Click here to switch to the map view.

The map label for this gene is coaE [H]

Identifier: 190570586

GI number: 190570586

Start: 125864

End: 126442

Strand: Direct

Name: coaE [H]

Synonym: WPa_0121

Alternate gene names: 190570586

Gene position: 125864-126442 (Clockwise)

Preceding gene: 190570582

Following gene: 190570590

Centisome position: 8.49

GC content: 35.23

Gene sequence:

>579_bases
ATGATAATAGGTCTAACAGGTGGAATTGCAGTCGGAAAGAGCTTTGTAGCCAATTGCTTTAAAGAATTTGGTGCCGCTTT
GTTTGATGCTGACTCTGTCGTACACCAGCTTTATAAAGTGGACAAAAACATAATAAGTTATGCAGAAGAAAAATTTCCTG
GGGTAGTAGTAAATGGAAAAATTGATAGAACAGTATTGTCTAAATATTTTTTAGCACATGATGAAAATTGGAAGCAATTC
CAGTCTTTAGTACATTCCGCTGTGCAAAATGAATTAGAATTTTTTATTGCTCATGAGAAAGAAAACAACAGAAAACTTCT
AGTTCTAGACATTCCACTCCTGCTGGAAACGAGATTCCATTTGTATTGCGATTTTATTGTTTTTATCCATGCAGATAGCG
TTGTGCAAGCTCAAAGGATTAGTGAGCGTAATATGGATAAAAAAAAGCTGGATCTAATGTCTAGTATTCAGCTCCCTATT
GAAGAAAAAAAGCAAATGAGCGACTTTATCATCGATACCAGCGCAAATGTTCTTTCTCAAGTGAAAGATATAATAAACTC
GTTAGACCTCAACACGTGA

Upstream 100 bases:

>100_bases
TTGCTAAAAAAATAATAGCTTTTCTTTTAATGCACACAAATTCAGTTTTAAGTAGACATAACAGCTACGACACATATTCT
TTTTAAGAAGTCTTTGATAT

Downstream 100 bases:

>100_bases
TACGGTTATTCTCCACAAGATTACTCCGAATTTTAGCTGTACTATCAGCAGATTTTACCATTAAAATTTCAAACCTTGAG
CCTGCATTCAAAAACGATTC

Product: dephospho-coa kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MIIGLTGGIAVGKSFVANCFKEFGAALFDADSVVHQLYKVDKNIISYAEEKFPGVVVNGKIDRTVLSKYFLAHDENWKQF
QSLVHSAVQNELEFFIAHEKENNRKLLVLDIPLLLETRFHLYCDFIVFIHADSVVQAQRISERNMDKKKLDLMSSIQLPI
EEKKQMSDFIIDTSANVLSQVKDIINSLDLNT

Sequences:

>Translated_192_residues
MIIGLTGGIAVGKSFVANCFKEFGAALFDADSVVHQLYKVDKNIISYAEEKFPGVVVNGKIDRTVLSKYFLAHDENWKQF
QSLVHSAVQNELEFFIAHEKENNRKLLVLDIPLLLETRFHLYCDFIVFIHADSVVQAQRISERNMDKKKLDLMSSIQLPI
EEKKQMSDFIIDTSANVLSQVKDIINSLDLNT
>Mature_192_residues
MIIGLTGGIAVGKSFVANCFKEFGAALFDADSVVHQLYKVDKNIISYAEEKFPGVVVNGKIDRTVLSKYFLAHDENWKQF
QSLVHSAVQNELEFFIAHEKENNRKLLVLDIPLLLETRFHLYCDFIVFIHADSVVQAQRISERNMDKKKLDLMSSIQLPI
EEKKQMSDFIIDTSANVLSQVKDIINSLDLNT

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=187, Percent_Identity=29.9465240641711, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI191252795, Length=187, Percent_Identity=29.9465240641711, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17554944, Length=197, Percent_Identity=25.8883248730964, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320402, Length=186, Percent_Identity=26.3440860215054, Blast_Score=85, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24644728, Length=182, Percent_Identity=27.4725274725275, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21865; Mature: 21865

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIGLTGGIAVGKSFVANCFKEFGAALFDADSVVHQLYKVDKNIISYAEEKFPGVVVNGK
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
IDRTVLSKYFLAHDENWKQFQSLVHSAVQNELEFFIAHEKENNRKLLVLDIPLLLETRFH
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEEECHHHHHHHHH
LYCDFIVFIHADSVVQAQRISERNMDKKKLDLMSSIQLPIEEKKQMSDFIIDTSANVLSQ
HHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHH
VKDIINSLDLNT
HHHHHHHCCCCC
>Mature Secondary Structure
MIIGLTGGIAVGKSFVANCFKEFGAALFDADSVVHQLYKVDKNIISYAEEKFPGVVVNGK
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
IDRTVLSKYFLAHDENWKQFQSLVHSAVQNELEFFIAHEKENNRKLLVLDIPLLLETRFH
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEEECHHHHHHHHH
LYCDFIVFIHADSVVQAQRISERNMDKKKLDLMSSIQLPIEEKKQMSDFIIDTSANVLSQ
HHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHH
VKDIINSLDLNT
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA