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The map label for this gene is yngJ [H]

Identifier: 192289276

GI number: 192289276

Start: 898261

End: 899526

Strand: Reverse

Name: yngJ [H]

Synonym: Rpal_0848

Alternate gene names: 192289276

Gene position: 899526-898261 (Counterclockwise)

Preceding gene: 192289277

Following gene: 192289274

Centisome position: 15.66

GC content: 64.22

Gene sequence:

>1266_bases
ATGGATTTCGACCACAGCGACAAGGTGCAACGGCTGCGCGCGCAGCTGTCCGACTTCATGCGTTTCCACGTCGCGCCGGC
CAATGTCGCCTGGCATCGCGAGGTGGCCGCGGGGCACTATCCGCTGGCTCTGATCGAGCGGCTGAAGTCGCGGGCGTTTT
CCGAAGATCTCTGGAATCTGTTTCTGCCGGGCCTGCGGGATGAGGATCCAGGCCAGCGTCTTAGCAACGTCGAATATGCG
CCGCTCGCCGAGATCATGGGCCGGGTGCATTGGGCGTCAGAAGTATTCAACTGCAACGCGCCCGACACCGGCAACATGGA
GTTGCTGCATCTGGCAGCGACGCCAGAGCAGCGCGCCGAGTGGCTCGATCCGCTGCTGATCGGCGAAATCCGCTCCTGCT
TCGCGATGAGCGAGCCGGATGCCGCCTCGTCGGACGCGCGCAATATCCGCACCACCATCACCCGTGACGGCGACGACTAC
GTCATCAACGGCCGCAAATGGTTCATCACCGGGGCGGCGCATCCGAACTGCAAATTGGCGATCGTGATGGGCGTCACCGG
CGAACACCTGCCGGCAACTTCGACCGAGCGGCACTCGATGCTGCTGGTGCCGATGAACACGCCGGGGCTTTCGATCGTCC
GCAACATCCCGGTGATGCACTATCACTCGCCGGAAGGGCATTGTGAGCTGGTGTTCCGCAACGTCCGGGTACCGGCCGCC
AATCTGCTCGGCGAGGAAGGTAAAGGCTTTCGACTGGCGCAGGATCGGCTCGGTCCCGGCCGGGTACATCATTGCATGCG
GACCATCGGCCAATGCGAGGTCGCGCTCGAACTGATGGCGGAGCGTGCGCTCGAACGCGTGGCGTTCGGCAAGCACCTTG
CCGACTTCGCGAATATTCAAGACTGGATCGCCGAATCGCGGCTGGAGATCGATCAGGCGCGGCTGCTGGTGATGCAGGCG
GCGCACCGCATGGATCGCGCCGGCAACGCCGCGGCGCGGGTCGATGTCTCGGCGATCAAGCTAGTGGCGGCGCGGCTGCA
AACGAGGATCGTCGATCGCGCCATGCAGGTGTTCGGGGCGATGGGCCTGACGCCGGATACGCCATTGTCTTACTTATGGA
CCTGGGGCCGCGCGATGCGGTTTCTCGACGGGCCTGATGAGGTGCATCTGCGCGTGGTGGCCCGAGCCGAACTGGCGAAG
GCGAAAGCCCAGGCGGGCCAAAACGCCCACCACTTCGTTCCACCGTCGCAATTGCTGTCGGAGTGA

Upstream 100 bases:

>100_bases
TCAGCCTGAAGCGCAATTGATGCGGTCGCAGCGACGCCGCGTGCCGGCGCCACCGACCTCGGCGGACCGCTCCGCCGCCC
TTCCCGCCTGAGAGCCGCGT

Downstream 100 bases:

>100_bases
TCAGCGCCGGGCCGGCTGGGCCATCACGGTGACGATCCAGCGCGGGGTCTCGCCGGTCTTGTCTTCCTTGACGGCGCGAA
CGATGCCGGTGACCGAGGAG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MDFDHSDKVQRLRAQLSDFMRFHVAPANVAWHREVAAGHYPLALIERLKSRAFSEDLWNLFLPGLRDEDPGQRLSNVEYA
PLAEIMGRVHWASEVFNCNAPDTGNMELLHLAATPEQRAEWLDPLLIGEIRSCFAMSEPDAASSDARNIRTTITRDGDDY
VINGRKWFITGAAHPNCKLAIVMGVTGEHLPATSTERHSMLLVPMNTPGLSIVRNIPVMHYHSPEGHCELVFRNVRVPAA
NLLGEEGKGFRLAQDRLGPGRVHHCMRTIGQCEVALELMAERALERVAFGKHLADFANIQDWIAESRLEIDQARLLVMQA
AHRMDRAGNAAARVDVSAIKLVAARLQTRIVDRAMQVFGAMGLTPDTPLSYLWTWGRAMRFLDGPDEVHLRVVARAELAK
AKAQAGQNAHHFVPPSQLLSE

Sequences:

>Translated_421_residues
MDFDHSDKVQRLRAQLSDFMRFHVAPANVAWHREVAAGHYPLALIERLKSRAFSEDLWNLFLPGLRDEDPGQRLSNVEYA
PLAEIMGRVHWASEVFNCNAPDTGNMELLHLAATPEQRAEWLDPLLIGEIRSCFAMSEPDAASSDARNIRTTITRDGDDY
VINGRKWFITGAAHPNCKLAIVMGVTGEHLPATSTERHSMLLVPMNTPGLSIVRNIPVMHYHSPEGHCELVFRNVRVPAA
NLLGEEGKGFRLAQDRLGPGRVHHCMRTIGQCEVALELMAERALERVAFGKHLADFANIQDWIAESRLEIDQARLLVMQA
AHRMDRAGNAAARVDVSAIKLVAARLQTRIVDRAMQVFGAMGLTPDTPLSYLWTWGRAMRFLDGPDEVHLRVVARAELAK
AKAQAGQNAHHFVPPSQLLSE
>Mature_421_residues
MDFDHSDKVQRLRAQLSDFMRFHVAPANVAWHREVAAGHYPLALIERLKSRAFSEDLWNLFLPGLRDEDPGQRLSNVEYA
PLAEIMGRVHWASEVFNCNAPDTGNMELLHLAATPEQRAEWLDPLLIGEIRSCFAMSEPDAASSDARNIRTTITRDGDDY
VINGRKWFITGAAHPNCKLAIVMGVTGEHLPATSTERHSMLLVPMNTPGLSIVRNIPVMHYHSPEGHCELVFRNVRVPAA
NLLGEEGKGFRLAQDRLGPGRVHHCMRTIGQCEVALELMAERALERVAFGKHLADFANIQDWIAESRLEIDQARLLVMQA
AHRMDRAGNAAARVDVSAIKLVAARLQTRIVDRAMQVFGAMGLTPDTPLSYLWTWGRAMRFLDGPDEVHLRVVARAELAK
AKAQAGQNAHHFVPPSQLLSE

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI211971008, Length=398, Percent_Identity=51.7587939698493, Blast_Score=380, Evalue=1e-105,
Organism=Homo sapiens, GI48976061, Length=398, Percent_Identity=51.7587939698493, Blast_Score=380, Evalue=1e-105,
Organism=Homo sapiens, GI38505218, Length=405, Percent_Identity=47.9012345679012, Blast_Score=379, Evalue=1e-105,
Organism=Homo sapiens, GI4557233, Length=282, Percent_Identity=31.9148936170213, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI4501859, Length=344, Percent_Identity=28.7790697674419, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI21361497, Length=353, Percent_Identity=26.3456090651558, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI4557231, Length=409, Percent_Identity=23.4718826405868, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI187960098, Length=409, Percent_Identity=23.4718826405868, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI226958412, Length=396, Percent_Identity=25.5050505050505, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI7656849, Length=283, Percent_Identity=28.9752650176678, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI4501857, Length=316, Percent_Identity=26.8987341772152, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI226958414, Length=281, Percent_Identity=27.4021352313167, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI4557235, Length=351, Percent_Identity=24.2165242165242, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI76496475, Length=351, Percent_Identity=24.2165242165242, Blast_Score=92, Evalue=7e-19,
Organism=Escherichia coli, GI87081958, Length=308, Percent_Identity=28.8961038961039, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI1786223, Length=268, Percent_Identity=26.4925373134328, Blast_Score=99, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17562446, Length=362, Percent_Identity=50.5524861878453, Blast_Score=371, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17508101, Length=283, Percent_Identity=30.0353356890459, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17534899, Length=400, Percent_Identity=24.75, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17533517, Length=288, Percent_Identity=31.25, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17569725, Length=401, Percent_Identity=23.6907730673317, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17570075, Length=414, Percent_Identity=23.4299516908213, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17506239, Length=283, Percent_Identity=28.9752650176678, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71985184, Length=326, Percent_Identity=26.3803680981595, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17538396, Length=284, Percent_Identity=27.112676056338, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71990804, Length=216, Percent_Identity=32.8703703703704, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17505929, Length=318, Percent_Identity=25.7861635220126, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17551932, Length=280, Percent_Identity=26.4285714285714, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71985192, Length=265, Percent_Identity=26.4150943396226, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI32563615, Length=187, Percent_Identity=29.4117647058824, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI21356377, Length=278, Percent_Identity=32.0143884892086, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24646207, Length=394, Percent_Identity=29.1878172588832, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24666513, Length=280, Percent_Identity=29.2857142857143, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI281363737, Length=371, Percent_Identity=25.8760107816712, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24660351, Length=295, Percent_Identity=25.7627118644068, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21355753, Length=285, Percent_Identity=25.9649122807018, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 46991; Mature: 46991

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS00018 EF_HAND_1 ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFDHSDKVQRLRAQLSDFMRFHVAPANVAWHREVAAGHYPLALIERLKSRAFSEDLWNL
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
FLPGLRDEDPGQRLSNVEYAPLAEIMGRVHWASEVFNCNAPDTGNMELLHLAATPEQRAE
HCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHH
WLDPLLIGEIRSCFAMSEPDAASSDARNIRTTITRDGDDYVINGRKWFITGAAHPNCKLA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEECCEEEEEECCCCCCCEEE
IVMGVTGEHLPATSTERHSMLLVPMNTPGLSIVRNIPVMHYHSPEGHCELVFRNVRVPAA
EEECCCCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCEEEEECCCCCEEEEEECCCCCHH
NLLGEEGKGFRLAQDRLGPGRVHHCMRTIGQCEVALELMAERALERVAFGKHLADFANIQ
HHCCCCCCCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DWIAESRLEIDQARLLVMQAAHRMDRAGNAAARVDVSAIKLVAARLQTRIVDRAMQVFGA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHC
MGLTPDTPLSYLWTWGRAMRFLDGPDEVHLRVVARAELAKAKAQAGQNAHHFVPPSQLLS
CCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCCCHHHHHC
E
C
>Mature Secondary Structure
MDFDHSDKVQRLRAQLSDFMRFHVAPANVAWHREVAAGHYPLALIERLKSRAFSEDLWNL
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
FLPGLRDEDPGQRLSNVEYAPLAEIMGRVHWASEVFNCNAPDTGNMELLHLAATPEQRAE
HCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHH
WLDPLLIGEIRSCFAMSEPDAASSDARNIRTTITRDGDDYVINGRKWFITGAAHPNCKLA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEECCEEEEEECCCCCCCEEE
IVMGVTGEHLPATSTERHSMLLVPMNTPGLSIVRNIPVMHYHSPEGHCELVFRNVRVPAA
EEECCCCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCEEEEECCCCCEEEEEECCCCCHH
NLLGEEGKGFRLAQDRLGPGRVHHCMRTIGQCEVALELMAERALERVAFGKHLADFANIQ
HHCCCCCCCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DWIAESRLEIDQARLLVMQAAHRMDRAGNAAARVDVSAIKLVAARLQTRIVDRAMQVFGA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHC
MGLTPDTPLSYLWTWGRAMRFLDGPDEVHLRVVARAELAKAKAQAGQNAHHFVPPSQLLS
CCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCCCHHHHHC
E
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]