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The map label for this gene is aroK

Identifier: 18978066

GI number: 18978066

Start: 1573779

End: 1574600

Strand: Direct

Name: aroK

Synonym: PF1694

Alternate gene names: 18978066

Gene position: 1573779-1574600 (Clockwise)

Preceding gene: 18978065

Following gene: 18978067

Centisome position: 82.47

GC content: 39.9

Gene sequence:

>822_bases
TTGCGTGGCTTAGGGAAAGGAAGTAGTGCAATAACTGTCGTTAATGCTTTTGCAACTGGAAAAGGCGGAGCTATTGGAAT
AGACCTATGGACTGAGGCCAAGGTAAAGATAACAGACGGAGAAGTTAAAGGGAAAATTCTTGTAAACGGGTTAGAATTCA
ACGATTTTAGAGTAGTAAATGCCGTTTTGGATGTAATGAGGAGGTATTCTGGGATAGAATTTGGAATAGAGTTCGAGATA
AACTCTGAAATACCCGTAGGAAAAGGTCTAAAAAGTAGCTCTGCCGTAGCAAATGCTCTTGTAGAAGCAATAGCAAGGGC
TCTTCGCTTAAATATTCCCGGAATAAAGGTCGTAAAGCTTGGAGTTGAGGCAGCGAAAAAAGCAGGGGTAACATTGACGG
GAGCTTTTGACGATGCTTGTGCCTCTTATTTTGGAGGTTTGTGCCTAACAGATAATCTAAGAGTTGAACTACTTAAGAGA
ATTGAAATTGATGAGTTGCCAGTGGTAATTTTAGTTCCAAATGAGACAGTTCTTACAGAAGAGCTGAAAGGGGTAGATTT
CCTAAAAATAGCCCCCTATGTTGAGGAAGCATTCAAGCTTGCAATTAAAGGGGAATGGAAAAAGGCACTTGTTTTAAACG
GATTGATATACTCAACATTTCTAAGCTATCCTCCTGAACCCATATCCAAAGCCTTACATCTTGGAGCTGTAGTGGGGTTA
AGTGGAAAAGGACCAAGTGTATTTGCAATTACAGATGAACCGGAGAGGATAGAAGAAGTTTGGAGAGAATTTGGAGATGT
TATAATTACTTCAACAAGATAA

Upstream 100 bases:

>100_bases
GCTATTGATGGACTTTGGATGCTAGTCTATCAAGGAGCAGAGAGTTTTAGACTTTGGACTGGAGAGGAGGGAGACGTAGA
ACTTATGAGGAGGGTCGCCC

Downstream 100 bases:

>100_bases
GACGAAAAAGATAAATCCTGAAACATGATTTATTTTTGGTGATACTAAGATGAGAAAGGTAGGAATTACACTTTCTGTAG
TTGCTCTAGTAATAATGGGA

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MRGLGKGSSAITVVNAFATGKGGAIGIDLWTEAKVKITDGEVKGKILVNGLEFNDFRVVNAVLDVMRRYSGIEFGIEFEI
NSEIPVGKGLKSSSAVANALVEAIARALRLNIPGIKVVKLGVEAAKKAGVTLTGAFDDACASYFGGLCLTDNLRVELLKR
IEIDELPVVILVPNETVLTEELKGVDFLKIAPYVEEAFKLAIKGEWKKALVLNGLIYSTFLSYPPEPISKALHLGAVVGL
SGKGPSVFAITDEPERIEEVWREFGDVIITSTR

Sequences:

>Translated_273_residues
MRGLGKGSSAITVVNAFATGKGGAIGIDLWTEAKVKITDGEVKGKILVNGLEFNDFRVVNAVLDVMRRYSGIEFGIEFEI
NSEIPVGKGLKSSSAVANALVEAIARALRLNIPGIKVVKLGVEAAKKAGVTLTGAFDDACASYFGGLCLTDNLRVELLKR
IEIDELPVVILVPNETVLTEELKGVDFLKIAPYVEEAFKLAIKGEWKKALVLNGLIYSTFLSYPPEPISKALHLGAVVGL
SGKGPSVFAITDEPERIEEVWREFGDVIITSTR
>Mature_273_residues
MRGLGKGSSAITVVNAFATGKGGAIGIDLWTEAKVKITDGEVKGKILVNGLEFNDFRVVNAVLDVMRRYSGIEFGIEFEI
NSEIPVGKGLKSSSAVANALVEAIARALRLNIPGIKVVKLGVEAAKKAGVTLTGAFDDACASYFGGLCLTDNLRVELLKR
IEIDELPVVILVPNETVLTEELKGVDFLKIAPYVEEAFKLAIKGEWKKALVLNGLIYSTFLSYPPEPISKALHLGAVVGL
SGKGPSVFAITDEPERIEEVWREFGDVIITSTR

Specific function: Unknown

COG id: COG1685

COG function: function code EH; Archaeal shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROK_PYRFU (Q8U0A5)

Other databases:

- EMBL:   AE009950
- RefSeq:   NP_579423.1
- ProteinModelPortal:   Q8U0A5
- EnsemblBacteria:   EBPYRT00000005662
- GeneID:   1469571
- GenomeReviews:   AE009950_GR
- KEGG:   pfu:PF1694
- NMPDR:   fig|186497.1.peg.1742
- GeneTree:   EBGT00050000022726
- HOGENOM:   HBG646614
- OMA:   AFDDACA
- ProtClustDB:   PRK01123
- BRENDA:   2.7.1.71
- GO:   GO:0005737
- HAMAP:   MF_00370
- InterPro:   IPR006204
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR010189
- Gene3D:   G3DSA:3.30.230.10
- PIRSF:   PIRSF005758
- TIGRFAMs:   TIGR01920

Pfam domain/function: PF00288 GHMP_kinases_N; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =2.7.1.71

Molecular weight: Translated: 29318; Mature: 29318

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00627 GHMP_KINASES_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGLGKGSSAITVVNAFATGKGGAIGIDLWTEAKVKITDGEVKGKILVNGLEFNDFRVVN
CCCCCCCCCEEEEEEEEECCCCCEEEEEEECCEEEEEECCCEECEEEEEECCCCHHHHHH
AVLDVMRRYSGIEFGIEFEINSEIPVGKGLKSSSAVANALVEAIARALRLNIPGIKVVKL
HHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEE
GVEAAKKAGVTLTGAFDDACASYFGGLCLTDNLRVELLKRIEIDELPVVILVPNETVLTE
CHHHHHHCCEEEEECCHHHHHHHHCCEEEECCHHHHHHHHCCCCCCCEEEEECCCEEEHH
ELKGVDFLKIAPYVEEAFKLAIKGEWKKALVLNGLIYSTFLSYPPEPISKALHLGAVVGL
HHCCCCEEEECHHHHHHHEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEE
SGKGPSVFAITDEPERIEEVWREFGDVIITSTR
CCCCCEEEEECCCHHHHHHHHHHHCCEEEEECC
>Mature Secondary Structure
MRGLGKGSSAITVVNAFATGKGGAIGIDLWTEAKVKITDGEVKGKILVNGLEFNDFRVVN
CCCCCCCCCEEEEEEEEECCCCCEEEEEEECCEEEEEECCCEECEEEEEECCCCHHHHHH
AVLDVMRRYSGIEFGIEFEINSEIPVGKGLKSSSAVANALVEAIARALRLNIPGIKVVKL
HHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEE
GVEAAKKAGVTLTGAFDDACASYFGGLCLTDNLRVELLKRIEIDELPVVILVPNETVLTE
CHHHHHHCCEEEEECCHHHHHHHHCCEEEECCHHHHHHHHCCCCCCCEEEEECCCEEEHH
ELKGVDFLKIAPYVEEAFKLAIKGEWKKALVLNGLIYSTFLSYPPEPISKALHLGAVVGL
HHCCCCEEEECHHHHHHHEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEE
SGKGPSVFAITDEPERIEEVWREFGDVIITSTR
CCCCCEEEEECCCHHHHHHHHHHHCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA