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The map label for this gene is yqjC [H]

Identifier: 18978320

GI number: 18978320

Start: 1800588

End: 1800989

Strand: Direct

Name: yqjC [H]

Synonym: PF1948

Alternate gene names: 18978320

Gene position: 1800588-1800989 (Clockwise)

Preceding gene: 18978319

Following gene: 18978325

Centisome position: 94.36

GC content: 41.79

Gene sequence:

>402_bases
GTGTTTAAGAAAATTGACCACGTTGGAATAGCTGTGAAGAATTTAGAAGAAGCCATTAAGATTTGGGAAGGGCTAGGACT
AAAAGTTGAGGAAATAGAAGAAGTTCCTGACCAGAAAGTTAGAGTCGCCGTTATAAAGATTGGAGAGAGCAGAATTGAGC
TTTTAGAGGCAACCAGCGAAGATTCTCCTATTGCAAAGTTTATTGAGAAGAGAGGAGAGGGAATACACCACATAGCTCTT
GGGGTTGAAGGAATTGAGAAGAAGCTCGAGGAGCTCAAAGAGAAGGGGTACAGGTTAATAGATGAAAAACCAAGAATAGG
AGCAGGAGGAGCTAAGATAGCCTTCATTCATCCAAAGAGCGTAACGGGAGTTCTTCTTGAGTTATGCGAAAGGAAGGAAT
GA

Upstream 100 bases:

>100_bases
GGAAATCTTGAAGATATTTTAGAGAAGGTTATGAAAAAGGAACTAGATCCTTACTCTGCCGCTTCCCTTATCATGGAAAA
AATAATTGGAGGTGGGAAGA

Downstream 100 bases:

>100_bases
TTACTTCTCCTCTCTTTTTATATATGGCTTTCCTATAGCTATTGTGAAGTCTTTGAATGAATCATCTTTTCTATGGAACT
CAATTGCTAATGGTAGATCA

Product: hypothetical protein

Products: glutathione; methylglyoxal

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MFKKIDHVGIAVKNLEEAIKIWEGLGLKVEEIEEVPDQKVRVAVIKIGESRIELLEATSEDSPIAKFIEKRGEGIHHIAL
GVEGIEKKLEELKEKGYRLIDEKPRIGAGGAKIAFIHPKSVTGVLLELCERKE

Sequences:

>Translated_133_residues
MFKKIDHVGIAVKNLEEAIKIWEGLGLKVEEIEEVPDQKVRVAVIKIGESRIELLEATSEDSPIAKFIEKRGEGIHHIAL
GVEGIEKKLEELKEKGYRLIDEKPRIGAGGAKIAFIHPKSVTGVLLELCERKE
>Mature_133_residues
MFKKIDHVGIAVKNLEEAIKIWEGLGLKVEEIEEVPDQKVRVAVIKIGESRIELLEATSEDSPIAKFIEKRGEGIHHIAL
GVEGIEKKLEELKEKGYRLIDEKPRIGAGGAKIAFIHPKSVTGVLLELCERKE

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyoxalase I family [H]

Homologues:

Organism=Homo sapiens, GI188035928, Length=127, Percent_Identity=39.3700787401575, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17506387, Length=129, Percent_Identity=39.5348837209302, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360
- InterPro:   IPR018146
- InterPro:   IPR017515 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 14845; Mature: 14845

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKIDHVGIAVKNLEEAIKIWEGLGLKVEEIEEVPDQKVRVAVIKIGESRIELLEATSE
CCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCEEEEEEEECHHHHHHHHHCCC
DSPIAKFIEKRGEGIHHIALGVEGIEKKLEELKEKGYRLIDEKPRIGAGGAKIAFIHPKS
CCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCEEEEECCCH
VTGVLLELCERKE
HHHHHHHHHHCCC
>Mature Secondary Structure
MFKKIDHVGIAVKNLEEAIKIWEGLGLKVEEIEEVPDQKVRVAVIKIGESRIELLEATSE
CCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCEEEEEEEECHHHHHHHHHCCC
DSPIAKFIEKRGEGIHHIALGVEGIEKKLEELKEKGYRLIDEKPRIGAGGAKIAFIHPKS
CCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCEEEEECCCH
VTGVLLELCERKE
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]