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The map label for this gene is nuoG [C]

Identifier: 192288570

GI number: 192288570

Start: 150131

End: 151990

Strand: Reverse

Name: nuoG [C]

Synonym: Rpal_0137

Alternate gene names: 192288570

Gene position: 151990-150131 (Counterclockwise)

Preceding gene: 192288571

Following gene: 192288569

Centisome position: 2.65

GC content: 66.4

Gene sequence:

>1860_bases
ATGTGCACGCCCGATCAGGCCAGCCTGTCTGCCCGCGATCCCGCCGAGGCAACGATCACGCTCTCGATCAACGGCGTCGC
CTGCGCCGGCTTCGCCAACGAGACCATCCTGTCCTGCGCGCGGCGCTACGACGTCTACATCCCGACGCTGTGCGAACTGG
AAGACATCGATCACACCCCCGGCGCCTGCCGGGTCTGCCTGGTCGAGATCCTGCAGGCCGGCAAGGACACCCCGCAGATC
GTCACCGCCTGCAACACCCCGGTGCGCGACGGCATGGAGGTGCAGACCCGCTCCAAGAAGGCGCGGGACATGCAGCGTCT
TCAGGTCGAACTGCTGATGGCCGATCATCTGCAGGATTGCGCCACCTGCATCCGGCACGGCAGTTGCGAGCTGCAGGATT
TGGCACAGTTCGTCGGGCTGCAGCAGAACCGGTTCTTCGATCGGGAACGGACCGAGTCGCGCCCGGTCGACCACAGCTCG
CCGTCGATGGTGCGCGACATGCGGCGCTGCGTCCGCTGCCAGCGCTGCGTCGCGATCTGCCGTTATCACCAGAAGATCGA
CGCGCTGGCGATCGAGGGCAGCGGGCTGGAGCGGATGGTGGCGCTGCGCGACGCCGATGGCTACCCGAATTCGGTGTGCG
TCTCCTGCGGCCAATGCGTACTGGTGTGCCCGACCGGCGCGCTCGGCGAGCGCGATGAGACCGATCGGGCGCTCGACTAC
ATCTGCGATCCGGAGGTCGTCACCGTGGTGCAGTTCGCCCCTGCGGTGCGGGTGGCGTTCGGCGAGGAATTCGGCCTGCC
TGCCGGCACCAATGTCGAAGGCCAGATCATCGCCGCCTGCCGCAAGCTCGGCGTCGATGTGGTGCTCGATACCAATTTCG
CCGCCGACGTGGTGATCATGGAGGAGGGTGCCGAACTGCTGGCGCGGCTGAAGCAGGGGCGGCGCCCGACCTTCACGTCC
TGCTGCCCGGCCTGGATCAACTTCGCCGAGATCCACTATCCGGACGTGCTGCCGCTGCTGTCCTCGACCAAGTCGCCGCA
GCAGGTACTGTCGACGATCGCCAAGAGCTATCTGCCGGCACAGCTCGGCGTTCCGGCCGAGCGTATCCGGGTGATTTCGA
TCATGCCGTGCATCGCCAAGAAGGACGAGGCGGTGCGGCCGCAGATGGTCCATGACGGGCAGCCCGAAACCGACCTGGTG
CTGACCACGCGCGAATTCGCCCGGCTGCTGCGGCGCGAGGGCATCGATCTGAAGGATCTGCCGTCGTCGCAGTTCGATCG
TCCGTTCCTCAGCGCCTATTCCGGTGCCGGTGCCATCTTCGGCACCACCGGCGGCGTGATGGAAGCCGCGGTGCGGACCA
TCTACGCGCTGGTGAACGGCCGCGAACTGGATCGGATCGAGCTGACGCAGCTGCGCGGCTTCGAAGGGCTGCGCGAGGCA
ACTGTCGATCTCGGCGGCCCGGTCGGCGAGGTCAAGGTCGCGATGGTTCACGGCCTCGGCGACACGCGCCGGCTGGTGGA
ATCGGTGCTGAGCGGCGAAGCCAACTACGATTTCATCGAGGTGATGGCCTGTCCGGGCGGCTGCGTCGACGGCGGCGGGT
CGCTGCGTTCGAAGAAGGCGTATCTGCCGCTGGCGCTGAAGCGCCGCGAGACCATCTACAATGTCGACCGCGCCGCCAAG
GTCCGGCAGTCGCACAACAATCCGCAGGTGCAGGTGCTGTACCGCGAACTGCTGCAGGCGCCCAATTCGGAAATCGCGCA
TCGGCTGCTGCACACCCACTACGCGTCGCGCAAACGCGAGCTGCAGCACACCGTGAAGGAGATCTGGGACGATCTCACCA
TGAGCACGATCCTGTACTGA

Upstream 100 bases:

>100_bases
GCCCGCGCCGCCTATGCGGAGACCCAGCGCTGCATGCGCTGCTATCGCGTCTATTCCGTCGTCACCAAGCATCCGATCCC
GGAAGGAGCGGCTTGAAGCG

Downstream 100 bases:

>100_bases
CGGGGAGCGCAGGAGATGTCGCCGCCACAGCATCTGATCCCCACTCGGCGCGATGTGGTGCGCGGCCTTGCGGCGCTGCC
GGCGCTGGGGTTGACGCGGA

Product: hydrogenase, Fe-only

Products: NA

Alternate protein names: CpI; Fe-only hydrogenase; [Fe] hydrogenase [H]

Number of amino acids: Translated: 619; Mature: 619

Protein sequence:

>619_residues
MCTPDQASLSARDPAEATITLSINGVACAGFANETILSCARRYDVYIPTLCELEDIDHTPGACRVCLVEILQAGKDTPQI
VTACNTPVRDGMEVQTRSKKARDMQRLQVELLMADHLQDCATCIRHGSCELQDLAQFVGLQQNRFFDRERTESRPVDHSS
PSMVRDMRRCVRCQRCVAICRYHQKIDALAIEGSGLERMVALRDADGYPNSVCVSCGQCVLVCPTGALGERDETDRALDY
ICDPEVVTVVQFAPAVRVAFGEEFGLPAGTNVEGQIIAACRKLGVDVVLDTNFAADVVIMEEGAELLARLKQGRRPTFTS
CCPAWINFAEIHYPDVLPLLSSTKSPQQVLSTIAKSYLPAQLGVPAERIRVISIMPCIAKKDEAVRPQMVHDGQPETDLV
LTTREFARLLRREGIDLKDLPSSQFDRPFLSAYSGAGAIFGTTGGVMEAAVRTIYALVNGRELDRIELTQLRGFEGLREA
TVDLGGPVGEVKVAMVHGLGDTRRLVESVLSGEANYDFIEVMACPGGCVDGGGSLRSKKAYLPLALKRRETIYNVDRAAK
VRQSHNNPQVQVLYRELLQAPNSEIAHRLLHTHYASRKRELQHTVKEIWDDLTMSTILY

Sequences:

>Translated_619_residues
MCTPDQASLSARDPAEATITLSINGVACAGFANETILSCARRYDVYIPTLCELEDIDHTPGACRVCLVEILQAGKDTPQI
VTACNTPVRDGMEVQTRSKKARDMQRLQVELLMADHLQDCATCIRHGSCELQDLAQFVGLQQNRFFDRERTESRPVDHSS
PSMVRDMRRCVRCQRCVAICRYHQKIDALAIEGSGLERMVALRDADGYPNSVCVSCGQCVLVCPTGALGERDETDRALDY
ICDPEVVTVVQFAPAVRVAFGEEFGLPAGTNVEGQIIAACRKLGVDVVLDTNFAADVVIMEEGAELLARLKQGRRPTFTS
CCPAWINFAEIHYPDVLPLLSSTKSPQQVLSTIAKSYLPAQLGVPAERIRVISIMPCIAKKDEAVRPQMVHDGQPETDLV
LTTREFARLLRREGIDLKDLPSSQFDRPFLSAYSGAGAIFGTTGGVMEAAVRTIYALVNGRELDRIELTQLRGFEGLREA
TVDLGGPVGEVKVAMVHGLGDTRRLVESVLSGEANYDFIEVMACPGGCVDGGGSLRSKKAYLPLALKRRETIYNVDRAAK
VRQSHNNPQVQVLYRELLQAPNSEIAHRLLHTHYASRKRELQHTVKEIWDDLTMSTILY
>Mature_619_residues
MCTPDQASLSARDPAEATITLSINGVACAGFANETILSCARRYDVYIPTLCELEDIDHTPGACRVCLVEILQAGKDTPQI
VTACNTPVRDGMEVQTRSKKARDMQRLQVELLMADHLQDCATCIRHGSCELQDLAQFVGLQQNRFFDRERTESRPVDHSS
PSMVRDMRRCVRCQRCVAICRYHQKIDALAIEGSGLERMVALRDADGYPNSVCVSCGQCVLVCPTGALGERDETDRALDY
ICDPEVVTVVQFAPAVRVAFGEEFGLPAGTNVEGQIIAACRKLGVDVVLDTNFAADVVIMEEGAELLARLKQGRRPTFTS
CCPAWINFAEIHYPDVLPLLSSTKSPQQVLSTIAKSYLPAQLGVPAERIRVISIMPCIAKKDEAVRPQMVHDGQPETDLV
LTTREFARLLRREGIDLKDLPSSQFDRPFLSAYSGAGAIFGTTGGVMEAAVRTIYALVNGRELDRIELTQLRGFEGLREA
TVDLGGPVGEVKVAMVHGLGDTRRLVESVLSGEANYDFIEVMACPGGCVDGGGSLRSKKAYLPLALKRRETIYNVDRAAK
VRQSHNNPQVQVLYRELLQAPNSEIAHRLLHTHYASRKRELQHTVKEIWDDLTMSTILY

Specific function: Ndh-1 Shuttles Electrons From NADH, Via Fmn And Iron- Sulfur (Fe-S) Centers, To Quinones In The Respiratory Chain. The Immediate Electron Acceptor For The Enzyme In This Species Is Believed To Be Ubiquinone. Couples The Redox Reaction To Proton Translocat

COG id: COG4624

COG function: function code R; Iron only hydrogenase large subunit, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI11968051, Length=402, Percent_Identity=31.3432835820896, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI6912524, Length=423, Percent_Identity=27.8959810874704, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI134284357, Length=381, Percent_Identity=28.6089238845144, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI84452151, Length=392, Percent_Identity=28.5714285714286, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI14165461, Length=461, Percent_Identity=27.3318872017354, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI33519475, Length=220, Percent_Identity=29.5454545454545, Blast_Score=100, Evalue=7e-21,
Organism=Escherichia coli, GI145693161, Length=255, Percent_Identity=26.6666666666667, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71995015, Length=337, Percent_Identity=30.5637982195846, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32566231, Length=195, Percent_Identity=28.7179487179487, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17565758, Length=198, Percent_Identity=28.2828282828283, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193209088, Length=198, Percent_Identity=28.2828282828283, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324089, Length=352, Percent_Identity=23.5795454545455, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI116007470, Length=445, Percent_Identity=27.4157303370787, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI116007466, Length=445, Percent_Identity=27.4157303370787, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI116007464, Length=421, Percent_Identity=27.5534441805226, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI116007468, Length=421, Percent_Identity=27.5534441805226, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI116007462, Length=307, Percent_Identity=28.9902280130293, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24640559, Length=244, Percent_Identity=28.6885245901639, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24640557, Length=244, Percent_Identity=28.6885245901639, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR009016
- InterPro:   IPR004108
- InterPro:   IPR003149
- InterPro:   IPR013352
- InterPro:   IPR001041 [H]

Pfam domain/function: PF02906 Fe_hyd_lg_C; PF02256 Fe_hyd_SSU [H]

EC number: =1.12.7.2 [H]

Molecular weight: Translated: 68253; Mature: 68253

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCTPDQASLSARDPAEATITLSINGVACAGFANETILSCARRYDVYIPTLCELEDIDHTP
CCCCCCCCCCCCCCCCEEEEEEECCEEECCCCHHHHHHHHHHCCCCCCCHHCCCCCCCCC
GACRVCLVEILQAGKDTPQIVTACNTPVRDGMEVQTRSKKARDMQRLQVELLMADHLQDC
HHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATCIRHGSCELQDLAQFVGLQQNRFFDRERTESRPVDHSSPSMVRDMRRCVRCQRCVAIC
HHHHHCCCCCHHHHHHHHCCHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RYHQKIDALAIEGSGLERMVALRDADGYPNSVCVSCGQCVLVCPTGALGERDETDRALDY
HHHHHHHEEEECCCCHHHHHEEECCCCCCCHHHHCCCCEEEEECCCCCCCCCCHHHHHHH
ICDPEVVTVVQFAPAVRVAFGEEFGLPAGTNVEGQIIAACRKLGVDVVLDTNFAADVVIM
CCCCCHHHHHHHCCHHHEECCHHCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCEEEEEE
EEGAELLARLKQGRRPTFTSCCPAWINFAEIHYPDVLPLLSSTKSPQQVLSTIAKSYLPA
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHCCH
QLGVPAERIRVISIMPCIAKKDEAVRPQMVHDGQPETDLVLTTREFARLLRREGIDLKDL
HCCCCHHHEEEHHHHHHHCCCCCCCCCCHHCCCCCCCCEEEEHHHHHHHHHHCCCCCCCC
PSSQFDRPFLSAYSGAGAIFGTTGGVMEAAVRTIYALVNGRELDRIELTQLRGFEGLREA
CCCCCCCHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHH
TVDLGGPVGEVKVAMVHGLGDTRRLVESVLSGEANYDFIEVMACPGGCVDGGGSLRSKKA
HHHCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCC
YLPLALKRRETIYNVDRAAKVRQSHNNPQVQVLYRELLQAPNSEIAHRLLHTHYASRKRE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LQHTVKEIWDDLTMSTILY
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MCTPDQASLSARDPAEATITLSINGVACAGFANETILSCARRYDVYIPTLCELEDIDHTP
CCCCCCCCCCCCCCCCEEEEEEECCEEECCCCHHHHHHHHHHCCCCCCCHHCCCCCCCCC
GACRVCLVEILQAGKDTPQIVTACNTPVRDGMEVQTRSKKARDMQRLQVELLMADHLQDC
HHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATCIRHGSCELQDLAQFVGLQQNRFFDRERTESRPVDHSSPSMVRDMRRCVRCQRCVAIC
HHHHHCCCCCHHHHHHHHCCHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RYHQKIDALAIEGSGLERMVALRDADGYPNSVCVSCGQCVLVCPTGALGERDETDRALDY
HHHHHHHEEEECCCCHHHHHEEECCCCCCCHHHHCCCCEEEEECCCCCCCCCCHHHHHHH
ICDPEVVTVVQFAPAVRVAFGEEFGLPAGTNVEGQIIAACRKLGVDVVLDTNFAADVVIM
CCCCCHHHHHHHCCHHHEECCHHCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCEEEEEE
EEGAELLARLKQGRRPTFTSCCPAWINFAEIHYPDVLPLLSSTKSPQQVLSTIAKSYLPA
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHCCH
QLGVPAERIRVISIMPCIAKKDEAVRPQMVHDGQPETDLVLTTREFARLLRREGIDLKDL
HCCCCHHHEEEHHHHHHHCCCCCCCCCCHHCCCCCCCCEEEEHHHHHHHHHHCCCCCCCC
PSSQFDRPFLSAYSGAGAIFGTTGGVMEAAVRTIYALVNGRELDRIELTQLRGFEGLREA
CCCCCCCHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHH
TVDLGGPVGEVKVAMVHGLGDTRRLVESVLSGEANYDFIEVMACPGGCVDGGGSLRSKKA
HHHCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCC
YLPLALKRRETIYNVDRAAKVRQSHNNPQVQVLYRELLQAPNSEIAHRLLHTHYASRKRE
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LQHTVKEIWDDLTMSTILY
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1911757; 9836629; 10529166 [H]