Click here to switch to the map view.

The map label for this gene is xerD [H]

Identifier: 190571372

GI number: 190571372

Start: 1048258

End: 1049244

Strand: Direct

Name: xerD [H]

Synonym: WPa_0980

Alternate gene names: 190571372

Gene position: 1048258-1049244 (Clockwise)

Preceding gene: 190571371

Following gene: 190571373

Centisome position: 70.71

GC content: 30.7

Gene sequence:

>987_bases
ATGAAAAATAAACAACCACAAAATAAAAAAGAGAATCTTTACATCACGTATTACATAGATGCTTTGGTTTCTGAAAAATC
CTCTACACAAAATACTTTGGAAAGTTATCGTTCAGATTTACACCAACTTGAAAAATTTTTATTAGAAGGAGGCACTACCT
TAGTTGGTGCAAGTAAAGCTAATATTAAAGATTATGTAAACTTTTTACGTACACAAAAGAAATATAAAACTAGTTCTATA
TCAAGAAAAATATCTGCTATCAAAAATTTCTATAAGTGCCTATTTAATGATGGAATAATAGATTTTAATCCAGCACCGGC
TAATGATAATGAATTAAGAAATCCAAAGGTTTCCCGTCCTTTGCCTAAGTATTTAAGTGTTCAAGAAATATTTTTGCTCA
TGGAAACAGTAAAAAAATCAGCAAGCGGATCGAATAAAGAGATAAGCAGTAAAAGGCTATGTGCAATTTTAGATATTCTT
TACTCTTCCGGGATGCGTGTTTCTGAACTAATTAATATGAAGTTATGTGAAGTATTACATTTAGTAAACGGTAATGGTAA
AGAAGGCTATATAATAATAAAGGGAAAAAGTAGCAGAGAAAGGCAAATCCTTTTTAATGAGCAAGCATTGCAAAGTCTTA
AAAATTATTTATCAATTCGTGACAATCTGCTTCCTAACAACAAAAAATCTGATTGGCTATTCCCAGGTGATAAACCTAAT
AAACCCATTACAAGGCAAAGAGTTGGTCAATTAATAAAGGAATTAGCAAGAAAGTGCGATATTGATGAAAATAAAATCTC
TCCACATGTGATTAGGCATTCTCTTGCTACCCATCTACTGAATAGCGGAGCAAATATTGTGCTGATACAAAAAATTCTTG
GCCATACTAATCTTTCTACAACACAAATATATACTCATATTGCTAATGAAAAGTTAAAGGACAAATTAGCTGATTCTCAT
CCTATTACTCAGATGATCAATAATTAA

Upstream 100 bases:

>100_bases
TTATTGATAAATGCTTTGTTTATCTCATATTTTCTTATAAAAAACACAAAAAATACTTTCAATCAAATTATAGTCAAAGA
AATAAATATAGGAGCTGATA

Downstream 100 bases:

>100_bases
ACTTATTGCTTTTAGTTTTGTAGTAAAGTTAAATTCAAATAAGTTTACGTGTGTTTGTGATTGCAAGTTTATTGTTTAAT
TTACTCCTTATATTATGGGA

Product: site-specific recombinase, phage integrase family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MKNKQPQNKKENLYITYYIDALVSEKSSTQNTLESYRSDLHQLEKFLLEGGTTLVGASKANIKDYVNFLRTQKKYKTSSI
SRKISAIKNFYKCLFNDGIIDFNPAPANDNELRNPKVSRPLPKYLSVQEIFLLMETVKKSASGSNKEISSKRLCAILDIL
YSSGMRVSELINMKLCEVLHLVNGNGKEGYIIIKGKSSRERQILFNEQALQSLKNYLSIRDNLLPNNKKSDWLFPGDKPN
KPITRQRVGQLIKELARKCDIDENKISPHVIRHSLATHLLNSGANIVLIQKILGHTNLSTTQIYTHIANEKLKDKLADSH
PITQMINN

Sequences:

>Translated_328_residues
MKNKQPQNKKENLYITYYIDALVSEKSSTQNTLESYRSDLHQLEKFLLEGGTTLVGASKANIKDYVNFLRTQKKYKTSSI
SRKISAIKNFYKCLFNDGIIDFNPAPANDNELRNPKVSRPLPKYLSVQEIFLLMETVKKSASGSNKEISSKRLCAILDIL
YSSGMRVSELINMKLCEVLHLVNGNGKEGYIIIKGKSSRERQILFNEQALQSLKNYLSIRDNLLPNNKKSDWLFPGDKPN
KPITRQRVGQLIKELARKCDIDENKISPHVIRHSLATHLLNSGANIVLIQKILGHTNLSTTQIYTHIANEKLKDKLADSH
PITQMINN
>Mature_328_residues
MKNKQPQNKKENLYITYYIDALVSEKSSTQNTLESYRSDLHQLEKFLLEGGTTLVGASKANIKDYVNFLRTQKKYKTSSI
SRKISAIKNFYKCLFNDGIIDFNPAPANDNELRNPKVSRPLPKYLSVQEIFLLMETVKKSASGSNKEISSKRLCAILDIL
YSSGMRVSELINMKLCEVLHLVNGNGKEGYIIIKGKSSRERQILFNEQALQSLKNYLSIRDNLLPNNKKSDWLFPGDKPN
KPITRQRVGQLIKELARKCDIDENKISPHVIRHSLATHLLNSGANIVLIQKILGHTNLSTTQIYTHIANEKLKDKLADSH
PITQMINN

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=307, Percent_Identity=34.2019543973941, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1790244, Length=309, Percent_Identity=28.8025889967638, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790767, Length=157, Percent_Identity=30.5732484076433, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 37302; Mature: 37302

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKQPQNKKENLYITYYIDALVSEKSSTQNTLESYRSDLHQLEKFLLEGGTTLVGASKA
CCCCCCCCCCCCEEEEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
NIKDYVNFLRTQKKYKTSSISRKISAIKNFYKCLFNDGIIDFNPAPANDNELRNPKVSRP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCC
LPKYLSVQEIFLLMETVKKSASGSNKEISSKRLCAILDILYSSGMRVSELINMKLCEVLH
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LVNGNGKEGYIIIKGKSSRERQILFNEQALQSLKNYLSIRDNLLPNNKKSDWLFPGDKPN
HHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
KPITRQRVGQLIKELARKCDIDENKISPHVIRHSLATHLLNSGANIVLIQKILGHTNLST
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHCCCCCCH
TQIYTHIANEKLKDKLADSHPITQMINN
HHHHHHHHHHHHHHHHCCCCCHHHHHCC
>Mature Secondary Structure
MKNKQPQNKKENLYITYYIDALVSEKSSTQNTLESYRSDLHQLEKFLLEGGTTLVGASKA
CCCCCCCCCCCCEEEEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
NIKDYVNFLRTQKKYKTSSISRKISAIKNFYKCLFNDGIIDFNPAPANDNELRNPKVSRP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCC
LPKYLSVQEIFLLMETVKKSASGSNKEISSKRLCAILDILYSSGMRVSELINMKLCEVLH
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LVNGNGKEGYIIIKGKSSRERQILFNEQALQSLKNYLSIRDNLLPNNKKSDWLFPGDKPN
HHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
KPITRQRVGQLIKELARKCDIDENKISPHVIRHSLATHLLNSGANIVLIQKILGHTNLST
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHCCCCCCH
TQIYTHIANEKLKDKLADSHPITQMINN
HHHHHHHHHHHHHHHHCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]