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The map label for this gene is dinB [H]

Identifier: 190894484

GI number: 190894484

Start: 140960

End: 142048

Strand: Reverse

Name: dinB [H]

Synonym: RHECIAT_PC0000146

Alternate gene names: 190894484

Gene position: 142048-140960 (Counterclockwise)

Preceding gene: 190894488

Following gene: 190894483

Centisome position: 13.01

GC content: 59.87

Gene sequence:

>1089_bases
ATGAATGAGATGAGTGCATCTTCCGTCCGAAAAATCGTCCACATCGACATGGATGCGTTTTATGCGTCGGTTGAGCAGCG
AGACAATCAGGACTTGCGGGGCAAGCCGATTGCCGTCGGTGGATCGGCCGCCCGCGGCGTGGTGGCGGCGGCGAGCTACG
AGGCACGTGCGTACGGCGTTCACTCGGCCATGCCATCAGTCACCGCCAAGCGCAAATGCCCGGAGCTGATATTCGTGGCG
CCGCGGTTCGACGTCTACAAGGCGGTGTCGCAGCAGATCCGCGAGATCTTCGCCGAATACACGGCCGTCATCGAGCCGCT
TTCTCTCGATGAAGCCTATCTCGACGTTACCCATAATCTCAAGGGCATGGAAATCGCCACGGAGATCGCACTGGAGATCC
GTGCCAAAATCAAGCAGGCCACTGGCCTCAATGCATCGGCGGGGATTTCCTACAACAAGTTCCTCGCCAAGATGGCGAGC
GACCTCAACAAGCCGAATGGCCAGGCGGTCATCACCCCGAAGAACGGTCCGGCCTTCGTCGAGGCCCTCCCCGTCAAGAA
ATTTCATGGCGTCGGCCCGGCAACGGCCGACAAGATGCACCGGCTCGGAATCGATACCGGCGCCGACCTCAAGGGGAAGA
CACTCGAATTCCTGGTGGAGCATTTCGGCAAGTCAGGACCCTATTTCCATGGTATCGCGCGCGGCATCGACGAGCGTCAG
GTAAAGCCGAACCGAGTGCGCAAATCGGTCGGCGCCGAAGATACCTTCTCCCAGGACCTCCATGCCTATGAACCGGCTCG
CCAAGGTCTTCAGCCGCTGATCGAAAAGGTGTGGGGTTATTGCGAGGCCAATGGCATCGGCGCCAAGACGGTGACGCTCA
AGGTCAAATATGCAGACTTCCATCAGATCACCCGCAGCAAGACAGTTCCGACCCTCTTGCGGGGGATCACGGAGCTTGAA
GAGATAATCAGCCTGATGCTGGCGCCGATCTTTCCGCCCCGAAAGGGCATTCGGCTGCTCGGCATTACCCTGTCCTCGCT
GGAACGGCGGGCCTCTGGGACGGAGCCACAGCTGCGGTTGGCCCTCTAG

Upstream 100 bases:

>100_bases
GCTATTGCTTGGTTGATCTCGCGTTGAGGCCTGCTATGTTCTCCTTTTGTTTCGGACTCAATCTTGAGATGCCGATTCCA
TTGAGATCGCCGAAGCCGTC

Downstream 100 bases:

>100_bases
ACGCCAGCATCGGCTGGAGGAGAAGCTTCGGACCCGATGTGACCCACCGCGCTCGTGTGTCACAACCGCTTCATTGGAAG
GCTGGGAGCTCCGCGTCGAC

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV 2 [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MNEMSASSVRKIVHIDMDAFYASVEQRDNQDLRGKPIAVGGSAARGVVAAASYEARAYGVHSAMPSVTAKRKCPELIFVA
PRFDVYKAVSQQIREIFAEYTAVIEPLSLDEAYLDVTHNLKGMEIATEIALEIRAKIKQATGLNASAGISYNKFLAKMAS
DLNKPNGQAVITPKNGPAFVEALPVKKFHGVGPATADKMHRLGIDTGADLKGKTLEFLVEHFGKSGPYFHGIARGIDERQ
VKPNRVRKSVGAEDTFSQDLHAYEPARQGLQPLIEKVWGYCEANGIGAKTVTLKVKYADFHQITRSKTVPTLLRGITELE
EIISLMLAPIFPPRKGIRLLGITLSSLERRASGTEPQLRLAL

Sequences:

>Translated_362_residues
MNEMSASSVRKIVHIDMDAFYASVEQRDNQDLRGKPIAVGGSAARGVVAAASYEARAYGVHSAMPSVTAKRKCPELIFVA
PRFDVYKAVSQQIREIFAEYTAVIEPLSLDEAYLDVTHNLKGMEIATEIALEIRAKIKQATGLNASAGISYNKFLAKMAS
DLNKPNGQAVITPKNGPAFVEALPVKKFHGVGPATADKMHRLGIDTGADLKGKTLEFLVEHFGKSGPYFHGIARGIDERQ
VKPNRVRKSVGAEDTFSQDLHAYEPARQGLQPLIEKVWGYCEANGIGAKTVTLKVKYADFHQITRSKTVPTLLRGITELE
EIISLMLAPIFPPRKGIRLLGITLSSLERRASGTEPQLRLAL
>Mature_362_residues
MNEMSASSVRKIVHIDMDAFYASVEQRDNQDLRGKPIAVGGSAARGVVAAASYEARAYGVHSAMPSVTAKRKCPELIFVA
PRFDVYKAVSQQIREIFAEYTAVIEPLSLDEAYLDVTHNLKGMEIATEIALEIRAKIKQATGLNASAGISYNKFLAKMAS
DLNKPNGQAVITPKNGPAFVEALPVKKFHGVGPATADKMHRLGIDTGADLKGKTLEFLVEHFGKSGPYFHGIARGIDERQ
VKPNRVRKSVGAEDTFSQDLHAYEPARQGLQPLIEKVWGYCEANGIGAKTVTLKVKYADFHQITRSKTVPTLLRGITELE
EIISLMLAPIFPPRKGIRLLGITLSSLERRASGTEPQLRLAL

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI7706681, Length=339, Percent_Identity=33.0383480825959, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI84043967, Length=338, Percent_Identity=31.9526627218935, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI7705344, Length=119, Percent_Identity=51.2605042016807, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI5729982, Length=325, Percent_Identity=29.5384615384615, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI154350220, Length=327, Percent_Identity=28.4403669724771, Blast_Score=125, Evalue=6e-29,
Organism=Escherichia coli, GI1786425, Length=360, Percent_Identity=43.8888888888889, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI1787432, Length=218, Percent_Identity=32.1100917431193, Blast_Score=96, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI193205700, Length=409, Percent_Identity=31.2958435207824, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17537959, Length=267, Percent_Identity=32.9588014981273, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI193205702, Length=267, Percent_Identity=32.9588014981273, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI115534089, Length=139, Percent_Identity=38.1294964028777, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324921, Length=206, Percent_Identity=27.6699029126214, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19923006, Length=413, Percent_Identity=28.3292978208232, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI21355641, Length=313, Percent_Identity=29.7124600638978, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24644984, Length=313, Percent_Identity=29.7124600638978, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24668444, Length=251, Percent_Identity=28.2868525896414, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39567; Mature: 39567

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEMSASSVRKIVHIDMDAFYASVEQRDNQDLRGKPIAVGGSAARGVVAAASYEARAYGV
CCCCCHHHHHHHHEECHHHHHHHHHHCCCCCCCCCCEEECCCHHCCEEEECCCCHHHHHH
HSAMPSVTAKRKCPELIFVAPRFDVYKAVSQQIREIFAEYTAVIEPLSLDEAYLDVTHNL
HHHCCCHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCC
KGMEIATEIALEIRAKIKQATGLNASAGISYNKFLAKMASDLNKPNGQAVITPKNGPAFV
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCEE
EALPVKKFHGVGPATADKMHRLGIDTGADLKGKTLEFLVEHFGKSGPYFHGIARGIDERQ
EEECHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCC
VKPNRVRKSVGAEDTFSQDLHAYEPARQGLQPLIEKVWGYCEANGIGAKTVTLKVKYADF
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECHH
HQITRSKTVPTLLRGITELEEIISLMLAPIFPPRKGIRLLGITLSSLERRASGTEPQLRL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHCCCCCCEEE
AL
CC
>Mature Secondary Structure
MNEMSASSVRKIVHIDMDAFYASVEQRDNQDLRGKPIAVGGSAARGVVAAASYEARAYGV
CCCCCHHHHHHHHEECHHHHHHHHHHCCCCCCCCCCEEECCCHHCCEEEECCCCHHHHHH
HSAMPSVTAKRKCPELIFVAPRFDVYKAVSQQIREIFAEYTAVIEPLSLDEAYLDVTHNL
HHHCCCHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCC
KGMEIATEIALEIRAKIKQATGLNASAGISYNKFLAKMASDLNKPNGQAVITPKNGPAFV
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCEE
EALPVKKFHGVGPATADKMHRLGIDTGADLKGKTLEFLVEHFGKSGPYFHGIARGIDERQ
EEECHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCC
VKPNRVRKSVGAEDTFSQDLHAYEPARQGLQPLIEKVWGYCEANGIGAKTVTLKVKYADF
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECHH
HQITRSKTVPTLLRGITELEEIISLMLAPIFPPRKGIRLLGITLSSLERRASGTEPQLRL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHCCCCCCEEE
AL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]