| Definition | Rhodopseudomonas palustris TIE-1 chromosome, complete genome. |
|---|---|
| Accession | NC_011004 |
| Length | 5,744,041 |
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The map label for this gene is sdh [H]
Identifier: 192288854
GI number: 192288854
Start: 453845
End: 454624
Strand: Reverse
Name: sdh [H]
Synonym: Rpal_0423
Alternate gene names: 192288854
Gene position: 454624-453845 (Counterclockwise)
Preceding gene: 192288855
Following gene: 192288853
Centisome position: 7.91
GC content: 65.38
Gene sequence:
>780_bases GTGACTGAACGTGTAACGTTGATTACAGGCGCATCGGCCGGGATCGGTGTCGAACTGGCGCGAATTTTTGCAGACAATGC TCATCGGGTGGCCCTGGTGGCGCGGCGTGGCGACCGGCTCGAATCGCTGGCGGCTGAGATCCGTGCCAAAGGCGGGCCGG AACCGATCGTAATCGCGTGCGATCTCGGTAAGCCCGACGCGGCCGAGCAGATCATCGCGGCGCTTGCCGCTGCCGGCGTC GAGGTCGAGTACCTCGTCAACAACGCCGGATACGGACTATTCGGCCGGGCGATGGAGCTCGATCGCGAAAGCCAGCTTGG TATCATCGACGTCAATAACAGGGCGCTCACCGATCTGACGCTGCGGTTTGCCGACAGCATCGCACGGCTTCGCGGCGGCA TCCTCAATGTCGCTTCGATCGCCGGCTTCCTGCCCGGCCCCGGCATGGCGGTGTACTACGCGTCCAAGGCCTATGTGCTG TCGTTCAGCGAGGCGATGCATCAGGAGCTCGGGCCGAAGGGCGTGCGCGTCACCGCGCTGTGCCCCGGCCCGGTGCAGAC CGAGTTCCAGAACCGCGCCGGTTTCGAGCCGGGTTTCGACAGCGCCGTGCTCAACGTCACCCCCGCCGAGGTCGCACGTC AGGCCTATCAGGGACTGATGAACAACAAGCGGATCGTGCTGCCCGGCCTCGGCGTGAAGATCGTGCCGTTCCTGCTGCGG TTCTTTCCGCGCGGCTTCATCGCTGCCGCCGTCAGCGGCTTCCAGTTGCGCCGCCGCTGA
Upstream 100 bases:
>100_bases GCGAGCCGCATGGGCCCTTGCACGCTGCTTGCTTCCCGCATAAGGCCATAGCTGTTCCCCGGAGGCCGTTCGGCCCATTT TGAAACATGAGTTTCCTGTC
Downstream 100 bases:
>100_bases CGCGGGACGCCGGGACATATTCTGGCCCGGGGCTTGCTTTAAGGATTTGTCATCTTCCGCCGGACATCCTGACCGGCGGT GCGGCAATCCTGTTCGGCGC
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 259; Mature: 258
Protein sequence:
>259_residues MTERVTLITGASAGIGVELARIFADNAHRVALVARRGDRLESLAAEIRAKGGPEPIVIACDLGKPDAAEQIIAALAAAGV EVEYLVNNAGYGLFGRAMELDRESQLGIIDVNNRALTDLTLRFADSIARLRGGILNVASIAGFLPGPGMAVYYASKAYVL SFSEAMHQELGPKGVRVTALCPGPVQTEFQNRAGFEPGFDSAVLNVTPAEVARQAYQGLMNNKRIVLPGLGVKIVPFLLR FFPRGFIAAAVSGFQLRRR
Sequences:
>Translated_259_residues MTERVTLITGASAGIGVELARIFADNAHRVALVARRGDRLESLAAEIRAKGGPEPIVIACDLGKPDAAEQIIAALAAAGV EVEYLVNNAGYGLFGRAMELDRESQLGIIDVNNRALTDLTLRFADSIARLRGGILNVASIAGFLPGPGMAVYYASKAYVL SFSEAMHQELGPKGVRVTALCPGPVQTEFQNRAGFEPGFDSAVLNVTPAEVARQAYQGLMNNKRIVLPGLGVKIVPFLLR FFPRGFIAAAVSGFQLRRR >Mature_258_residues TERVTLITGASAGIGVELARIFADNAHRVALVARRGDRLESLAAEIRAKGGPEPIVIACDLGKPDAAEQIIAALAAAGVE VEYLVNNAGYGLFGRAMELDRESQLGIIDVNNRALTDLTLRFADSIARLRGGILNVASIAGFLPGPGMAVYYASKAYVLS FSEAMHQELGPKGVRVTALCPGPVQTEFQNRAGFEPGFDSAVLNVTPAEVARQAYQGLMNNKRIVLPGLGVKIVPFLLRF FPRGFIAAAVSGFQLRRR
Specific function: Catalyzes the oxidation of the hydroxyl group of serine to form 2-aminomalonate semialdehyde which is spontaneously converted into 2-aminoacetaldehyde and CO(2). Also acts on D- serine, L-glycerate, D-glycerate and 2-methyl-DL-serine. Does not act on O-me
COG id: COG0300
COG function: function code R; Short-chain dehydrogenases of various substrate specificities
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI7705855, Length=189, Percent_Identity=32.8042328042328, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI32483357, Length=192, Percent_Identity=28.125, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI33667109, Length=199, Percent_Identity=30.1507537688442, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI4557649, Length=187, Percent_Identity=34.7593582887701, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI5031737, Length=192, Percent_Identity=29.6875, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI20149619, Length=245, Percent_Identity=28.1632653061224, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI40254992, Length=192, Percent_Identity=31.25, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=28.021978021978, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI109715829, Length=195, Percent_Identity=29.7435897435897, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI157739938, Length=269, Percent_Identity=25.6505576208178, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI7705925, Length=207, Percent_Identity=32.3671497584541, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI126723750, Length=195, Percent_Identity=27.1794871794872, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI7706318, Length=192, Percent_Identity=30.2083333333333, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI142976729, Length=254, Percent_Identity=27.1653543307087, Blast_Score=66, Evalue=2e-11, Organism=Escherichia coli, GI1787820, Length=190, Percent_Identity=35.7894736842105, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI87082100, Length=189, Percent_Identity=30.1587301587302, Blast_Score=75, Evalue=6e-15, Organism=Escherichia coli, GI1786701, Length=191, Percent_Identity=27.7486910994764, Blast_Score=72, Evalue=5e-14, Organism=Escherichia coli, GI87082160, Length=221, Percent_Identity=25.3393665158371, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1787335, Length=187, Percent_Identity=26.7379679144385, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI2367365, Length=189, Percent_Identity=29.1005291005291, Blast_Score=65, Evalue=6e-12, Organism=Caenorhabditis elegans, GI71994604, Length=202, Percent_Identity=32.1782178217822, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI71994600, Length=193, Percent_Identity=32.1243523316062, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562908, Length=202, Percent_Identity=32.1782178217822, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17562906, Length=232, Percent_Identity=28.0172413793103, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI193204405, Length=202, Percent_Identity=31.1881188118812, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17562910, Length=204, Percent_Identity=26.9607843137255, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17560220, Length=201, Percent_Identity=28.8557213930348, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17559104, Length=237, Percent_Identity=27.4261603375527, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17560150, Length=197, Percent_Identity=29.9492385786802, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17560332, Length=200, Percent_Identity=29, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17562990, Length=188, Percent_Identity=29.7872340425532, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17562904, Length=203, Percent_Identity=29.064039408867, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17563726, Length=212, Percent_Identity=25.9433962264151, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI17531453, Length=191, Percent_Identity=29.3193717277487, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17551412, Length=199, Percent_Identity=27.1356783919598, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI72000259, Length=194, Percent_Identity=26.8041237113402, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI115534694, Length=212, Percent_Identity=29.2452830188679, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=195, Percent_Identity=31.7948717948718, Blast_Score=78, Evalue=2e-15, Organism=Saccharomyces cerevisiae, GI6319635, Length=188, Percent_Identity=27.6595744680851, Blast_Score=69, Evalue=1e-12, Organism=Saccharomyces cerevisiae, GI6322067, Length=192, Percent_Identity=26.0416666666667, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI28571526, Length=194, Percent_Identity=34.020618556701, Blast_Score=109, Evalue=2e-24, Organism=Drosophila melanogaster, GI21357041, Length=194, Percent_Identity=33.5051546391753, Blast_Score=108, Evalue=3e-24, Organism=Drosophila melanogaster, GI24644339, Length=193, Percent_Identity=32.1243523316062, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI23397609, Length=195, Percent_Identity=31.7948717948718, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI24584752, Length=187, Percent_Identity=33.1550802139037, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI24584744, Length=187, Percent_Identity=32.620320855615, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI28574402, Length=187, Percent_Identity=32.620320855615, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI24640442, Length=189, Percent_Identity=32.2751322751323, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI21358495, Length=251, Percent_Identity=25.8964143426295, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI161076933, Length=193, Percent_Identity=27.979274611399, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24584748, Length=193, Percent_Identity=27.979274611399, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI116007236, Length=196, Percent_Identity=28.0612244897959, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24643142, Length=188, Percent_Identity=31.9148936170213, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI21355319, Length=208, Percent_Identity=25.9615384615385, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI24644337, Length=195, Percent_Identity=33.8461538461538, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI28571387, Length=206, Percent_Identity=32.5242718446602, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24641388, Length=204, Percent_Identity=31.8627450980392, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI24580925, Length=205, Percent_Identity=30.2439024390244, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24641232, Length=202, Percent_Identity=29.7029702970297, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.276 [H]
Molecular weight: Translated: 27621; Mature: 27490
Theoretical pI: Translated: 9.44; Mature: 9.44
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTERVTLITGASAGIGVELARIFADNAHRVALVARRGDRLESLAAEIRAKGGPEPIVIAC CCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEE DLGKPDAAEQIIAALAAAGVEVEYLVNNAGYGLFGRAMELDRESQLGIIDVNNRALTDLT ECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHCCCCCCCCEEECCCCCHHHHH LRFADSIARLRGGILNVASIAGFLPGPGMAVYYASKAYVLSFSEAMHQELGPKGVRVTAL HHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECCEEEEEHHHHHHHHCCCCCEEEEEE CPGPVQTEFQNRAGFEPGFDSAVLNVTPAEVARQAYQGLMNNKRIVLPGLGVKIVPFLLR CCCCCCHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHH FFPRGFIAAAVSGFQLRRR HCCCHHHHHHHHCHHHCCC >Mature Secondary Structure TERVTLITGASAGIGVELARIFADNAHRVALVARRGDRLESLAAEIRAKGGPEPIVIAC CCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCEEEEE DLGKPDAAEQIIAALAAAGVEVEYLVNNAGYGLFGRAMELDRESQLGIIDVNNRALTDLT ECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHCCCCCCCCEEECCCCCHHHHH LRFADSIARLRGGILNVASIAGFLPGPGMAVYYASKAYVLSFSEAMHQELGPKGVRVTAL HHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECCEEEEEHHHHHHHHCCCCCEEEEEE CPGPVQTEFQNRAGFEPGFDSAVLNVTPAEVARQAYQGLMNNKRIVLPGLGVKIVPFLLR CCCCCCHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHH FFPRGFIAAAVSGFQLRRR HCCCHHHHHHHHCHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11743193; 11743194 [H]