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The map label for this gene is galE [C]

Identifier: 190894633

GI number: 190894633

Start: 319474

End: 320577

Strand: Reverse

Name: galE [C]

Synonym: RHECIAT_PC0000296

Alternate gene names: 190894633

Gene position: 320577-319474 (Counterclockwise)

Preceding gene: 190894636

Following gene: 190894632

Centisome position: 29.37

GC content: 59.87

Gene sequence:

>1104_bases
ATGACGATCTTGATAACAGGTGGGTGCGGCTTTATTGGCCGCCATGTTGCTGCAGAACTTCTGCAAAGCGGCTATGATGT
GCGCATCCTCGATGCCTTGATCGACCAGGTGCATGCCGACGCCGAGATTGTCGTGCCGGAGGGTGCCGAGGTCGTTCGCG
GTGACGTCAGGGACAAGGACGCAGTGCGCGCGGCGCTCGCAAATGTCGACGGCGTCATCCATCTTGCCGCCGAAGTCGGC
GTTGGGCAATCAATGTATGAAATTGCCCGTTATGTCGGCTGCAACGACCTCGGAACGGCAGTGCTGCTCGAAACGATGAT
CGGCATGCCTGTCGGAAAGATCGTCGTCGCTTCCTCCATGAGCGTTTATGGAGAAGGGCTTTATCTGACCGCAGGCGGCA
GACGGCTCGGATATGTCAGGCGGCGCAGCCATCATATCAAGCGTGGCGAATGGGATCCGCTCGGACCCGATGATGAGCCG
TTGACCCCCGTCGCCACCGACGAGGAGAAGCCGGTCGATCTGGCTTCGATCTACGCCTTGACGAAATATGCTCAGGAGAA
ACAGGTCCTGATCTTCGGCGAAGCCTATCGTCTGGATGCCGTTGCCCTGCGTCTGTTCAATGTTTTTGGCGCCGGCCAAG
CCCTTTCCAACCCCTATACCGGCGTGCTCGCAAATTTCGGCTCGCGGCTGGCCAACGGGCAGCCGCCGATGATCTTCGAG
GACGGCAAGCAGCGGCGCGATTTCGTCCATGTGCGCGACGTGGCGAGGGCTTTCCGACTTGCCCTGGAGAAGCCCGCGGC
ATCGGGCCACGTGATCAATATCGGCAGCGGCCAGGCCTATTCGATCGCAGACGTTGCAACGCTTCTTGCCGACGCGATGG
GCGTTCCGGAGATCGCCCCCGATATTATGAACAAGGCGCGTTCCGGCGACATTCGCAATTGCTTTGCCGATATCTCCAAG
GCACGTGAACTGCTCGGCTTCGAGCCCAGATACCATCTCGAAAATTCGCTCGGTCCTTTCGTCGACTGGGTCCGGCAAAC
GGGGGCGATCGACCGCGGCGCCGAGATGAAGCGGCAACTGGAAGAACGGGGGCTGGTTTCATGA

Upstream 100 bases:

>100_bases
ATGAAGTCAATAAAGATGTCATTGAAGAAGGAACTTTTCCACCTACGCTCGGTTCGGCCGCTATCTCCGAAGCAATTTCT
TCAACCGGACGGATCCAATA

Downstream 100 bases:

>100_bases
ACAGGACCGGTTCTCGAGGATCCAGCCAGCGGGAGACTCGGCGCTTCGGCTTCGTCGAATGGTTCAGACCGGGAGAACAT
GAGCGGGCCGAGACACTGCT

Product: putative UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MTILITGGCGFIGRHVAAELLQSGYDVRILDALIDQVHADAEIVVPEGAEVVRGDVRDKDAVRAALANVDGVIHLAAEVG
VGQSMYEIARYVGCNDLGTAVLLETMIGMPVGKIVVASSMSVYGEGLYLTAGGRRLGYVRRRSHHIKRGEWDPLGPDDEP
LTPVATDEEKPVDLASIYALTKYAQEKQVLIFGEAYRLDAVALRLFNVFGAGQALSNPYTGVLANFGSRLANGQPPMIFE
DGKQRRDFVHVRDVARAFRLALEKPAASGHVINIGSGQAYSIADVATLLADAMGVPEIAPDIMNKARSGDIRNCFADISK
ARELLGFEPRYHLENSLGPFVDWVRQTGAIDRGAEMKRQLEERGLVS

Sequences:

>Translated_367_residues
MTILITGGCGFIGRHVAAELLQSGYDVRILDALIDQVHADAEIVVPEGAEVVRGDVRDKDAVRAALANVDGVIHLAAEVG
VGQSMYEIARYVGCNDLGTAVLLETMIGMPVGKIVVASSMSVYGEGLYLTAGGRRLGYVRRRSHHIKRGEWDPLGPDDEP
LTPVATDEEKPVDLASIYALTKYAQEKQVLIFGEAYRLDAVALRLFNVFGAGQALSNPYTGVLANFGSRLANGQPPMIFE
DGKQRRDFVHVRDVARAFRLALEKPAASGHVINIGSGQAYSIADVATLLADAMGVPEIAPDIMNKARSGDIRNCFADISK
ARELLGFEPRYHLENSLGPFVDWVRQTGAIDRGAEMKRQLEERGLVS
>Mature_366_residues
TILITGGCGFIGRHVAAELLQSGYDVRILDALIDQVHADAEIVVPEGAEVVRGDVRDKDAVRAALANVDGVIHLAAEVGV
GQSMYEIARYVGCNDLGTAVLLETMIGMPVGKIVVASSMSVYGEGLYLTAGGRRLGYVRRRSHHIKRGEWDPLGPDDEPL
TPVATDEEKPVDLASIYALTKYAQEKQVLIFGEAYRLDAVALRLFNVFGAGQALSNPYTGVLANFGSRLANGQPPMIFED
GKQRRDFVHVRDVARAFRLALEKPAASGHVINIGSGQAYSIADVATLLADAMGVPEIAPDIMNKARSGDIRNCFADISKA
RELLGFEPRYHLENSLGPFVDWVRQTGAIDRGAEMKRQLEERGLVS

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=349, Percent_Identity=26.3610315186246, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI7657641, Length=357, Percent_Identity=24.9299719887955, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1786974, Length=353, Percent_Identity=30.028328611898, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1788353, Length=365, Percent_Identity=25.7534246575342, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=392, Percent_Identity=27.5510204081633, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI19923002, Length=357, Percent_Identity=29.1316526610644, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI21356223, Length=346, Percent_Identity=26.0115606936416, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 39729; Mature: 39598

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILITGGCGFIGRHVAAELLQSGYDVRILDALIDQVHADAEIVVPEGAEVVRGDVRDKD
CEEEEECCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCEEECCCCHHHHHCCCCCHH
AVRAALANVDGVIHLAAEVGVGQSMYEIARYVGCNDLGTAVLLETMIGMPVGKIVVASSM
HHHHHHHCCCHHEEEHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHH
SVYGEGLYLTAGGRRLGYVRRRSHHIKRGEWDPLGPDDEPLTPVATDEEKPVDLASIYAL
HHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
TKYAQEKQVLIFGEAYRLDAVALRLFNVFGAGQALSNPYTGVLANFGSRLANGQPPMIFE
HHHHCCCEEEEEECHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHCCCCCCEEEC
DGKQRRDFVHVRDVARAFRLALEKPAASGHVINIGSGQAYSIADVATLLADAMGVPEIAP
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCH
DIMNKARSGDIRNCFADISKARELLGFEPRYHLENSLGPFVDWVRQTGAIDRGAEMKRQL
HHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHCCCCCCHHHHHHH
EERGLVS
HHCCCCC
>Mature Secondary Structure 
TILITGGCGFIGRHVAAELLQSGYDVRILDALIDQVHADAEIVVPEGAEVVRGDVRDKD
EEEEECCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCEEECCCCHHHHHCCCCCHH
AVRAALANVDGVIHLAAEVGVGQSMYEIARYVGCNDLGTAVLLETMIGMPVGKIVVASSM
HHHHHHHCCCHHEEEHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHH
SVYGEGLYLTAGGRRLGYVRRRSHHIKRGEWDPLGPDDEPLTPVATDEEKPVDLASIYAL
HHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
TKYAQEKQVLIFGEAYRLDAVALRLFNVFGAGQALSNPYTGVLANFGSRLANGQPPMIFE
HHHHCCCEEEEEECHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHCCCCCCEEEC
DGKQRRDFVHVRDVARAFRLALEKPAASGHVINIGSGQAYSIADVATLLADAMGVPEIAP
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCH
DIMNKARSGDIRNCFADISKARELLGFEPRYHLENSLGPFVDWVRQTGAIDRGAEMKRQL
HHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHCCCCCCHHHHHHH
EERGLVS
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]