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The map label for this gene is lspL [H]

Identifier: 190895176

GI number: 190895176

Start: 930550

End: 931581

Strand: Reverse

Name: lspL [H]

Synonym: RHECIAT_PC0000849

Alternate gene names: 190895176

Gene position: 931581-930550 (Counterclockwise)

Preceding gene: 190895177

Following gene: 190895175

Centisome position: 85.35

GC content: 52.71

Gene sequence:

>1032_bases
ATGCGATTTCTAGTAACTGGAACTGGGGGCTTCATAGGCTTTCACCTTGCAAGACGCCTATTGGAGGAAGGTCATTCCGT
GACGGGATTCGACGGGATGACGCGGTATTACGACGTTTCTCTCAAGGAACGGCGGCACGCGATCCTATCCAGCTACGGCA
ACTTCCAGCCAATCATCGCAATGCTGGAGAACCGCGAGCGATTGACAGAAGCATTCAATATAGCTCAGCCCGATGTCGTC
GTTCACTTGGCCGCTCAAGCAGGCGTGAGATATAGCCTGGAGAATCCTGATGCATACATCGGATCGAATTTGGTGGGATC
GTGGAACGTACTCGATCTGTGTCGGCAGTTTCGACCCAATCACCTATTGCTGGCATCGACGTCGTCGATTTATGGCGCGA
ACAGCAAGATTCCATTCGAGGAATCGGATAAAGCCGACGAGCCGTTGACCCTTTACGCCGCGTCAAAAAAATCCATGGAA
GTAATGGCGCACAGCCAATCGCATCTTCATAAGATCCCAACCACCGCATTTAGGTTTTTCACAGTTTACGGCCCTTGGGG
TCGGCCGGATATGGCACTCTTCAAATTCGTAAGTGCCATACTCAACGGCAAGCCGATCGATGTTTACGGGCATGGACAAA
TGTCTCGAGATTTCACCTATATCGACGATCTCGTCGAAGCGATTGTCCGCCTCATACCCGTGATTCCGCAGGCCTCAGCG
CCGGCGGATGCCGCGATAGACAACGTATCAATGCAAGCACCGTTCCGCATTGTGAACATCGGGGGAGGGCAACCGGTTGG
CCTGGAAACATTTATCGAAACTGTAGAGCAGGCTCTGGGACAGAAGGCGTTGCGCAATATGCTACCTATGCAACAGGGCG
ATGTGCCTCGTACCTTTGCGGCACCTGAGCTTCTTCGGGCTTTGACGGGCTACACGCCGCAGACACCCGTAGCTGAAGGT
GTTCGGCGCTTTGTTGAATGGTATCGGCAAGCTTTTGAATTGAAAACCAAAGTTGTGGAACCGGTCGAGTAG

Upstream 100 bases:

>100_bases
TTGTTGAAAGATAGCGCACCCGAATTATTCACCCAGGTGTGCTTAGTGTCGATGTGGATGCTAGGCAAATGTGCCGCAGA
TAAAGAGTAGATAAAGAGAT

Downstream 100 bases:

>100_bases
CGCCTTGCTGAAATTCGTCGTTGCGACCCTATTTGCGATCAACATGATGCTTGCCGTTGTGCTGGTGAGGCTGTCGGTTG
GAGGGCTTCCCGTACGATTG

Product: putative nucleoside-diphosphate-sugar epimerase

Products: NA

Alternate protein names: UDP-glucuronic acid epimerase [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MRFLVTGTGGFIGFHLARRLLEEGHSVTGFDGMTRYYDVSLKERRHAILSSYGNFQPIIAMLENRERLTEAFNIAQPDVV
VHLAAQAGVRYSLENPDAYIGSNLVGSWNVLDLCRQFRPNHLLLASTSSIYGANSKIPFEESDKADEPLTLYAASKKSME
VMAHSQSHLHKIPTTAFRFFTVYGPWGRPDMALFKFVSAILNGKPIDVYGHGQMSRDFTYIDDLVEAIVRLIPVIPQASA
PADAAIDNVSMQAPFRIVNIGGGQPVGLETFIETVEQALGQKALRNMLPMQQGDVPRTFAAPELLRALTGYTPQTPVAEG
VRRFVEWYRQAFELKTKVVEPVE

Sequences:

>Translated_343_residues
MRFLVTGTGGFIGFHLARRLLEEGHSVTGFDGMTRYYDVSLKERRHAILSSYGNFQPIIAMLENRERLTEAFNIAQPDVV
VHLAAQAGVRYSLENPDAYIGSNLVGSWNVLDLCRQFRPNHLLLASTSSIYGANSKIPFEESDKADEPLTLYAASKKSME
VMAHSQSHLHKIPTTAFRFFTVYGPWGRPDMALFKFVSAILNGKPIDVYGHGQMSRDFTYIDDLVEAIVRLIPVIPQASA
PADAAIDNVSMQAPFRIVNIGGGQPVGLETFIETVEQALGQKALRNMLPMQQGDVPRTFAAPELLRALTGYTPQTPVAEG
VRRFVEWYRQAFELKTKVVEPVE
>Mature_343_residues
MRFLVTGTGGFIGFHLARRLLEEGHSVTGFDGMTRYYDVSLKERRHAILSSYGNFQPIIAMLENRERLTEAFNIAQPDVV
VHLAAQAGVRYSLENPDAYIGSNLVGSWNVLDLCRQFRPNHLLLASTSSIYGANSKIPFEESDKADEPLTLYAASKKSME
VMAHSQSHLHKIPTTAFRFFTVYGPWGRPDMALFKFVSAILNGKPIDVYGHGQMSRDFTYIDDLVEAIVRLIPVIPQASA
PADAAIDNVSMQAPFRIVNIGGGQPVGLETFIETVEQALGQKALRNMLPMQQGDVPRTFAAPELLRALTGYTPQTPVAEG
VRRFVEWYRQAFELKTKVVEPVE

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI7657641, Length=347, Percent_Identity=24.7838616714697, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI42516563, Length=340, Percent_Identity=26.1764705882353, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI56237023, Length=351, Percent_Identity=23.3618233618234, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI56118217, Length=351, Percent_Identity=23.3618233618234, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI189083684, Length=351, Percent_Identity=23.3618233618234, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1788353, Length=368, Percent_Identity=27.7173913043478, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI48994969, Length=354, Percent_Identity=26.8361581920904, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1786974, Length=320, Percent_Identity=22.8125, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17539532, Length=363, Percent_Identity=26.1707988980716, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71982038, Length=352, Percent_Identity=23.2954545454545, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71982035, Length=352, Percent_Identity=23.8636363636364, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17568069, Length=333, Percent_Identity=24.3243243243243, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356223, Length=347, Percent_Identity=25.0720461095101, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI19923002, Length=351, Percent_Identity=21.9373219373219, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.12 [H]

Molecular weight: Translated: 38192; Mature: 38192

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLVTGTGGFIGFHLARRLLEEGHSVTGFDGMTRYYDVSLKERRHAILSSYGNFQPIIA
CEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHEECHHHHHHHHHHHHCCCHHHHHH
MLENRERLTEAFNIAQPDVVVHLAAQAGVRYSLENPDAYIGSNLVGSWNVLDLCRQFRPN
HHHHHHHHHHHHCCCCCHHEEEEEHHCCCEEECCCCCHHHCCCCCCCCCHHHHHHHCCCC
HLLLASTSSIYGANSKIPFEESDKADEPLTLYAASKKSMEVMAHSQSHLHKIPTTAFRFF
EEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCHHHEEEE
TVYGPWGRPDMALFKFVSAILNGKPIDVYGHGQMSRDFTYIDDLVEAIVRLIPVIPQASA
EEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
PADAAIDNVSMQAPFRIVNIGGGQPVGLETFIETVEQALGQKALRNMLPMQQGDVPRTFA
CCHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
APELLRALTGYTPQTPVAEGVRRFVEWYRQAFELKTKVVEPVE
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRFLVTGTGGFIGFHLARRLLEEGHSVTGFDGMTRYYDVSLKERRHAILSSYGNFQPIIA
CEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHEECHHHHHHHHHHHHCCCHHHHHH
MLENRERLTEAFNIAQPDVVVHLAAQAGVRYSLENPDAYIGSNLVGSWNVLDLCRQFRPN
HHHHHHHHHHHHCCCCCHHEEEEEHHCCCEEECCCCCHHHCCCCCCCCCHHHHHHHCCCC
HLLLASTSSIYGANSKIPFEESDKADEPLTLYAASKKSMEVMAHSQSHLHKIPTTAFRFF
EEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCHHHEEEE
TVYGPWGRPDMALFKFVSAILNGKPIDVYGHGQMSRDFTYIDDLVEAIVRLIPVIPQASA
EEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
PADAAIDNVSMQAPFRIVNIGGGQPVGLETFIETVEQALGQKALRNMLPMQQGDVPRTFA
CCHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
APELLRALTGYTPQTPVAEGVRRFVEWYRQAFELKTKVVEPVE
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9765575; 11481430 [H]