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The map label for this gene is ppcA

Identifier: 18978347

GI number: 18978347

Start: 1825412

End: 1826830

Strand: Direct

Name: ppcA

Synonym: PF1975

Alternate gene names: 18978347

Gene position: 1825412-1826830 (Clockwise)

Preceding gene: 18978346

Following gene: 18978348

Centisome position: 95.66

GC content: 40.31

Gene sequence:

>1419_bases
ATGATACCAAGAATAATGAGTACTCAACATCCTGACAACTATTCAATACCATTTTTCGCTAGCTCCCCCATACTAGAGGG
AGAAGATGAGATAACGGAGGCATTCTATGCCTTCAGTGTCCTTGGAGCAGATGAACAAATGTGGGACTTTGAAGGAAAAG
AAGTTGATGAATTCGTTGTTAAAAAACTTCTCGAGAGATACCCAACATTTTTCAAGAACAATATTCTTGGAAAGGATATT
CGCCTGACCCCAAGAGTTCCAAACCCAAGTGTAGAAAAAGAAGAAGCAAAGTTACTTCTCGAAACCCTTCAAGGAATCGC
AAGAAGTGCGGATTATGCAAGGATATTCTATGGAGATAACATAGCTCCAATATTCGAAGTAATACTTCCCATGACAACTA
GTGTAGAGGAAATTGAGAGAGTATACTGGCTCTATAAGAAGGCAGTAGTTTGGATAAGCAGAGAGAAAATCTATGATATA
ACAGTAAGGGAGTGGATCGGAGATTTCTTCCCAGAAAAAATTAATGTAATCCCACTGTTTGAGACGAAATCCGCTCTAAT
CAAAGCTGCAAAAATAACAGAAGCTTACATACTAAATAGGAAGAATGACATTGAGTATCAGAGGGTCTTTTTTGCTAGAA
GTGATCCCGCAATGAACTACGGTCTAATTACAGCAGTCACTTACGTTAAAAGGGCACTATATGAAGTTCTAAAGGTAGAA
GAGGAGCTCAGCATTCCAATATACCCAATTATCGGAGTTGGTGGTCCTCCCTTGAGAGGAGGAATGAGACCAGATAACGT
TGATGCAGTAGTAAAGGAATATCCAAGTGTCCAAACCTTCACAATCCAGAGCTCCTTCAAGTATGACTACCCAACCAAAG
ACGTCGTTAAGGCGGTAGAGAAAATTAAATCGACAAAAAGAAAGTTGCCAATTCCAGTTGAAATTCCTCCATTTCTGGTT
AACTATGAGGCAGAATACCAAAAGCAGATTAGAATTCTAGCCCCATACATAAACAGCGTAGCAAAGAGAATACCCAGGAG
AAGAAAGAGGAAGCTCCACATAGGATTATTCGGATATTCAAGAAATGTGAACGGGATAACTCTGCCCAGAGCAATCACAT
TCACTGCTGCCCTTTACTCCATCGGAATCCCCCCAGAACTTCTTGCATTAAACTCACTCACAGACTCCCAACTCGAAACA
ATTTCAGAATACTACATCAACGTATATGAAGACTTAGAATTTGCCATGAGATTTTTCTCTCCAAAAGTTGCTGAAAAGGT
AGGATTGAAAGAGCTAGCAGAAAGGGTCAAGGAATTCAAACCAGAGCAAATCCCTGAGTACATTGAGGAGGCAGAAATAG
TGTTTAAAGGGGAAGGAGATGTGATGAAGCTGGCCCAGTTAAGAGGGTTTCTTGGATAA

Upstream 100 bases:

>100_bases
AGGAGCATTAACTTCTAGAATCTTAAATTCTTCGTCTTTTGTTTAAAACTTCTTCCAATATCTTTAAATATGACTAATTA
GCTCGATCTTGGAGGGCATT

Downstream 100 bases:

>100_bases
AGCCCATATACCTCTACACTTTTTTCTCTGAGAGGGAGAGGAAAAATGAAGGTGGCAGTAGTTGGGAGTGGCCTCGCAGG
TTTAACCGCTGCAATGTCAT

Product: phosphoenolpyruvate carboxylase

Products: NA

Alternate protein names: PEPC; PEPCase

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MIPRIMSTQHPDNYSIPFFASSPILEGEDEITEAFYAFSVLGADEQMWDFEGKEVDEFVVKKLLERYPTFFKNNILGKDI
RLTPRVPNPSVEKEEAKLLLETLQGIARSADYARIFYGDNIAPIFEVILPMTTSVEEIERVYWLYKKAVVWISREKIYDI
TVREWIGDFFPEKINVIPLFETKSALIKAAKITEAYILNRKNDIEYQRVFFARSDPAMNYGLITAVTYVKRALYEVLKVE
EELSIPIYPIIGVGGPPLRGGMRPDNVDAVVKEYPSVQTFTIQSSFKYDYPTKDVVKAVEKIKSTKRKLPIPVEIPPFLV
NYEAEYQKQIRILAPYINSVAKRIPRRRKRKLHIGLFGYSRNVNGITLPRAITFTAALYSIGIPPELLALNSLTDSQLET
ISEYYINVYEDLEFAMRFFSPKVAEKVGLKELAERVKEFKPEQIPEYIEEAEIVFKGEGDVMKLAQLRGFLG

Sequences:

>Translated_472_residues
MIPRIMSTQHPDNYSIPFFASSPILEGEDEITEAFYAFSVLGADEQMWDFEGKEVDEFVVKKLLERYPTFFKNNILGKDI
RLTPRVPNPSVEKEEAKLLLETLQGIARSADYARIFYGDNIAPIFEVILPMTTSVEEIERVYWLYKKAVVWISREKIYDI
TVREWIGDFFPEKINVIPLFETKSALIKAAKITEAYILNRKNDIEYQRVFFARSDPAMNYGLITAVTYVKRALYEVLKVE
EELSIPIYPIIGVGGPPLRGGMRPDNVDAVVKEYPSVQTFTIQSSFKYDYPTKDVVKAVEKIKSTKRKLPIPVEIPPFLV
NYEAEYQKQIRILAPYINSVAKRIPRRRKRKLHIGLFGYSRNVNGITLPRAITFTAALYSIGIPPELLALNSLTDSQLET
ISEYYINVYEDLEFAMRFFSPKVAEKVGLKELAERVKEFKPEQIPEYIEEAEIVFKGEGDVMKLAQLRGFLG
>Mature_472_residues
MIPRIMSTQHPDNYSIPFFASSPILEGEDEITEAFYAFSVLGADEQMWDFEGKEVDEFVVKKLLERYPTFFKNNILGKDI
RLTPRVPNPSVEKEEAKLLLETLQGIARSADYARIFYGDNIAPIFEVILPMTTSVEEIERVYWLYKKAVVWISREKIYDI
TVREWIGDFFPEKINVIPLFETKSALIKAAKITEAYILNRKNDIEYQRVFFARSDPAMNYGLITAVTYVKRALYEVLKVE
EELSIPIYPIIGVGGPPLRGGMRPDNVDAVVKEYPSVQTFTIQSSFKYDYPTKDVVKAVEKIKSTKRKLPIPVEIPPFLV
NYEAEYQKQIRILAPYINSVAKRIPRRRKRKLHIGLFGYSRNVNGITLPRAITFTAALYSIGIPPELLALNSLTDSQLET
ISEYYINVYEDLEFAMRFFSPKVAEKVGLKELAERVKEFKPEQIPEYIEEAEIVFKGEGDVMKLAQLRGFLG

Specific function: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle

COG id: COG1892

COG function: function code S; Uncharacterized protein conserved in archaea

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEPCase type 2 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CAPPA_PYRFU (Q8TZL5)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_579704.1
- ProteinModelPortal:   Q8TZL5
- EnsemblBacteria:   EBPYRT00000004942
- GeneID:   1469857
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF1975
- NMPDR:   fig|186497.1.peg.2027
- GeneTree:   EBGT00050000022392
- HOGENOM:   HBG392160
- OMA:   MCTQHPD
- ProtClustDB:   PRK13655
- BRENDA:   4.1.1.31
- HAMAP:   MF_01904
- InterPro:   IPR021135
- InterPro:   IPR007566
- InterPro:   IPR015813
- PIRSF:   PIRSF006677
- TIGRFAMs:   TIGR02751

Pfam domain/function: PF00311 PEPcase; SSF51621 Pyrv/PenolPyrv_Kinase_cat

EC number: =4.1.1.31

Molecular weight: Translated: 54316; Mature: 54316

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPRIMSTQHPDNYSIPFFASSPILEGEDEITEAFYAFSVLGADEQMWDFEGKEVDEFVV
CCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHH
KKLLERYPTFFKNNILGKDIRLTPRVPNPSVEKEEAKLLLETLQGIARSADYARIFYGDN
HHHHHHCCHHHHCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCC
IAPIFEVILPMTTSVEEIERVYWLYKKAVVWISREKIYDITVREWIGDFFPEKINVIPLF
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEECCCEEEHHHHHHHHHHCCCCEEEEEEE
ETKSALIKAAKITEAYILNRKNDIEYQRVFFARSDPAMNYGLITAVTYVKRALYEVLKVE
CCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
EELSIPIYPIIGVGGPPLRGGMRPDNVDAVVKEYPSVQTFTIQSSFKYDYPTKDVVKAVE
HHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHH
KIKSTKRKLPIPVEIPPFLVNYEAEYQKQIRILAPYINSVAKRIPRRRKRKLHIGLFGYS
HHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEC
RNVNGITLPRAITFTAALYSIGIPPELLALNSLTDSQLETISEYYINVYEDLEFAMRFFS
CCCCCEECCHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
PKVAEKVGLKELAERVKEFKPEQIPEYIEEAEIVFKGEGDVMKLAQLRGFLG
HHHHHHCCHHHHHHHHHHCCHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure
MIPRIMSTQHPDNYSIPFFASSPILEGEDEITEAFYAFSVLGADEQMWDFEGKEVDEFVV
CCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHH
KKLLERYPTFFKNNILGKDIRLTPRVPNPSVEKEEAKLLLETLQGIARSADYARIFYGDN
HHHHHHCCHHHHCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCC
IAPIFEVILPMTTSVEEIERVYWLYKKAVVWISREKIYDITVREWIGDFFPEKINVIPLF
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEECCCEEEHHHHHHHHHHCCCCEEEEEEE
ETKSALIKAAKITEAYILNRKNDIEYQRVFFARSDPAMNYGLITAVTYVKRALYEVLKVE
CCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
EELSIPIYPIIGVGGPPLRGGMRPDNVDAVVKEYPSVQTFTIQSSFKYDYPTKDVVKAVE
HHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHH
KIKSTKRKLPIPVEIPPFLVNYEAEYQKQIRILAPYINSVAKRIPRRRKRKLHIGLFGYS
HHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEC
RNVNGITLPRAITFTAALYSIGIPPELLALNSLTDSQLETISEYYINVYEDLEFAMRFFS
CCCCCEECCHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
PKVAEKVGLKELAERVKEFKPEQIPEYIEEAEIVFKGEGDVMKLAQLRGFLG
HHHHHHCCHHHHHHHHHHCCHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA