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The map label for this gene is xerC [H]

Identifier: 190570559

GI number: 190570559

Start: 91819

End: 92739

Strand: Reverse

Name: xerC [H]

Synonym: WPa_0092

Alternate gene names: 190570559

Gene position: 92739-91819 (Counterclockwise)

Preceding gene: 190570560

Following gene: 190570558

Centisome position: 6.26

GC content: 34.42

Gene sequence:

>921_bases
GTGGACCTCGGTTCAATCATTGAAAAATGGTATGATTGGCTAAAGTACAACAGGTCTTACTCACCAAACACTTTGGAGTC
ATACATGAGGGACCTCAAGGATCTTATAAGTTTCCTAAATACTCACATTGGTGAAGAAGTAAATGTTGGCTCTTTAGAAA
AATTAAGCATACCTGAACTGAGAAGTTGGTTTACCTCTCGTTATGCAAGAGGTGTAAATGCGAGATCTAACACTCGCGCA
TTGTCAGTAATCAGAAATTTTTTCAAATATATAAAAAACAATTATGAAATAAATAATGAAGCGGTATTTTCTTTATCAAG
GCCAATTCAGAGAAGAACTCTACCTAAAGCACTTTCAATATCTAACATAGAAACTCTATTGAAAGAAATGAAATTGCCTG
ATCTAGGCGAGCCTTGGGTGGTAAAAAGAGAAATTGCAATTGTCGTTCTGCTATATGGTACGGGCTTAAGAATCACTGAA
GCACTGAATCTTAAGGTTAGTGATATTAGCAATGAAAGTTTAATAGTAACAGGTAAGGGAGATAAACAAAGGCAGGTATT
TATTCTTCCAGTAGTAAAAAAGTGTATACAAAAATATATAAAAGCTTGTCCCCACTTTGACGAAGCGGGACATCTTTTTG
TCGGGGTAAGAGGAAAAAAATTGGGAAGAACTTATGTTGCTAATCGTTTGCAAAAAATAAGAAGATTTTTAAACTTACCA
GAAATTTTATCTCCACATGCATTTCGCCATAGTTTTGCTACTCATTTGCTTCAGGAAGATATTGACATAAGATCAATACA
ACAGCTGCTTGGCCACTCAAGCCTTGAAACTACTCAAGTTTACACTCACCTAAATTATCAAGATGTCTTCAATATGTATA
AAAACTTTCAGAAGAGTTTGAATAAAAAATCGAAATCTTAA

Upstream 100 bases:

>100_bases
GTGCAGCAGCAGAGGATATATACAGAATTTGTCACTCTCATCCTGATATAAATGAAGCCTTTAGGGATGCGTGCATCGAT
GCTTTCTTTAAAAAGTAACT

Downstream 100 bases:

>100_bases
CTTCGTCTTAAATCGATAATATTGCCGAACTGAGTGCTTGCAACATCATTCAGTACTGTACTTGCTTTATATAAGCAATA
GTGACCAGCAGAGAAGAAAG

Product: site-specific recombinase, phage integrase family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MDLGSIIEKWYDWLKYNRSYSPNTLESYMRDLKDLISFLNTHIGEEVNVGSLEKLSIPELRSWFTSRYARGVNARSNTRA
LSVIRNFFKYIKNNYEINNEAVFSLSRPIQRRTLPKALSISNIETLLKEMKLPDLGEPWVVKREIAIVVLLYGTGLRITE
ALNLKVSDISNESLIVTGKGDKQRQVFILPVVKKCIQKYIKACPHFDEAGHLFVGVRGKKLGRTYVANRLQKIRRFLNLP
EILSPHAFRHSFATHLLQEDIDIRSIQQLLGHSSLETTQVYTHLNYQDVFNMYKNFQKSLNKKSKS

Sequences:

>Translated_306_residues
MDLGSIIEKWYDWLKYNRSYSPNTLESYMRDLKDLISFLNTHIGEEVNVGSLEKLSIPELRSWFTSRYARGVNARSNTRA
LSVIRNFFKYIKNNYEINNEAVFSLSRPIQRRTLPKALSISNIETLLKEMKLPDLGEPWVVKREIAIVVLLYGTGLRITE
ALNLKVSDISNESLIVTGKGDKQRQVFILPVVKKCIQKYIKACPHFDEAGHLFVGVRGKKLGRTYVANRLQKIRRFLNLP
EILSPHAFRHSFATHLLQEDIDIRSIQQLLGHSSLETTQVYTHLNYQDVFNMYKNFQKSLNKKSKS
>Mature_306_residues
MDLGSIIEKWYDWLKYNRSYSPNTLESYMRDLKDLISFLNTHIGEEVNVGSLEKLSIPELRSWFTSRYARGVNARSNTRA
LSVIRNFFKYIKNNYEINNEAVFSLSRPIQRRTLPKALSISNIETLLKEMKLPDLGEPWVVKREIAIVVLLYGTGLRITE
ALNLKVSDISNESLIVTGKGDKQRQVFILPVVKKCIQKYIKACPHFDEAGHLFVGVRGKKLGRTYVANRLQKIRRFLNLP
EILSPHAFRHSFATHLLQEDIDIRSIQQLLGHSSLETTQVYTHLNYQDVFNMYKNFQKSLNKKSKS

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=297, Percent_Identity=31.6498316498317, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789261, Length=296, Percent_Identity=31.4189189189189, Blast_Score=130, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35481; Mature: 35481

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGSIIEKWYDWLKYNRSYSPNTLESYMRDLKDLISFLNTHIGEEVNVGSLEKLSIPEL
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
RSWFTSRYARGVNARSNTRALSVIRNFFKYIKNNYEINNEAVFSLSRPIQRRTLPKALSI
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHCHHHHHH
SNIETLLKEMKLPDLGEPWVVKREIAIVVLLYGTGLRITEALNLKVSDISNESLIVTGKG
HHHHHHHHHCCCCCCCCCCEEEHHEEEEEEEECCCCEEEHHHCEEEECCCCCEEEEECCC
DKQRQVFILPVVKKCIQKYIKACPHFDEAGHLFVGVRGKKLGRTYVANRLQKIRRFLNLP
CCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCH
EILSPHAFRHSFATHLLQEDIDIRSIQQLLGHSSLETTQVYTHLNYQDVFNMYKNFQKSL
HHHCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHH
NKKSKS
HHCCCC
>Mature Secondary Structure
MDLGSIIEKWYDWLKYNRSYSPNTLESYMRDLKDLISFLNTHIGEEVNVGSLEKLSIPEL
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
RSWFTSRYARGVNARSNTRALSVIRNFFKYIKNNYEINNEAVFSLSRPIQRRTLPKALSI
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHCHHHHHH
SNIETLLKEMKLPDLGEPWVVKREIAIVVLLYGTGLRITEALNLKVSDISNESLIVTGKG
HHHHHHHHHCCCCCCCCCCEEEHHEEEEEEEECCCCEEEHHHCEEEECCCCCEEEEECCC
DKQRQVFILPVVKKCIQKYIKACPHFDEAGHLFVGVRGKKLGRTYVANRLQKIRRFLNLP
CCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCH
EILSPHAFRHSFATHLLQEDIDIRSIQQLLGHSSLETTQVYTHLNYQDVFNMYKNFQKSL
HHHCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHH
NKKSKS
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]