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The map label for this gene is nrdD [C]

Identifier: 18978343

GI number: 18978343

Start: 1820217

End: 1822034

Strand: Direct

Name: nrdD [C]

Synonym: PF1971

Alternate gene names: 18978343

Gene position: 1820217-1822034 (Clockwise)

Preceding gene: 18978342

Following gene: 18978344

Centisome position: 95.39

GC content: 43.4

Gene sequence:

>1818_bases
ATGGAAAAGGTGGACATCATCCACGAGTATGCAAGGTGGGGAAGTCTTGACGTTCTGGAGAACGCAAATAGATACCCAGG
ACCTAGTGGATTCTTTGCCTATGTAATGGAAGAAGCACTAAAAAGTAGCTTAAGCTTAATTCCAGAGGTCGGATTAAGGG
CTCACTTCTCAGGAGATATTTACATCCACAAGCTCCCCTACAGTCTCTACATACCTTATTGTACAGGGCACAGCATTGCT
AGATTACTAAAGAGAGGGTTGAGGACGCCAACAATAACTTCTAGACCAGCTAAACACTTCGACACCTTCGTTGATCACAT
TGCAAACTACCTAATAACCCTACAACACTACTTCTCTGGTGCACAGGCTTTCTCAAGCGTTGAATGGTATGCTGGACCAT
TCATAAGGAAGGAAAATCTAGATCTAAGAAAAGTAAAGCAAAATATTCAAAGGTTAGTCTATAACCTAAATTACCCAACA
AGAATTGGCCTTCAGACCCCCTTTACGAACTTTACGGTAACTCTCGATGCTCCAAAGAAAATGCTTGAAGGAGATTACGC
AATATACAATGGAGAAGAAGTAGCTCCTCTAGGTGAATATGAGAGAGAGGCTAAGATGTTCATATTGGCTCTTACCGAGG
TTCTCAGAGAAGGAGATGCCCTAGGACAGCCTTTCACGTTTCCAATCCCCACCCTTATGGTAACCGCGGATATGATTTGG
AATGACCCCGAAGTTTTTGAAGCTATCTTTACCACAGCTGCTAAACGAGGAAGCTTCTACTGGTTGAACACCAACGTTGT
TGATCCAGATGCAAGCTATGCAATGTGCTGTAGGTTAAACATAGATAAGAGAGAATTCACATATACATTCTCGCTAGATG
AAGATGTAGAGAAGCTCGAAAGGCAAAGATTTGGTGGATTATGGGCAATGCCCGATGTTACTGGTTCTGTAAACGTTACA
ACAGTTAACCTTCCCAGGATTGCCCTCAAAAGCAGAGATGAAGATGAGTTCTGGGAAGAATACGAAAAGACCCTCGAGAT
AGTTAGGATAACAACCGAATGGTTCAGAAACAGGTATGTTAAGTTGCTCTCCATGTATCCCCACATGTACAGCATGATAA
GGGACTACTTAGAGGAATTTCCATCAAGCCACTTCAACACCATCGGAATCCTGGGACTTCCAGAAGCTGCCGCATTATAC
CTAAACTCCCCAGAGTTGTGGAAAGAAGGAAATAGAAGGGATTGGATCGAGGCTGCAAGGTTAATGAAGAGAATGGTGGA
GTTTGCTACAGAAAAGGCCAGAGAATGGATGAAAGCTACAAGAGTTCCATGGAATGTTGAAGAAGTTCCTGGGGAAAGCG
CACAAGCTAAGTTAGCTCTCAAAGATATGAAGGACTTTCCAGAGTTAAAGGAATACCTAGATGACCCCGAGAATCCTATC
TACTCAACTAGCATAGCCCCCTACTACGGCCCACTTGAACTAGGAGACAGGATTAGAATTGAGGAAATCGTCCAAGGAAG
CTTCACGGGAGGGGTAATGATGCATATCTTCCTGGGAGAAGAGCCAGATCCTGAGGCATTAGCTGAGCTAACTAAAAAGC
TAATGAAGACCAAGCTAGTATACTGGAGTTACACTCCAGCTTTAACGGTCTGCAACTCGTGTAAATCCTCCTTCACAGGA
TTATATACGAGTTGCCCCAAGTGTGGAAGCCACGATGTAGAGGTATGGAGTAGAATAATAGGCTATTATAGGCCATTGAA
GAACTGGAATCCATATAGGAAGAAAGAGTTCTGGAGAAGGAAACACTACTTAGCCTGA

Upstream 100 bases:

>100_bases
TATGGATATTTTAGCCAAATGCTAATTTTCTTTCCACAACCCATAAAAGCTACATATTTCCCAGGGTATGATTGGACAAA
ATATCCAAAGGGGTGAAAGC

Downstream 100 bases:

>100_bases
GGTGTCTCTATGCTTATCGGAGGATGGAAGGCAGTAAGCATGGTAGACATTCCTGGGAAGGTTACCTTTACCCTCTGGCT
TTGCGGATGCAATCTTAGAT

Product: anaerobic ribonucleoside triphosphate reductase

Products: ribonucleoside triphosphate; thioredoxin

Alternate protein names: NA

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MEKVDIIHEYARWGSLDVLENANRYPGPSGFFAYVMEEALKSSLSLIPEVGLRAHFSGDIYIHKLPYSLYIPYCTGHSIA
RLLKRGLRTPTITSRPAKHFDTFVDHIANYLITLQHYFSGAQAFSSVEWYAGPFIRKENLDLRKVKQNIQRLVYNLNYPT
RIGLQTPFTNFTVTLDAPKKMLEGDYAIYNGEEVAPLGEYEREAKMFILALTEVLREGDALGQPFTFPIPTLMVTADMIW
NDPEVFEAIFTTAAKRGSFYWLNTNVVDPDASYAMCCRLNIDKREFTYTFSLDEDVEKLERQRFGGLWAMPDVTGSVNVT
TVNLPRIALKSRDEDEFWEEYEKTLEIVRITTEWFRNRYVKLLSMYPHMYSMIRDYLEEFPSSHFNTIGILGLPEAAALY
LNSPELWKEGNRRDWIEAARLMKRMVEFATEKAREWMKATRVPWNVEEVPGESAQAKLALKDMKDFPELKEYLDDPENPI
YSTSIAPYYGPLELGDRIRIEEIVQGSFTGGVMMHIFLGEEPDPEALAELTKKLMKTKLVYWSYTPALTVCNSCKSSFTG
LYTSCPKCGSHDVEVWSRIIGYYRPLKNWNPYRKKEFWRRKHYLA

Sequences:

>Translated_605_residues
MEKVDIIHEYARWGSLDVLENANRYPGPSGFFAYVMEEALKSSLSLIPEVGLRAHFSGDIYIHKLPYSLYIPYCTGHSIA
RLLKRGLRTPTITSRPAKHFDTFVDHIANYLITLQHYFSGAQAFSSVEWYAGPFIRKENLDLRKVKQNIQRLVYNLNYPT
RIGLQTPFTNFTVTLDAPKKMLEGDYAIYNGEEVAPLGEYEREAKMFILALTEVLREGDALGQPFTFPIPTLMVTADMIW
NDPEVFEAIFTTAAKRGSFYWLNTNVVDPDASYAMCCRLNIDKREFTYTFSLDEDVEKLERQRFGGLWAMPDVTGSVNVT
TVNLPRIALKSRDEDEFWEEYEKTLEIVRITTEWFRNRYVKLLSMYPHMYSMIRDYLEEFPSSHFNTIGILGLPEAAALY
LNSPELWKEGNRRDWIEAARLMKRMVEFATEKAREWMKATRVPWNVEEVPGESAQAKLALKDMKDFPELKEYLDDPENPI
YSTSIAPYYGPLELGDRIRIEEIVQGSFTGGVMMHIFLGEEPDPEALAELTKKLMKTKLVYWSYTPALTVCNSCKSSFTG
LYTSCPKCGSHDVEVWSRIIGYYRPLKNWNPYRKKEFWRRKHYLA
>Mature_605_residues
MEKVDIIHEYARWGSLDVLENANRYPGPSGFFAYVMEEALKSSLSLIPEVGLRAHFSGDIYIHKLPYSLYIPYCTGHSIA
RLLKRGLRTPTITSRPAKHFDTFVDHIANYLITLQHYFSGAQAFSSVEWYAGPFIRKENLDLRKVKQNIQRLVYNLNYPT
RIGLQTPFTNFTVTLDAPKKMLEGDYAIYNGEEVAPLGEYEREAKMFILALTEVLREGDALGQPFTFPIPTLMVTADMIW
NDPEVFEAIFTTAAKRGSFYWLNTNVVDPDASYAMCCRLNIDKREFTYTFSLDEDVEKLERQRFGGLWAMPDVTGSVNVT
TVNLPRIALKSRDEDEFWEEYEKTLEIVRITTEWFRNRYVKLLSMYPHMYSMIRDYLEEFPSSHFNTIGILGLPEAAALY
LNSPELWKEGNRRDWIEAARLMKRMVEFATEKAREWMKATRVPWNVEEVPGESAQAKLALKDMKDFPELKEYLDDPENPI
YSTSIAPYYGPLELGDRIRIEEIVQGSFTGGVMMHIFLGEEPDPEALAELTKKLMKTKLVYWSYTPALTVCNSCKSSFTG
LYTSCPKCGSHDVEVWSRIIGYYRPLKNWNPYRKKEFWRRKHYLA

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DOD-type homing endonuclease domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003586
- InterPro:   IPR003587
- InterPro:   IPR007869
- InterPro:   IPR006142
- InterPro:   IPR004042
- InterPro:   IPR006141
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF05204 Hom_end [H]

EC number: 1.17.4.2

Molecular weight: Translated: 70176; Mature: 70176

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKVDIIHEYARWGSLDVLENANRYPGPSGFFAYVMEEALKSSLSLIPEVGLRAHFSGDI
CCHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCE
YIHKLPYSLYIPYCTGHSIARLLKRGLRTPTITSRPAKHFDTFVDHIANYLITLQHYFSG
EEEECCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AQAFSSVEWYAGPFIRKENLDLRKVKQNIQRLVYNLNYPTRIGLQTPFTNFTVTLDAPKK
HHHHHCCHHHCCCCEECCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEECCCHH
MLEGDYAIYNGEEVAPLGEYEREAKMFILALTEVLREGDALGQPFTFPIPTLMVTADMIW
HHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHC
NDPEVFEAIFTTAAKRGSFYWLNTNVVDPDASYAMCCRLNIDKREFTYTFSLDEDVEKLE
CCHHHHHHHHHHHHCCCCEEEEECCEECCCCCEEEEEEECCCCCEEEEEEECCHHHHHHH
RQRFGGLWAMPDVTGSVNVTTVNLPRIALKSRDEDEFWEEYEKTLEIVRITTEWFRNRYV
HHHHCCEEECCCCCCCEEEEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KLLSMYPHMYSMIRDYLEEFPSSHFNTIGILGLPEAAALYLNSPELWKEGNRRDWIEAAR
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHEEEECCHHHHHCCCCCHHHHHHH
LMKRMVEFATEKAREWMKATRVPWNVEEVPGESAQAKLALKDMKDFPELKEYLDDPENPI
HHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCE
YSTSIAPYYGPLELGDRIRIEEIVQGSFTGGVMMHIFLGEEPDPEALAELTKKLMKTKLV
EECCCCCCCCCCCCCCCCCHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHEE
YWSYTPALTVCNSCKSSFTGLYTSCPKCGSHDVEVWSRIIGYYRPLKNWNPYRKKEFWRR
EEECCHHHHHHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
KHYLA
HCCCC
>Mature Secondary Structure
MEKVDIIHEYARWGSLDVLENANRYPGPSGFFAYVMEEALKSSLSLIPEVGLRAHFSGDI
CCHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCE
YIHKLPYSLYIPYCTGHSIARLLKRGLRTPTITSRPAKHFDTFVDHIANYLITLQHYFSG
EEEECCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AQAFSSVEWYAGPFIRKENLDLRKVKQNIQRLVYNLNYPTRIGLQTPFTNFTVTLDAPKK
HHHHHCCHHHCCCCEECCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEECCCHH
MLEGDYAIYNGEEVAPLGEYEREAKMFILALTEVLREGDALGQPFTFPIPTLMVTADMIW
HHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHC
NDPEVFEAIFTTAAKRGSFYWLNTNVVDPDASYAMCCRLNIDKREFTYTFSLDEDVEKLE
CCHHHHHHHHHHHHCCCCEEEEECCEECCCCCEEEEEEECCCCCEEEEEEECCHHHHHHH
RQRFGGLWAMPDVTGSVNVTTVNLPRIALKSRDEDEFWEEYEKTLEIVRITTEWFRNRYV
HHHHCCEEECCCCCCCEEEEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KLLSMYPHMYSMIRDYLEEFPSSHFNTIGILGLPEAAALYLNSPELWKEGNRRDWIEAAR
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHEEEECCHHHHHCCCCCHHHHHHH
LMKRMVEFATEKAREWMKATRVPWNVEEVPGESAQAKLALKDMKDFPELKEYLDDPENPI
HHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCE
YSTSIAPYYGPLELGDRIRIEEIVQGSFTGGVMMHIFLGEEPDPEALAELTKKLMKTKLV
EECCCCCCCCCCCCCCCCCHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHEE
YWSYTPALTVCNSCKSSFTGLYTSCPKCGSHDVEVWSRIIGYYRPLKNWNPYRKKEFWRR
EEECCHHHHHHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
KHYLA
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Ca2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2'-deoxyribonucleoside triphosphate; thioredoxin disulfide; H2O

Specific reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]