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The map label for this gene is glpR [H]

Identifier: 190894670

GI number: 190894670

Start: 359348

End: 360121

Strand: Reverse

Name: glpR [H]

Synonym: RHECIAT_PC0000333

Alternate gene names: 190894670

Gene position: 360121-359348 (Counterclockwise)

Preceding gene: 190894671

Following gene: 190894669

Centisome position: 32.99

GC content: 59.56

Gene sequence:

>774_bases
ATGTTCTTGACCGACCGACAGACTGAAATCGTGGCGATCGCGAAATCGAGTGGCAGGGTTCTGGTCGAGGAGCTCGCCTC
ACGCTTTTCGGTGACGCCGCAAACCATCCGCAAGGACCTCAACGATCTCTGCGATGCCCAGGTGCTGACGCGCATCCATG
GCGGCGCCACATTCCCGAGCGGCACCGAGAACGTCAAATACGAGGCGCGCCGCCAGATTGCCGCTTCGGAGAAACAGGCG
ATTGGCATGGCGGCCGTCGAACTGATCCCGAGCGGGGCCTCGCTCTTCATCAATATCGGCACGACGACCGAGGCGGTGGG
CGAAGCGCTCGCCAATCATCACGAGCTGATGGTGATCACCAATAATATCAACGTCGCCAATCGGTTACGTCTATTTCCGG
CAATCGAGGTGGTGATCGCCGGCGGAGTCGTGCGTGGGTCGGACGGCGGTATCGTCGGCGAAGCGGCGGTCGATTTCATC
CGCCAGTTCAAGGTCGATTATGCCGTGATCGGCGCCTCGGCGATCGATATCGACGGCGCGCTTCTCGACTATGACTTTCG
CGAGGTGAAGGTCGCACAGGCGATCATCGCCAATGCCCGCCACGTTATTCTCGTTGCCGATTCCACGAAGTTCGAACGCA
CCGCGCCGGTCCGGATCGGTCAGCTCTCCCAGGTTCACACCTTCATCACCGACCACTGTCCGGTGCCGTCGATCCGCAAT
CTCTGCCTGGAAAACAATGTGAAGCTGATCGAAACAAACAGCAGATCGCGATAA

Upstream 100 bases:

>100_bases
GCCGCCATCAGTCGGGGCGCAAAAACCTGGCCGCCGGCAATTAGGCATTGCGCCGCCCTTCGCTTTCTTTAAAAACGAAA
GCAGATCGAAAGGGGCGCCG

Downstream 100 bases:

>100_bases
CGCGACAACATTCGTTTGACATTCGTATTTCTTTCGTTTTAACTGATGTCACTTTCGCAATCGCGCAAATTTTGTGCGAT
GCGAAATCAGCAGCAGGCTC

Product: putative DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MFLTDRQTEIVAIAKSSGRVLVEELASRFSVTPQTIRKDLNDLCDAQVLTRIHGGATFPSGTENVKYEARRQIAASEKQA
IGMAAVELIPSGASLFINIGTTTEAVGEALANHHELMVITNNINVANRLRLFPAIEVVIAGGVVRGSDGGIVGEAAVDFI
RQFKVDYAVIGASAIDIDGALLDYDFREVKVAQAIIANARHVILVADSTKFERTAPVRIGQLSQVHTFITDHCPVPSIRN
LCLENNVKLIETNSRSR

Sequences:

>Translated_257_residues
MFLTDRQTEIVAIAKSSGRVLVEELASRFSVTPQTIRKDLNDLCDAQVLTRIHGGATFPSGTENVKYEARRQIAASEKQA
IGMAAVELIPSGASLFINIGTTTEAVGEALANHHELMVITNNINVANRLRLFPAIEVVIAGGVVRGSDGGIVGEAAVDFI
RQFKVDYAVIGASAIDIDGALLDYDFREVKVAQAIIANARHVILVADSTKFERTAPVRIGQLSQVHTFITDHCPVPSIRN
LCLENNVKLIETNSRSR
>Mature_257_residues
MFLTDRQTEIVAIAKSSGRVLVEELASRFSVTPQTIRKDLNDLCDAQVLTRIHGGATFPSGTENVKYEARRQIAASEKQA
IGMAAVELIPSGASLFINIGTTTEAVGEALANHHELMVITNNINVANRLRLFPAIEVVIAGGVVRGSDGGIVGEAAVDFI
RQFKVDYAVIGASAIDIDGALLDYDFREVKVAQAIIANARHVILVADSTKFERTAPVRIGQLSQVHTFITDHCPVPSIRN
LCLENNVKLIETNSRSR

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=249, Percent_Identity=44.9799196787149, Blast_Score=235, Evalue=3e-63,
Organism=Escherichia coli, GI87082344, Length=245, Percent_Identity=37.1428571428571, Blast_Score=184, Evalue=5e-48,
Organism=Escherichia coli, GI1788069, Length=252, Percent_Identity=29.3650793650794, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1789059, Length=249, Percent_Identity=30.9236947791165, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789519, Length=244, Percent_Identity=27.8688524590164, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI226510968, Length=235, Percent_Identity=30.6382978723404, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790753, Length=230, Percent_Identity=27.3913043478261, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789170, Length=229, Percent_Identity=24.0174672489083, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787063, Length=235, Percent_Identity=23.8297872340426, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787540, Length=230, Percent_Identity=26.5217391304348, Blast_Score=74, Evalue=8e-15,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27803; Mature: 27803

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLTDRQTEIVAIAKSSGRVLVEELASRFSVTPQTIRKDLNDLCDAQVLTRIHGGATFPS
CCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GTENVKYEARRQIAASEKQAIGMAAVELIPSGASLFINIGTTTEAVGEALANHHELMVIT
CCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCHHHHHHHHHCCCEEEEEE
NNINVANRLRLFPAIEVVIAGGVVRGSDGGIVGEAAVDFIRQFKVDYAVIGASAIDIDGA
CCCCHHHHHHHHHHEEEEEECCEEECCCCCEEHHHHHHHHHHHCCCEEEECCEEEECCCE
LLDYDFREVKVAQAIIANARHVILVADSTKFERTAPVRIGQLSQVHTFITDHCPVPSIRN
EECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEECCCHHHHHHHHHCCCCCCHHHH
LCLENNVKLIETNSRSR
HHHCCCEEEEECCCCCC
>Mature Secondary Structure
MFLTDRQTEIVAIAKSSGRVLVEELASRFSVTPQTIRKDLNDLCDAQVLTRIHGGATFPS
CCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GTENVKYEARRQIAASEKQAIGMAAVELIPSGASLFINIGTTTEAVGEALANHHELMVIT
CCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCHHHHHHHHHCCCEEEEEE
NNINVANRLRLFPAIEVVIAGGVVRGSDGGIVGEAAVDFIRQFKVDYAVIGASAIDIDGA
CCCCHHHHHHHHHHEEEEEECCEEECCCCCEEHHHHHHHHHHHCCCEEEECCEEEECCCE
LLDYDFREVKVAQAIIANARHVILVADSTKFERTAPVRIGQLSQVHTFITDHCPVPSIRN
EECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEECCCHHHHHHHHHCCCCCCHHHH
LCLENNVKLIETNSRSR
HHHCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]