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The map label for this gene is cheA [H]

Identifier: 192288578

GI number: 192288578

Start: 161272

End: 163338

Strand: Reverse

Name: cheA [H]

Synonym: Rpal_0145

Alternate gene names: 192288578

Gene position: 163338-161272 (Counterclockwise)

Preceding gene: 192288579

Following gene: 192288577

Centisome position: 2.84

GC content: 66.18

Gene sequence:

>2067_bases
ATGACCACGATCGATCCGGCAGCCGTCTTCCGCCAAGAGGCGGCCGAGCTGTTCGAGGTGCTGGAAGCGGCGCTGCTCGA
TCTCGGCCAGAATCCCGACGACCGTGAACTGGTCGACTCCGCGTTTCGCGCCCTGCACACCATCAAGGGGTCGGGCGCGA
TGTTCGGGTTCGACAAGGTCGCCACCTTCACCCACGAATTCGAGACCGCGTTCGAGCGCGTCCGCAAGGGCGAGATCAAG
CCGACTCAGGACCTGGTCTCGGTCGCGCTGGCGGCCAAGGATTTCATCCGCGCACTGATCGAAACGCCGGACGAGGCCGA
TGCGATCATCGGCGAAGCAATCCTGGCCGATCTCAGCCGATTCGTTTCGCCGACCGAAGCCGTCGAAGCCCCCGTATCGT
TGCCCGCGCAGGAGCCTGCACCTGCTCCGGCGTCTGAGCGTCGCCAAGTCGGCTGGCATCTCCGCTTCGAATTCGACTCT
CAGATCCTGCGCAACGGGTCCAACCCGCTCGATCTGCTCGACGACCTCAGCAAGCTCGGCTCCTGCTTCGCGATGCCGCT
GACCGATGGCATTCCGTTCCTCGACGAGCTGGTGCCCGAGGATTGCTATCTGAAGTGGGACGTCTCGCTGCATTCGGATT
GCGACAAGGCCGCGATCGACGACGTCTTCATGTTCGTCCAGGACGAGATGCAGCTGTCGCTGGAGCCGCTGTTCGAAGGC
GAAACCCCGCAGCCGGTGCCGGTGCTCGAACTGCCCGACGTTTCCATTCTGCCGCCGGAGCCACCTCAGGCTGCGGAGGA
GACCAAGCCCGCCCCGCAGGCCGCGACCGCAGCGCCCGCCGCGCCGACCGTGGAGCGCCGCAGCGGCGAGCCGCGCCGCG
CCGACGATCGCGGCATCGCCACCGTCCGGGTTCAGGCCGAGCGCCTCGACGAGCTGATGGATCGGGTCGGCGAGCTGGTG
ATCGCTCAGGCGCGCCTGACCCAACTCGCAGCTTCCGGCAACGATATCTCGATCAAGCTGATCGCCGAAGAGATCGAACG
CCTCGCCTCGAGCCTGCGCGACACCACGATGGGTGCCCGCATGGTCCCGATCGGCTCGCTGTTCGGCCGCTTCCGCCGCT
TGGTGCACGATCTGTCGCGCGATCTCGGCAAGCCGGTGGAATTCATCACCTCGGGTGAGGACACCGAACTCGACAAGACG
ATGATCGAGTGCCTGGCTGATCCGCTGGTCCACCTGATCCGCAACGCGATCGACCACGGCATCGAAGCGCCGGCCGCGCG
GGTCGCCGCCGGCAAGCCGGAGCAGGGCCGGATCGAACTCGCCGCCGTACATGCCGGCGCCCAGGTCCTCGTGACCGTGA
AGGACAATGGCGGCGGGCTGAACACCGCCCGCATCCGCGCCAAGGCGGAAGAGCAGGGATTGATCGCGCCGGGGGCGACC
GCCTCCGACCAGGAAATCCATCAGTTCCTCTTCCACCCCGGCTTCTCGACCGCGCAGACCGTTTCGGCGCTGTCGGGGCG
CGGCGTCGGCATGGACGTGGTCAAGCGCACCATCGAGAACATGCGCGGGTCGATCGACCTGTCGACGGTGCCGGGTGACG
GCACCACCGTCACGCTGCGCCTGCCGCTGACGCTCGCGATCATCGAAGGTCTGCTGATCCGCGTCGGCAGCGGCCGCTAC
ATCATTCCGCTGTCCGCGGTGGAAGAGTGCGTCGAACTCACCGCCGAGGACGAGCGTTCGCGCAGCCGCAACTTCCTCAA
CGTCCGCGGCAACCTCGTGCCGTTCCTGCGCCTCCGCCAAATCTTCGACGCGGACGGTGAACCGGACCAGCACCAGAAGA
CGATCATCATTTCGACCGGCGAGACCCGCGTCGGTCTGGTGGCCGATCAGATCATCGGCAACCACCAGACTGTCATCAAA
TCACTGTCGAAGCTGCACTCCGACGTCACGATGTTCTCCGGCGCCACCATCCTGGGTGACGGAACGGCGGCGCTGATCCT
CGACGTCGTGCAGCTCGTCGGTCTCGCCCAGGCGCAATCCGAAAAGCAGATGAGCGAGGCAGCCTGA

Upstream 100 bases:

>100_bases
CGGTCAAGCAGGAGGCCAAGAGCTGCGGTGCCACCGGCTGGATCACCAAGCCGTTCAAGCCGGAGCAACTGCTCTCTGTT
GTGAGCAAGCTGGTGCGGTC

Downstream 100 bases:

>100_bases
TGAGTAGCGATCGGGTTCAGGGCGCAACCGACGGCGATGCCGACGCGATGCAGGTGGTGATGATCGGACTCGGCGACGAG
AAGTTCGCGATCGACGCCGG

Product: CheA signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 688; Mature: 687

Protein sequence:

>688_residues
MTTIDPAAVFRQEAAELFEVLEAALLDLGQNPDDRELVDSAFRALHTIKGSGAMFGFDKVATFTHEFETAFERVRKGEIK
PTQDLVSVALAAKDFIRALIETPDEADAIIGEAILADLSRFVSPTEAVEAPVSLPAQEPAPAPASERRQVGWHLRFEFDS
QILRNGSNPLDLLDDLSKLGSCFAMPLTDGIPFLDELVPEDCYLKWDVSLHSDCDKAAIDDVFMFVQDEMQLSLEPLFEG
ETPQPVPVLELPDVSILPPEPPQAAEETKPAPQAATAAPAAPTVERRSGEPRRADDRGIATVRVQAERLDELMDRVGELV
IAQARLTQLAASGNDISIKLIAEEIERLASSLRDTTMGARMVPIGSLFGRFRRLVHDLSRDLGKPVEFITSGEDTELDKT
MIECLADPLVHLIRNAIDHGIEAPAARVAAGKPEQGRIELAAVHAGAQVLVTVKDNGGGLNTARIRAKAEEQGLIAPGAT
ASDQEIHQFLFHPGFSTAQTVSALSGRGVGMDVVKRTIENMRGSIDLSTVPGDGTTVTLRLPLTLAIIEGLLIRVGSGRY
IIPLSAVEECVELTAEDERSRSRNFLNVRGNLVPFLRLRQIFDADGEPDQHQKTIIISTGETRVGLVADQIIGNHQTVIK
SLSKLHSDVTMFSGATILGDGTAALILDVVQLVGLAQAQSEKQMSEAA

Sequences:

>Translated_688_residues
MTTIDPAAVFRQEAAELFEVLEAALLDLGQNPDDRELVDSAFRALHTIKGSGAMFGFDKVATFTHEFETAFERVRKGEIK
PTQDLVSVALAAKDFIRALIETPDEADAIIGEAILADLSRFVSPTEAVEAPVSLPAQEPAPAPASERRQVGWHLRFEFDS
QILRNGSNPLDLLDDLSKLGSCFAMPLTDGIPFLDELVPEDCYLKWDVSLHSDCDKAAIDDVFMFVQDEMQLSLEPLFEG
ETPQPVPVLELPDVSILPPEPPQAAEETKPAPQAATAAPAAPTVERRSGEPRRADDRGIATVRVQAERLDELMDRVGELV
IAQARLTQLAASGNDISIKLIAEEIERLASSLRDTTMGARMVPIGSLFGRFRRLVHDLSRDLGKPVEFITSGEDTELDKT
MIECLADPLVHLIRNAIDHGIEAPAARVAAGKPEQGRIELAAVHAGAQVLVTVKDNGGGLNTARIRAKAEEQGLIAPGAT
ASDQEIHQFLFHPGFSTAQTVSALSGRGVGMDVVKRTIENMRGSIDLSTVPGDGTTVTLRLPLTLAIIEGLLIRVGSGRY
IIPLSAVEECVELTAEDERSRSRNFLNVRGNLVPFLRLRQIFDADGEPDQHQKTIIISTGETRVGLVADQIIGNHQTVIK
SLSKLHSDVTMFSGATILGDGTAALILDVVQLVGLAQAQSEKQMSEAA
>Mature_687_residues
TTIDPAAVFRQEAAELFEVLEAALLDLGQNPDDRELVDSAFRALHTIKGSGAMFGFDKVATFTHEFETAFERVRKGEIKP
TQDLVSVALAAKDFIRALIETPDEADAIIGEAILADLSRFVSPTEAVEAPVSLPAQEPAPAPASERRQVGWHLRFEFDSQ
ILRNGSNPLDLLDDLSKLGSCFAMPLTDGIPFLDELVPEDCYLKWDVSLHSDCDKAAIDDVFMFVQDEMQLSLEPLFEGE
TPQPVPVLELPDVSILPPEPPQAAEETKPAPQAATAAPAAPTVERRSGEPRRADDRGIATVRVQAERLDELMDRVGELVI
AQARLTQLAASGNDISIKLIAEEIERLASSLRDTTMGARMVPIGSLFGRFRRLVHDLSRDLGKPVEFITSGEDTELDKTM
IECLADPLVHLIRNAIDHGIEAPAARVAAGKPEQGRIELAAVHAGAQVLVTVKDNGGGLNTARIRAKAEEQGLIAPGATA
SDQEIHQFLFHPGFSTAQTVSALSGRGVGMDVVKRTIENMRGSIDLSTVPGDGTTVTLRLPLTLAIIEGLLIRVGSGRYI
IPLSAVEECVELTAEDERSRSRNFLNVRGNLVPFLRLRQIFDADGEPDQHQKTIIISTGETRVGLVADQIIGNHQTVIKS
LSKLHSDVTMFSGATILGDGTAALILDVVQLVGLAQAQSEKQMSEAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=691, Percent_Identity=34.2981186685962, Blast_Score=334, Evalue=9e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 74361; Mature: 74230

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIDPAAVFRQEAAELFEVLEAALLDLGQNPDDRELVDSAFRALHTIKGSGAMFGFDKV
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEECHHHH
ATFTHEFETAFERVRKGEIKPTQDLVSVALAAKDFIRALIETPDEADAIIGEAILADLSR
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FVSPTEAVEAPVSLPAQEPAPAPASERRQVGWHLRFEFDSQILRNGSNPLDLLDDLSKLG
HCCCHHHHCCCCCCCCCCCCCCCCHHHHCCCEEEEEEECHHHHHCCCCHHHHHHHHHHHH
SCFAMPLTDGIPFLDELVPEDCYLKWDVSLHSDCDKAAIDDVFMFVQDEMQLSLEPLFEG
HEEECCCCCCCCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
ETPQPVPVLELPDVSILPPEPPQAAEETKPAPQAATAAPAAPTVERRSGEPRRADDRGIA
CCCCCCCEEECCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCEE
TVRVQAERLDELMDRVGELVIAQARLTQLAASGNDISIKLIAEEIERLASSLRDTTMGAR
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCE
MVPIGSLFGRFRRLVHDLSRDLGKPVEFITSGEDTELDKTMIECLADPLVHLIRNAIDHG
ECHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
IEAPAARVAAGKPEQGRIELAAVHAGAQVLVTVKDNGGGLNTARIRAKAEEQGLIAPGAT
CCCCHHHHCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCCHHHEEECHHHCCCCCCCCC
ASDQEIHQFLFHPGFSTAQTVSALSGRGVGMDVVKRTIENMRGSIDLSTVPGDGTTVTLR
CCHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEE
LPLTLAIIEGLLIRVGSGRYIIPLSAVEECVELTAEDERSRSRNFLNVRGNLVPFLRLRQ
CCHHHHHHHHHHHEECCCCEEEEHHHHHHHHHHHCHHHHHHCCCEEEECCCHHHHHHHHH
IFDADGEPDQHQKTIIISTGETRVGLVADQIIGNHQTVIKSLSKLHSDVTMFSGATILGD
HHCCCCCCCCCCCEEEEECCCCEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEECC
GTAALILDVVQLVGLAQAQSEKQMSEAA
CHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTIDPAAVFRQEAAELFEVLEAALLDLGQNPDDRELVDSAFRALHTIKGSGAMFGFDKV
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEECHHHH
ATFTHEFETAFERVRKGEIKPTQDLVSVALAAKDFIRALIETPDEADAIIGEAILADLSR
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FVSPTEAVEAPVSLPAQEPAPAPASERRQVGWHLRFEFDSQILRNGSNPLDLLDDLSKLG
HCCCHHHHCCCCCCCCCCCCCCCCHHHHCCCEEEEEEECHHHHHCCCCHHHHHHHHHHHH
SCFAMPLTDGIPFLDELVPEDCYLKWDVSLHSDCDKAAIDDVFMFVQDEMQLSLEPLFEG
HEEECCCCCCCCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
ETPQPVPVLELPDVSILPPEPPQAAEETKPAPQAATAAPAAPTVERRSGEPRRADDRGIA
CCCCCCCEEECCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCEE
TVRVQAERLDELMDRVGELVIAQARLTQLAASGNDISIKLIAEEIERLASSLRDTTMGAR
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCE
MVPIGSLFGRFRRLVHDLSRDLGKPVEFITSGEDTELDKTMIECLADPLVHLIRNAIDHG
ECHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
IEAPAARVAAGKPEQGRIELAAVHAGAQVLVTVKDNGGGLNTARIRAKAEEQGLIAPGAT
CCCCHHHHCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCCHHHEEECHHHCCCCCCCCC
ASDQEIHQFLFHPGFSTAQTVSALSGRGVGMDVVKRTIENMRGSIDLSTVPGDGTTVTLR
CCHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEE
LPLTLAIIEGLLIRVGSGRYIIPLSAVEECVELTAEDERSRSRNFLNVRGNLVPFLRLRQ
CCHHHHHHHHHHHEECCCCEEEEHHHHHHHHHHHCHHHHHHCCCEEEECCCHHHHHHHHH
IFDADGEPDQHQKTIIISTGETRVGLVADQIIGNHQTVIKSLSKLHSDVTMFSGATILGD
HHCCCCCCCCCCCEEEEECCCCEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEECC
GTAALILDVVQLVGLAQAQSEKQMSEAA
CHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7623670; 11481430 [H]