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The map label for this gene is pdxH [H]

Identifier: 190571280

GI number: 190571280

Start: 948511

End: 949104

Strand: Reverse

Name: pdxH [H]

Synonym: WPa_0881

Alternate gene names: 190571280

Gene position: 949104-948511 (Counterclockwise)

Preceding gene: 190571281

Following gene: 190571277

Centisome position: 64.02

GC content: 37.37

Gene sequence:

>594_bases
ATGACACTCTTACCTGAAAAAGATCCTTTTGATTTGTTCTCAAAGTGGTATCAAGAAGTACTTAATTTTCCGTGTAAAGA
GTCAACTGCAATGACGCTAGCAACGTGTAGCAAAGACTGCATTCCATCTGCAAGAGTGGTATTACTAAAGGAGTATAGTA
AAGAAGGTTTTGTGTTCTTTACTAACGTAAACAGTAGAAAAGGAAAAGAATTGACTGAGAACCCCAAAGCTGCACTCGTA
TTTCATTGGACAGAATTTTCTAGACAAGTACGAATTGAAGGAGAAGTTAGGCTTCTAAGCGGCAAAAAGGCTGACGAATA
TTTCTCTTCTCGAGCACGTGATAGTCAAATTAGCGCGTGGTGCTCAAAACAATCAAGAGTTCTGAAAAATTGGCAAGATT
TTGAGCAGGCTATAGAATTGAAAGAGAAAGAATTTCACAATACACAAGTTTCTCGTCCTGACTTTTGGGTGGGATTTTGC
GTAATCCCAAAGGTAATTGAATTTTGGCAAGAAGGTGAATATAGGAGACACACTAGATTTAGATATACTCTTGTTGAGAA
AAGCAATTGGAAAGTGGAACAATTATATCCCTAA

Upstream 100 bases:

>100_bases
ACCTTGCAGAATCTGCAACAATATCATAACACTTATACGACAAAATGGTCGTAGCACTTATTTTTGCAATGCATGTCAGA
ATTAAATTTTATTTTTGCAT

Downstream 100 bases:

>100_bases
CGTTAGAGAAAGCTACTCTGCAGATCAAAGATAAGGATTTATTGTCATAACAAGGAAAGTAACTTTTTATGGCTTGTTGT
ATGTAACGTTACGCAAAATA

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MTLLPEKDPFDLFSKWYQEVLNFPCKESTAMTLATCSKDCIPSARVVLLKEYSKEGFVFFTNVNSRKGKELTENPKAALV
FHWTEFSRQVRIEGEVRLLSGKKADEYFSSRARDSQISAWCSKQSRVLKNWQDFEQAIELKEKEFHNTQVSRPDFWVGFC
VIPKVIEFWQEGEYRRHTRFRYTLVEKSNWKVEQLYP

Sequences:

>Translated_197_residues
MTLLPEKDPFDLFSKWYQEVLNFPCKESTAMTLATCSKDCIPSARVVLLKEYSKEGFVFFTNVNSRKGKELTENPKAALV
FHWTEFSRQVRIEGEVRLLSGKKADEYFSSRARDSQISAWCSKQSRVLKNWQDFEQAIELKEKEFHNTQVSRPDFWVGFC
VIPKVIEFWQEGEYRRHTRFRYTLVEKSNWKVEQLYP
>Mature_196_residues
TLLPEKDPFDLFSKWYQEVLNFPCKESTAMTLATCSKDCIPSARVVLLKEYSKEGFVFFTNVNSRKGKELTENPKAALVF
HWTEFSRQVRIEGEVRLLSGKKADEYFSSRARDSQISAWCSKQSRVLKNWQDFEQAIELKEKEFHNTQVSRPDFWVGFCV
IPKVIEFWQEGEYRRHTRFRYTLVEKSNWKVEQLYP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=186, Percent_Identity=44.6236559139785, Blast_Score=155, Evalue=2e-38,
Organism=Escherichia coli, GI1787926, Length=191, Percent_Identity=42.4083769633508, Blast_Score=151, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17553712, Length=184, Percent_Identity=39.1304347826087, Blast_Score=134, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6319509, Length=197, Percent_Identity=37.5634517766497, Blast_Score=131, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24644901, Length=180, Percent_Identity=40.5555555555556, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI45551845, Length=180, Percent_Identity=40.5555555555556, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24644903, Length=188, Percent_Identity=25, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 23402; Mature: 23271

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLPEKDPFDLFSKWYQEVLNFPCKESTAMTLATCSKDCIPSARVVLLKEYSKEGFVFF
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEHHHCCCCCCCCHHEEEEEECCCCCEEEE
TNVNSRKGKELTENPKAALVFHWTEFSRQVRIEGEVRLLSGKKADEYFSSRARDSQISAW
EECCCCCCCCCCCCCCEEEEEEEECCCCEEEECCEEEEECCCCHHHHHHHHCCCHHHHHH
CSKQSRVLKNWQDFEQAIELKEKEFHNTQVSRPDFWVGFCVIPKVIEFWQEGEYRRHTRF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHCEE
RYTLVEKSNWKVEQLYP
EEEEEECCCCCEEECCC
>Mature Secondary Structure 
TLLPEKDPFDLFSKWYQEVLNFPCKESTAMTLATCSKDCIPSARVVLLKEYSKEGFVFF
CCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEHHHCCCCCCCCHHEEEEEECCCCCEEEE
TNVNSRKGKELTENPKAALVFHWTEFSRQVRIEGEVRLLSGKKADEYFSSRARDSQISAW
EECCCCCCCCCCCCCCEEEEEEEECCCCEEEECCEEEEECCCCHHHHHHHHCCCHHHHHH
CSKQSRVLKNWQDFEQAIELKEKEFHNTQVSRPDFWVGFCVIPKVIEFWQEGEYRRHTRF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHCEE
RYTLVEKSNWKVEQLYP
EEEEEECCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA