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The map label for this gene is prpC [H]

Identifier: 190895262

GI number: 190895262

Start: 1026088

End: 1026858

Strand: Reverse

Name: prpC [H]

Synonym: RHECIAT_PC0000935

Alternate gene names: 190895262

Gene position: 1026858-1026088 (Counterclockwise)

Preceding gene: 190895264

Following gene: 190895261

Centisome position: 94.08

GC content: 62.78

Gene sequence:

>771_bases
ATGACCCCGGAATATCCCGAGAGTCCCTCGACGCGCGTGCCGAAGTGGCGGGGCAGGCCGCAAGGGGCCGGGCTGAGCCA
CACGGGTCATGTTCGCAAACGCAACGAGGACGCAATACTCATCGATCCCACAGGCGTGCTTTGGGCCGTTGCCGACGGTA
TGGGTGGCTACGGGCATGGCGACGTAGCGGCTGGCCTGGTGATCGAGCATCTAGCCCTGCTTCCCCATGAGCCAATTTCG
AGCGCCGATCTGGTGGGCGCGCTCGAGGCTGCCAATTCCGCCATTCGGCGATGGGCAACCTCGGCCGACGTGGCACAGAT
GGGTGCAACCGTGGTGGCCGCGCTTCTGCAGGGCAGTGCTCTTTCGCTTGCATGGGCCGGCGACAGCCGTGCCTATCGCT
GGCGGGATCGGGAATTGCTACAGCTGACGCGCGATCATTCGGTCGTGCAGGAGCTTCTCGACGATGGGCGCCTTTCTCCC
GCGGCGGCCTGGCAGCACCCGCAAGCGCATGTTGTAACACGCGCAATTGGAGCGTCCGATCATCTTGTCGTCGAAACCGC
TGAAGTTTCGCTTTATCCGGGGGATGTCCTCATTCTTTGCTCCGACGGGCTAACCGACTGTGTGGCGGACGCCGAGATCG
CTGCCCTTACGAACGCCCTTTCAACGCCGGCGGCGACCTGTCAGCGATTGATCGACGCTGCTCTCGATAACGGTGCCCCG
GACAACGTCTCGGTGATTGTCGTCCAGATTGATGGAGCTGCGATATCTTGA

Upstream 100 bases:

>100_bases
AATGTTTCGCCTGGTCAAAAAATTACTATAGGATGATCGTGGGTGCAACCGCTTCCATGGCGGTCCTCACGGCGGAGCGA
ATGATGAGGTTCTTCCGGTC

Downstream 100 bases:

>100_bases
GGCAAATGAATGCCATCGCGGCCGTCGTCATCGGCATGAGCATCATTCTCGCGGCCATCATCTTTGCGTTTGTCGGAAAC
CTCTTGCAAGATACGGAGCG

Product: putative phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MTPEYPESPSTRVPKWRGRPQGAGLSHTGHVRKRNEDAILIDPTGVLWAVADGMGGYGHGDVAAGLVIEHLALLPHEPIS
SADLVGALEAANSAIRRWATSADVAQMGATVVAALLQGSALSLAWAGDSRAYRWRDRELLQLTRDHSVVQELLDDGRLSP
AAAWQHPQAHVVTRAIGASDHLVVETAEVSLYPGDVLILCSDGLTDCVADAEIAALTNALSTPAATCQRLIDAALDNGAP
DNVSVIVVQIDGAAIS

Sequences:

>Translated_256_residues
MTPEYPESPSTRVPKWRGRPQGAGLSHTGHVRKRNEDAILIDPTGVLWAVADGMGGYGHGDVAAGLVIEHLALLPHEPIS
SADLVGALEAANSAIRRWATSADVAQMGATVVAALLQGSALSLAWAGDSRAYRWRDRELLQLTRDHSVVQELLDDGRLSP
AAAWQHPQAHVVTRAIGASDHLVVETAEVSLYPGDVLILCSDGLTDCVADAEIAALTNALSTPAATCQRLIDAALDNGAP
DNVSVIVVQIDGAAIS
>Mature_255_residues
TPEYPESPSTRVPKWRGRPQGAGLSHTGHVRKRNEDAILIDPTGVLWAVADGMGGYGHGDVAAGLVIEHLALLPHEPISS
ADLVGALEAANSAIRRWATSADVAQMGATVVAALLQGSALSLAWAGDSRAYRWRDRELLQLTRDHSVVQELLDDGRLSPA
AAWQHPQAHVVTRAIGASDHLVVETAEVSLYPGDVLILCSDGLTDCVADAEIAALTNALSTPAATCQRLIDAALDNGAPD
NVSVIVVQIDGAAIS

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 26833; Mature: 26702

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPEYPESPSTRVPKWRGRPQGAGLSHTGHVRKRNEDAILIDPTGVLWAVADGMGGYGHG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCEEEECCCCEEEEEECCCCCCCCH
DVAAGLVIEHLALLPHEPISSADLVGALEAANSAIRRWATSADVAQMGATVVAALLQGSA
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCE
LSLAWAGDSRAYRWRDRELLQLTRDHSVVQELLDDGRLSPAAAWQHPQAHVVTRAIGASD
EEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHCCCCC
HLVVETAEVSLYPGDVLILCSDGLTDCVADAEIAALTNALSTPAATCQRLIDAALDNGAP
CEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
DNVSVIVVQIDGAAIS
CCEEEEEEEECCCCCC
>Mature Secondary Structure 
TPEYPESPSTRVPKWRGRPQGAGLSHTGHVRKRNEDAILIDPTGVLWAVADGMGGYGHG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCEEEECCCCEEEEEECCCCCCCCH
DVAAGLVIEHLALLPHEPISSADLVGALEAANSAIRRWATSADVAQMGATVVAALLQGSA
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCE
LSLAWAGDSRAYRWRDRELLQLTRDHSVVQELLDDGRLSPAAAWQHPQAHVVTRAIGASD
EEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHCCCCC
HLVVETAEVSLYPGDVLILCSDGLTDCVADAEIAALTNALSTPAATCQRLIDAALDNGAP
CEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
DNVSVIVVQIDGAAIS
CCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]