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The map label for this gene is tlyC [H]

Identifier: 192288880

GI number: 192288880

Start: 484575

End: 485720

Strand: Reverse

Name: tlyC [H]

Synonym: Rpal_0449

Alternate gene names: 192288880

Gene position: 485720-484575 (Counterclockwise)

Preceding gene: 192288881

Following gene: 192288879

Centisome position: 8.46

GC content: 66.93

Gene sequence:

>1146_bases
ATGCCCGACGGCGACAGAGCCGAGAACGGTTCGCAGGCCTCGCTGCAGGACTCCACGCGCGGCCAGTTACCCGCGGTGGT
GCATCAGGGCGAAGTGCTGCATCCGCATGGCGGCAGTTGGCTGATCCGTGCGATCCGTTCGCTGTTCGGCTGGAAGCCCG
GCTCGGTGCGCGACGACCTGCAGGTCGTGCTCGACACCAGCCCGCCCGACGACACCGGCTTCTCGACGCTCGAGCGCACG
ATGCTGCGCAACATCCTCGGGCTGCACGATCGCCGGATCGCCGACGTGATGGTGCATCGCGCCGACATCGTCGCGATCAA
GCAGGACATCCAGCTCGGCGAATTGCTCAGCCTGTTTCAGGACGCAGCGCATTCGCGGCTCGTGGTTTACAACGAAACGC
TCGACGATCCGGTCGGCATCGTTCACATCCGCGACCTCGTGGCGTTCATGACCGCAAAGGCGAAGGTGCCGCCGGCGACG
GTCGCCAAGCGCAAGAAGGCGCTGCCCGCGGGCCTCGATCTGCGCGCGATCGATCTGAAGATGCCGCTGACCGAAACCGG
CATCATCCGCAAGCTGCTGTATGTGCCGCCGTCGATGCGGGCGATCGACCTGCTGGCGCAGATGCAGGCGGCGCGCATCC
ATCTGGCGCTGGTGGTCGACGAATACGGCGGTACTGATGGCCTGGTCTCGATCGAAGATATCGTCGAACAGATCGTCGGC
GAGATCGATGATGAACACGACTCGACCGAGCCGCCGTCGATCGTGCGCCAGGCCGACGGCTCGTTCATCGCCGATGCGCG
AGCCAGTCTGGAAGACGTCCGCGCCATGATCGGCGATCAGTTCGTCACCGGCGAAGCGGGCGAAGACGTCGAAACCCTCG
GCGGTTACCTCGTCAACCACGTCGGCCGGCTGCCGGTTCGCGGCGAAGTGATCGCCGGCCCCGGCACCTTCGAATTCGAA
GTGCTCGACGCCGACCCACGGCGGGTGAAGCGGTTGCGGATCGGACCGCGCAAGGAACGCCCCGCCCCGCGCACACGCGA
CAGCCGGCGGCGCGAGACCGCGACCGATTCCGCCGCGCCGCAGACTACTGACAGCGGCGGATCCACCTCCTCTCCACCTG
CCGGCGACGGGACCGGTTCGCCGTGA

Upstream 100 bases:

>100_bases
ACCGATGAGGAAGCCGAGGAGATGGAAGACGCCGAACGCGCAATCCTGGCGCGGCTCGGGATTCCGGATCCGTATGCAGG
CCAGGATCGGGTGAGCTGAC

Downstream 100 bases:

>100_bases
CGCGTCGGGGTGTGCTGAGCCGGATCGCCTCGGGCATCATCCTGGCGTGGGGCTGGAAACGCGCCGTGATCGCGCTGCTG
GCCGGCGCACTCTCCTCGCT

Product: CBS domain containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MPDGDRAENGSQASLQDSTRGQLPAVVHQGEVLHPHGGSWLIRAIRSLFGWKPGSVRDDLQVVLDTSPPDDTGFSTLERT
MLRNILGLHDRRIADVMVHRADIVAIKQDIQLGELLSLFQDAAHSRLVVYNETLDDPVGIVHIRDLVAFMTAKAKVPPAT
VAKRKKALPAGLDLRAIDLKMPLTETGIIRKLLYVPPSMRAIDLLAQMQAARIHLALVVDEYGGTDGLVSIEDIVEQIVG
EIDDEHDSTEPPSIVRQADGSFIADARASLEDVRAMIGDQFVTGEAGEDVETLGGYLVNHVGRLPVRGEVIAGPGTFEFE
VLDADPRRVKRLRIGPRKERPAPRTRDSRRRETATDSAAPQTTDSGGSTSSPPAGDGTGSP

Sequences:

>Translated_381_residues
MPDGDRAENGSQASLQDSTRGQLPAVVHQGEVLHPHGGSWLIRAIRSLFGWKPGSVRDDLQVVLDTSPPDDTGFSTLERT
MLRNILGLHDRRIADVMVHRADIVAIKQDIQLGELLSLFQDAAHSRLVVYNETLDDPVGIVHIRDLVAFMTAKAKVPPAT
VAKRKKALPAGLDLRAIDLKMPLTETGIIRKLLYVPPSMRAIDLLAQMQAARIHLALVVDEYGGTDGLVSIEDIVEQIVG
EIDDEHDSTEPPSIVRQADGSFIADARASLEDVRAMIGDQFVTGEAGEDVETLGGYLVNHVGRLPVRGEVIAGPGTFEFE
VLDADPRRVKRLRIGPRKERPAPRTRDSRRRETATDSAAPQTTDSGGSTSSPPAGDGTGSP
>Mature_380_residues
PDGDRAENGSQASLQDSTRGQLPAVVHQGEVLHPHGGSWLIRAIRSLFGWKPGSVRDDLQVVLDTSPPDDTGFSTLERTM
LRNILGLHDRRIADVMVHRADIVAIKQDIQLGELLSLFQDAAHSRLVVYNETLDDPVGIVHIRDLVAFMTAKAKVPPATV
AKRKKALPAGLDLRAIDLKMPLTETGIIRKLLYVPPSMRAIDLLAQMQAARIHLALVVDEYGGTDGLVSIEDIVEQIVGE
IDDEHDSTEPPSIVRQADGSFIADARASLEDVRAMIGDQFVTGEAGEDVETLGGYLVNHVGRLPVRGEVIAGPGTFEFEV
LDADPRRVKRLRIGPRKERPAPRTRDSRRRETATDSAAPQTTDSGGSTSSPPAGDGTGSP

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=281, Percent_Identity=27.0462633451957, Blast_Score=102, Evalue=8e-22,
Organism=Escherichia coli, GI1786879, Length=300, Percent_Identity=30.6666666666667, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87082033, Length=276, Percent_Identity=28.6231884057971, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI145693175, Length=258, Percent_Identity=26.3565891472868, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1790664, Length=282, Percent_Identity=22.3404255319149, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788119, Length=281, Percent_Identity=26.6903914590747, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 41242; Mature: 41111

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDGDRAENGSQASLQDSTRGQLPAVVHQGEVLHPHGGSWLIRAIRSLFGWKPGSVRDDL
CCCCCCCCCCCCCCCCCCCCCCCCCEECCCCEECCCCCHHHHHHHHHHHCCCCCCCCCCE
QVVLDTSPPDDTGFSTLERTMLRNILGLHDRRIADVMVHRADIVAIKQDIQLGELLSLFQ
EEEECCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
DAAHSRLVVYNETLDDPVGIVHIRDLVAFMTAKAKVPPATVAKRKKALPAGLDLRAIDLK
HHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEEE
MPLTETGIIRKLLYVPPSMRAIDLLAQMQAARIHLALVVDEYGGTDGLVSIEDIVEQIVG
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEEEEEECCCCCCCEEEHHHHHHHHHH
EIDDEHDSTEPPSIVRQADGSFIADARASLEDVRAMIGDQFVTGEAGEDVETLGGYLVNH
HCCCCCCCCCCCHHHHHCCCCEEHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHH
VGRLPVRGEVIAGPGTFEFEVLDADPRRVKRLRIGPRKERPAPRTRDSRRRETATDSAAP
HCCCCCCCEEEECCCCEEEEEECCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCC
QTTDSGGSTSSPPAGDGTGSP
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PDGDRAENGSQASLQDSTRGQLPAVVHQGEVLHPHGGSWLIRAIRSLFGWKPGSVRDDL
CCCCCCCCCCCCCCCCCCCCCCCCEECCCCEECCCCCHHHHHHHHHHHCCCCCCCCCCE
QVVLDTSPPDDTGFSTLERTMLRNILGLHDRRIADVMVHRADIVAIKQDIQLGELLSLFQ
EEEECCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
DAAHSRLVVYNETLDDPVGIVHIRDLVAFMTAKAKVPPATVAKRKKALPAGLDLRAIDLK
HHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEEE
MPLTETGIIRKLLYVPPSMRAIDLLAQMQAARIHLALVVDEYGGTDGLVSIEDIVEQIVG
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEEEEEECCCCCCCEEEHHHHHHHHHH
EIDDEHDSTEPPSIVRQADGSFIADARASLEDVRAMIGDQFVTGEAGEDVETLGGYLVNH
HCCCCCCCCCCCHHHHHCCCCEEHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHH
VGRLPVRGEVIAGPGTFEFEVLDADPRRVKRLRIGPRKERPAPRTRDSRRRETATDSAAP
HCCCCCCCEEEECCCCEEEEEECCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCC
QTTDSGGSTSSPPAGDGTGSP
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA