Click here to switch to the map view.

The map label for this gene is nuoA [H]

Identifier: 190571251

GI number: 190571251

Start: 927456

End: 927809

Strand: Direct

Name: nuoA [H]

Synonym: WPa_0852

Alternate gene names: 190571251

Gene position: 927456-927809 (Clockwise)

Preceding gene: 190571250

Following gene: 190571252

Centisome position: 62.56

GC content: 32.2

Gene sequence:

>354_bases
ATGAGTGAATATTTAACCATATTAATTTTTATCTGTGTATCAATTGTAGTATCCTTTACTTTAGGTGTATTACCTATGTT
TCTTGCAGTCAGTAACCCAGATGGTGAAAAGCTTTCTACATATGAGTGTGGCTTTAATCCTTTATCAAGAGCCAGAAAAA
GTTTCGACATAAAATTTTACTTAGTTGCAATATTGTTCATAATATTCGATTTAGAAATTGCTTTTCTTTTCCCTTGGGCC
GTTTCTTTATCTAAAATAAGCTATTGCGGATTTTGGTCTATGATGATATTCCTTGCAATACTTACTATAGGCTTTCTTTA
TGAGTGGTGTAAAGGTGCGTTGGAATGGGAATAA

Upstream 100 bases:

>100_bases
GTAAAGATGGAGAGCAAGTTATACCGCACTTTCACATACATATTTTAGGTGGTAAAAGATTAGGAAAGCATGTAAATTCA
TAGTGTTATATGTTTTTTAA

Downstream 100 bases:

>100_bases
ATTTATCTAATGGCGACTGGAATCGTTACAAAAAAGAAGGTTTTCTTATCACTAAATTTGGCGATTTAATAGATTATATA
ATGAACTGGGCAAGGTCTGG

Product: NADH dehydrogenase I, A subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A 1; NDH-1 subunit A 1; NUO1 1 [H]

Number of amino acids: Translated: 117; Mature: 116

Protein sequence:

>117_residues
MSEYLTILIFICVSIVVSFTLGVLPMFLAVSNPDGEKLSTYECGFNPLSRARKSFDIKFYLVAILFIIFDLEIAFLFPWA
VSLSKISYCGFWSMMIFLAILTIGFLYEWCKGALEWE

Sequences:

>Translated_117_residues
MSEYLTILIFICVSIVVSFTLGVLPMFLAVSNPDGEKLSTYECGFNPLSRARKSFDIKFYLVAILFIIFDLEIAFLFPWA
VSLSKISYCGFWSMMIFLAILTIGFLYEWCKGALEWE
>Mature_116_residues
SEYLTILIFICVSIVVSFTLGVLPMFLAVSNPDGEKLSTYECGFNPLSRARKSFDIKFYLVAILFIIFDLEIAFLFPWAV
SLSKISYCGFWSMMIFLAILTIGFLYEWCKGALEWE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=116, Percent_Identity=32.7586206896552, Blast_Score=62, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 13426; Mature: 13295

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEYLTILIFICVSIVVSFTLGVLPMFLAVSNPDGEKLSTYECGFNPLSRARKSFDIKFY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCHHHHHHHHCCHHHH
LVAILFIIFDLEIAFLFPWAVSLSKISYCGFWSMMIFLAILTIGFLYEWCKGALEWE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SEYLTILIFICVSIVVSFTLGVLPMFLAVSNPDGEKLSTYECGFNPLSRARKSFDIKFY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCHHHHHHHHCCHHHH
LVAILFIIFDLEIAFLFPWAVSLSKISYCGFWSMMIFLAILTIGFLYEWCKGALEWE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]