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The map label for this gene is dxs [C]

Identifier: 190895096

GI number: 190895096

Start: 822857

End: 823894

Strand: Reverse

Name: dxs [C]

Synonym: RHECIAT_PC0000766

Alternate gene names: 190895096

Gene position: 823894-822857 (Counterclockwise)

Preceding gene: 190895097

Following gene: 190895095

Centisome position: 75.48

GC content: 63.39

Gene sequence:

>1038_bases
ATGAGGCGTTCCAAGTACATCCGGCCTGCCCATCTTGAAAGCGGCATCGACAAGCCCCGCCTAACGACGTCGGCGATGAT
CGCATCGATTGCCGGTCCCGATCAGCCGACGAGGCCGGCACCCTTCGGCAACGCGCTTGCCGCCCTGGCGCGGAATGACG
AGCGTATTGTCGGCATGTCCGCCGACCTTGCGAAATACACGGACCTTCATGTGTTCCGTGCTGCGCATCCCGACCGCTTC
TACCAGATGGGAATGGCGGAACAGCTGCTGATGATGTCGGCGGCGGGCATGGCGCGCGAAGGCTTTCAGCCTTGGGTAAC
GACATATGCCGTCTTCGCCTCCCGGCGGGCCTACGACTTCATCTGCCTGGCGATTGCCGAGGAGATGCTTGATGTGAAGA
TTGTCTGCGCCCTTCCGGGCTTGACGACGGGATATGGGCCGAGCCACCAGGCGACGGAAGATCTCGCAATGTTCCGCGGC
ATGCCGAACCTGACGATCGTCGATCCGTGCGACGCGAGCGAGATCGAGCAAGCGGTTCCGGCGATCGCCGCCCATAAAGG
GCCGGTCTACATGCGCCTGCTACGCGGCAACGTTCCGCTGGTTCTGGAGGAATACGGCTACAAATTCGAACTCGGCAAGG
CCAAGCTCCTTCGTGATGGCAAGGACACTCTCATCATCTCGTCGGGCCTGATGACGATGCGCGCGCTCGAGGCTGCCAAA
CAGCTTCGAAACGACGGAGTCGACGCTGCCGTCCTGCACGTCCCGACCATAAAGCCGCTCGATGAGGCGACGATCGTCGC
CGAGTGCCGCAAAGGTGGGCGGCTGGTGGTCGTGGCGGAGAACCACACTCTCATTGGCGGCCTTGGAGAGGCAGTCGCCG
GCACGCTGTTGCGTGCCGGCGTCGCACCGCCGGCCTTCCGCCAGATCGGCCTACCCGACCAGTTCCTGGAGGCGGGCGCC
TTGCCAACGCTCCATGACCAATACGGGCTATCGACCGTGAGGGTGACGGAGGCGGTCAAGGCCTGGCTCTCGACCTGA

Upstream 100 bases:

>100_bases
GGGTGCCATTCCTCGAGGCGCGCGATCGAAACCACTTCCTGCGCGTCGAACCCCACGAATGGGCCGAGGCCCTCAGGATC
ATCGATGCGGGAGTGGAGGC

Downstream 100 bases:

>100_bases
CGGACATCGGCCGGTTGAGGAGATGCCGGCCGTTTAAACAAGCTTGTGATGGAGGATGAAATGAGCTTGCAGATCAATCG
AAGATCTTTCCTGGCGACCG

Product: putative transketolase, C-terminal subunit

Products: D-ribose 5-phosphate; D-xylulose 5-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MRRSKYIRPAHLESGIDKPRLTTSAMIASIAGPDQPTRPAPFGNALAALARNDERIVGMSADLAKYTDLHVFRAAHPDRF
YQMGMAEQLLMMSAAGMAREGFQPWVTTYAVFASRRAYDFICLAIAEEMLDVKIVCALPGLTTGYGPSHQATEDLAMFRG
MPNLTIVDPCDASEIEQAVPAIAAHKGPVYMRLLRGNVPLVLEEYGYKFELGKAKLLRDGKDTLIISSGLMTMRALEAAK
QLRNDGVDAAVLHVPTIKPLDEATIVAECRKGGRLVVVAENHTLIGGLGEAVAGTLLRAGVAPPAFRQIGLPDQFLEAGA
LPTLHDQYGLSTVRVTEAVKAWLST

Sequences:

>Translated_345_residues
MRRSKYIRPAHLESGIDKPRLTTSAMIASIAGPDQPTRPAPFGNALAALARNDERIVGMSADLAKYTDLHVFRAAHPDRF
YQMGMAEQLLMMSAAGMAREGFQPWVTTYAVFASRRAYDFICLAIAEEMLDVKIVCALPGLTTGYGPSHQATEDLAMFRG
MPNLTIVDPCDASEIEQAVPAIAAHKGPVYMRLLRGNVPLVLEEYGYKFELGKAKLLRDGKDTLIISSGLMTMRALEAAK
QLRNDGVDAAVLHVPTIKPLDEATIVAECRKGGRLVVVAENHTLIGGLGEAVAGTLLRAGVAPPAFRQIGLPDQFLEAGA
LPTLHDQYGLSTVRVTEAVKAWLST
>Mature_345_residues
MRRSKYIRPAHLESGIDKPRLTTSAMIASIAGPDQPTRPAPFGNALAALARNDERIVGMSADLAKYTDLHVFRAAHPDRF
YQMGMAEQLLMMSAAGMAREGFQPWVTTYAVFASRRAYDFICLAIAEEMLDVKIVCALPGLTTGYGPSHQATEDLAMFRG
MPNLTIVDPCDASEIEQAVPAIAAHKGPVYMRLLRGNVPLVLEEYGYKFELGKAKLLRDGKDTLIISSGLMTMRALEAAK
QLRNDGVDAAVLHVPTIKPLDEATIVAECRKGGRLVVVAENHTLIGGLGEAVAGTLLRAGVAPPAFRQIGLPDQFLEAGA
LPTLHDQYGLSTVRVTEAVKAWLST

Specific function: Catalyzes The Acyloin Condensation Reaction Between C Atoms 2 And 3 Of Pyruvate And Glyceraldehyde 3-Phosphate To Yield 1-Deoxy-D-Xylulose-5-Phosphate (Dxp). [C]

COG id: COG3958

COG function: function code G; Transketolase, C-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI133778974, Length=310, Percent_Identity=32.5806451612903, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI205277463, Length=287, Percent_Identity=33.7979094076655, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI4507521, Length=287, Percent_Identity=33.7979094076655, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI225637459, Length=307, Percent_Identity=33.5504885993485, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI225637461, Length=307, Percent_Identity=33.5504885993485, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI225637463, Length=307, Percent_Identity=33.5504885993485, Blast_Score=133, Evalue=3e-31,
Organism=Escherichia coli, GI1786622, Length=310, Percent_Identity=29.6774193548387, Blast_Score=125, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17539652, Length=314, Percent_Identity=34.7133757961783, Blast_Score=141, Evalue=5e-34,
Organism=Drosophila melanogaster, GI45551847, Length=306, Percent_Identity=33.3333333333333, Blast_Score=131, Evalue=6e-31,
Organism=Drosophila melanogaster, GI45550715, Length=306, Percent_Identity=33.3333333333333, Blast_Score=131, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24645119, Length=332, Percent_Identity=32.8313253012048, Blast_Score=131, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24666278, Length=262, Percent_Identity=35.1145038167939, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21358145, Length=305, Percent_Identity=26.2295081967213, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24650940, Length=305, Percent_Identity=26.2295081967213, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: 2.2.1.1

Molecular weight: Translated: 37297; Mature: 37297

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSKYIRPAHLESGIDKPRLTTSAMIASIAGPDQPTRPAPFGNALAALARNDERIVGMS
CCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEECC
ADLAKYTDLHVFRAAHPDRFYQMGMAEQLLMMSAAGMAREGFQPWVTTYAVFASRRAYDF
CHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHH
ICLAIAEEMLDVKIVCALPGLTTGYGPSHQATEDLAMFRGMPNLTIVDPCDASEIEQAVP
HHHHHHHHHHCEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCEEECCCCHHHHHHHHH
AIAAHKGPVYMRLLRGNVPLVLEEYGYKFELGKAKLLRDGKDTLIISSGLMTMRALEAAK
HHHHCCCCEEEEEECCCCCEEECCCCCEEEECCHHHHCCCCCEEEEECCHHHHHHHHHHH
QLRNDGVDAAVLHVPTIKPLDEATIVAECRKGGRLVVVAENHTLIGGLGEAVAGTLLRAG
HHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCEEEEEECCCEEECCHHHHHHHHHHHHC
VAPPAFRQIGLPDQFLEAGALPTLHDQYGLSTVRVTEAVKAWLST
CCCHHHHHCCCCHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRRSKYIRPAHLESGIDKPRLTTSAMIASIAGPDQPTRPAPFGNALAALARNDERIVGMS
CCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEECC
ADLAKYTDLHVFRAAHPDRFYQMGMAEQLLMMSAAGMAREGFQPWVTTYAVFASRRAYDF
CHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHH
ICLAIAEEMLDVKIVCALPGLTTGYGPSHQATEDLAMFRGMPNLTIVDPCDASEIEQAVP
HHHHHHHHHHCEEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCEEECCCCHHHHHHHHH
AIAAHKGPVYMRLLRGNVPLVLEEYGYKFELGKAKLLRDGKDTLIISSGLMTMRALEAAK
HHHHCCCCEEEEEECCCCCEEECCCCCEEEECCHHHHCCCCCEEEEECCHHHHHHHHHHH
QLRNDGVDAAVLHVPTIKPLDEATIVAECRKGGRLVVVAENHTLIGGLGEAVAGTLLRAG
HHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCEEEEEECCCEEECCHHHHHHHHHHHHC
VAPPAFRQIGLPDQFLEAGALPTLHDQYGLSTVRVTEAVKAWLST
CCCHHHHHCCCCHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: sedoheptulose 7-phosphate; D-glyceraldehyde 3-phosphate

Specific reaction: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]