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The map label for this gene is argK [C]

Identifier: 18978319

GI number: 18978319

Start: 1799630

End: 1800595

Strand: Direct

Name: argK [C]

Synonym: PF1947

Alternate gene names: 18978319

Gene position: 1799630-1800595 (Clockwise)

Preceding gene: 18978318

Following gene: 18978320

Centisome position: 94.31

GC content: 40.06

Gene sequence:

>966_bases
ATGATAGACGACCTTGTAGAGAGAATGAGAAAAGGGGACAGAAGAGCCGTTGCTAGGCTAATAACCCTAGTAGAGAATGA
TGAAAAGAAGGCAAGAGAAATTATAAAAAGGATATACCCTCTAACTGGAAATGCCTATATAGTTGGAATAACTGGTCCTC
CTGGCTCAGGAAAGTCTACTCTGGTAGATAAATTGGTGAAAGAAGCAAGAAAAGAAGGACTAATAGTAGGTGTAATTGCC
GTAGATCCAACATCTCCCTTTACAGGTGGAGCATTGTTAGGTGATAGAATTAGGATGCAAGATCACGCAACTGACCCAGG
GGTTTTCATTAGAAGCATGGCTACTAGAGGGAGCCTAGGAGGATTAGCGAAGGCTACTAACGATGCAATAAAGATTCTAG
ATGCATATGGTTGTGATATAATTTTTGTTGAAACTGTTGGCGTTGGTCAAGTAGAAGTTGATATCGTGAAGACCGCTGAT
ACTGTTGTTTTAGTTACAGTTCCTGGGTTAGGGGATGATATTCAAGCTATAAAAGCTGGTCTTATGGAAATAGCTGATAT
ATTCGTTTTAAACAAGGCTGACAGGGAAGGAGCAGACGCAACTTACTTTGAACTCTCCCTTACCTTAGACTTAGAGAGCG
AAAAATGGGAAAAGCTCGGCTGGAGGCCACCTATAGTTGAAACAGTTGCAACTCTTGGAAAAGGTATCAAAGAACTTTGG
GAGCAGATAAAGAGGCATAGAGAGTTCCTAGAAAAATCCGGAAAATTAGAGGAAAAGAAAAGACTAAGAGTAGAAGAGGA
GATAAAGACCATTGTGTCCGATATGATAGCGAAAAAGGTTGAGGTTTCAATTAAGGCTGGAAATCTTGAAGATATTTTAG
AGAAGGTTATGAAAAAGGAACTAGATCCTTACTCTGCCGCTTCCCTTATCATGGAAAAAATAATTGGAGGTGGGAAGAGT
GTTTAA

Upstream 100 bases:

>100_bases
AATTGAGTTCATCGACAAAAACGTTGAAAAGCTCAAGAAGTTCAGATCCTCTACTTAATCCTTTTATATTGTTCTTGGAT
AATTTCTCCAGTGATGATGT

Downstream 100 bases:

>100_bases
GAAAATTGACCACGTTGGAATAGCTGTGAAGAATTTAGAAGAAGCCATTAAGATTTGGGAAGGGCTAGGACTAAAAGTTG
AGGAAATAGAAGAAGTTCCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MIDDLVERMRKGDRRAVARLITLVENDEKKAREIIKRIYPLTGNAYIVGITGPPGSGKSTLVDKLVKEARKEGLIVGVIA
VDPTSPFTGGALLGDRIRMQDHATDPGVFIRSMATRGSLGGLAKATNDAIKILDAYGCDIIFVETVGVGQVEVDIVKTAD
TVVLVTVPGLGDDIQAIKAGLMEIADIFVLNKADREGADATYFELSLTLDLESEKWEKLGWRPPIVETVATLGKGIKELW
EQIKRHREFLEKSGKLEEKKRLRVEEEIKTIVSDMIAKKVEVSIKAGNLEDILEKVMKKELDPYSAASLIMEKIIGGGKS
V

Sequences:

>Translated_321_residues
MIDDLVERMRKGDRRAVARLITLVENDEKKAREIIKRIYPLTGNAYIVGITGPPGSGKSTLVDKLVKEARKEGLIVGVIA
VDPTSPFTGGALLGDRIRMQDHATDPGVFIRSMATRGSLGGLAKATNDAIKILDAYGCDIIFVETVGVGQVEVDIVKTAD
TVVLVTVPGLGDDIQAIKAGLMEIADIFVLNKADREGADATYFELSLTLDLESEKWEKLGWRPPIVETVATLGKGIKELW
EQIKRHREFLEKSGKLEEKKRLRVEEEIKTIVSDMIAKKVEVSIKAGNLEDILEKVMKKELDPYSAASLIMEKIIGGGKS
V
>Mature_321_residues
MIDDLVERMRKGDRRAVARLITLVENDEKKAREIIKRIYPLTGNAYIVGITGPPGSGKSTLVDKLVKEARKEGLIVGVIA
VDPTSPFTGGALLGDRIRMQDHATDPGVFIRSMATRGSLGGLAKATNDAIKILDAYGCDIIFVETVGVGQVEVDIVKTAD
TVVLVTVPGLGDDIQAIKAGLMEIADIFVLNKADREGADATYFELSLTLDLESEKWEKLGWRPPIVETVATLGKGIKELW
EQIKRHREFLEKSGKLEEKKRLRVEEEIKTIVSDMIAKKVEVSIKAGNLEDILEKVMKKELDPYSAASLIMEKIIGGGKS
V

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=333, Percent_Identity=31.8318318318318, Blast_Score=169, Evalue=3e-42,
Organism=Escherichia coli, GI1789285, Length=280, Percent_Identity=36.0714285714286, Blast_Score=180, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI71994271, Length=341, Percent_Identity=30.2052785923754, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71994275, Length=283, Percent_Identity=31.4487632508834, Blast_Score=140, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 35151; Mature: 35151

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDDLVERMRKGDRRAVARLITLVENDEKKAREIIKRIYPLTGNAYIVGITGPPGSGKST
CHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHH
LVDKLVKEARKEGLIVGVIAVDPTSPFTGGALLGDRIRMQDHATDPGVFIRSMATRGSLG
HHHHHHHHHHHCCEEEEEEEECCCCCCCCCCHHCCHHHHCCCCCCCHHHHHHHHHCCCCC
GLAKATNDAIKILDAYGCDIIFVETVGVGQVEVDIVKTADTVVLVTVPGLGDDIQAIKAG
CHHHHCCHHHHHHHHCCCCEEEEEECCCCEEEEEEEECCCEEEEEEECCCCCHHHHHHHH
LMEIADIFVLNKADREGADATYFELSLTLDLESEKWEKLGWRPPIVETVATLGKGIKELW
HHHHHHHHHEECCCCCCCCCEEEEEEEEEECCHHHHHHCCCCCCHHHHHHHHHHHHHHHH
EQIKRHREFLEKSGKLEEKKRLRVEEEIKTIVSDMIAKKVEVSIKAGNLEDILEKVMKKE
HHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHH
LDPYSAASLIMEKIIGGGKSV
CCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIDDLVERMRKGDRRAVARLITLVENDEKKAREIIKRIYPLTGNAYIVGITGPPGSGKST
CHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHH
LVDKLVKEARKEGLIVGVIAVDPTSPFTGGALLGDRIRMQDHATDPGVFIRSMATRGSLG
HHHHHHHHHHHCCEEEEEEEECCCCCCCCCCHHCCHHHHCCCCCCCHHHHHHHHHCCCCC
GLAKATNDAIKILDAYGCDIIFVETVGVGQVEVDIVKTADTVVLVTVPGLGDDIQAIKAG
CHHHHCCHHHHHHHHCCCCEEEEEECCCCEEEEEEEECCCEEEEEEECCCCCHHHHHHHH
LMEIADIFVLNKADREGADATYFELSLTLDLESEKWEKLGWRPPIVETVATLGKGIKELW
HHHHHHHHHEECCCCCCCCCEEEEEEEEEECCHHHHHHCCCCCCHHHHHHHHHHHHHHHH
EQIKRHREFLEKSGKLEEKKRLRVEEEIKTIVSDMIAKKVEVSIKAGNLEDILEKVMKKE
HHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHH
LDPYSAASLIMEKIIGGGKSV
CCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]