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The map label for this gene is galE [C]

Identifier: 190894599

GI number: 190894599

Start: 278871

End: 279845

Strand: Reverse

Name: galE [C]

Synonym: RHECIAT_PC0000262

Alternate gene names: 190894599

Gene position: 279845-278871 (Counterclockwise)

Preceding gene: 190894600

Following gene: 190894598

Centisome position: 25.64

GC content: 58.77

Gene sequence:

>975_bases
ATGAGAAACAAACGGGTACTCATTACCGGCGGTGCCGGTCTGATCGGTTCGCATATTGCCGATCTCGTTGCATTGGAAAA
ACCTCGCGAGATCATCATCCTCGACAATTTCGTGCGCGGGCGCCGGGACAATCTGAGCTCGGCAATCGGCAGCGCGCCGC
TTAACATCATCGACGGCGATATCCGCGACAGGTCGCTGCTGGCGAAAGCCTTCGACGGCGTCGATATCGTCTTTCATCAG
GCGGCCATCCGCATAACCCAATGCGCGGAAGAGCCACGACTGGCTTTCGAAGTGCTGGCCGAAGGCACATTCAATGTCCT
CGAAGCGGCCGTCAAGGCGGGTGTTTCGAAGGTCGTCGCGGCCTCTTCCGCCTCCGTGCTGGGCCTTGCCGAAAGCTTTC
CGACGACCGAACAGCATCATCCCTACAATAACCGGACGATCTACGGCGCAGCAAAGACCTTCAACGAGGGATTGCTGCGC
AGCTTCGCGGACATGTATGGCCTACGCTATGTCGCGCTGCGCTATTTCAACGTCTACGGGCCACGAATGGACGTTTACGG
CGCCTACACCGAAGTGCTGATCCGCTGGATGGAACGCCTTGCAGCCGGAATGCCGCCGCTCATCTATGGAGACGGCAGCC
AAACGATGGACTTCGTCGATGCACGCGACATCGCCCGGGCAAACCTGCTCGCGGCAAAGAGTGACGTTACCGACGAGGTG
TTCAACGTCGCGAGCGGCAGGGAAATAAGCCTGCTGGAACTCGCGCAGATGCTGAGCGACATCATGGGATCCTCGCTCGA
GCCGCAACACAAAGAGGCCCGCACGGTCAATGGCGTGACCCGTCGTCTGGCTGATATCAGCAAGGCTGAAAAACTTCTGG
GTTTCAAGGCCGAAATCTCGATGGAGCAGGGGCTTCGTGACCTTGTCGAGTGGTGGCAGTCAAAGACTGCTGCAGCCGGA
GGTCAAGCCGCATGA

Upstream 100 bases:

>100_bases
ACGTCGAGCCCTTCTCGGTTGTCGCAGGAGTTCCTGCGAAATTAATTCGTTGGCGTTCGGAGAATGATCCGATGACGAAC
ATGTCGCGTGAGGAAAGATC

Downstream 100 bases:

>100_bases
GCACGTCATTATCGACAATCCCTGTCGCCAAACCCGTCCTCGGAGAGGAAGAGGCAGAGGCCGCCCGCCGCGTTATTCTA
TCTGGATGGGTAACCCAGGG

Product: putative UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MRNKRVLITGGAGLIGSHIADLVALEKPREIIILDNFVRGRRDNLSSAIGSAPLNIIDGDIRDRSLLAKAFDGVDIVFHQ
AAIRITQCAEEPRLAFEVLAEGTFNVLEAAVKAGVSKVVAASSASVLGLAESFPTTEQHHPYNNRTIYGAAKTFNEGLLR
SFADMYGLRYVALRYFNVYGPRMDVYGAYTEVLIRWMERLAAGMPPLIYGDGSQTMDFVDARDIARANLLAAKSDVTDEV
FNVASGREISLLELAQMLSDIMGSSLEPQHKEARTVNGVTRRLADISKAEKLLGFKAEISMEQGLRDLVEWWQSKTAAAG
GQAA

Sequences:

>Translated_324_residues
MRNKRVLITGGAGLIGSHIADLVALEKPREIIILDNFVRGRRDNLSSAIGSAPLNIIDGDIRDRSLLAKAFDGVDIVFHQ
AAIRITQCAEEPRLAFEVLAEGTFNVLEAAVKAGVSKVVAASSASVLGLAESFPTTEQHHPYNNRTIYGAAKTFNEGLLR
SFADMYGLRYVALRYFNVYGPRMDVYGAYTEVLIRWMERLAAGMPPLIYGDGSQTMDFVDARDIARANLLAAKSDVTDEV
FNVASGREISLLELAQMLSDIMGSSLEPQHKEARTVNGVTRRLADISKAEKLLGFKAEISMEQGLRDLVEWWQSKTAAAG
GQAA
>Mature_324_residues
MRNKRVLITGGAGLIGSHIADLVALEKPREIIILDNFVRGRRDNLSSAIGSAPLNIIDGDIRDRSLLAKAFDGVDIVFHQ
AAIRITQCAEEPRLAFEVLAEGTFNVLEAAVKAGVSKVVAASSASVLGLAESFPTTEQHHPYNNRTIYGAAKTFNEGLLR
SFADMYGLRYVALRYFNVYGPRMDVYGAYTEVLIRWMERLAAGMPPLIYGDGSQTMDFVDARDIARANLLAAKSDVTDEV
FNVASGREISLLELAQMLSDIMGSSLEPQHKEARTVNGVTRRLADISKAEKLLGFKAEISMEQGLRDLVEWWQSKTAAAG
GQAA

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=323, Percent_Identity=28.4829721362229, Blast_Score=131, Evalue=6e-31,
Organism=Homo sapiens, GI7657641, Length=329, Percent_Identity=29.1793313069909, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI56237023, Length=349, Percent_Identity=26.3610315186246, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI56118217, Length=349, Percent_Identity=26.3610315186246, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI189083684, Length=349, Percent_Identity=26.3610315186246, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1786974, Length=342, Percent_Identity=27.1929824561404, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI48994969, Length=336, Percent_Identity=27.0833333333333, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1788353, Length=342, Percent_Identity=25.7309941520468, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790049, Length=261, Percent_Identity=26.0536398467433, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788589, Length=341, Percent_Identity=22.8739002932551, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788365, Length=230, Percent_Identity=25.2173913043478, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17539532, Length=323, Percent_Identity=26.9349845201238, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17568069, Length=325, Percent_Identity=26.1538461538462, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=26.0869565217391, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=25.9365994236311, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115532424, Length=325, Percent_Identity=24.6153846153846, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=340, Percent_Identity=25.5882352941176, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21356223, Length=325, Percent_Identity=28, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI19923002, Length=349, Percent_Identity=28.080229226361, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35365; Mature: 35365

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNKRVLITGGAGLIGSHIADLVALEKPREIIILDNFVRGRRDNLSSAIGSAPLNIIDGD
CCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEECHHHCCCHHHHHHHHCCCCCEEECCC
IRDRSLLAKAFDGVDIVFHQAAIRITQCAEEPRLAFEVLAEGTFNVLEAAVKAGVSKVVA
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
ASSASVLGLAESFPTTEQHHPYNNRTIYGAAKTFNEGLLRSFADMYGLRYVALRYFNVYG
HCCCHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PRMDVYGAYTEVLIRWMERLAAGMPPLIYGDGSQTMDFVDARDIARANLLAAKSDVTDEV
CCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHH
FNVASGREISLLELAQMLSDIMGSSLEPQHKEARTVNGVTRRLADISKAEKLLGFKAEIS
HHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
MEQGLRDLVEWWQSKTAAAGGQAA
HHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRNKRVLITGGAGLIGSHIADLVALEKPREIIILDNFVRGRRDNLSSAIGSAPLNIIDGD
CCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEECHHHCCCHHHHHHHHCCCCCEEECCC
IRDRSLLAKAFDGVDIVFHQAAIRITQCAEEPRLAFEVLAEGTFNVLEAAVKAGVSKVVA
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
ASSASVLGLAESFPTTEQHHPYNNRTIYGAAKTFNEGLLRSFADMYGLRYVALRYFNVYG
HCCCHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PRMDVYGAYTEVLIRWMERLAAGMPPLIYGDGSQTMDFVDARDIARANLLAAKSDVTDEV
CCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHH
FNVASGREISLLELAQMLSDIMGSSLEPQHKEARTVNGVTRRLADISKAEKLLGFKAEIS
HHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
MEQGLRDLVEWWQSKTAAAGGQAA
HHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]