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The map label for this gene is mcpBc [H]

Identifier: 190894832

GI number: 190894832

Start: 540717

End: 542861

Strand: Reverse

Name: mcpBc [H]

Synonym: RHECIAT_PC0000497

Alternate gene names: 190894832

Gene position: 542861-540717 (Counterclockwise)

Preceding gene: 190894833

Following gene: 190894828

Centisome position: 49.73

GC content: 64.99

Gene sequence:

>2145_bases
ATGTTGCATTTCTGGAATAAATTCGGCATTCGCGCGCAGATCACCGCAGGTTTCGTGCCATTGATCCTGCTGATGAGCCT
GCTGACCGTCAGCGCGATCTCGGGCATGAACGGGCTCGCCGCCATCTTCGCTTCCTATCGCGCCACGGCCGGCCAGAGCC
TCGCCATCTCGGATTACAGCGAGCAGTTGCACGAGGTCCAGATGTCGGCCGAAGCCTTCCGCTCCACGCCGACGCAGGCT
GTCGTCGACAGTTTCCGCGCCGGCGTGAAGGCCTTCGAGGCCGACGATCCGCGGTTTGCCGGCAACAAGGACCTGCAGTC
GGGCCTGGCGACGATCCGCCAGGATATTGCCGCCTATGGCAAGGCCTTCGAACAGATCGTCGCCCTTCAGGCCCGCCGCG
ACCTGCTGATCTCCAAGGTTACCGAATTCGGGCCCTGGACCAGCATCGCGCTCAACGATGTCATGCGCAGTGCCTGGCGC
CAGAACGACGTCGCCCAGCTGCATATGACGGCGGCGACGCTGGAGGCCCTGAACCGCAGCCTCTATTTCTCTGAACGCTT
CGTGCATTCTGAGGATTTTGCCGCCTATGATACGGCCCAGGCGGCGCTTGCCGAAGCGGTGACACTCAATGAGACTGCCG
CCAAGGCGGCGAAGGACGAGCTGCAGAAGAAGCGCCTGATGGGCGCCGGCCAGCTCATGCAGAACTATACCGCCCGTCTC
GGCGACATGAAGGAGGTGCTGCAGGCTTCCGGCAATATCCGTCAGACGCAGCTCGGTGTGCTCGCGCCGAAAATATCGGC
CGAGTTCAAGGATTTGCAGGCGACGGTGACCGGCGCCCAGACGAATCTCGACGGCTCGGTCGAAACCATGGTTTCCTCCG
CGACCAGCACGACGCTGGTCATCAGCGGCCTCCTGATCGTCATCGGCCTCGTGCTCTCCTATTTCGTCGGCCGGCTGATT
TCCTCGGCGGTGCGCGGGATGGCGCAGTCCATGGAACAGCTTGCTCGCGGCGAGGAAGGGATTTCGATCACCGGCGTCGA
GCACCGCCACGAACTCGGCGCCATGGCGCGTTCGCTGAAGGTTTTCCAGGAGACCGGCCGCGCCAAGCTGATCGCCGAGG
CCAATGCCGAACGTGCGCGTCTCGCCGCCGAAGAAGAGCGGCTGCGCCAGGAAGCCGAGCGGCTTGCCGACGCGCAGGTC
ATGGAACATGCCTTCCGGCAGATCTCGCTCGGTCTCGATGCGCTCTCGAAGGGCGACCTCTCCGTGCGCGTCGGTGAAGT
CGACCATCGCCATGTCAGGATCCGCGATCACTTCAACAGCTCGGTCGCAAGCCTCGAAGAAGCGATCGACTCCGTCATCC
GCGCGGTCACGACCATCCGCTCCGGCCTTGCGGAAATCTCCACCGCCTCCAACGATCTCGCCCGCCGCACCGAGCAGCAG
GCGGCTTCGCTGGAGGAAACCGTCGCGGCGCTGGGCGATGTCACCCGCGGCGTCAACGGAACGGCGGAGGGCGCCAGCCG
CGCCCAGGCTGTGGTGGCCACGGCCCGCACCAATGCCGAAAAGGGCGGCGAGATCGTCTCGCGCGCCATCGCCGCGATGA
CGGAAATCCAGAACTCCTCGTCCAAGATTGGTAACATCATCAGCGTCATCGACGAGATCGCTTTCCAGACCAACCTGCTG
GCGCTGAACGCTGGTGTCGAGGCGGCGCGTGCCGGCGAGGCCGGCAAGGGTTTTGCCGTCGTCGCCCAGGAAGTCCGCGA
ACTCGCCCAGCGTTCCGCCAATGCGGCACGGGAGATCAAGGAACTGATCTCCACCTCCTCGGCACAGGTCAAGACCGGCG
TCGAGCTGGTGGGTGAATCCGGCCTCTCGCTCGAACAGATCGTCGAGCAGGTCACGGCCATGAACGCGACCGTCGCCGAG
ATCGCCATCGCCGCCCGCGAGCAGGCGACCAGCCTGCGCGAGGTCTCGGCCGCCGGCGACCAGATGGACAAGGTCACGCA
GCAGAACGCCGCGATGGTCGAGGAAACCACGGCCGCCGCCCAGAGCCTGACCCAGGAAACCGAAAGCCTCGCCGAGCTGC
TGCGGCGCTTCAAGACCGGCAGCGGCCGGGGGTCGGAACACCGCCATTACGCGATGGCGTCGTAA

Upstream 100 bases:

>100_bases
GAGAAGGTGCCCCGCGAAAACAACGTTCCCTTCGAACTCGTCACCCCTGAGAACATTGCCCAATACCTGCCGAAGAGCCA
GTGAGCATAAGAGGCCTATG

Downstream 100 bases:

>100_bases
CGTTCTGCTAACGCAGCAAAGAGAATGCCGCCGCCTTCAAAGGGCGGCGGTCGCGTCAATGGCCTCCGGCCGCCGGACTG
TGCGGCGCGCCGGCGATGCT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 714; Mature: 714

Protein sequence:

>714_residues
MLHFWNKFGIRAQITAGFVPLILLMSLLTVSAISGMNGLAAIFASYRATAGQSLAISDYSEQLHEVQMSAEAFRSTPTQA
VVDSFRAGVKAFEADDPRFAGNKDLQSGLATIRQDIAAYGKAFEQIVALQARRDLLISKVTEFGPWTSIALNDVMRSAWR
QNDVAQLHMTAATLEALNRSLYFSERFVHSEDFAAYDTAQAALAEAVTLNETAAKAAKDELQKKRLMGAGQLMQNYTARL
GDMKEVLQASGNIRQTQLGVLAPKISAEFKDLQATVTGAQTNLDGSVETMVSSATSTTLVISGLLIVIGLVLSYFVGRLI
SSAVRGMAQSMEQLARGEEGISITGVEHRHELGAMARSLKVFQETGRAKLIAEANAERARLAAEEERLRQEAERLADAQV
MEHAFRQISLGLDALSKGDLSVRVGEVDHRHVRIRDHFNSSVASLEEAIDSVIRAVTTIRSGLAEISTASNDLARRTEQQ
AASLEETVAALGDVTRGVNGTAEGASRAQAVVATARTNAEKGGEIVSRAIAAMTEIQNSSSKIGNIISVIDEIAFQTNLL
ALNAGVEAARAGEAGKGFAVVAQEVRELAQRSANAAREIKELISTSSAQVKTGVELVGESGLSLEQIVEQVTAMNATVAE
IAIAAREQATSLREVSAAGDQMDKVTQQNAAMVEETTAAAQSLTQETESLAELLRRFKTGSGRGSEHRHYAMAS

Sequences:

>Translated_714_residues
MLHFWNKFGIRAQITAGFVPLILLMSLLTVSAISGMNGLAAIFASYRATAGQSLAISDYSEQLHEVQMSAEAFRSTPTQA
VVDSFRAGVKAFEADDPRFAGNKDLQSGLATIRQDIAAYGKAFEQIVALQARRDLLISKVTEFGPWTSIALNDVMRSAWR
QNDVAQLHMTAATLEALNRSLYFSERFVHSEDFAAYDTAQAALAEAVTLNETAAKAAKDELQKKRLMGAGQLMQNYTARL
GDMKEVLQASGNIRQTQLGVLAPKISAEFKDLQATVTGAQTNLDGSVETMVSSATSTTLVISGLLIVIGLVLSYFVGRLI
SSAVRGMAQSMEQLARGEEGISITGVEHRHELGAMARSLKVFQETGRAKLIAEANAERARLAAEEERLRQEAERLADAQV
MEHAFRQISLGLDALSKGDLSVRVGEVDHRHVRIRDHFNSSVASLEEAIDSVIRAVTTIRSGLAEISTASNDLARRTEQQ
AASLEETVAALGDVTRGVNGTAEGASRAQAVVATARTNAEKGGEIVSRAIAAMTEIQNSSSKIGNIISVIDEIAFQTNLL
ALNAGVEAARAGEAGKGFAVVAQEVRELAQRSANAAREIKELISTSSAQVKTGVELVGESGLSLEQIVEQVTAMNATVAE
IAIAAREQATSLREVSAAGDQMDKVTQQNAAMVEETTAAAQSLTQETESLAELLRRFKTGSGRGSEHRHYAMAS
>Mature_714_residues
MLHFWNKFGIRAQITAGFVPLILLMSLLTVSAISGMNGLAAIFASYRATAGQSLAISDYSEQLHEVQMSAEAFRSTPTQA
VVDSFRAGVKAFEADDPRFAGNKDLQSGLATIRQDIAAYGKAFEQIVALQARRDLLISKVTEFGPWTSIALNDVMRSAWR
QNDVAQLHMTAATLEALNRSLYFSERFVHSEDFAAYDTAQAALAEAVTLNETAAKAAKDELQKKRLMGAGQLMQNYTARL
GDMKEVLQASGNIRQTQLGVLAPKISAEFKDLQATVTGAQTNLDGSVETMVSSATSTTLVISGLLIVIGLVLSYFVGRLI
SSAVRGMAQSMEQLARGEEGISITGVEHRHELGAMARSLKVFQETGRAKLIAEANAERARLAAEEERLRQEAERLADAQV
MEHAFRQISLGLDALSKGDLSVRVGEVDHRHVRIRDHFNSSVASLEEAIDSVIRAVTTIRSGLAEISTASNDLARRTEQQ
AASLEETVAALGDVTRGVNGTAEGASRAQAVVATARTNAEKGGEIVSRAIAAMTEIQNSSSKIGNIISVIDEIAFQTNLL
ALNAGVEAARAGEAGKGFAVVAQEVRELAQRSANAAREIKELISTSSAQVKTGVELVGESGLSLEQIVEQVTAMNATVAE
IAIAAREQATSLREVSAAGDQMDKVTQQNAAMVEETTAAAQSLTQETESLAELLRRFKTGSGRGSEHRHYAMAS

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=293, Percent_Identity=44.0273037542662, Blast_Score=196, Evalue=4e-51,
Organism=Escherichia coli, GI2367378, Length=211, Percent_Identity=53.5545023696682, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1788195, Length=230, Percent_Identity=48.695652173913, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1787690, Length=310, Percent_Identity=40.6451612903226, Blast_Score=190, Evalue=3e-49,
Organism=Escherichia coli, GI1789453, Length=228, Percent_Identity=42.1052631578947, Blast_Score=169, Evalue=5e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 76413; Mature: 76413

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHFWNKFGIRAQITAGFVPLILLMSLLTVSAISGMNGLAAIFASYRATAGQSLAISDYS
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEHHHHH
EQLHEVQMSAEAFRSTPTQAVVDSFRAGVKAFEADDPRFAGNKDLQSGLATIRQDIAAYG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KAFEQIVALQARRDLLISKVTEFGPWTSIALNDVMRSAWRQNDVAQLHMTAATLEALNRS
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LYFSERFVHSEDFAAYDTAQAALAEAVTLNETAAKAAKDELQKKRLMGAGQLMQNYTARL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GDMKEVLQASGNIRQTQLGVLAPKISAEFKDLQATVTGAQTNLDGSVETMVSSATSTTLV
HHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
ISGLLIVIGLVLSYFVGRLISSAVRGMAQSMEQLARGEEGISITGVEHRHELGAMARSLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHH
VFQETGRAKLIAEANAERARLAAEEERLRQEAERLADAQVMEHAFRQISLGLDALSKGDL
HHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SVRVGEVDHRHVRIRDHFNSSVASLEEAIDSVIRAVTTIRSGLAEISTASNDLARRTEQQ
EEEECCCCCCEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AASLEETVAALGDVTRGVNGTAEGASRAQAVVATARTNAEKGGEIVSRAIAAMTEIQNSS
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCH
SKIGNIISVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSANAAREIK
HHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ELISTSSAQVKTGVELVGESGLSLEQIVEQVTAMNATVAEIAIAAREQATSLREVSAAGD
HHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QMDKVTQQNAAMVEETTAAAQSLTQETESLAELLRRFKTGSGRGSEHRHYAMAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLHFWNKFGIRAQITAGFVPLILLMSLLTVSAISGMNGLAAIFASYRATAGQSLAISDYS
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEHHHHH
EQLHEVQMSAEAFRSTPTQAVVDSFRAGVKAFEADDPRFAGNKDLQSGLATIRQDIAAYG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KAFEQIVALQARRDLLISKVTEFGPWTSIALNDVMRSAWRQNDVAQLHMTAATLEALNRS
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LYFSERFVHSEDFAAYDTAQAALAEAVTLNETAAKAAKDELQKKRLMGAGQLMQNYTARL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GDMKEVLQASGNIRQTQLGVLAPKISAEFKDLQATVTGAQTNLDGSVETMVSSATSTTLV
HHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
ISGLLIVIGLVLSYFVGRLISSAVRGMAQSMEQLARGEEGISITGVEHRHELGAMARSLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHH
VFQETGRAKLIAEANAERARLAAEEERLRQEAERLADAQVMEHAFRQISLGLDALSKGDL
HHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SVRVGEVDHRHVRIRDHFNSSVASLEEAIDSVIRAVTTIRSGLAEISTASNDLARRTEQQ
EEEECCCCCCEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AASLEETVAALGDVTRGVNGTAEGASRAQAVVATARTNAEKGGEIVSRAIAAMTEIQNSS
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCH
SKIGNIISVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSANAAREIK
HHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ELISTSSAQVKTGVELVGESGLSLEQIVEQVTAMNATVAEIAIAAREQATSLREVSAAGD
HHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QMDKVTQQNAAMVEETTAAAQSLTQETESLAELLRRFKTGSGRGSEHRHYAMAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]