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The map label for this gene is engD [H]

Identifier: 190570539

GI number: 190570539

Start: 64043

End: 65137

Strand: Direct

Name: engD [H]

Synonym: WPa_0069

Alternate gene names: 190570539

Gene position: 64043-65137 (Clockwise)

Preceding gene: 190570537

Following gene: 190570542

Centisome position: 4.32

GC content: 36.71

Gene sequence:

>1095_bases
ATGAGCTTTAACTGTGGTATAGTTGGGTTACCAAATATAGGAAAATCAACTTTATTTAATGCACTTACAGAGTCAAGTGC
AGCTGAAGCTGCAAATTATCCTTTTTGCACAATCGAGCCAAATGTTGGCAAAGTGCCAATACGAGATCAGCGTTTGAAAC
AAATTGCCTCGATTGCTCACTCAGGGAAAATAATCTACAATCAACTGGAAGTTGTCGATATTGCCGGCTTGGTTAAGGGT
GCGAGCAAGGGTGAAGGACTAGGAAATAAATTTTTGAGTCATATCAGAGAAGTTGATGCCATTGTTCATCTGCTCAGGTG
CTTTACGGATGACGATATCAGCCATGTAAACAGTAAAATAGATCCAATATCAGATGCTGAAATAGTGGAAATGGAGTTAA
TTCTAGCTGATATTGATAGCATAGAAAAAAGGCTTCCTCAATTGGAAAAGAAAGCAAAGCAAGGTGATAAAGAGCTAAAG
AGACAACTTGAATTAATGCAAGAGGTATTAGCTACTTTAAAATTAGGTAAACCGGCAAGAAGCTTGGAGAATATCGATGA
AGATAAGATGAAGTTGCTTCAATTGCTAACAACAAAGCCTGTTATGTATGTATGCAATGTTGAAGATACGAATATCATAA
CTGGTAATGAACTATCTAAAAGGGTGGAAAAAATGGCGGAAGAAAACAAAAGCAAATTTTATTGTATTTCAGCGAAACTT
GAAGCAGATATTGCAAATCTTGATAGTGAAGAGGAAAAACAGAATTTTTTATTAGAATTTGGCTTACAAGAATCAGGACT
TGATGGAGTAGCACGTATTATGTATGAAGTGCTAAGTATGATAACTTTTTTTACTGTGGGCCCCAAAGAAGCACGTGCAT
GGCCAATAAAGATAGGATCAACAGCTGACAAAGCAGCAGGTGTAATTCACACTGATTTTGAAAAGGGCTTTATAAAAGCA
GAAACCATAAGCTTTGAAGACTATATAAAATATGGAAGCGAATTAGCTTGCAAAGATGCAGGGAAAATTCGCTTCGAAGG
CAGAGACTATATAGTGCAAGATGGTGATATAATGCACTTTAGGTTCAATGTGTAG

Upstream 100 bases:

>100_bases
AGCTATATGTTATTATATTAACTAACTTATTAATAAGTAACTAATTAGGTATAGCAAAAATTTTTTAATTATGCAATAAT
TAAGGCTTTAAATAGCAAAT

Downstream 100 bases:

>100_bases
TATACATCTAACTCCCAAAGAACCAGGGAATCGAGCCTTTCTTTATGGCTTCCTCTTCGCTGATCCCTGTGGTTGTATAT
TCTTCTCTTCCTCACATAAT

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MSFNCGIVGLPNIGKSTLFNALTESSAAEAANYPFCTIEPNVGKVPIRDQRLKQIASIAHSGKIIYNQLEVVDIAGLVKG
ASKGEGLGNKFLSHIREVDAIVHLLRCFTDDDISHVNSKIDPISDAEIVEMELILADIDSIEKRLPQLEKKAKQGDKELK
RQLELMQEVLATLKLGKPARSLENIDEDKMKLLQLLTTKPVMYVCNVEDTNIITGNELSKRVEKMAEENKSKFYCISAKL
EADIANLDSEEEKQNFLLEFGLQESGLDGVARIMYEVLSMITFFTVGPKEARAWPIKIGSTADKAAGVIHTDFEKGFIKA
ETISFEDYIKYGSELACKDAGKIRFEGRDYIVQDGDIMHFRFNV

Sequences:

>Translated_364_residues
MSFNCGIVGLPNIGKSTLFNALTESSAAEAANYPFCTIEPNVGKVPIRDQRLKQIASIAHSGKIIYNQLEVVDIAGLVKG
ASKGEGLGNKFLSHIREVDAIVHLLRCFTDDDISHVNSKIDPISDAEIVEMELILADIDSIEKRLPQLEKKAKQGDKELK
RQLELMQEVLATLKLGKPARSLENIDEDKMKLLQLLTTKPVMYVCNVEDTNIITGNELSKRVEKMAEENKSKFYCISAKL
EADIANLDSEEEKQNFLLEFGLQESGLDGVARIMYEVLSMITFFTVGPKEARAWPIKIGSTADKAAGVIHTDFEKGFIKA
ETISFEDYIKYGSELACKDAGKIRFEGRDYIVQDGDIMHFRFNV
>Mature_363_residues
SFNCGIVGLPNIGKSTLFNALTESSAAEAANYPFCTIEPNVGKVPIRDQRLKQIASIAHSGKIIYNQLEVVDIAGLVKGA
SKGEGLGNKFLSHIREVDAIVHLLRCFTDDDISHVNSKIDPISDAEIVEMELILADIDSIEKRLPQLEKKAKQGDKELKR
QLELMQEVLATLKLGKPARSLENIDEDKMKLLQLLTTKPVMYVCNVEDTNIITGNELSKRVEKMAEENKSKFYCISAKLE
ADIANLDSEEEKQNFLLEFGLQESGLDGVARIMYEVLSMITFFTVGPKEARAWPIKIGSTADKAAGVIHTDFEKGFIKAE
TISFEDYIKYGSELACKDAGKIRFEGRDYIVQDGDIMHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=371, Percent_Identity=44.2048517520216, Blast_Score=286, Evalue=2e-77,
Organism=Homo sapiens, GI58761502, Length=226, Percent_Identity=38.4955752212389, Blast_Score=139, Evalue=3e-33,
Organism=Escherichia coli, GI1787454, Length=366, Percent_Identity=51.9125683060109, Blast_Score=378, Evalue=1e-106,
Organism=Escherichia coli, GI1789574, Length=130, Percent_Identity=31.5384615384615, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17509631, Length=368, Percent_Identity=41.304347826087, Blast_Score=274, Evalue=5e-74,
Organism=Caenorhabditis elegans, GI17552324, Length=104, Percent_Identity=32.6923076923077, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319499, Length=375, Percent_Identity=38.4, Blast_Score=237, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6321773, Length=379, Percent_Identity=35.8839050131926, Blast_Score=211, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6321649, Length=157, Percent_Identity=35.6687898089172, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24640873, Length=370, Percent_Identity=42.7027027027027, Blast_Score=276, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24640877, Length=370, Percent_Identity=42.7027027027027, Blast_Score=276, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24640875, Length=370, Percent_Identity=42.7027027027027, Blast_Score=276, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24640879, Length=328, Percent_Identity=40.2439024390244, Blast_Score=221, Evalue=5e-58,
Organism=Drosophila melanogaster, GI24585318, Length=170, Percent_Identity=31.1764705882353, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40573; Mature: 40442

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFNCGIVGLPNIGKSTLFNALTESSAAEAANYPFCTIEPNVGKVPIRDQRLKQIASIAH
CCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHH
SGKIIYNQLEVVDIAGLVKGASKGEGLGNKFLSHIREVDAIVHLLRCFTDDDISHVNSKI
CCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCC
DPISDAEIVEMELILADIDSIEKRLPQLEKKAKQGDKELKRQLELMQEVLATLKLGKPAR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHH
SLENIDEDKMKLLQLLTTKPVMYVCNVEDTNIITGNELSKRVEKMAEENKSKFYCISAKL
HHHCCCHHHHHHHHHHHCCCEEEEEECCCCCEECCHHHHHHHHHHHHCCCCEEEEEEEEE
EADIANLDSEEEKQNFLLEFGLQESGLDGVARIMYEVLSMITFFTVGPKEARAWPIKIGS
HHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECC
TADKAAGVIHTDFEKGFIKAETISFEDYIKYGSELACKDAGKIRFEGRDYIVQDGDIMHF
CCHHHCCCEEECCCCCCEEEEEECHHHHHHCCCCEEECCCCCEEECCCEEEEECCCEEEE
RFNV
EECC
>Mature Secondary Structure 
SFNCGIVGLPNIGKSTLFNALTESSAAEAANYPFCTIEPNVGKVPIRDQRLKQIASIAH
CCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHH
SGKIIYNQLEVVDIAGLVKGASKGEGLGNKFLSHIREVDAIVHLLRCFTDDDISHVNSKI
CCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCC
DPISDAEIVEMELILADIDSIEKRLPQLEKKAKQGDKELKRQLELMQEVLATLKLGKPAR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHH
SLENIDEDKMKLLQLLTTKPVMYVCNVEDTNIITGNELSKRVEKMAEENKSKFYCISAKL
HHHCCCHHHHHHHHHHHCCCEEEEEECCCCCEECCHHHHHHHHHHHHCCCCEEEEEEEEE
EADIANLDSEEEKQNFLLEFGLQESGLDGVARIMYEVLSMITFFTVGPKEARAWPIKIGS
HHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECC
TADKAAGVIHTDFEKGFIKAETISFEDYIKYGSELACKDAGKIRFEGRDYIVQDGDIMHF
CCHHHCCCEEECCCCCCEEEEEECHHHHHHCCCCEEECCCCCEEECCCEEEEECCCEEEE
RFNV
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA