Click here to switch to the map view.

The map label for this gene is aegA [H]

Identifier: 192288571

GI number: 192288571

Start: 151995

End: 153986

Strand: Reverse

Name: aegA [H]

Synonym: Rpal_0138

Alternate gene names: 192288571

Gene position: 153986-151995 (Counterclockwise)

Preceding gene: 192288572

Following gene: 192288570

Centisome position: 2.68

GC content: 66.62

Gene sequence:

>1992_bases
ATGACGCAGGTGGTGTACGGGGTCTGGGACGGCGTCGCCTATGATTCACGGGCGGCCGAGGCTCTGGCGGCGAACTACGC
GCTGGCAAACTTCGACGAGTTCGACGAGGGCAACGCGATCCGCGCTTTCATCGCCGATCGCGGGTTCTTCGTATTCGACC
CCACGGTTTCGCTGGTCGATGCGCTATTCCACTACCTGAAGGCCGCCGCCGAACAGTCCTGCGGCGCCTGTACGCCCTGC
CGGATCGGCACCGTGCTGGTCCGCGATGCGCTCGATCAGATGCGCCGCGGCCTGGACGCCGCGCTGACGCTCGACGACAT
CGTGATGCTCGGCGAGCAAATCCGGCAGACCTCGCTGTGCGGGCTGGGGCAGACCTGCGCGGTCGCGCTGCTGGCGGCGC
TGCGGGACTTTCGCGGACGGATCGAACAGGAGCTGGCGCAGCACCGGCCAATCCCGGCTCAGCACGGCATGGCCTATGTG
ACAGCGCCGTGTATCGAGGCTTGCCCCTCCAAGGTCAACGTGCCGCGCTACATCGACTACATCCGGGATGGTAAGCCGGA
GAACTCGCTCGGCGTGCTGCTGCAGAAATACCCGATGGCCGCGACCTGCGGCCGGGTCTGCGTCCGCTATTGCGAGCAGG
CGTGCCGGCGCAAATTTGTTGACGAAGCCGTCGGCATCAAGACGCTGAAGCGCTACGTCGCTGACCAGCAGAGCGGTCCA
CACGCGCTGAAATTCACCCGCGACATGATCCGCAAGCCGCTCGCCGACGGCATGCGGGTGGCGGTGGTCGGCGCTGGCCC
CGCCGGCATCTCGTGCGCCTATCATCTGCTACTGCGCGGCTATCACGTCGACGTCTTCGACAAGGCCGGCCAGGCCGGCG
GCATGGCGCAGATCGGCATTCCAAGCTACCGGCTGCCCAAGGATACGCTGGCGCTGGAGACCGACATCATCGTCGACCTC
GGCGGCCGGTTCCTGTTCGATCAGCGCCTCGGCCGCGACTTCTCGGTCGACGATCTGTTTGCGCGCGGCTATCGCGCGGT
GTTCCTGGGCCTTGGCTGTCAGCAGGGCGCCCGGCTCGGCGTCGATGGCGAAGACGCCGCACATGGCGGCTACTTCAGCG
GCATCGACTTCCTGCTCAAGGTTCACGACCACGTCGACGGCATCGCTCCGCTGGTATTGCAGGGCGAGGTGGTGGTGGTC
GGAGGCGGCAACGTCGCAATGGACTGCGTGCGTTCGGCGATCCGGCTCGGCGCCGAGAAGGTCCACGTCGTCTATCGTCG
CACCCTCGCCGACATGCCGGCCGACCCGGCCGAGATCGAAGCGGCGCGCGCCGAAGGCGTCGAATTCCATGTGCTCACCG
CGCCGGCCGAGATCGTCACCGACCACGGCAAGGTCACCGGCGTGGTGCTGACCAGGATGCAGGCGAGCGAGCCCGATGCC
GGTGGGCGGCGTTCGGTGAAGCCGGTCCCGGGCAGCGAGACATCGATGCGCTGCGACGTGCTGATCGCCGCGATCGGCCA
GCAGGTCGAGGACGGCCCGCTGATCGAGAGCGACGGCATTGCGTTCGACCGCTGGCGCTGCGTCGCGACCGACCGGGTGC
TGGCGACCTCGCGGCCGGGAGTTTTTGCCGGCGGCGATTGCGTCACCGGTCCGTCGACGCTTGTTTACGCGATGGCTGCA
GGACTGAAGGCAGCGCGCAACATCGACGATTGGATTCAACGCGGTTCGGTGCGGTTCTTCAAGCGCTCGCGGATGCGCAA
GCTGATCGCCGACAACCATATGCTGGCCAACGAGATCGTCGCAGCCCCGGTGCGCAACGCCTATCGGGTGCACAATCCCG
AAATCGATCCCGAGCTGCGCAAGCATATGTTCGGCGAAGTCGAGCAGACCATCGACGCCCGCGCCGCCTATGCGGAGACC
CAGCGCTGCATGCGCTGCTATCGCGTCTATTCCGTCGTCACCAAGCATCCGATCCCGGAAGGAGCGGCTTGA

Upstream 100 bases:

>100_bases
CGGCCGGGCCGGTTATTTCTGATCTGTGTCATCATGGGTTCAGCGCAAATCAGCTTTGATCGGCTGATCGATGCGGGCAG
TACCCTGGGGCGGGGTCGAG

Downstream 100 bases:

>100_bases
AGCGATGTGCACGCCCGATCAGGCCAGCCTGTCTGCCCGCGATCCCGCCGAGGCAACGATCACGCTCTCGATCAACGGCG
TCGCCTGCGCCGGCTTCGCC

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 663; Mature: 662

Protein sequence:

>663_residues
MTQVVYGVWDGVAYDSRAAEALAANYALANFDEFDEGNAIRAFIADRGFFVFDPTVSLVDALFHYLKAAAEQSCGACTPC
RIGTVLVRDALDQMRRGLDAALTLDDIVMLGEQIRQTSLCGLGQTCAVALLAALRDFRGRIEQELAQHRPIPAQHGMAYV
TAPCIEACPSKVNVPRYIDYIRDGKPENSLGVLLQKYPMAATCGRVCVRYCEQACRRKFVDEAVGIKTLKRYVADQQSGP
HALKFTRDMIRKPLADGMRVAVVGAGPAGISCAYHLLLRGYHVDVFDKAGQAGGMAQIGIPSYRLPKDTLALETDIIVDL
GGRFLFDQRLGRDFSVDDLFARGYRAVFLGLGCQQGARLGVDGEDAAHGGYFSGIDFLLKVHDHVDGIAPLVLQGEVVVV
GGGNVAMDCVRSAIRLGAEKVHVVYRRTLADMPADPAEIEAARAEGVEFHVLTAPAEIVTDHGKVTGVVLTRMQASEPDA
GGRRSVKPVPGSETSMRCDVLIAAIGQQVEDGPLIESDGIAFDRWRCVATDRVLATSRPGVFAGGDCVTGPSTLVYAMAA
GLKAARNIDDWIQRGSVRFFKRSRMRKLIADNHMLANEIVAAPVRNAYRVHNPEIDPELRKHMFGEVEQTIDARAAYAET
QRCMRCYRVYSVVTKHPIPEGAA

Sequences:

>Translated_663_residues
MTQVVYGVWDGVAYDSRAAEALAANYALANFDEFDEGNAIRAFIADRGFFVFDPTVSLVDALFHYLKAAAEQSCGACTPC
RIGTVLVRDALDQMRRGLDAALTLDDIVMLGEQIRQTSLCGLGQTCAVALLAALRDFRGRIEQELAQHRPIPAQHGMAYV
TAPCIEACPSKVNVPRYIDYIRDGKPENSLGVLLQKYPMAATCGRVCVRYCEQACRRKFVDEAVGIKTLKRYVADQQSGP
HALKFTRDMIRKPLADGMRVAVVGAGPAGISCAYHLLLRGYHVDVFDKAGQAGGMAQIGIPSYRLPKDTLALETDIIVDL
GGRFLFDQRLGRDFSVDDLFARGYRAVFLGLGCQQGARLGVDGEDAAHGGYFSGIDFLLKVHDHVDGIAPLVLQGEVVVV
GGGNVAMDCVRSAIRLGAEKVHVVYRRTLADMPADPAEIEAARAEGVEFHVLTAPAEIVTDHGKVTGVVLTRMQASEPDA
GGRRSVKPVPGSETSMRCDVLIAAIGQQVEDGPLIESDGIAFDRWRCVATDRVLATSRPGVFAGGDCVTGPSTLVYAMAA
GLKAARNIDDWIQRGSVRFFKRSRMRKLIADNHMLANEIVAAPVRNAYRVHNPEIDPELRKHMFGEVEQTIDARAAYAET
QRCMRCYRVYSVVTKHPIPEGAA
>Mature_662_residues
TQVVYGVWDGVAYDSRAAEALAANYALANFDEFDEGNAIRAFIADRGFFVFDPTVSLVDALFHYLKAAAEQSCGACTPCR
IGTVLVRDALDQMRRGLDAALTLDDIVMLGEQIRQTSLCGLGQTCAVALLAALRDFRGRIEQELAQHRPIPAQHGMAYVT
APCIEACPSKVNVPRYIDYIRDGKPENSLGVLLQKYPMAATCGRVCVRYCEQACRRKFVDEAVGIKTLKRYVADQQSGPH
ALKFTRDMIRKPLADGMRVAVVGAGPAGISCAYHLLLRGYHVDVFDKAGQAGGMAQIGIPSYRLPKDTLALETDIIVDLG
GRFLFDQRLGRDFSVDDLFARGYRAVFLGLGCQQGARLGVDGEDAAHGGYFSGIDFLLKVHDHVDGIAPLVLQGEVVVVG
GGNVAMDCVRSAIRLGAEKVHVVYRRTLADMPADPAEIEAARAEGVEFHVLTAPAEIVTDHGKVTGVVLTRMQASEPDAG
GRRSVKPVPGSETSMRCDVLIAAIGQQVEDGPLIESDGIAFDRWRCVATDRVLATSRPGVFAGGDCVTGPSTLVYAMAAG
LKAARNIDDWIQRGSVRFFKRSRMRKLIADNHMLANEIVAAPVRNAYRVHNPEIDPELRKHMFGEVEQTIDARAAYAETQ
RCMRCYRVYSVVTKHPIPEGAA

Specific function: Unknown

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=429, Percent_Identity=27.7389277389277, Blast_Score=174, Evalue=2e-43,
Organism=Escherichia coli, GI1788811, Length=429, Percent_Identity=36.3636363636364, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI1789606, Length=424, Percent_Identity=35.6132075471698, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI87082180, Length=421, Percent_Identity=38.2422802850356, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1789243, Length=427, Percent_Identity=32.0843091334895, Blast_Score=179, Evalue=5e-46,
Organism=Escherichia coli, GI1788468, Length=417, Percent_Identity=28.0575539568345, Blast_Score=147, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71984108, Length=470, Percent_Identity=28.2978723404255, Blast_Score=156, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17570289, Length=436, Percent_Identity=26.1467889908257, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17543860, Length=168, Percent_Identity=31.547619047619, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6320030, Length=487, Percent_Identity=25.6673511293634, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24640763, Length=439, Percent_Identity=28.246013667426, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI18858217, Length=439, Percent_Identity=28.246013667426, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI28574881, Length=430, Percent_Identity=26.7441860465116, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24665539, Length=430, Percent_Identity=26.7441860465116, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24665547, Length=431, Percent_Identity=26.6821345707657, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24665543, Length=431, Percent_Identity=26.6821345707657, Blast_Score=144, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR006006 [H]

Pfam domain/function: PF00037 Fer4; PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 72106; Mature: 71974

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQVVYGVWDGVAYDSRAAEALAANYALANFDEFDEGNAIRAFIADRGFFVFDPTVSLVD
CCEEEEEHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEECCHHHHHH
ALFHYLKAAAEQSCGACTPCRIGTVLVRDALDQMRRGLDAALTLDDIVMLGEQIRQTSLC
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
GLGQTCAVALLAALRDFRGRIEQELAQHRPIPAQHGMAYVTAPCIEACPSKVNVPRYIDY
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCEEEECHHHHHCCCCCCCHHHHHH
IRDGKPENSLGVLLQKYPMAATCGRVCVRYCEQACRRKFVDEAVGIKTLKRYVADQQSGP
HHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
HALKFTRDMIRKPLADGMRVAVVGAGPAGISCAYHLLLRGYHVDVFDKAGQAGGMAQIGI
HHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCEEHHHCCCCCCCEEEECC
PSYRLPKDTLALETDIIVDLGGRFLFDQRLGRDFSVDDLFARGYRAVFLGLGCQQGARLG
CCCCCCCHHHHEEHEEEEECCCCEEEHHHCCCCCCHHHHHHCCHHHHHEECCCCCCCCCC
VDGEDAAHGGYFSGIDFLLKVHDHVDGIAPLVLQGEVVVVGGGNVAMDCVRSAIRLGAEK
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCEEEEECCHHHHHHHHHHHHHCHHH
VHVVYRRTLADMPADPAEIEAARAEGVEFHVLTAPAEIVTDHGKVTGVVLTRMQASEPDA
HHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEECCHHHHHCCCCEEEHEEEEHHCCCCCC
GGRRSVKPVPGSETSMRCDVLIAAIGQQVEDGPLIESDGIAFDRWRCVATDRVLATSRPG
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEECCEEEEECCCEEECCCCC
VFAGGDCVTGPSTLVYAMAAGLKAARNIDDWIQRGSVRFFKRSRMRKLIADNHMLANEIV
EEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHH
AAPVRNAYRVHNPEIDPELRKHMFGEVEQTIDARAAYAETQRCMRCYRVYSVVTKHPIPE
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GAA
CCC
>Mature Secondary Structure 
TQVVYGVWDGVAYDSRAAEALAANYALANFDEFDEGNAIRAFIADRGFFVFDPTVSLVD
CEEEEEHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEECCHHHHHH
ALFHYLKAAAEQSCGACTPCRIGTVLVRDALDQMRRGLDAALTLDDIVMLGEQIRQTSLC
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
GLGQTCAVALLAALRDFRGRIEQELAQHRPIPAQHGMAYVTAPCIEACPSKVNVPRYIDY
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCEEEECHHHHHCCCCCCCHHHHHH
IRDGKPENSLGVLLQKYPMAATCGRVCVRYCEQACRRKFVDEAVGIKTLKRYVADQQSGP
HHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
HALKFTRDMIRKPLADGMRVAVVGAGPAGISCAYHLLLRGYHVDVFDKAGQAGGMAQIGI
HHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCEEHHHCCCCCCCEEEECC
PSYRLPKDTLALETDIIVDLGGRFLFDQRLGRDFSVDDLFARGYRAVFLGLGCQQGARLG
CCCCCCCHHHHEEHEEEEECCCCEEEHHHCCCCCCHHHHHHCCHHHHHEECCCCCCCCCC
VDGEDAAHGGYFSGIDFLLKVHDHVDGIAPLVLQGEVVVVGGGNVAMDCVRSAIRLGAEK
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCEEEEECCHHHHHHHHHHHHHCHHH
VHVVYRRTLADMPADPAEIEAARAEGVEFHVLTAPAEIVTDHGKVTGVVLTRMQASEPDA
HHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEECCHHHHHCCCCEEEHEEEEHHCCCCCC
GGRRSVKPVPGSETSMRCDVLIAAIGQQVEDGPLIESDGIAFDRWRCVATDRVLATSRPG
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEECCEEEEECCCEEECCCCC
VFAGGDCVTGPSTLVYAMAAGLKAARNIDDWIQRGSVRFFKRSRMRKLIADNHMLANEIV
EEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHH
AAPVRNAYRVHNPEIDPELRKHMFGEVEQTIDARAAYAETQRCMRCYRVYSVVTKHPIPE
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GAA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8955321; 9205837; 9278503 [H]