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The map label for this gene is phoP [H]

Identifier: 192288579

GI number: 192288579

Start: 163335

End: 163700

Strand: Reverse

Name: phoP [H]

Synonym: Rpal_0146

Alternate gene names: 192288579

Gene position: 163700-163335 (Counterclockwise)

Preceding gene: 192288580

Following gene: 192288578

Centisome position: 2.85

GC content: 63.66

Gene sequence:

>366_bases
ATGGCCACGATCCTCACCGTCGACGATTCCCCCAGCATCCGCCAGATGATCAAGGTGACGCTCGAGCCGGCCGGCCACAG
CGTCGTCGAAGCCGGCGACGGCGCCCAGGGCCTGTCGAAGGCGCAGGCCACCAAGGTCGACCTCGTCATCACCGACCTCA
ACATGCCGGTGATGAACGGTCTCGAACTGATCAAGGCGCTCCGCAAGCAGCCCAACCTGGTCGGCCTGCCGATCGTGTTT
CTCACCACCGAGTCCAATGACGCGGTCAAGCAGGAGGCCAAGAGCTGCGGTGCCACCGGCTGGATCACCAAGCCGTTCAA
GCCGGAGCAACTGCTCTCTGTTGTGAGCAAGCTGGTGCGGTCATGA

Upstream 100 bases:

>100_bases
CAGAGCTCTCCGAGGTCCTTCTCAACACCATTCAGCGCGCCGGCTTCACCGGCGACGAAATAATCGACAAGCATTTCCCG
CAAAAGAAAGGTGGCTCGTA

Downstream 100 bases:

>100_bases
CCACGATCGATCCGGCAGCCGTCTTCCGCCAAGAGGCGGCCGAGCTGTTCGAGGTGCTGGAAGCGGCGCTGCTCGATCTC
GGCCAGAATCCCGACGACCG

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MATILTVDDSPSIRQMIKVTLEPAGHSVVEAGDGAQGLSKAQATKVDLVITDLNMPVMNGLELIKALRKQPNLVGLPIVF
LTTESNDAVKQEAKSCGATGWITKPFKPEQLLSVVSKLVRS

Sequences:

>Translated_121_residues
MATILTVDDSPSIRQMIKVTLEPAGHSVVEAGDGAQGLSKAQATKVDLVITDLNMPVMNGLELIKALRKQPNLVGLPIVF
LTTESNDAVKQEAKSCGATGWITKPFKPEQLLSVVSKLVRS
>Mature_120_residues
ATILTVDDSPSIRQMIKVTLEPAGHSVVEAGDGAQGLSKAQATKVDLVITDLNMPVMNGLELIKALRKQPNLVGLPIVFL
TTESNDAVKQEAKSCGATGWITKPFKPEQLLSVVSKLVRS

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788191, Length=118, Percent_Identity=35.5932203389831, Blast_Score=78, Evalue=2e-16,
Organism=Escherichia coli, GI1790863, Length=108, Percent_Identity=38.8888888888889, Blast_Score=74, Evalue=2e-15,
Organism=Escherichia coli, GI1787375, Length=117, Percent_Identity=35.042735042735, Blast_Score=72, Evalue=1e-14,
Organism=Escherichia coli, GI1788713, Length=116, Percent_Identity=38.7931034482759, Blast_Score=72, Evalue=1e-14,
Organism=Escherichia coli, GI1786599, Length=117, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=6e-14,
Organism=Escherichia coli, GI1786911, Length=106, Percent_Identity=34.9056603773585, Blast_Score=69, Evalue=8e-14,
Organism=Escherichia coli, GI1788521, Length=114, Percent_Identity=32.4561403508772, Blast_Score=65, Evalue=9e-13,
Organism=Escherichia coli, GI1788905, Length=117, Percent_Identity=37.6068376068376, Blast_Score=64, Evalue=2e-12,
Organism=Escherichia coli, GI1787473, Length=118, Percent_Identity=38.135593220339, Blast_Score=62, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 12910; Mature: 12779

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATILTVDDSPSIRQMIKVTLEPAGHSVVEAGDGAQGLSKAQATKVDLVITDLNMPVMNG
CCEEEEECCCHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHCCCEEEEEEEECCCCHHHH
LELIKALRKQPNLVGLPIVFLTTESNDAVKQEAKSCGATGWITKPFKPEQLLSVVSKLVR
HHHHHHHHHCCCEECCEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
S
C
>Mature Secondary Structure 
ATILTVDDSPSIRQMIKVTLEPAGHSVVEAGDGAQGLSKAQATKVDLVITDLNMPVMNG
CEEEEECCCHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHCCCEEEEEEEECCCCHHHH
LELIKALRKQPNLVGLPIVFLTTESNDAVKQEAKSCGATGWITKPFKPEQLLSVVSKLVR
HHHHHHHHHCCCEECCEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]