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The map label for this gene is moaC

Identifier: 18978226

GI number: 18978226

Start: 1711295

End: 1711765

Strand: Reverse

Name: moaC

Synonym: PF1854

Alternate gene names: 18978226

Gene position: 1711765-1711295 (Counterclockwise)

Preceding gene: 33359577

Following gene: 18978224

Centisome position: 89.7

GC content: 38.43

Gene sequence:

>471_bases
ATGAAGCTAACTCATGTAGATGAAAAAGGAGTTAAGATGGTAGAAGTTGGACATAAGAAGGATATGTATAGGAGAGCCAT
AGCAAAGGGTCGAATTAAACTTAAGCCTGAAACTATAAAGCTCATTAGAGAGGGAAAAATTGAGAAGGGAAACGTTCTAG
CAGCTGCTCAAATTGCTGGAATATTAGCTGTGAAGAAGACCTTTGACATAATACCTCTTTGTCATCCAATTCCATTAACT
GGGGTTGATATAACCTTTGACTTTGGCGAAGACTACATTGAAGTTACATGTGAGGTTAGAGCTATTTACAAGACTGGAGT
AGAGATGGAAGCTTTAACAGGGGTTTCTGTGGCTCTCTTAACGATTTGGGACATGGTAAAGGCTGTAGAAAAAGATGAGA
AAGGCCAATATCCCTATACTAAAATAGAGGAGATAAGGGTTGTAGAGAAAATTAAAGAAGAACGCTCCTAG

Upstream 100 bases:

>100_bases
ACATTCCATTTGGTGAATCGGTGTCGTCAATACCTATGTGGATGAGCATCGATAAAGGCTCTTAAGGGATGCTTAAAAAT
AATATCCCAGGGGGTTAAAG

Downstream 100 bases:

>100_bases
TCATTGCTCCATCAAAGAGAATTGTAGAGCCTAGCATATATTCGGCGTTATCGCTAAGTAAGAATTCTATTAATTCTCCT
AGTTCTTCCCATTTTCCAGT

Product: putative molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MKLTHVDEKGVKMVEVGHKKDMYRRAIAKGRIKLKPETIKLIREGKIEKGNVLAAAQIAGILAVKKTFDIIPLCHPIPLT
GVDITFDFGEDYIEVTCEVRAIYKTGVEMEALTGVSVALLTIWDMVKAVEKDEKGQYPYTKIEEIRVVEKIKEERS

Sequences:

>Translated_156_residues
MKLTHVDEKGVKMVEVGHKKDMYRRAIAKGRIKLKPETIKLIREGKIEKGNVLAAAQIAGILAVKKTFDIIPLCHPIPLT
GVDITFDFGEDYIEVTCEVRAIYKTGVEMEALTGVSVALLTIWDMVKAVEKDEKGQYPYTKIEEIRVVEKIKEERS
>Mature_156_residues
MKLTHVDEKGVKMVEVGHKKDMYRRAIAKGRIKLKPETIKLIREGKIEKGNVLAAAQIAGILAVKKTFDIIPLCHPIPLT
GVDITFDFGEDYIEVTCEVRAIYKTGVEMEALTGVSVALLTIWDMVKAVEKDEKGQYPYTKIEEIRVVEKIKEERS

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=136, Percent_Identity=46.3235294117647, Blast_Score=115, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI32566331, Length=132, Percent_Identity=45.4545454545455, Blast_Score=106, Evalue=5e-24,
Organism=Drosophila melanogaster, GI28574490, Length=134, Percent_Identity=45.5223880597015, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28574492, Length=122, Percent_Identity=45.0819672131148, Blast_Score=102, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_PYRFU (Q8TZX1)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_579583.1
- ProteinModelPortal:   Q8TZX1
- SMR:   Q8TZX1
- EnsemblBacteria:   EBPYRT00000005369
- GeneID:   1469733
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF1854
- NMPDR:   fig|186497.1.peg.1903
- GeneTree:   EBGT00050000022601
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- ProtClustDB:   PRK12343
- HAMAP:   MF_01224_A
- InterPro:   IPR023045
- InterPro:   IPR023047
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17600; Mature: 17600

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: NA

Important sites: ACT_SITE 124-124

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTHVDEKGVKMVEVGHKKDMYRRAIAKGRIKLKPETIKLIREGKIEKGNVLAAAQIAG
CCCCCCCCCCCEEEECCCHHHHHHHHHHCCCEEECHHHHHHHHCCCCCCCCEEHHHHHHH
ILAVKKTFDIIPLCHPIPLTGVDITFDFGEDYIEVTCEVRAIYKTGVEMEALTGVSVALL
HHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEEHHEEEEECCCCCHHHHCCHHHHHH
TIWDMVKAVEKDEKGQYPYTKIEEIRVVEKIKEERS
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLTHVDEKGVKMVEVGHKKDMYRRAIAKGRIKLKPETIKLIREGKIEKGNVLAAAQIAG
CCCCCCCCCCCEEEECCCHHHHHHHHHHCCCEEECHHHHHHHHCCCCCCCCEEHHHHHHH
ILAVKKTFDIIPLCHPIPLTGVDITFDFGEDYIEVTCEVRAIYKTGVEMEALTGVSVALL
HHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEEHHEEEEECCCCCHHHHCCHHHHHH
TIWDMVKAVEKDEKGQYPYTKIEEIRVVEKIKEERS
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA