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The map label for this gene is yggW [C]

Identifier: 192288761

GI number: 192288761

Start: 348640

End: 349797

Strand: Reverse

Name: yggW [C]

Synonym: Rpal_0330

Alternate gene names: 192288761

Gene position: 349797-348640 (Counterclockwise)

Preceding gene: 192288762

Following gene: 192288759

Centisome position: 6.09

GC content: 67.18

Gene sequence:

>1158_bases
TTGCAGGCTAGCTCCGACCCAGCTTTTGGCGTCTACGTGCACTGGCCGTTCTGCCTGTCGAAGTGCCCGTATTGCGACTT
CAACAGCCATGTCCGCCACGCCGCGATCGACGAGGAGCGGTTCGCCCGCGCCTTCGCGCGTGAGATCGCCACCACCGCAG
AGCGAATCGGGCCGCGCCAGGTGAGCTCGATCTTTCTTGGCGGTGGCACCCCATCTCTGATGCAGCCCTCGACCGTGGCG
GCGATCCTCGACGCGATCGCCCGGCATTGGCACGTCGAACCCGGGGCCGAAGTGACGCTCGAGGCCAACCCAACCAGCGT
CGAGGCCACGCGGTTTCGCGGCTATCGGGCTGCAGGCGTCAACCGCGTGTCACTCGGCGTGCAGGCGCTGGACGACGCGT
CGCTGAAGGCGCTTGGGCGAATGCATTCGGCCGAAGAAGCCTTGAACGCGGTGGCGATCGCCAAGTCGGCGTTCGATCGT
TACTCGTTCGACCTGATCTATGCGCGGCCCGGACAGACCGCTGCGATGTGGGAAGCCGAGCTGCGCTACGCGATCGGCGA
GGCCGCAGAGCATCTGTCGCTGTATCAGCTCACCATCGAGCCCGACACGCCGTTCTATTCCCTGCACAAGGCCGGCAAGC
TGCCGACGCCGGACGAGGCCGAGGCGCGGGCGCTGTACGATGTCACGCAATCGGTCTGCGCCGAACTCGGACTCCCAGCC
TATGAGATTTCCAACCACGCCCGCCCGGGCGCGGAATGTCGGCACAACCTGATCTATTGGCGCGGCCACGAATATGCCGG
GATCGGCCCCGGCGCGCACGGCCGCCTCGACATCGGCAATGCGCGCTACGCCACCGCCACCGAGAAGCGTCCCGAGAGCT
GGCTGATGCGGGTGGAAGCCACCGGTCACGGCCTGATCGCCGACGAACACCTCACCAGCGAGGAGCGCGCCGACGAATTC
CTGCTGATGGGGCTGCGGCTTGCCGAAGGCATTGATCCGCAGCGCTATCAGTTGCTGTCCGGCCGCCCGCTCGATCCGTC
GCGGATCGCGCTGCTGCGCGAAGAGGGCGCGATCGCGGTCGATGCCGACGGCCGCTTGCGCGTGACGCAAGAGGGCTTCC
CGGTGCTCGACGCCGTGGTGGCCGATCTGGCGGCATAG

Upstream 100 bases:

>100_bases
TTCGGCGAGATGACCAGCGTCGAAAAACACGGCCTGCCGCCGCTCGGCCTCGGCCTGTCGCATCGCGCCAAGGCGTTCGT
CAAACTGGCGGAGATCTGCC

Downstream 100 bases:

>100_bases
CGGACTATGCGCCGATCTCGAGCGATGTGATGCCGTCCTCGCCGAGACCGAACCGATAGGTCAATCGCACGGGACTGCCC
GGAAAGTCGCCCGCGACGCG

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MQASSDPAFGVYVHWPFCLSKCPYCDFNSHVRHAAIDEERFARAFAREIATTAERIGPRQVSSIFLGGGTPSLMQPSTVA
AILDAIARHWHVEPGAEVTLEANPTSVEATRFRGYRAAGVNRVSLGVQALDDASLKALGRMHSAEEALNAVAIAKSAFDR
YSFDLIYARPGQTAAMWEAELRYAIGEAAEHLSLYQLTIEPDTPFYSLHKAGKLPTPDEAEARALYDVTQSVCAELGLPA
YEISNHARPGAECRHNLIYWRGHEYAGIGPGAHGRLDIGNARYATATEKRPESWLMRVEATGHGLIADEHLTSEERADEF
LLMGLRLAEGIDPQRYQLLSGRPLDPSRIALLREEGAIAVDADGRLRVTQEGFPVLDAVVADLAA

Sequences:

>Translated_385_residues
MQASSDPAFGVYVHWPFCLSKCPYCDFNSHVRHAAIDEERFARAFAREIATTAERIGPRQVSSIFLGGGTPSLMQPSTVA
AILDAIARHWHVEPGAEVTLEANPTSVEATRFRGYRAAGVNRVSLGVQALDDASLKALGRMHSAEEALNAVAIAKSAFDR
YSFDLIYARPGQTAAMWEAELRYAIGEAAEHLSLYQLTIEPDTPFYSLHKAGKLPTPDEAEARALYDVTQSVCAELGLPA
YEISNHARPGAECRHNLIYWRGHEYAGIGPGAHGRLDIGNARYATATEKRPESWLMRVEATGHGLIADEHLTSEERADEF
LLMGLRLAEGIDPQRYQLLSGRPLDPSRIALLREEGAIAVDADGRLRVTQEGFPVLDAVVADLAA
>Mature_385_residues
MQASSDPAFGVYVHWPFCLSKCPYCDFNSHVRHAAIDEERFARAFAREIATTAERIGPRQVSSIFLGGGTPSLMQPSTVA
AILDAIARHWHVEPGAEVTLEANPTSVEATRFRGYRAAGVNRVSLGVQALDDASLKALGRMHSAEEALNAVAIAKSAFDR
YSFDLIYARPGQTAAMWEAELRYAIGEAAEHLSLYQLTIEPDTPFYSLHKAGKLPTPDEAEARALYDVTQSVCAELGLPA
YEISNHARPGAECRHNLIYWRGHEYAGIGPGAHGRLDIGNARYATATEKRPESWLMRVEATGHGLIADEHLTSEERADEF
LLMGLRLAEGIDPQRYQLLSGRPLDPSRIALLREEGAIAVDADGRLRVTQEGFPVLDAVVADLAA

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=299, Percent_Identity=42.1404682274247, Blast_Score=237, Evalue=2e-62,
Organism=Escherichia coli, GI1789325, Length=326, Percent_Identity=35.8895705521472, Blast_Score=215, Evalue=3e-57,
Organism=Escherichia coli, GI87082341, Length=386, Percent_Identity=25.1295336787565, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 42076; Mature: 42076

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQASSDPAFGVYVHWPFCLSKCPYCDFNSHVRHAAIDEERFARAFAREIATTAERIGPRQ
CCCCCCCCEEEEEECHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCHH
VSSIFLGGGTPSLMQPSTVAAILDAIARHWHVEPGAEVTLEANPTSVEATRFRGYRAAGV
HHEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEHHHHCCEECCCC
NRVSLGVQALDDASLKALGRMHSAEEALNAVAIAKSAFDRYSFDLIYARPGQTAAMWEAE
CEEECCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHH
LRYAIGEAAEHLSLYQLTIEPDTPFYSLHKAGKLPTPDEAEARALYDVTQSVCAELGLPA
HHHHHHHHHHCEEEEEEEECCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCH
YEISNHARPGAECRHNLIYWRGHEYAGIGPGAHGRLDIGNARYATATEKRPESWLMRVEA
HHHCCCCCCCHHHHCCEEEEECCCCCCCCCCCCCEEECCCCEEECCCCCCCHHHEEEEEE
TGHGLIADEHLTSEERADEFLLMGLRLAEGIDPQRYQLLSGRPLDPSRIALLREEGAIAV
CCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHEEEEECCCCEEE
DADGRLRVTQEGFPVLDAVVADLAA
CCCCCEEEECCCCCHHHHHHHHHCC
>Mature Secondary Structure
MQASSDPAFGVYVHWPFCLSKCPYCDFNSHVRHAAIDEERFARAFAREIATTAERIGPRQ
CCCCCCCCEEEEEECHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCHH
VSSIFLGGGTPSLMQPSTVAAILDAIARHWHVEPGAEVTLEANPTSVEATRFRGYRAAGV
HHEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEHHHHCCEECCCC
NRVSLGVQALDDASLKALGRMHSAEEALNAVAIAKSAFDRYSFDLIYARPGQTAAMWEAE
CEEECCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHH
LRYAIGEAAEHLSLYQLTIEPDTPFYSLHKAGKLPTPDEAEARALYDVTQSVCAELGLPA
HHHHHHHHHHCEEEEEEEECCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCH
YEISNHARPGAECRHNLIYWRGHEYAGIGPGAHGRLDIGNARYATATEKRPESWLMRVEA
HHHCCCCCCCHHHHCCEEEEECCCCCCCCCCCCCEEECCCCEEECCCCCCCHHHEEEEEE
TGHGLIADEHLTSEERADEFLLMGLRLAEGIDPQRYQLLSGRPLDPSRIALLREEGAIAV
CCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHEEEEECCCCEEE
DADGRLRVTQEGFPVLDAVVADLAA
CCCCCEEEECCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]