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The map label for this gene is plsC [H]

Identifier: 190571373

GI number: 190571373

Start: 1049301

End: 1050026

Strand: Direct

Name: plsC [H]

Synonym: WPa_0981

Alternate gene names: 190571373

Gene position: 1049301-1050026 (Clockwise)

Preceding gene: 190571372

Following gene: 190571374

Centisome position: 70.78

GC content: 30.58

Gene sequence:

>726_bases
GTGATTGCAAGTTTATTGTTTAATTTACTCCTTATATTATGGGAAGTATTCTATACTTTAATTACTCTCCCTGTAATTTT
CTTTCCTGAGTGTGTAATAACCATTTTCCTTGTTTGCTCGGTGAGAGTTGTATTATTCATGTTGCGTTTATTATGTGGCA
TTAAATATGAAGTGAGGGGAATGGAAAACATTCCTAAGCAACCTTTTATAATTGCATCTAAACACCAATCTCCATTTGAA
ACATTTATTTTTATACTACTCTTTAGAAAAGCAGTTTTTATTTTAAAACGTGAATTGAAATGGATTCCATTCATTGGTTT
ACATCTTATAGCGCTGAAAATGATTTTTATTAACCGTTCAGATGGTATCAGTTCTATACGCCATATAATTAAACTAGCAA
AAATGCATATAAAAGAAAATAGAAGCATAATAATATTTCCTGAAGGCACAAGAACGACTATAAACCAAAATATAAAATAT
CAATCGGGTATTGCTGCTTTATATAGCGTATTATCTGTTCCTGTGTTACCGATTGCTTTAAACACTGGTTTGTTTTGGCC
AAAAAGCATACTTTCTCTGAGAAAGAATCCCGGAAAGGCGGTAATAGAAATATTACCTCCCATATATCCTGGGTTAAACA
AAAATGAATTCTTGCAAAGTTTAGAAAAAATCATTGAAGAAAGAAGTAGTAGATTAATTGCAGAAAAAACTGATATTGCA
AATTAA

Upstream 100 bases:

>100_bases
AATTAGCTGATTCTCATCCTATTACTCAGATGATCAATAATTAAACTTATTGCTTTTAGTTTTGTAGTAAAGTTAAATTC
AAATAAGTTTACGTGTGTTT

Downstream 100 bases:

>100_bases
CAAAAAAACTTTATAATTAAAAGAAAAGTACAGGTATTAATATATGGCAAATCATAAGAGTGCTAAAAAAATGATGAAGG
TAATAGCAAAGCGTACTTTA

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase family protein

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MIASLLFNLLLILWEVFYTLITLPVIFFPECVITIFLVCSVRVVLFMLRLLCGIKYEVRGMENIPKQPFIIASKHQSPFE
TFIFILLFRKAVFILKRELKWIPFIGLHLIALKMIFINRSDGISSIRHIIKLAKMHIKENRSIIIFPEGTRTTINQNIKY
QSGIAALYSVLSVPVLPIALNTGLFWPKSILSLRKNPGKAVIEILPPIYPGLNKNEFLQSLEKIIEERSSRLIAEKTDIA
N

Sequences:

>Translated_241_residues
MIASLLFNLLLILWEVFYTLITLPVIFFPECVITIFLVCSVRVVLFMLRLLCGIKYEVRGMENIPKQPFIIASKHQSPFE
TFIFILLFRKAVFILKRELKWIPFIGLHLIALKMIFINRSDGISSIRHIIKLAKMHIKENRSIIIFPEGTRTTINQNIKY
QSGIAALYSVLSVPVLPIALNTGLFWPKSILSLRKNPGKAVIEILPPIYPGLNKNEFLQSLEKIIEERSSRLIAEKTDIA
N
>Mature_241_residues
MIASLLFNLLLILWEVFYTLITLPVIFFPECVITIFLVCSVRVVLFMLRLLCGIKYEVRGMENIPKQPFIIASKHQSPFE
TFIFILLFRKAVFILKRELKWIPFIGLHLIALKMIFINRSDGISSIRHIIKLAKMHIKENRSIIIFPEGTRTTINQNIKY
QSGIAALYSVLSVPVLPIALNTGLFWPKSILSLRKNPGKAVIEILPPIYPGLNKNEFLQSLEKIIEERSSRLIAEKTDIA
N

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=201, Percent_Identity=28.3582089552239, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI15100175, Length=201, Percent_Identity=28.3582089552239, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17568319, Length=191, Percent_Identity=23.5602094240838, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6320151, Length=194, Percent_Identity=26.2886597938144, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281364648, Length=203, Percent_Identity=29.5566502463054, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24582856, Length=203, Percent_Identity=29.5566502463054, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24582854, Length=203, Percent_Identity=29.5566502463054, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24641614, Length=201, Percent_Identity=28.3582089552239, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641612, Length=201, Percent_Identity=28.3582089552239, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 27677; Mature: 27677

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIASLLFNLLLILWEVFYTLITLPVIFFPECVITIFLVCSVRVVLFMLRLLCGIKYEVRG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCC
MENIPKQPFIIASKHQSPFETFIFILLFRKAVFILKRELKWIPFIGLHLIALKMIFINRS
CCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
DGISSIRHIIKLAKMHIKENRSIIIFPEGTRTTINQNIKYQSGIAALYSVLSVPVLPIAL
CCHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHCCCCCHHHHHHHHHHHHHCCHHHHHH
NTGLFWPKSILSLRKNPGKAVIEILPPIYPGLNKNEFLQSLEKIIEERSSRLIAEKTDIA
CCCCCCHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
N
C
>Mature Secondary Structure
MIASLLFNLLLILWEVFYTLITLPVIFFPECVITIFLVCSVRVVLFMLRLLCGIKYEVRG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCC
MENIPKQPFIIASKHQSPFETFIFILLFRKAVFILKRELKWIPFIGLHLIALKMIFINRS
CCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
DGISSIRHIIKLAKMHIKENRSIIIFPEGTRTTINQNIKYQSGIAALYSVLSVPVLPIAL
CCHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHCCCCCHHHHHHHHHHHHHCCHHHHHH
NTGLFWPKSILSLRKNPGKAVIEILPPIYPGLNKNEFLQSLEKIIEERSSRLIAEKTDIA
CCCCCCHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685; 7812434 [H]