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The map label for this gene is murG

Identifier: 190571295

GI number: 190571295

Start: 965191

End: 966213

Strand: Direct

Name: murG

Synonym: WPa_0898

Alternate gene names: 190571295

Gene position: 965191-966213 (Clockwise)

Preceding gene: 190571293

Following gene: 190571297

Centisome position: 65.11

GC content: 34.8

Gene sequence:

>1023_bases
ATGACTATTATTCTAGCAACAGGCGGTACAGGTGGGCATGTTTTTCCAGCTATAACCTTAGCAAAAGCACTAAAGGTACA
AGGGCACAATTGTATATTATTCACTGATCAAAAAACCATCAATATAGAAAGTTATATTTTACCATTGTGCAAGCCAAGTG
GCAACAAATTGAAGTTTCTCTTTTTGTTAATGTATAGTTGTGTATTAGCACTGTATCAAACGAGAAAATTAAAACCAAAG
CTAATCATTGGTTTTGGTAGCTACGCTTCTTTTCCAACTCTTCTTGCAGCAAAGATTCTTTCTATACCTATAGTTTTACA
TGAACAAAACACAGTTTTAGGGAGAGTAAATAGATTCTTTTTCAAGAGTGCAAAATTAATTGCAACTAGCTTTCCGGAGA
CTAAGTATGCAGAAGGTAGTAAATGCGTTTTTACAGGAAATTTTGTCGATATAGAAGCACAAGGCTATTCTAGAGCTGAA
ACAGTTTTAAACGTGTTAATAATAGCAGGCAGTCAGGGTGCAAATTTTTTTGATGATGTAGTGAGCAGCGTAATTTGTGA
TCTACCTGTTGAAGTAAAAGAGAGGATTAGAGTAACGCAGCAATGTACGAAGAAAAATATAAACAAGGTCAAGAGTCTAT
ACAAAAGTGAAGGAATTGATTGTGAGTTAAGTGAGTTTTTCGATGATATGGAAAATAAACTGGCCAATGCTCATTTGGTA
ATTAGCAGAGCGGGGGCAACTTCAATAGCAGAGATTACTCTTGCTGAGCGTCCTGCTGTATATATTCCTTATCCTCACTC
AAAAGATAACCATCAATTTTATAATGCAAAACATATTGAAGATTCGGGAGCAGCTGTAATGGTTGAGCAAAATAGTAACG
CGAAAAAGAATCTAGGAGAGTTGCTAGTTGATTTATTGCAAAATTGTCAAAAATTGCGTGATATGGCTAATAATACTAAG
AAAACAAGAATAAGGAATGGAGTTACTGAATTTATTAAGGCAATAGCTCAAGAACTTAGTTGA

Upstream 100 bases:

>100_bases
TTTAGGCATTTTTAACTCAACTATCATAAAGCTTGATAAAATTTTACATGCAAAGTATTAAAAAATAATTAACAATCTAT
TATCAAATTACTACTTACAG

Downstream 100 bases:

>100_bases
CGAATTGCTTTTTCTTCAAATGCATCCCATAGTTCTTTTTCTAGTGATTTACTATACAACTTATTGATATAAACTACTCC
CGTAGGCGAAGTTGTGTTAA

Product: UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTIILATGGTGGHVFPAITLAKALKVQGHNCILFTDQKTINIESYILPLCKPSGNKLKFLFLLMYSCVLALYQTRKLKPK
LIIGFGSYASFPTLLAAKILSIPIVLHEQNTVLGRVNRFFFKSAKLIATSFPETKYAEGSKCVFTGNFVDIEAQGYSRAE
TVLNVLIIAGSQGANFFDDVVSSVICDLPVEVKERIRVTQQCTKKNINKVKSLYKSEGIDCELSEFFDDMENKLANAHLV
ISRAGATSIAEITLAERPAVYIPYPHSKDNHQFYNAKHIEDSGAAVMVEQNSNAKKNLGELLVDLLQNCQKLRDMANNTK
KTRIRNGVTEFIKAIAQELS

Sequences:

>Translated_340_residues
MTIILATGGTGGHVFPAITLAKALKVQGHNCILFTDQKTINIESYILPLCKPSGNKLKFLFLLMYSCVLALYQTRKLKPK
LIIGFGSYASFPTLLAAKILSIPIVLHEQNTVLGRVNRFFFKSAKLIATSFPETKYAEGSKCVFTGNFVDIEAQGYSRAE
TVLNVLIIAGSQGANFFDDVVSSVICDLPVEVKERIRVTQQCTKKNINKVKSLYKSEGIDCELSEFFDDMENKLANAHLV
ISRAGATSIAEITLAERPAVYIPYPHSKDNHQFYNAKHIEDSGAAVMVEQNSNAKKNLGELLVDLLQNCQKLRDMANNTK
KTRIRNGVTEFIKAIAQELS
>Mature_339_residues
TIILATGGTGGHVFPAITLAKALKVQGHNCILFTDQKTINIESYILPLCKPSGNKLKFLFLLMYSCVLALYQTRKLKPKL
IIGFGSYASFPTLLAAKILSIPIVLHEQNTVLGRVNRFFFKSAKLIATSFPETKYAEGSKCVFTGNFVDIEAQGYSRAET
VLNVLIIAGSQGANFFDDVVSSVICDLPVEVKERIRVTQQCTKKNINKVKSLYKSEGIDCELSEFFDDMENKLANAHLVI
SRAGATSIAEITLAERPAVYIPYPHSKDNHQFYNAKHIEDSGAAVMVEQNSNAKKNLGELLVDLLQNCQKLRDMANNTKK
TRIRNGVTEFIKAIAQELS

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=358, Percent_Identity=29.8882681564246, Blast_Score=145, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_WOLPP (B3CM87)

Other databases:

- EMBL:   AM999887
- RefSeq:   YP_001975653.1
- EnsemblBacteria:   EBWOLT00000000646
- GeneID:   6385125
- GenomeReviews:   AM999887_GR
- KEGG:   wpi:WPa_0898
- GeneTree:   EBGT00050000030899
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   CLSK740297
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 37632; Mature: 37501

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIILATGGTGGHVFPAITLAKALKVQGHNCILFTDQKTINIESYILPLCKPSGNKLKFL
CEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEEHHHHEEEEECCCCCCHHHH
FLLMYSCVLALYQTRKLKPKLIIGFGSYASFPTLLAAKILSIPIVLHEQNTVLGRVNRFF
HHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHH
FKSAKLIATSFPETKYAEGSKCVFTGNFVDIEAQGYSRAETVLNVLIIAGSQGANFFDDV
HHHHHHEEECCCCCCCCCCCEEEEECCEEEEECCCCHHHHHHHEEEEEECCCCCCHHHHH
VSSVICDLPVEVKERIRVTQQCTKKNINKVKSLYKSEGIDCELSEFFDDMENKLANAHLV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCEEEE
ISRAGATSIAEITLAERPAVYIPYPHSKDNHQFYNAKHIEDSGAAVMVEQNSNAKKNLGE
EEECCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCEECCCCCEEEEECCCCHHHHHHH
LLVDLLQNCQKLRDMANNTKKTRIRNGVTEFIKAIAQELS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TIILATGGTGGHVFPAITLAKALKVQGHNCILFTDQKTINIESYILPLCKPSGNKLKFL
EEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEEHHHHEEEEECCCCCCHHHH
FLLMYSCVLALYQTRKLKPKLIIGFGSYASFPTLLAAKILSIPIVLHEQNTVLGRVNRFF
HHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHH
FKSAKLIATSFPETKYAEGSKCVFTGNFVDIEAQGYSRAETVLNVLIIAGSQGANFFDDV
HHHHHHEEECCCCCCCCCCCEEEEECCEEEEECCCCHHHHHHHEEEEEECCCCCCHHHHH
VSSVICDLPVEVKERIRVTQQCTKKNINKVKSLYKSEGIDCELSEFFDDMENKLANAHLV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCEEEE
ISRAGATSIAEITLAERPAVYIPYPHSKDNHQFYNAKHIEDSGAAVMVEQNSNAKKNLGE
EEECCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCEECCCCCEEEEECCCCHHHHHHH
LLVDLLQNCQKLRDMANNTKKTRIRNGVTEFIKAIAQELS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA