Click here to switch to the map view.

The map label for this gene is resE [H]

Identifier: 190894857

GI number: 190894857

Start: 568307

End: 570649

Strand: Reverse

Name: resE [H]

Synonym: RHECIAT_PC0000522

Alternate gene names: 190894857

Gene position: 570649-568307 (Counterclockwise)

Preceding gene: 190894859

Following gene: 190894856

Centisome position: 52.28

GC content: 61.42

Gene sequence:

>2343_bases
ATGGATGGTGCATTGACGGGCCTGCCCGGAATTGGCGATTGCCTTGATCAACACGATATCGTGCTCGGCGTTCACCTCGA
TCGAGATGAATTTCATGAATGCGCCGCTAAGCGGCCGTTGCCGGAGCTTATTCTGCTCGACGCCCTGTCGCCGGAGGGGC
GCGGTCTTGAAGACTGCCGGCGTCTCAAGGGAAACGCCGTAACGCGTGATATCCCGGTGATTATTGTGGTCTCGCCTCAG
GACGAGCAAACCAGGATTGCGGGGTTTGCCGCCGGTGCGGTGGATTGTGTCTCCAACCTCGTCTCCGCCGCCGAGCTCGT
TGCCCGCATCAAGCGACACATCGAACTCGGCGCGGCGCAGGCGCACCTGCGGCGGCGCAACGAGCAACTCGACACGGCGC
TTGCCAGCATGGGACAGGGTGTCTGCCTGTTTGACGAGGACGGCCGGCTGCTTCTTTCGAATAATCGGTATGCGGAGGTT
TACGGACTCGATCCCGCCGTCATTCATCCGGGGCAGTCACTGGAAGACATCCTGAAACTGCGAGAGGACGTTGGCGCCGT
CCCCGCCACGTCCACGTCGGACTATCTCGCCTGGGCCGTAGCGACCAATATGGGCGACGCGCCCCAGGATTGGATCAAGG
AACTCAAAACCGGCCAGATCATCCGCGGCTATCATCAGCGAACGCCGGAGGGCGGCTGGGTATCGACCCATGAGGATATC
ACACAGGCCTGGTTTGCGGAAAAAGCGCTTGCAGAGGCGCACGCCCAGGCAGAACGCGCCGAGCAGGAGGCGCGGGCGGC
ACATGCCCGGCTTCTGGCCGCTTTCGAAGTCGTCCCCGAAGGCCTCGTTCTGTTCGACGCCGAAGACCGCTTCGTCCTGT
GGAACCGGCGATACGAACAGCTTTACGCAGAAAGCGGCGATATGCTTGTCAAAGGGATGCGCTTCGAAGACCGCTTGCGC
ACAGGTCTCGAATGCGGCCAGTATCCGGAGGCGGTCGGGCGCGAACAGGAATGGCTTGAGGAGCGTCTGGCCCATCATGC
CGAGCCCACCAGCAAACACGAGCAGCGCCTGCCCGGAAACCGATGGATCCGGATCGAGGAACGCCGGATCTCCGAAGGGG
GCAGCGTCGGCATCCGCGTCGATATCACCGATCTGAAGATGCAGGAGGCGTCGTTCAGGCTGCTGTTCGAAGGCAATCCG
ATGCCGATGTGGGTGTACGACCGCGAAACCCTGAAATTCCTTCATGTCAATCAGGCCGCCATCGATCACTATGGCTACCG
GCTGGAGCAGTTCCTGACAATGACGCTGCGTGACATTCAGGCGCCGCAGGACGCCGATCGGGCAACGGCTGCCGTCTTCG
ACGCCGAGGATCCAGCCGCCACGACCTGCTCCTTCCGCCACCTCAAGGCAGATGGCGGCGCCATCGAAGTCACCGTCTAT
TCCACTTGCTTGAACCACAAGGGCAAGGCGGCATCACTGATGGCCGTCGTCGACGTCACCGAGGCCAAGCGTGCCGAAAA
GGCATTGCTGCAGCACCGCGACACGCTGGAAGAGATGGTGCGCTCGCGCACCGTCGAACTGGCGCGGCAGACGGAAGAAC
TCGAGCGCATGCTCGAACAGGAAAAGCAGATCAACGAATTGCAGCGCCAGTTCGTCTCGATGGCGTCGCATGAGTTCCGC
ACCCCGCTCGCGGTGATCGACGGTGCGGCGCAGCGGCTCATTCGGCGCAAGGAGGCGGCGACGCCGGAATTCCTTGCCGA
AAAGGCCGACCAGATCCGCAGCTCGGTTTCCCGTATGCTTGAACTGATGGAAAGCATTCTTGCTGCCGGGCGGTTGGATC
ATGGCCGGATCACCATCGTGCCGAAGCCCTGCTCGATCGCCGAAATCATCGAAACCTGCAGCGCCCGTCAGGAAAGCATC
CGGCGGTCGCATCGCTTTCTGCTTAAATTGGACGAGCTTCCCGAAACCATCTACGGCGATCGTCCCGCGCTCGACCAAGT
CTTCAGCAACCTCTTCTCCAATGCCGTGAAATACGCGCCGGATTCTCCAAACGTCCATGTTTCAGGATGGCAGGAAGGAG
AACGCGTCTGCATCACCGTGCGCGACGAAGGCATTGGCATCGACGCCGACGACCTCCCGAAGATGTTCCAGCGTTATTTC
CGCGCCAGAAGCTCCACGGGCATTGCCGGCACCGGCATCGGCCTCAATCTCGTCAAGCAGATTGTCGAGCTTCACGGGGG
AACGATAGACGTGGCGAGCAGCCGCGGAAACGGCACGACATTTACGCTGCGGATTCCGATAGGCGCCGAAATGTTGGACG
AGCAGCGCGTTGCGACGGGCTAG

Upstream 100 bases:

>100_bases
CCAGCGGTAAGTCGCTTATTAACTCATACGACTTATGGTCGCGTCGACTTGCGTGAACGGGGGAGTAGTCTTGTCCGACG
AGCTGCACATGATCTCCGCA

Downstream 100 bases:

>100_bases
GCAAGCGGGTGCGGCGCATATTGGGCGAATTTCAGTAGCGCCCCGTAGAAGGGTTCAGAGGATTGACGATAATTTTTCTC
CTTCGGCACGGAGAGACGAT

Product: putative two-component sensor histidine kinase/response regulator hybrid protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 780; Mature: 780

Protein sequence:

>780_residues
MDGALTGLPGIGDCLDQHDIVLGVHLDRDEFHECAAKRPLPELILLDALSPEGRGLEDCRRLKGNAVTRDIPVIIVVSPQ
DEQTRIAGFAAGAVDCVSNLVSAAELVARIKRHIELGAAQAHLRRRNEQLDTALASMGQGVCLFDEDGRLLLSNNRYAEV
YGLDPAVIHPGQSLEDILKLREDVGAVPATSTSDYLAWAVATNMGDAPQDWIKELKTGQIIRGYHQRTPEGGWVSTHEDI
TQAWFAEKALAEAHAQAERAEQEARAAHARLLAAFEVVPEGLVLFDAEDRFVLWNRRYEQLYAESGDMLVKGMRFEDRLR
TGLECGQYPEAVGREQEWLEERLAHHAEPTSKHEQRLPGNRWIRIEERRISEGGSVGIRVDITDLKMQEASFRLLFEGNP
MPMWVYDRETLKFLHVNQAAIDHYGYRLEQFLTMTLRDIQAPQDADRATAAVFDAEDPAATTCSFRHLKADGGAIEVTVY
STCLNHKGKAASLMAVVDVTEAKRAEKALLQHRDTLEEMVRSRTVELARQTEELERMLEQEKQINELQRQFVSMASHEFR
TPLAVIDGAAQRLIRRKEAATPEFLAEKADQIRSSVSRMLELMESILAAGRLDHGRITIVPKPCSIAEIIETCSARQESI
RRSHRFLLKLDELPETIYGDRPALDQVFSNLFSNAVKYAPDSPNVHVSGWQEGERVCITVRDEGIGIDADDLPKMFQRYF
RARSSTGIAGTGIGLNLVKQIVELHGGTIDVASSRGNGTTFTLRIPIGAEMLDEQRVATG

Sequences:

>Translated_780_residues
MDGALTGLPGIGDCLDQHDIVLGVHLDRDEFHECAAKRPLPELILLDALSPEGRGLEDCRRLKGNAVTRDIPVIIVVSPQ
DEQTRIAGFAAGAVDCVSNLVSAAELVARIKRHIELGAAQAHLRRRNEQLDTALASMGQGVCLFDEDGRLLLSNNRYAEV
YGLDPAVIHPGQSLEDILKLREDVGAVPATSTSDYLAWAVATNMGDAPQDWIKELKTGQIIRGYHQRTPEGGWVSTHEDI
TQAWFAEKALAEAHAQAERAEQEARAAHARLLAAFEVVPEGLVLFDAEDRFVLWNRRYEQLYAESGDMLVKGMRFEDRLR
TGLECGQYPEAVGREQEWLEERLAHHAEPTSKHEQRLPGNRWIRIEERRISEGGSVGIRVDITDLKMQEASFRLLFEGNP
MPMWVYDRETLKFLHVNQAAIDHYGYRLEQFLTMTLRDIQAPQDADRATAAVFDAEDPAATTCSFRHLKADGGAIEVTVY
STCLNHKGKAASLMAVVDVTEAKRAEKALLQHRDTLEEMVRSRTVELARQTEELERMLEQEKQINELQRQFVSMASHEFR
TPLAVIDGAAQRLIRRKEAATPEFLAEKADQIRSSVSRMLELMESILAAGRLDHGRITIVPKPCSIAEIIETCSARQESI
RRSHRFLLKLDELPETIYGDRPALDQVFSNLFSNAVKYAPDSPNVHVSGWQEGERVCITVRDEGIGIDADDLPKMFQRYF
RARSSTGIAGTGIGLNLVKQIVELHGGTIDVASSRGNGTTFTLRIPIGAEMLDEQRVATG
>Mature_780_residues
MDGALTGLPGIGDCLDQHDIVLGVHLDRDEFHECAAKRPLPELILLDALSPEGRGLEDCRRLKGNAVTRDIPVIIVVSPQ
DEQTRIAGFAAGAVDCVSNLVSAAELVARIKRHIELGAAQAHLRRRNEQLDTALASMGQGVCLFDEDGRLLLSNNRYAEV
YGLDPAVIHPGQSLEDILKLREDVGAVPATSTSDYLAWAVATNMGDAPQDWIKELKTGQIIRGYHQRTPEGGWVSTHEDI
TQAWFAEKALAEAHAQAERAEQEARAAHARLLAAFEVVPEGLVLFDAEDRFVLWNRRYEQLYAESGDMLVKGMRFEDRLR
TGLECGQYPEAVGREQEWLEERLAHHAEPTSKHEQRLPGNRWIRIEERRISEGGSVGIRVDITDLKMQEASFRLLFEGNP
MPMWVYDRETLKFLHVNQAAIDHYGYRLEQFLTMTLRDIQAPQDADRATAAVFDAEDPAATTCSFRHLKADGGAIEVTVY
STCLNHKGKAASLMAVVDVTEAKRAEKALLQHRDTLEEMVRSRTVELARQTEELERMLEQEKQINELQRQFVSMASHEFR
TPLAVIDGAAQRLIRRKEAATPEFLAEKADQIRSSVSRMLELMESILAAGRLDHGRITIVPKPCSIAEIIETCSARQESI
RRSHRFLLKLDELPETIYGDRPALDQVFSNLFSNAVKYAPDSPNVHVSGWQEGERVCITVRDEGIGIDADDLPKMFQRYF
RARSSTGIAGTGIGLNLVKQIVELHGGTIDVASSRGNGTTFTLRIPIGAEMLDEQRVATG

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=35.5555555555556, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788393, Length=246, Percent_Identity=29.6747967479675, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI145693157, Length=245, Percent_Identity=28.1632653061224, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI48994928, Length=233, Percent_Identity=31.7596566523605, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI87081816, Length=269, Percent_Identity=28.6245353159851, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI1786912, Length=237, Percent_Identity=28.2700421940928, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1790861, Length=250, Percent_Identity=26.8, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1788549, Length=246, Percent_Identity=28.8617886178862, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1786600, Length=243, Percent_Identity=25.5144032921811, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1788279, Length=202, Percent_Identity=28.2178217821782, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789149, Length=263, Percent_Identity=25.0950570342205, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788713, Length=262, Percent_Identity=27.0992366412214, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1786783, Length=250, Percent_Identity=26.8, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1790551, Length=238, Percent_Identity=27.3109243697479, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=242, Percent_Identity=24.7933884297521, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1786599, Length=73, Percent_Identity=43.8356164383562, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI87082128, Length=221, Percent_Identity=24.8868778280543, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 87008; Mature: 87008

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGALTGLPGIGDCLDQHDIVLGVHLDRDEFHECAAKRPLPELILLDALSPEGRGLEDCR
CCCCCCCCCCCHHHCCCCCEEEEEEECHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHH
RLKGNAVTRDIPVIIVVSPQDEQTRIAGFAAGAVDCVSNLVSAAELVARIKRHIELGAAQ
HHCCCCEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHLRRRNEQLDTALASMGQGVCLFDEDGRLLLSNNRYAEVYGLDPAVIHPGQSLEDILKL
HHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCEEEEECCCCCEECCCCCHHHHHHH
REDVGAVPATSTSDYLAWAVATNMGDAPQDWIKELKTGQIIRGYHQRTPEGGWVSTHEDI
HHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHH
TQAWFAEKALAEAHAQAERAEQEARAAHARLLAAFEVVPEGLVLFDAEDRFVLWNRRYEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECHHHHH
LYAESGDMLVKGMRFEDRLRTGLECGQYPEAVGREQEWLEERLAHHAEPTSKHEQRLPGN
HHHCCCCCEEECCCHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHCCCCCCHHHHCCCCC
RWIRIEERRISEGGSVGIRVDITDLKMQEASFRLLFEGNPMPMWVYDRETLKFLHVNQAA
CEEEEEHHHCCCCCCEEEEEEEECCEECCCCEEEEECCCCCEEEEECHHHHHEEECCHHH
IDHYGYRLEQFLTMTLRDIQAPQDADRATAAVFDAEDPAATTCSFRHLKADGGAIEVTVY
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEECCCCCCCCCEEEEEEECCCCEEEEEEE
STCLNHKGKAASLMAVVDVTEAKRAEKALLQHRDTLEEMVRSRTVELARQTEELERMLEQ
EHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKQINELQRQFVSMASHEFRTPLAVIDGAAQRLIRRKEAATPEFLAEKADQIRSSVSRML
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ELMESILAAGRLDHGRITIVPKPCSIAEIIETCSARQESIRRSHRFLLKLDELPETIYGD
HHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
RPALDQVFSNLFSNAVKYAPDSPNVHVSGWQEGERVCITVRDEGIGIDADDLPKMFQRYF
CCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHH
RARSSTGIAGTGIGLNLVKQIVELHGGTIDVASSRGNGTTFTLRIPIGAEMLDEQRVATG
HHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCHHHHHHHHCCCC
>Mature Secondary Structure
MDGALTGLPGIGDCLDQHDIVLGVHLDRDEFHECAAKRPLPELILLDALSPEGRGLEDCR
CCCCCCCCCCCHHHCCCCCEEEEEEECHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHH
RLKGNAVTRDIPVIIVVSPQDEQTRIAGFAAGAVDCVSNLVSAAELVARIKRHIELGAAQ
HHCCCCEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHLRRRNEQLDTALASMGQGVCLFDEDGRLLLSNNRYAEVYGLDPAVIHPGQSLEDILKL
HHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCEEEEECCCCCEECCCCCHHHHHHH
REDVGAVPATSTSDYLAWAVATNMGDAPQDWIKELKTGQIIRGYHQRTPEGGWVSTHEDI
HHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHH
TQAWFAEKALAEAHAQAERAEQEARAAHARLLAAFEVVPEGLVLFDAEDRFVLWNRRYEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECHHHHH
LYAESGDMLVKGMRFEDRLRTGLECGQYPEAVGREQEWLEERLAHHAEPTSKHEQRLPGN
HHHCCCCCEEECCCHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHCCCCCCHHHHCCCCC
RWIRIEERRISEGGSVGIRVDITDLKMQEASFRLLFEGNPMPMWVYDRETLKFLHVNQAA
CEEEEEHHHCCCCCCEEEEEEEECCEECCCCEEEEECCCCCEEEEECHHHHHEEECCHHH
IDHYGYRLEQFLTMTLRDIQAPQDADRATAAVFDAEDPAATTCSFRHLKADGGAIEVTVY
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEECCCCCCCCCEEEEEEECCCCEEEEEEE
STCLNHKGKAASLMAVVDVTEAKRAEKALLQHRDTLEEMVRSRTVELARQTEELERMLEQ
EHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKQINELQRQFVSMASHEFRTPLAVIDGAAQRLIRRKEAATPEFLAEKADQIRSSVSRML
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ELMESILAAGRLDHGRITIVPKPCSIAEIIETCSARQESIRRSHRFLLKLDELPETIYGD
HHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
RPALDQVFSNLFSNAVKYAPDSPNVHVSGWQEGERVCITVRDEGIGIDADDLPKMFQRYF
CCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHH
RARSSTGIAGTGIGLNLVKQIVELHGGTIDVASSRGNGTTFTLRIPIGAEMLDEQRVATG
HHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]