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The map label for this gene is foxA [H]

Identifier: 192288842

GI number: 192288842

Start: 440105

End: 442381

Strand: Reverse

Name: foxA [H]

Synonym: Rpal_0411

Alternate gene names: 192288842

Gene position: 442381-440105 (Counterclockwise)

Preceding gene: 192288848

Following gene: 192288841

Centisome position: 7.7

GC content: 65.13

Gene sequence:

>2277_bases
ATGACTCCCGCCGTTCTGCCTCTCGGGCGCAATCGTCGCCTGCTGTCCTCTGTCGCCCTCGTCCCTCTGCTCTGGCCGGT
TGACGGCCTTGCGCAAACCGCCTCGGCCAATCCGCGCGGTCTCGACCCGATCGTGGTCGAGGGCCAGACCGTGCGTGCCG
CCAAGCCGCGCGCGACGGCCAATGCCGGATCGTCGCGCCAGCGCCGCGCCGCCGCGCGTCCCGTCGCGACGCCCGGCCCC
GCGCCCACTCAGCCGACGACGACCGCGGCGACCGCCCCTACCTTCAACCTCGGCACCCCGTCCTCGACCGGCAGCCGCCT
CGGCCTGACGCCGCTGCAAACGCCGGCCAGCGTGGAAGTGATTCGCGCCGAGACCATCGCCGAGCGCGGCCAGCACAACG
TCATCGACGCGGTGACGCAGAACGCCACCGGCTTCACTGCGAGCCCGCGGCCGGGAAATGGCGGCCTCGCCTTCACCACG
CGCGGCTTCACCGGCAACGGCACGGTGATGTCGCTCTACGACGGCACCCGGCTGTATGTCGGCTCGGGCACCATGACGTT
CCCATTCGATACCTGGACGGCCCAGAGCATCGAAGTGCTGCGCGGCCCGGCCTCGGTGATGTACGGCGAAGGCGCGATCG
GCGGCGCCATCAACGTGATCTCGAAGAAGCCGCTCGACGTGGCACGCAACGAAGCCGAGATCTCGCTCGACACCAACATG
AGCCGTCGCCTCGCCGTCGACTCTGGCGGGCCGATCAATCCCAATGTCAGCTACCGGCTCGCCGCGATCGGCAACATGTC
GGACGGCTGGGTCGACCGTGACAAGAACTCGAACGTCGCGGTGTCCGGCTCGGTACGGGTGCAGGCCGCCGACAACCTCG
CCTTCACGCTGAGTGAAGACTACGCCGATCGCAGCCCGTCGCGCTATTTCGGCACGCCTTTGGTGAACGGCCGGCTCGAC
GAGGCGCTACGCTTCCAGAACTACAATGTCGGCGATGCCTCGATCCGCTATCGCGACAACTGGACCCAGCTCAAGACCGA
GTGGGACGTTGCCGAAGGCGTCTCAGTGAAGAACGTCACCTATTATCTTAGCACGCACCGGCACTGGAAGGACGTCGAGA
GTTACACCTACAATCCGCTCCGCGGCAACATCGGCCGCAGCTCCTACATCGAGATCTTTCACGACCAGGAGCAGATCGGC
AACCGCTTCGACACCACCTTCAAGGGCCATGTCTTCGGCCTCGCCAACGAATTCGTAGCCGGCTTCGACGTCAACCGCAT
CGCTTTCACCCATACCAACAACTCGCCCTACGCTGGCACATCCTCGGTGCCCGCGTACAATTTCGATCCTGGCTATTTCC
TGCCGGTGAGCCCGACGCGACCGAGCTTCCATACGCTGACGACGCAATATGGCGTGTTCGCCGAGAACCGGCTCAGCCTG
ACCGACCAGCTCTCGCTGATCGGCGGCATCCGCTCCGATAATCCGACGGTGCAGCGCACCGACTTCCTCTCGCCTTCGAA
CAGTTTCGAGAAGACCTACTCGGCGCCGAGCTGGCGGGTCGGGGCGGTGTACAATCCGATCGAGAACCTCTCGATCTACG
GTCAGTATTCGACCGCGGTCGATCCGGTCACCAACCTGATCACCATGACGGGCGTAAATCGGGACTTCTCGCTGTCGACC
GGCAAGCAGGTGGAGGTCGGCATCAAGCAGCAGCTCGCCGGCGGCCGCGCCGAATGGACGCTCGCGGCGTATCACATCGT
CAAGAACAACCTGCTGGCGCGCGATCCTCAGAACCCCGCCAACACCAATCCGCTGCAGATCGGCCAGCAATCGTCGCGCG
GCATCGAAGCCTCGGCCGGCCTCAAGGTCACCGAAACCATCCGGCTCGATGCCAACGTCGCCTGGCTGCGGGCCAAATAC
GACGACTTCACCCAGGTAGTCGGCGGCCGGGCGGTGAACTACGCCGGCAACGTCCCCAACAACGTGCCGCAGATCGTCAG
CAACATCTGGGCGACCTGGGCGTTCGCGCCGGGCTGGTCGGCCAATGCCGGCGTACAGCTCGTCGGCGACACCTGGGCCG
ACGACGCCAACACGCTGGTGCGACCGGCCTATAACGTCGTCAATGCCGGGCTGATGTGGAAGCCGGACACCCGGCAGACG
CTGGCACTCCGAGTCTACAATTTGTTCGACACCGTCTACACGACATCGGGCAACACGACCATGTGGCAGCTCGGCATGCC
GCGCACGGCGGAACTGTCCTACAACGTGAAGTTCTAA

Upstream 100 bases:

>100_bases
TCGGGCGGGGTGTCCTGGTGCGAGTCGAACCGTAGCCCACAAGAAGGCTGCGGCAGACCTGTTTCGCGGTGACGTGCCAC
GTTAGCCGCGAGCCAAGAAA

Downstream 100 bases:

>100_bases
GGCGATGTCTAGCGTCGTCAGGCGCGCGAAGCGGTGGCTGTATCTCGGCCACCGTTGGCTCGGCATCGCCGGGTGTCTGC
TGTTCGCGATGTGGTTCATC

Product: TonB-dependent siderophore receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 758; Mature: 757

Protein sequence:

>758_residues
MTPAVLPLGRNRRLLSSVALVPLLWPVDGLAQTASANPRGLDPIVVEGQTVRAAKPRATANAGSSRQRRAAARPVATPGP
APTQPTTTAATAPTFNLGTPSSTGSRLGLTPLQTPASVEVIRAETIAERGQHNVIDAVTQNATGFTASPRPGNGGLAFTT
RGFTGNGTVMSLYDGTRLYVGSGTMTFPFDTWTAQSIEVLRGPASVMYGEGAIGGAINVISKKPLDVARNEAEISLDTNM
SRRLAVDSGGPINPNVSYRLAAIGNMSDGWVDRDKNSNVAVSGSVRVQAADNLAFTLSEDYADRSPSRYFGTPLVNGRLD
EALRFQNYNVGDASIRYRDNWTQLKTEWDVAEGVSVKNVTYYLSTHRHWKDVESYTYNPLRGNIGRSSYIEIFHDQEQIG
NRFDTTFKGHVFGLANEFVAGFDVNRIAFTHTNNSPYAGTSSVPAYNFDPGYFLPVSPTRPSFHTLTTQYGVFAENRLSL
TDQLSLIGGIRSDNPTVQRTDFLSPSNSFEKTYSAPSWRVGAVYNPIENLSIYGQYSTAVDPVTNLITMTGVNRDFSLST
GKQVEVGIKQQLAGGRAEWTLAAYHIVKNNLLARDPQNPANTNPLQIGQQSSRGIEASAGLKVTETIRLDANVAWLRAKY
DDFTQVVGGRAVNYAGNVPNNVPQIVSNIWATWAFAPGWSANAGVQLVGDTWADDANTLVRPAYNVVNAGLMWKPDTRQT
LALRVYNLFDTVYTTSGNTTMWQLGMPRTAELSYNVKF

Sequences:

>Translated_758_residues
MTPAVLPLGRNRRLLSSVALVPLLWPVDGLAQTASANPRGLDPIVVEGQTVRAAKPRATANAGSSRQRRAAARPVATPGP
APTQPTTTAATAPTFNLGTPSSTGSRLGLTPLQTPASVEVIRAETIAERGQHNVIDAVTQNATGFTASPRPGNGGLAFTT
RGFTGNGTVMSLYDGTRLYVGSGTMTFPFDTWTAQSIEVLRGPASVMYGEGAIGGAINVISKKPLDVARNEAEISLDTNM
SRRLAVDSGGPINPNVSYRLAAIGNMSDGWVDRDKNSNVAVSGSVRVQAADNLAFTLSEDYADRSPSRYFGTPLVNGRLD
EALRFQNYNVGDASIRYRDNWTQLKTEWDVAEGVSVKNVTYYLSTHRHWKDVESYTYNPLRGNIGRSSYIEIFHDQEQIG
NRFDTTFKGHVFGLANEFVAGFDVNRIAFTHTNNSPYAGTSSVPAYNFDPGYFLPVSPTRPSFHTLTTQYGVFAENRLSL
TDQLSLIGGIRSDNPTVQRTDFLSPSNSFEKTYSAPSWRVGAVYNPIENLSIYGQYSTAVDPVTNLITMTGVNRDFSLST
GKQVEVGIKQQLAGGRAEWTLAAYHIVKNNLLARDPQNPANTNPLQIGQQSSRGIEASAGLKVTETIRLDANVAWLRAKY
DDFTQVVGGRAVNYAGNVPNNVPQIVSNIWATWAFAPGWSANAGVQLVGDTWADDANTLVRPAYNVVNAGLMWKPDTRQT
LALRVYNLFDTVYTTSGNTTMWQLGMPRTAELSYNVKF
>Mature_757_residues
TPAVLPLGRNRRLLSSVALVPLLWPVDGLAQTASANPRGLDPIVVEGQTVRAAKPRATANAGSSRQRRAAARPVATPGPA
PTQPTTTAATAPTFNLGTPSSTGSRLGLTPLQTPASVEVIRAETIAERGQHNVIDAVTQNATGFTASPRPGNGGLAFTTR
GFTGNGTVMSLYDGTRLYVGSGTMTFPFDTWTAQSIEVLRGPASVMYGEGAIGGAINVISKKPLDVARNEAEISLDTNMS
RRLAVDSGGPINPNVSYRLAAIGNMSDGWVDRDKNSNVAVSGSVRVQAADNLAFTLSEDYADRSPSRYFGTPLVNGRLDE
ALRFQNYNVGDASIRYRDNWTQLKTEWDVAEGVSVKNVTYYLSTHRHWKDVESYTYNPLRGNIGRSSYIEIFHDQEQIGN
RFDTTFKGHVFGLANEFVAGFDVNRIAFTHTNNSPYAGTSSVPAYNFDPGYFLPVSPTRPSFHTLTTQYGVFAENRLSLT
DQLSLIGGIRSDNPTVQRTDFLSPSNSFEKTYSAPSWRVGAVYNPIENLSIYGQYSTAVDPVTNLITMTGVNRDFSLSTG
KQVEVGIKQQLAGGRAEWTLAAYHIVKNNLLARDPQNPANTNPLQIGQQSSRGIEASAGLKVTETIRLDANVAWLRAKYD
DFTQVVGGRAVNYAGNVPNNVPQIVSNIWATWAFAPGWSANAGVQLVGDTWADDANTLVRPAYNVVNAGLMWKPDTRQTL
ALRVYNLFDTVYTTSGNTTMWQLGMPRTAELSYNVKF

Specific function: Ferrioxamine binding and uptake, in association with the tonB protein. May play a role in intestinal colonization [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=739, Percent_Identity=23.0040595399188, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1787024, Length=732, Percent_Identity=23.7704918032787, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1787723, Length=671, Percent_Identity=22.354694485842, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 82240; Mature: 82108

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPAVLPLGRNRRLLSSVALVPLLWPVDGLAQTASANPRGLDPIVVEGQTVRAAKPRATA
CCCCEECCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCEEECCCEEECCCCCCCC
NAGSSRQRRAAARPVATPGPAPTQPTTTAATAPTFNLGTPSSTGSRLGLTPLQTPASVEV
CCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCEECCCCCCCCCCEEE
IRAETIAERGQHNVIDAVTQNATGFTASPRPGNGGLAFTTRGFTGNGTVMSLYDGTRLYV
EEHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCEEEE
GSGTMTFPFDTWTAQSIEVLRGPASVMYGEGAIGGAINVISKKPLDVARNEAEISLDTNM
CCCEEEECCCCCCHHHHHHHCCCCCEEECCCCCCCEEEECCCCCHHHCCCCEEEEEECCC
SRRLAVDSGGPINPNVSYRLAAIGNMSDGWVDRDKNSNVAVSGSVRVQAADNLAFTLSED
CEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEECEEEEEECCCEEEEEECC
YADRSPSRYFGTPLVNGRLDEALRFQNYNVGDASIRYRDNWTQLKTEWDVAEGVSVKNVT
CCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEECCCCEEEEEECCHHCCCEEEEEE
YYLSTHRHWKDVESYTYNPLRGNIGRSSYIEIFHDQEQIGNRFDTTFKGHVFGLANEFVA
EEEECCCCHHHHHHCCCCCCCCCCCCCCEEEEEECHHHHCCCCCCCCCCEEEEEHHHHHC
GFDVNRIAFTHTNNSPYAGTSSVPAYNFDPGYFLPVSPTRPSFHTLTTQYGVFAENRLSL
CCCCCEEEEEECCCCCCCCCCCCCCEECCCCEEEECCCCCCCCEEEEEECCEEECCCCCH
TDQLSLIGGIRSDNPTVQRTDFLSPSNSFEKTYSAPSWRVGAVYNPIENLSIYGQYSTAV
HHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHCCCCCEEECEEECCCCCCEEEEECCCHH
DPVTNLITMTGVNRDFSLSTGKQVEVGIKQQLAGGRAEWTLAAYHIVKNNLLARDPQNPA
HHHHHEEEEECCCCCEECCCCCEEEECHHHHHCCCCCEEEEEEEEHHHCCEEECCCCCCC
NTNPLQIGQQSSRGIEASAGLKVTETIRLDANVAWLRAKYDDFTQVVGGRAVNYAGNVPN
CCCCEECCCCCCCCCCCCCCCEEEEEEEECCCEEEEEECHHHHHHHHCCCEEEECCCCCC
NVPQIVSNIWATWAFAPGWSANAGVQLVGDTWADDANTLVRPAYNVVNAGLMWKPDTRQT
HHHHHHHHHHHHEECCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCEEECCCCCCE
LALRVYNLFDTVYTTSGNTTMWQLGMPRTAELSYNVKF
EEHHHHHHHHHEEECCCCCEEEEECCCCEEEEEEEECC
>Mature Secondary Structure 
TPAVLPLGRNRRLLSSVALVPLLWPVDGLAQTASANPRGLDPIVVEGQTVRAAKPRATA
CCCEECCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCEEECCCEEECCCCCCCC
NAGSSRQRRAAARPVATPGPAPTQPTTTAATAPTFNLGTPSSTGSRLGLTPLQTPASVEV
CCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCEECCCCCCCCCCEEE
IRAETIAERGQHNVIDAVTQNATGFTASPRPGNGGLAFTTRGFTGNGTVMSLYDGTRLYV
EEHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCEEEE
GSGTMTFPFDTWTAQSIEVLRGPASVMYGEGAIGGAINVISKKPLDVARNEAEISLDTNM
CCCEEEECCCCCCHHHHHHHCCCCCEEECCCCCCCEEEECCCCCHHHCCCCEEEEEECCC
SRRLAVDSGGPINPNVSYRLAAIGNMSDGWVDRDKNSNVAVSGSVRVQAADNLAFTLSED
CEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEECEEEEEECCCEEEEEECC
YADRSPSRYFGTPLVNGRLDEALRFQNYNVGDASIRYRDNWTQLKTEWDVAEGVSVKNVT
CCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEECCCCEEEEEECCHHCCCEEEEEE
YYLSTHRHWKDVESYTYNPLRGNIGRSSYIEIFHDQEQIGNRFDTTFKGHVFGLANEFVA
EEEECCCCHHHHHHCCCCCCCCCCCCCCEEEEEECHHHHCCCCCCCCCCEEEEEHHHHHC
GFDVNRIAFTHTNNSPYAGTSSVPAYNFDPGYFLPVSPTRPSFHTLTTQYGVFAENRLSL
CCCCCEEEEEECCCCCCCCCCCCCCEECCCCEEEECCCCCCCCEEEEEECCEEECCCCCH
TDQLSLIGGIRSDNPTVQRTDFLSPSNSFEKTYSAPSWRVGAVYNPIENLSIYGQYSTAV
HHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHCCCCCEEECEEECCCCCCEEEEECCCHH
DPVTNLITMTGVNRDFSLSTGKQVEVGIKQQLAGGRAEWTLAAYHIVKNNLLARDPQNPA
HHHHHEEEEECCCCCEECCCCCEEEECHHHHHCCCCCEEEEEEEEHHHCCEEECCCCCCC
NTNPLQIGQQSSRGIEASAGLKVTETIRLDANVAWLRAKYDDFTQVVGGRAVNYAGNVPN
CCCCEECCCCCCCCCCCCCCCEEEEEEEECCCEEEEEECHHHHHHHHCCCEEEECCCCCC
NVPQIVSNIWATWAFAPGWSANAGVQLVGDTWADDANTLVRPAYNVVNAGLMWKPDTRQT
HHHHHHHHHHHHEECCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCEEECCCCCCE
LALRVYNLFDTVYTTSGNTTMWQLGMPRTAELSYNVKF
EEHHHHHHHHHEEECCCCCEEEEECCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 10103258; 7642488 [H]