERAHLVGAYSLGKAQRVIALIRQAGYDAPIYLHGAMEKITHYYQSSGIALGELRPVKGVKKAELAGTITVAPPS
ATSDLWTRRFPDPLTAFASGWMRVRARARQRGVELPLVISDHADWDGLTATIAATGAGEVWVTHGQEDALVHWCQTKGLA
ARPLDLVGYGDEDEDVGMPTGESEAAEA
>Mature_348_residues
MRPHDILMPTAAGLCCRLGGFHIDPVRPVDRAVITHGHSDHARAGHGTVLATQPTLDMMRLRYGDNFAGSTQAVAYGETI
RLGDTTVTFHPAGHVLGSAQVAVEAGGIRIVASGDYKDAPDPTCTPFEIVSCDVFITEATFGLPVFRHPDAAGEVRKLLD
SVALFPERAHLVGAYSLGKAQRVIALIRQAGYDAPIYLHGAMEKITHYYQSSGIALGELRPVKGVKKAELAGTITVAPPS
ATSDLWTRRFPDPLTAFASGWMRVRARARQRGVELPLVISDHADWDGLTATIAATGAGEVWVTHGQEDALVHWCQTKGLA
ARPLDLVGYGDEDEDVGMPTGESEAAEA

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATP- dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011108 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N; PF07521 RMMBL [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 37189; Mature: 37189

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPHDILMPTAAGLCCRLGGFHIDPVRPVDRAVITHGHSDHARAGHGTVLATQPTLDMMR
CCCCCEECCCHHHHHHHCCCEECCCCCCHHHHHEECCCCCCCCCCCCEEEEECCCHHHHH
LRYGDNFAGSTQAVAYGETIRLGDTTVTFHPAGHVLGSAQVAVEAGGIRIVASGDYKDAP
HHCCCCCCCCCEEEEECCEEEECCEEEEECCCCCCCCCEEEEEEECCEEEEECCCCCCCC
DPTCTPFEIVSCDVFITEATFGLPVFRHPDAAGEVRKLLDSVALFPERAHLVGAYSLGKA
CCCCCCEEEEEEEEEEEEHCCCCCEEECCCCHHHHHHHHHHHHCCCCHHHEEEEHHHCHH
QRVIALIRQAGYDAPIYLHGAMEKITHYYQSSGIALGELRPVKGVKKAELAGTITVAPPS
HHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHCEEEEECCCC
ATSDLWTRRFPDPLTAFASGWMRVRARARQRGVELPLVISDHADWDGLTATIAATGAGEV
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCCCCE
WVTHGQEDALVHWCQTKGLAARPLDLVGYGDEDEDVGMPTGESEAAEA
EEEECCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRPHDILMPTAAGLCCRLGGFHIDPVRPVDRAVITHGHSDHARAGHGTVLATQPTLDMMR
CCCCCEECCCHHHHHHHCCCEECCCCCCHHHHHEECCCCCCCCCCCCEEEEECCCHHHHH
LRYGDNFAGSTQAVAYGETIRLGDTTVTFHPAGHVLGSAQVAVEAGGIRIVASGDYKDAP
HHCCCCCCCCCEEEEECCEEEECCEEEEECCCCCCCCCEEEEEEECCEEEEECCCCCCCC
DPTCTPFEIVSCDVFITEATFGLPVFRHPDAAGEVRKLLDSVALFPERAHLVGAYSLGKA
CCCCCCEEEEEEEEEEEEHCCCCCEEECCCCHHHHHHHHHHHHCCCCHHHEEEEHHHCHH
QRVIALIRQAGYDAPIYLHGAMEKITHYYQSSGIALGELRPVKGVKKAELAGTITVAPPS
HHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCCEEEECCCCCCCCCHHHHCEEEEECCCC
ATSDLWTRRFPDPLTAFASGWMRVRARARQRGVELPLVISDHADWDGLTATIAATGAGEV
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCCCCE
WVTHGQEDALVHWCQTKGLAARPLDLVGYGDEDEDVGMPTGESEAAEA
EEEECCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA