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The map label for this gene is amzA

Identifier: 18978232

GI number: 18978232

Start: 1716895

End: 1717473

Strand: Reverse

Name: amzA

Synonym: PF1860

Alternate gene names: 18978232

Gene position: 1717473-1716895 (Counterclockwise)

Preceding gene: 18978233

Following gene: 33359577

Centisome position: 90.0

GC content: 39.21

Gene sequence:

>579_bases
GTGAGGGATATGATAATAGTAGTCCCAATTGGTGAAGTTCCTAGCGATGTTCTTTCTTTTCTTTCTGAAAATATTGAAAG
CTTTTACATGAAGTTTGGAATAGGAGTTAAGATTATTGGCAGCCTTCCAATCTCGGCGTTTTCTCATGCCTATGACTTTT
ATAGAAATCAGTATTTAGCTAGGCATTTTTTACCAGCCCTTTCCATCATAAGAAGGGATTATAAAGCCTTGGCAGTAATG
GGAGTTACGGAAGTTGATCTTTATGAGTCTGGCCTAAATTTTATCTTTGGCATAGCTCACCCTGGGTTTGGAGTTGCTTT
AATTTCTCTTCACAGGCTTTATCCAGAATTCTATGGAGAACCCCCAGATAGAAAACTTTTGAAGGAAAGGGCATTGAAAG
AGGCTATGCACGAGCTTGGTCACGTGTTTGGCTTGGAACATTGTCCGAATCCCAAGTGTGTAATGCATTTTTCAAACTCA
ATTATAGATACAGATATAAAGTCTTGGATGTATTGTAAGAACTGTCTTAGGAAACTTGAAGAGAGGCTGGGGAGGGGCTA
TGTACGAGGTAGAACTTAA

Upstream 100 bases:

>100_bases
TGCATTCCCAGGTTGAATTAGCTGATGCTAGAGATGTTGACAATACAATAAAACTTGCTAAGGCGTTACTTGAGGAGCTA
AAGCCAATGGACTTTACACC

Downstream 100 bases:

>100_bases
AGGATATGCAAACGATGAGATATTTGAGAGAGTTAGGGAGAAATTTGAGTTTATGAGGAGAGAGATTCATGAGGATATTT
ATTATCAACACCCCTGTAGG

Product: archaemetzincin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MRDMIIVVPIGEVPSDVLSFLSENIESFYMKFGIGVKIIGSLPISAFSHAYDFYRNQYLARHFLPALSIIRRDYKALAVM
GVTEVDLYESGLNFIFGIAHPGFGVALISLHRLYPEFYGEPPDRKLLKERALKEAMHELGHVFGLEHCPNPKCVMHFSNS
IIDTDIKSWMYCKNCLRKLEERLGRGYVRGRT

Sequences:

>Translated_192_residues
MRDMIIVVPIGEVPSDVLSFLSENIESFYMKFGIGVKIIGSLPISAFSHAYDFYRNQYLARHFLPALSIIRRDYKALAVM
GVTEVDLYESGLNFIFGIAHPGFGVALISLHRLYPEFYGEPPDRKLLKERALKEAMHELGHVFGLEHCPNPKCVMHFSNS
IIDTDIKSWMYCKNCLRKLEERLGRGYVRGRT
>Mature_192_residues
MRDMIIVVPIGEVPSDVLSFLSENIESFYMKFGIGVKIIGSLPISAFSHAYDFYRNQYLARHFLPALSIIRRDYKALAVM
GVTEVDLYESGLNFIFGIAHPGFGVALISLHRLYPEFYGEPPDRKLLKERALKEAMHELGHVFGLEHCPNPKCVMHFSNS
IIDTDIKSWMYCKNCLRKLEERLGRGYVRGRT

Specific function: Probable zinc metalloprotease

COG id: COG1913

COG function: function code R; Predicted Zn-dependent proteases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M54 family

Homologues:

Organism=Homo sapiens, GI75812974, Length=182, Percent_Identity=28.021978021978, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI75812972, Length=182, Percent_Identity=28.021978021978, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI75812970, Length=182, Percent_Identity=28.021978021978, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI75812968, Length=182, Percent_Identity=28.021978021978, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI75812966, Length=182, Percent_Identity=28.021978021978, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AMZA_PYRFU (Q8TZW5)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_579589.1
- ProteinModelPortal:   Q8TZW5
- MEROPS:   M54.001
- EnsemblBacteria:   EBPYRT00000004880
- GeneID:   1469739
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF1860
- NMPDR:   fig|186497.1.peg.1909
- GeneTree:   EBGT00050000022844
- HOGENOM:   HBG508786
- OMA:   DIKSWMY
- ProtClustDB:   PRK13267
- HAMAP:   MF_01842
- InterPro:   IPR012962
- InterPro:   IPR012091
- PIRSF:   PIRSF005785

Pfam domain/function: PF07998 Peptidase_M54

EC number: NA

Molecular weight: Translated: 21991; Mature: 21991

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 138-138

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDMIIVVPIGEVPSDVLSFLSENIESFYMKFGIGVKIIGSLPISAFSHAYDFYRNQYLA
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHH
RHFLPALSIIRRDYKALAVMGVTEVDLYESGLNFIFGIAHPGFGVALISLHRLYPEFYGE
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHHHCCC
PPDRKLLKERALKEAMHELGHVFGLEHCPNPKCVMHFSNSIIDTDIKSWMYCKNCLRKLE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHCCCHHHHHHHHHHHHHHHHHHHH
ERLGRGYVRGRT
HHHCCCCCCCCC
>Mature Secondary Structure
MRDMIIVVPIGEVPSDVLSFLSENIESFYMKFGIGVKIIGSLPISAFSHAYDFYRNQYLA
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHH
RHFLPALSIIRRDYKALAVMGVTEVDLYESGLNFIFGIAHPGFGVALISLHRLYPEFYGE
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHHHCCC
PPDRKLLKERALKEAMHELGHVFGLEHCPNPKCVMHFSNSIIDTDIKSWMYCKNCLRKLE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHCCCHHHHHHHHHHHHHHHHHHHH
ERLGRGYVRGRT
HHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA